Dr. Sanaa Ahmed Ali Ibrahim
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Dr. Sanaa Ahmed Ali Ibrahim

Professor
Therapeutic Chemistry Department, National Research Centre Dokki, Giza, Egypt

Highest Degree
Ph.D. in Zoology from Ain Shams University, Cairo, Egypt

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Biography

Dr. Sanaa Ahmed Ali Ibrahim is currently working as Professor at National Research Center, Dokki, Cairo, Egypt. She obtained her Ph.D. in Zoology from Ain Shams University, Cairo, Egypt. Her area of interest related to Biochemistry. Her area of expertise includes Histochemistry, Electrophoresis, Renal Protective, Proteins, Diabetes, Histopathology, Liver Cancer, Hepatoprotective, and Breast Cancer. She is also serving as reviewer and editor board member in number of journals. She supervised 4 Masters Thesis, and 2 PhD and 3 Masters Students currently in her supervision. She is member of Egyptian Society for Biochemistry and Molecular Biology, Biochemistry Department, Kasr Al Anini, Faculty of Medicine, The Arab Society of Medical Research, and Arab Women in Science. She also completed number of research project. She also attended number of workshops and conferences. She has published 34 research articles in journals as author/co-author.

Area of Interest:

Biomedical Sciences
100%
Biochemistry
62%
Histochemistry
90%
Proteins
75%
Histopathology
55%

