Dr. Mahmoud Kandeel
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Dr. Mahmoud Kandeel

Associate Professor
Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Saudi Arabia

Highest Degree
Ph.D. in Drug Discovery and Molecular Biology from Gifu University, Gifu, Japan

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Area of Interest:

Pharmacology and Toxicology
100%
Molecular Pharamcology
62%
Drug Discovery
90%
Molecular Parasitology
75%
Molecular Biochemistry
55%

Research Publications in Numbers

Books
4
Chapters
2
Articles
210
Abstracts
15

Selected Publications

  1. Haddadi, H., M. Marzok, H. Moharam, M. Rizk and M. Kandeel et al., 2025. Expression of vitamin D receptor gene (VDR) and associated cytokine response in Arabian horses with chronic inflammatory airway disease. Egypt. J. Vet. Sci., 56: 11-20.
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  2. Meligy, A.M.A., W.R. El-Ghareeb, S.M. Abdel-Raheem, H.A.A. Ismail and W.S. Darwish et al., 2024. Assessment of some toxic elements (Co, Cr, Mn, Se, and As) in muscle, offal, hair and blood of camels (Camelus dromedaries) and their risk assessment. Open Vet. J., 14: 154-163.
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  3. Kandeel, M., M. Yamamoto, A. Al-Taher, A. Watanabe and K. Oh-Hashi et al., 2024. Erratum to "small molecule inhibitors of middle east respiratory syndrome coronavirus fusion by targeting cavities on heptad repeat trimers" [Biomol Ther 28(4), 311-319 (2020)]. Biomol. Ther., 32: 262-265.
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  4. Attiq, A., S. Afzal, W. Ahmad and M. Kandeel, 2024. Hegemony of inflammation in atherosclerosis and coronary artery disease. Eur. J. Pharmacol., Vol. 966. 10.1016/j.ejphar.2024.176338.
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  5. Alruhaili, M.H., M. Marzok, H.S. Gattan, M. Salem, M. Kandeel and A. Selim, 2024. Prevalence and potential risk factors for Cryptosporidium spp. infection in horses from Egypt. Comp. Immunol. Microbiol. Infect. Dis., Vol. 106. 10.1016/j.cimid.2024.102140.
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  6. Al-Mubarak, A.I.A., A.A.G. Al-Kubati, A. Sheikh, A.M. Abdelaziz and J. Hussen et al., 2024. Detection of avian orthoavulavirus-1 genotypes VI.2.1 and VII.1.1 with neuro-viscerotropic tropism in some backyard pigeons (Columbidae) in Eastern Saudi Arabia. Front. Vet. Sci., Vol. 11. 10.3389/fvets.2024.1352636.
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  7. Abd El-Lateef, H.M., M.M. Khalaf, M. Kandeel and M. Gouda, 2024. Facile green fabrication of copper/polyvinylidene fluoride nanocomposite for pathogens disinfection and dye degradation in wastewater. Inorg. Chem. Commun., Vol. 161. 10.1016/j.inoche.2024.112119.
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  8. Selim, A., M. Marzok, K. Alkashif, M. Kandeel, M. Salem and M.Z. Sayed-Ahmed, 2023. Bluetongue virus infection in cattle: Serosurvey and its associated risk factors. Trop. Anim. Health Prod., Vol. 55. 10.1007/s11250-023-03701-5.
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  9. Marzok, M., M. Kandeel, K. Alkhodair, S. Abdel-Raheem and H. Ismail et al., 2023. Evaluation of cardiac indices using M-mode echocardiography after administration of metoclopramide and ondansetron in donkeys (Equus asinus): An experimental study. Front. Vet. Sci., Vol. 10. 10.3389/fvets.2023.1189710.
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  10. Kitamura, Y., M. Kandeel, E. Oba, C. Iwai and K. Iritani et al., 2023. A diversifiable synthetic platform for the discovery of new carbasugar SGLT2 inhibitors using azide-alkyne click chemistry. Chem. Pharm. Bull., 71: 240-249.
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  11. Kandeel, S., M. Kandeel and R.S. Estfanous, 2023. Effect of morin on fluoxetine (Prozac)-induced structural changes of mice skeletal muscle: Light and electron microscopic study. Egypt. J. Histol., 46: 178-192.
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  12. Kandeel, M., S. Latha, K. Subramanian, D. Rennita and R. Thirunavukkarasu et al., 2023. Chitosan/alginate nanocomposite with Fe nanoparticles for the efficient removal of hexavalent chromium pollutant. J. Nanomater., Vol. 2023. 10.1155/2023/1713690.
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  13. Kandeel, M., M.N. Iqbal, I. Ali, S. Malik, A. Malik and S.A. Sehgal, 2023. Comprehensive in silico analyses of flavonoids elucidating the drug properties against kidney disease by targeting AIM2. PLoS ONE, Vol. 18. 10.1371/journal.pone.0285965.
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  14. Kandeel, M., M.A. Morsy, H.M. Abd El-Lateef, M. Marzok and H.S. El-Beltagi et al., 2023. Cognitive- and memory-enhancing effects of Augmentin in Alzheimer's rats through regulation of gene expression and neuronal cell apoptosis. Front. Pharmacol., Vol. 14. 10.3389/fphar.2023.1154607.
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  15. Kandeel, M., M.A. Morsy, H.M. Abd El-Lateef, M. Marzok and H.S. El-Beltagi et al., 2023. A century of “anticoccidial drugs”: Bibliometric analysis. Front. Vet. Sci., Vol. 10. 10.3389/fvets.2023.1157683.
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  16. Kandeel, M., M.A. Morsy, H.M. Abd El-Lateef, M. Marzok and H.S. El-Beltagi et al., 2023. A century of “Camel Research”: A bibliometric analysis. Front. Vet. Sci., Vol. 10. 10.3389/fvets.2023.1157667.
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  17. Kandeel, M., 2023. An overview of the recent progress in Middle East Respiratory Syndrome Coronavirus (MERS-CoV) drug discovery Expert Opin. Drug Discovery, 18: 385-400.
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  18. Badshah, I., N.G. Qazi, F. Ali, A.M. Minhas and A.M. Alvi et al., 2023. Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway. PLoS ONE, Vol. 18. 10.1371/journal.pone.0287517.
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  19. Al-Mubarak, A.I.A., J. Hussen, M. Kandeel, A.A.G. Al-Kubati, B. Falemban and M.G. Hemida, 2023. Evidence of the circulation of avian metapneumovirus in domestic backyard chickens in Eastern Saudi Arabia in 2019. Vet. World, 16: 1246-1251.
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  20. Al-Mubarak, A.I.A., J. Hussen, M. Kandee, A.A.G. Al-Kubati and B. Falemban, 2023. Avian encephalomyelitis virus in backyard chickens. Vet. World, 16: 1866-1870.
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  21. Al-Mubarak, A.I.A., A.A.G. Al-Kubati, A. Skeikh, J. Hussen, M. Kandeel, B. Flemban and M.G. Hemida, 2023. A longitudinal study of bovine viral diarrhea virus in a semi-closed management dairy cattle herd, 2020-2022. Front. Vet. Sci., Vol. 10. 10.3389/fvets.2023.1221883.
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  22. Al-Hetty, H.R.A.K., A.T. Jalil, J.H.Z. Al-Tamimi, H.G. Shakier, M. Kandeel, M.M. Saleh and M. Naderifar, 2023. Engineering and surface modification of carbon quantum dots for cancer bioimaging. Inorg. Chem. Commun., Vol. 149. 10.1016/j.inoche.2023.110433.
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  23. Abd El-Lateef, H.M., M.M. Khalaf, M. Kandeel, A.A. Amer, A.A. Abdelhamid and A. Abdou, 2023. Designing, characterization, biological, DFT, and molecular docking analysis for new FeAZD, NiAZD, and CuAZD complexes incorporating 1-(2-hydroxyphenylazo)-2-naphthol (H2AZD). Comput. Biol. Chem., Vol. 105. 10.1016/j.compbiolchem.2023.107908.
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  24. Marzok, M., A.I. Almubarak, M. Kandeel, W. El-Deeb, H. Babiker and S.F. El-Hawari, 2022. A randomized crossover study of the effect of butorphanol-lidocaine and tramadol-lidocaine on sevoflurane's minimum alveolar concentration in dogs. Front. Vet. Sci., Vol. 9. 10.3389/fvets.2022.1057580.
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  25. Kandeel, M. and Y. Kitade, 2011. The substrate binding preferences of Plasmodium thymidylate kinase. Biol. Pharm. Bull., 34: 173-176.
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  26. Kandeel, M. and Y. Kitade, 2010. Substrate specificity and nucleotides binding properties of NM23H2/nucleoside diphosphate kinase homolog from Plasmodium falciparum. J. Bioenergetics Biomembr., 42: 361-369.
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  27. Kandeel, M. and Y. Kitade, 2010. Binding dynamics and energetic insight into the molecular forces driving nucleotide binding by guanylate kinase. J. Mol. Recognit., 24: 322-332.
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  28. Kandeel, M., Y. Kitamura and Y. Kitade, 2009. The exceptional properties of Plasmodium deoxyguanylate pathways as a potential area for metabolic and drug discovery studies. Nucleic Acids Symp. Ser., 53: 39-40.
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  29. Kandeel, M., T. Miyamoto and Y. Kitade, 2009. Bioinformatics, enzymologic properties and comprehensive tracking of Plasmodium falciparum nucleoside diphosphate kinase. Biol. Pharm. Bull., 32: 1321-1327.
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  30. Kandeel, M., T. Ando, Y. Kitamura, M. Abdel-Aziz and Y. Kitade, 2009. Mutational, inhibitory and microcalorimetric analyses of Plasmodium falciparum TMP kinase. Implications for drug discovery. Parasitology, 136: 11-25.
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  31. Kandeel, M., A. Kato and Y. Kitade, 2009. Thymidylate kinase: The lost chemotherapeutic target. Nucleic Acids Symp. Ser. (Oxf.), 53: 283-284.
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  32. Kandeel, M., M. Nakanishi, T. Ando, K. El-Shazly, T. Yosef, Y. Ueno and Y. Kitade, 2008. Molecular cloning, expression, characterization and mutation of Plasmodium falciparum guanylate kinase. Mol. Biochem. Parasitol., 159: 130-133.
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  33. Kandeel, M. and Y. Kitade, 2008. Molecular characterization, heterologous expression and kinetic analysis of recombinant Plasmodium falciparum thymidylate kinase. J. Biochem., 144: 245-250.
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  34. Ando, T., H. Shinohara, X. Luo, M. Kandeel and Y. Kitade, 2007. Facile synthesis of 1',2'-cis-beta-pyranosyladenine nucleosides. Carbohydr. Res., 342: 2641-2648.
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