Research Publications in Numbers

Books
3
Chapters
1
Articles
68
Abstracts
0

Selected Publications

  1. Sroor, F.M., W.M. Basyouni, H.F. Aly, S.A. Ali and A.F. Arafa, 2022. Design, synthesis and SAR of novel sulfonylurea derivatives for the treatment of diabetes mellitus in rats. Med. Chem. Res., 31: 195-206.
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  2. Hamed, M.A., A.F.A. Naser, A.M. El-Feky, M.M. Elbatanony and S.E. Shaker et al., 2022. Phytoconstituents of red grape seeds extract as inflammatory modulator in adjuvant arthritic rats: Role Of IL-1 and its receptor blocking. J. Biol. Active Prod. Nat., 12: 254-275.
    CrossRef  |  Direct Link  |  
  3. Ali, S.A., S.M. Gooda, A.F.A. Naser, E.A. Younis and M.A. Hamed et al., 2022. Chromosomal aberrations, DNA damage, and biochemical disturbances induced by silver nanoparticles in mice: Role of particle size and natural compounds treatment. Biomarkers, 27: 349-360.
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  4. El-Gendy, M.M.A.A., K.G. Abdel-Wahhab, N.S. Hassan and E.A. El-Bondkly et al., 2021. Evaluation of carcinogenic activities and sperm abnormalities of Gram-negative bacterial metabolites isolated from cancer patients after subcutaneous injection in albino rats. Antonie van Leeuwenhoek, 114: 287-302.
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  5. Basyouni, W.M., S.Y. Abbas, K.A.M. El-Bayouki, E.A. Younis, S.A. Ali and H.F. Aly, 2021. Synthesis and hyperglycemic, biochemical and histopathological evaluation of novel sulfonylbiguanide and sulfonylurea derivatives as potent anti-diabetic agents. Bioorg. Chem., Vol 117. 10.1016/j.bioorg.2021.105418.
    CrossRef  |  Direct Link  |  
  6. Rizk, M.Z., S.A. Ali, M.O. Kadry, G.I. Fouad, N.N. Kamel, E.A. Younis and S.M. Gouda, 2020. C-reactive protein signaling and chromosomal abnormalities in nanotoxicity induced via different doses of TiO2 (80 nm) boost liver function. Biol. Trace Elem. Res., 198: 157-167.
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  7. Motawi, T.K., N.A. H. Sadik, M.A. Hamed, S.A. Ali, W.K.B. Khalil and Y.R. Ahmed, 2020. Potential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson’s disease mice model. Mol. Cell. Biochem., 465: 89-102.
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  8. Hamed, M.A., A.F.A. Naser, W.M. Aziz, F.M. Ibrahim, S.A. Ali, N.S. El-Rigal and W.K.B. Khalil, 2020. Natural sources, dopaminergic and non-dopaminergic agents for therapeutic assessment of Parkinsonism in rats model. PharmaNutrition, Vol. 11. 10.1016/j.phanu.2019.100171.
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  9. Ali, S.A., A.F. Arafa, H.F. Aly, N.A. Ibrahim and M.O. Kadry, 2020. DNA damage and genetic aberration induced via different sized silver nanoparticles: therapeutic approaches of Casimiroa edulis and Glycosmis pentaphylla leaves extracts. J. Food Biochem., Vol. 43. 10.1111/jfbc.13398.
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  10. Mohammed, M.M.D., N.A. Ibrahim, S.A. Ali, M.A. Hamed| and N.S. El-Rigal, 2018. Triacylglycerols of the seed oil of Linum grandiflorum desf.: Their composition, cytotoxicity, and hepatoprotective activity. J. Food Biochem., 10.1111/jfbc.12525.
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  11. Rizk, M. Z., S.A. Ali, M.A. Hamed, N.S. El-Rigal, H.F.Aly and H.H. Salah, 2017. Toxicity of titanium dioxide nanoparticles: Effect of dose and time on biochemical disturbance, oxidative stress and genotoxicity in mice Biomed. Pharmacother., 90: 466-472.
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  12. Aly, H.F., H.I. Abd-Alla, S.A. Ali, RA. Alez, M.T. Abu-Krisha and M.M. Mamdooh, 2017. Bioinformatics: Inflammatory cytokines and attenuation of diabetes hypercholesterolemia-induced renal injury using morning glory and necklace pod extracts. Asian J. Pharm. Clin. Res., 10: 347-355.
  13. Al-Ashaal, H.A.A.H., H.F.A. Abduallah, A.A. Farghaly, S.A. Ali, N.S. El-Rega and M.A.E.A. Hamed, 2017. In vitro produced glycoalkaloids from Solanum nigrum L. and evaluation of their potential role as antibilharziasis. Asian Pac. J. Trop. Dis., 7: 169-180.
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  14. Ibrahim, N.A., M.M. Mohamed, H.F. Aly and S.A. Ali, 2016. Hypoglycemic effect of mucilage and methanol extract of Aegle marmelos (l.) correa fruits in stereptozotocin indused diabetic rats. Der. Pharma. Chemica., 8: 1-15.
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  15. Aly, H.F., H.I. Abd-Alla, S.A. Ali, M.M. Mamdooh, R.A. Alez and M.T. Abu-Krisha, 2016. Statistical data analysis which result from the bio-diagnosis and bio-treatment of injured rats with the hyperlipidemia and hyperglycemia diseases. Asian J. Pharm. Clin. Res., 9: 122-130.
    CrossRef  |  
  16. Taie, H.A.A., H.I. Abd-Alla, A.A. Sanaa and F.A. Hanan, 2015. Chemical composition and biological activities of two solanum tuberosum cultivars grown in Egypt. Int. J. Pharm. Pharm. Sci., 7: 311-320.
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  17. Matloub, A.A., S.M.E. Sahar, W.M. El-Senousy, H. Manal and F.A. Hanan et al., 2015. In vitro antiviral, cytotoxic, antioxidant and hypolipidemic activites of polysaccharide isolated from marine algae. Int. J. Pharmacogn. Phytochem. Res., 7: 1099-1111.
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  18. Ibrahim, N.A., S. Seham, S.E. El-Hawary, S.A. Ali, M.M.D. Mohammed and E.E. Refaat, 2015. Chemical constituents of Paulownia tomentosa (Thunb) steud. Fam. Scrophulariaceae and its role against hyperglycemia. World J. Pharm. Res., 4: 2445-2466.
  19. Ali, S.A., S.A. Ahmed and A.R.H. Farrag, 2015. Protective and prophylactic role of brassicaceae vegetables extracts on n-nitrosodiethylamine induced initiation of hepatocellular carcinoma in rat liver. Res. Rev. J. Pharmacol. Toxicol. Stud., 3: 10-19.
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  20. Ali, S.A., N.S. El-Rigal and S.M. Saeed, 2015. Antischistosomal activity of two active constituents isolated from the leaves of egyptian medicinal plants. Inf. Dis. Res. Treat., 8: 5-16.
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  21. Ali, S.A., M.Z. Rizk, S.A. Abdelazim, H.A. Darwish and M.O. Kadry, 2015. Role of potent antioxidants in regulation of smad-2 transcription and tgf-β1 signaling in nano sized titanium dioxide-induced oxidative injury in mice liver. Inter. J. Pharm., 5: 17-26.
  22. Al-Ashaal, H.A., H.F. Aly, M.A. Hamed, S.A. Ali, N.S. EL-regal and A.A. Farghaly, 2015. Assessment of saponin rich fraction from Balanites aegyptiaca (L.) fruits as anti schistomiasis, anti-oxidant, antimutagenic agents and in vitro production of saponins for drug manufacture. Eur. Sci. J., ESJ, 11: 95-128.
  23. Ahmed, H.H., F.A. Hanan and A.A. Sanaa, 2015. Potential impact of coq10 and vitamin eagainst (stz) induced metabolic deterioration in the albino rats. Int. J. Pharm. Pharm. Sci., 7: 1-9.
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  24. Abdelazim, S.A., H.A. Darwish, S.A. Ali, M.Z. Rizk and M.O. Kadry, 2015. Potential antifibrotic and angiostatic impact of idebenone, carnosine and vitamin e in nano-sized titanium dioxide-induced liver injury. Cell. Physiol. Biochem., 35: 2402-2411.
  25. Abdel Azim, S.A., H.A. Darwish, M.Z. Rizk, S.A. Ali and M.O. Kadry, 2015. Amelioration of titanium dioxide nanoparticles-induced liver injury in mice: Possible role of some antioxidants. Exp. Toxicol. Pathol., 67: 305-314.
    CrossRef  |  Direct Link  |  
  26. Hamed, M.A., H.F. Aly, S.A. Ali, N.S. El-Rigal and N.S. Metwally et al., 2014. Performance of DNA of susceptible and resistant biomphalaria alexandrina snails as immunogens in schistosoma mansoni infected mice. World J. Pharm. Res., 3: 25-53.
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  27. Bekheet, S.A., M.K. El-Bahr, S.A. Ali and M.A. Hamed, 2014. Callus production of globe artichoke and milk thistle: In vitro hypolipidemic and antioxidant activities. World J. Pharm. Res., 3: 1-17.
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  28. Awad, N.E., S.A. Ali, M.A. Hamed, A.A. Seida and M.M. Elbatanony, 2014. Assessment of Ficus Spp. in improving the metabolic syndrome secondary to hypercholesterolemia in rats fed with high-fat diet. Int. J. Pharm. Clin. Res., 6: 165-173.
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  29. Ali, S.A., 2014. Effects food and nutritional components in focus: Beneficial effect of carnosine. Int. J. Clin. Toxicol., 2: 21-30.
  30. Mohamed, N.Z., M.A. Abd El Kader and S.A. Ali, 2013. Efficacy of L-carnosine against Schistosoma mansoni Antigens in Liver, Heart, Kidney and Brain of Rabbits. J. Appl. Pharm. Sci., 3: 39-45.
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  31. Hamed, M.A., N.S. El-Rigal and S.A. Ali, 2013. Effects of black seed oil on resolution of hepato-renal toxicity induced by bromobenzene in rats. Eur. Rev. Med. Pharm. Sci., 17: 569-581.
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  32. Hamed, M.A. and S.A. Ali, 2013. Non-viral factors contributing to hepatocellular carcinoma. World J. Hepatol. 5: 311-322.
    PubMed  |  Direct Link  |  
  33. Ali, S.A., M.A. Hamed and N.S. El Rigal, 2013. Research and reviews: journal of pharmacology and toxicological studies. J. Pharmacol. Toxicol. Stud., 2: 21-32.
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  34. Ali, S.A., L.M. Faddah and M.H. Nazmy, 2013. Role of Anserine Against Υ-Radiation Along With or Without Zinc: Hepatoprotective Action of Anserine Against Gamma Radiation Along With or Without Zinc on Rat Liver, LAP Lambert Academic Publishing, Germany, Pages:336, ISBN 978-3-659-46226-9.
  35. Hamed, M.A., S.A. Ali and N.S. El-Rigal, 2012. Therapeutic potential of ginger against renal injury induced by carbon tetrachloride in rats. Sci. World J. Art., .
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  36. Hamed, M.A., H.F. Aly, S.A. Ali, N.S. Metwalley, S.A. Hassan and S.A. Ahmed, 2012. In vitro and in vivo assessment of some functional foods against initiation of hepatocellular carcinoma. J. Basic Applied Sci. Res., 2: 471-483.
    Direct Link  |  
  37. El-Rigal, N.S., S.A. Ali, M.S. Abd-Allah, M.E. El-Sayed and S.M. Saeed et al., 2012. D-mannitol in ameliorating some metabolic disorders in Schistosoma mansoni infected mice. Egypt. Pharm. J., 10: 137-166.
  38. Donya, S.M., A.A. Farghaly, M.A. Abo-Zeid, H.F. Aly and S.A. Ali et al., 2012. Malachite green induces genotoxic effect and biochemical disturbances in mice. Eur. Rev. Med. Pharm. Sci., 16: 469-482.
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  39. Ali, S.A., M.Z. Rizk and M.M. Mostafa, 2012. Hepatoprotective Effects of Medicinal Plants on Ccl4 Liver Toxicity: Study of the Hepatoprotective Effects of Two Traditional Medicinal Plants on Carbon Tetrachloride Induced Liver Toxicity. Lambert Academic Publishing AG and Co., KG., Germany.
  40. Ali, S.A., L.M. Fadda, H. Elebiary and M. Soliman, 2012. Evaluation of the radioprotective action of anserine along with zinc in albino rats exposed to gammaradiation. J. Applied Pharm. Sci., 2: 115-122.
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  41. Ali, S.A., L. Faddah, A. Abdel-Baky and A. Bayoumi, 2012. L-Carnitine And Coq10 Role In Combating Deteriorative Effect of CCL4: β-Hydroxy-γ-Trimethylammonium Butyrate and Ubiquinone in combating the Deteriorative Effect Induced by CCl4 in Rat. Publisher LAP Lambert Academic Publishing AG and Co, KG., Germany.
  42. Ali, S.A., H.F. Aly, L.M. Faddah and Z.F. Zaidi, 2012. Dietary supplementation of some antioxidants against hypoxia. World J. Gastroenterol., 18: 6379-6386.
    CrossRef  |  Direct Link  |  
  43. Ali, S.A., 2012. Evaluation of immunological effect of beta alanyl-l-histidine against Schistosoma mansoni antigens of rabbits. J. Infect. Dev. Ctries., 61: 166-175.
    PubMed  |  Direct Link  |  
  44. Saeed, S.M., N.S. El-rigal and S.A. Ali, 2011. New Natural Active Constituents Against Schistosoma mansoni: Effect of New Natural Active Constituents on some Metabolic Disorders in Schistosoma mansoni Infected Mice. Lambert Academic Publishing, AG., Co., KG., Germany, ISBN: 9783847311331, Pages: 248.
  45. Metwally, N.S., S.A. Ali, A.M. Mohamed, H.M. Khaled and S.A. Ahmed, 2011. Levels of certain tumor markers as differentialfactors between bilharzial and non-biharzial bladder cancer among Egyptian patients. Cancer. Cell. Int., .
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  46. Ali, S.A., M.A. Hamed, N.S. El-Rigal, M.H. Shabana and M.E.S. Kassem, 2011. Chemical composition of Argyreia speciosa Fam. Convolvulaceae and it's role against hyperglycemia. J. Applied Pharm. Sci., 1: 76-84.
  47. Ali, S.A., 2011. Natural products as therapeutic agents for schistosomiasis. Res. J. Med. Plant, 5: 1-20.
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  48. Maghraby, A.S., M.A. Hamed, H.F. Ali and S.A. Ali, 2010. Antischistosomal activity of Fasciola gigantic eggs influenced by Egyptian saponin extracted from Atriplex nummularia. J. Am. Sci., 6: 368-381.
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  49. Maghraby, A.S., M.A. Hamed and S.A. Ali, 2010. Bioimmunological response to Schistosoma mansoni and Fasciola gigantica worm homogenates either mixed with or without saponin. J. Infect. Dev. Countries, 4: 334-344.
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  50. Hamed, M.A., S.A. Ali, H.F. Aly, N.S. El-Rigal and M.Z. Rizk, 2010. Biomphalaria alexandrina snails as immunogens against Schistosoma mansoni infection in mice. Mem. Inst. Oswaldo Cruz., 105: 879-888.
    CrossRef  |  PubMed  |  Direct Link  |  
  51. Ali, S.A., M.Z. Rizk, N.A. Ibrahim, M.S. Abdallah, H.M. Sharara and M.M. Moustafa, 2010. Protective role of Juniperus phoenicea and Cupressus sempervirens against CCl4. World J. Gastrointest. Pharmacol. Ther., 1: 123-131.
    CrossRef  |  PubMed  |  Direct Link  |  
  52. Ali, S.A., L.L. Faddah, A. Abdel-Baky and A. Bayoumi, 2010. Protective effect of L-carnitine and coenzyme Q10 on CCl4-induced liver injury in rats. Scientia Pharmceutica, 78: 881-896.
    CrossRef  |  
  53. Ali, S.A., M.A. Hamed and N.S. El-Rigal, 2009. Therapeutic effect of L-carnosine on metabolic syndrome induced by hypercholesterolemia. The New Egypt. J. Med., 41: 39-49.
  54. Rizk, M.Z., M.S. Abdallah, H.M. Sharara, S.A. Ali, N.A. Ibrahim and M.M. Moustafa, 2007. Efficiency of Cupressus sempiverens L. and Juniperus phoenicea against carbon tetrachloride hepatotoxicity in rats. Trends Med. Res., 2: 83-94.
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  55. El-Banhawey, M.A., M.A. Ashry, A.K. EL-Ansary and S.A. Aly, 2007. Effect of Curcuma longa or parziquantel on Schistosoma mansoni infected mice liver-histological and histochemical studies. Indian J. Exp. Biol., 45: 877-889.
    PubMed  |  
  56. El-Ansary, K.A., S.A. Ahmed and S.A. Aly, 2007. Antischistosomal and liver protective effects of Curcuma longa extract in Schistosoma mansoni infect mice. Indian J. Exp. Biol., 45: 791-801.
    PubMed  |  
  57. Soliman, K.M., M.A. Hamed and S.A. Ali, 2006. Hepatoprotective effect of carnosine on liver biochemical parameters in chronic ethanol intoxicated rat. J. Medical Sci., 6: 528-536.
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  58. El-Rigal, N.S., S.A. Aly, M. Rizk and A. Said, 2006. Effect of Ailanthus altissima and Ziziphus spina christi extracts on some hepatic marker enzymes and antioxidants in Schistosoma mansoni infected mice. Pol. J. Food Nutr. Sci., 15: 199-206.
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  59. Aly, S.A., N.S. El-Rigal and M.Z. Rizk, 2006. Nutritional supplementation with Ailanthus altissima and Ziziphus spina christi to compensate for some metabolic disorders in Schistosoma mansoni infected mice. Pak. J. Biol. Sci., 9: 1700-1706.
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  60. Aly, H.F. and S.A. Aly, 2006. Essential role of Citrus reticulata and Mirazid in treatment of Schistosoma mansoni infected mice: Biochemical and parasitological studies. Pol. J. Food Nutr. Sci., 15: 461-467.
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  61. Ali, S.A. and M.A. Hamed, 2006. Effect of Ailanthus altissima and Zizyphus spina-christi on bilharzial infestation in mice: Histological and histopathological studies. J. Applied Sci., 6: 1437-1446.
    CrossRef  |  Direct Link  |  
  62. Aly, S.A., N.S. El-Rigal, S.A. Ahmed and H.M. Khaled, 2005. Biochemical alterations in serum of bladder cancer patients with and without schistosomiasis. J. Genet. Eng. Biotechnol., 3: 59-71.
  63. Hamed, M.A. H.F. Aly, S.A. Aly and A.S. Maghraby, 2004. Prophylactic effect of Pulicaria crispa and Citharexylum quadrangular Jacq extracts on some liver enzymes representing different metabolic pathways in Schistosoma mansoni infected mice. Egypt. J. Schitisomaiasis Infect. Endem. Dis., 26: 19-40.
  64. Aly, S.A., H.F. Aly, N. Saba-el-Rigal and E.M. Sammour, 2004. Induced changes in biochemical parameters of the molluscan tissues non-infected using two potent plants molluscicides. J. Egypt Soc. Parasitol., 34: 527-542.
    PubMed  |  
  65. Aly, S.A., 2004. Evaluation of the hepatoprotective effect of DDB and antioxidants in CCl4 intoxicated rats. Egypt Pharm. J., 2: 27-45.
  66. Soliman, K.M., H.F. Aly and S.A. Aly, 2003. Stimulatory effect of carnosine on serum proteins in ethanol intoxicated rats. Egypt. J. Pharm. Sci., 44: 267-291.