Prof. Dr. Mohamed Hamed Mohamed Al-Agamy
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Prof. Dr. Mohamed Hamed Mohamed Al-Agamy

Professor
King Khalid University, Saudi Arabia


Highest Degree
Ph.D. in Microbiology and Immunology from Al-Azhar University, Egypt

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Area of Interest:

Molecular Sciences
100%
Infectious Diseases
62%
Chemotherapy
90%
Immunology
75%
Microbiology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Samaha, H.A., M.H. Al-Agamy and W.E. Soliman, 2017. Antibiotic effect on planktonic and biofilm-producing staphylococci. Microbiology, 7: 498-512.
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  2. Radwan, A.A., F.K. Alanazi and M.H. Al-Agamy, 2017. 1,3,4-Thiadiazole and 1,2,4-triazole-3(4H)-thione bearing salicylate moiety: Synthesis and evaluation as anti-Candida albicans. Braz. J. Pharmaceut. Sci., Vol. 53, No. 1. 10.1590/s2175-97902017000115239.
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  3. Ghaith, D.M., M.M. Zafer, M.H. Al-Agamy, E.J. Alyamani, R.Y. Booq and O. Almoazzamy, 2017. The emergence of a novel sequence type of MDR Acinetobacter baumannii from the intensive care unit of an Egyptian tertiary care hospital. Ann. Clin. Microbiol. Antimicrob., Vol. 16. 10.1186/s12941-017-0208-y.
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  4. El-Mahdy, T.S., M.H. Al-Agamy, A.A. Al-Qahtani and A.M. Shibl, 2017. Detection of blaOXA-23-like and blaNDM-1 in Acinetobacter baumannii from the Eastern region, Saudi Arabia. Microb. Drug Resistance, 23: 115-121.
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  5. Alam, M.A., F.I. Al-Janoobi, K.A. Alzahrani, M.H. Al-Agamy, A.A. Abdelgalil and A.M. Al-Mohizea, 2017. In-vitro efficacies of topical microemulsions of clotrimazole and ketoconazole and in-vivo performance of clotrimazole microemulsion. J. Drug Deliv. Sci. Technol., 39: 408-416.
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  6. Al-Wabli, R.I., A.R. Al-Ghamdi, H.A. Ghabbour, M.H. Al-Agamy, J.C. Monicka, I.H. Joe and M.I. Attia, 2017. Synthesis, X-ray single crystal structure, molecular docking and DFT computations on N-[(1E)-1-(2H-1,3-benzodioxol-5-yl)-3-(1H-imidazol-1-yl)propylidene]-hydroxylamine: A new potential antifungal agent precursor. Molecules, Vol. 22. 10.3390/molecules22030373.
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  7. Al-Agamy, M.H., K. Jeannot, T.S. El-Mahdy, A.M. Shibl, W. Kattan, P. Plesiat and P. Courvalin, 2017. First detection of GES-5 carbapenemase-producing Acinetobacter baumannii isolate. Microb. Drug Resistance, 23: 556-562.
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  8. Al-Agamy, M.H., A. Aljallal, H.H. Radwan and A.M. Shibl, 2017. Characterization of carbapenemases, ESBLs and plasmid-mediated quinolone determinants in carbapenem-insensitive Escherichia coli and Klebsiella pneumoniae in Riyadh hospitals. J. Infect. Public Health, (In Press). 10.1016/j.jiph.2017.03.010.
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  9. Elshaier, Y.A., A. Barakat, B.M. Al-Qahtany, A.M. Al-Majid and M.H. Al-Agamy, 2016. Synthesis of pyrazole-thiobarbituric acid derivatives: Antimicrobial activity and docking studies. Molecules, Vol. 21. 10.3390/molecules21101337.
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  10. El-Kersh, T.A., M.A. Marie, Y.A. Al-Sheikh, M.H. Al-Agamy and A.A. Al-Bloushy, 2016. Prevalence and risk factors of early fecal carriage of Enterococcus faecalis and Staphylococcus spp and their antimicrobial resistant patterns among healthy neonates born in a hospital setting in central Saudi Arabia. Saudi Med. J., 37: 280-287.
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  11. Barakat, A., B.M. Al-Qahtani, A.M. Al-Majid, M. Ali, M.R. Shaik, M.H.M. Al-Agamy and A. Wadood, 2016. Synthesis, characterization, antimicrobial activity and molecular docking studies of combined pyrazol-barbituric acid pharmacophores. Trop. J. Pharmaceut. Res., 15: 2197-2207.
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  12. Alanazi, A.M., A.A.M. Abdel-Aziz, T.Z. Shawer, R.R. Ayyad and A.M. Al-Obaid et al., 2016. Synthesis, antitumor and antimicrobial activity of some new 6-methyl-3-phenyl-4(3H)-quinazolinone analogues: In silico studies. J. Enzyme Inhibit. Med. Chem., 31: 721-735.
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  13. Al-Agamy, M.H., T.S. El Mahdy and A.M. Shibl, 2016. Fecal colonization with extended-spectrum beta-lactamase and AmpC-producing Escherichia coli. BioMed Res. Int. 10.1155/2016/3704150.
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  14. Al-Agamy, M.H., K. Jeannot, T.S. El-Mahdy, H.A. Samaha, A.M. Shibl, P. Plesiat and P. Courvalin, 2016. Diversity of molecular mechanisms conferring carbapenem resistance to Pseudomonas aeruginosa isolates from Saudi Arabia. Can. J. Infect. Dis. Med. Microbiol. 10.1155/2016/4379686.
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  15. Al Majid, A.M.A., A. Barakat, Y.N. Mabkhot and M.H.M. Al-Agamy, 2016. Synthesis and characterization of a new series of sulfite and sulfate derivatives of D-Mannitol. J. Saudi Chem. Soc., 20: 307-312.
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  16. Ahmed, S., M.F. Zayed, S.M. El-Messery, M.H. Al-Agamy and H.M. Abdel-Rahman, 2016. Design, synthesis, antimicrobial evaluation and molecular modeling study of 1,2,4-triazole-based 4-thiazolidinones. Molecules, Vol. 21. 10.3390/molecules21050568.
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  17. Zafer, M.M., M.H. Al-Agamy, H.A. El-Mahallawy, M.A. Amin and S.E.D. Ashour, 2015. Dissemination of VIM-2 producing Pseudomonas aeruginosa ST233 at tertiary care hospitals in Egypt. BMC Infect. Dis., Vol. 15. 10.1186/s12879-015-0861-8.
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  18. Lopes, B.S., M.H. Al-Agamy, M.A. Ismail, A.M. Shibl, A.A. Al-Qahtani, M.N. Al-Ahdal and K.J. Forbes, 2015. The transferability of blaOXA-23 gene in multidrug-resistant Acinetobacter baumannii isolates from Saudi Arabia and Egypt. Int. J. Med. Microbiol., 305: 581-588.
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  19. Elkersh, T., M.A. Marie, Y.A. Al-Sheikh, A.A. AlBloushy and M.H. Al-Agamy, 2015. Prevalence of fecal carriage of extended-spectrum- and metallo-β-lactamase-producing gram-negative bacteria among neonates born in a hospital setting in Central Saudi Arabia. Ann. Saudi Med., 35: 240-247.
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  20. Barakat, A., H.J. Al-Najjar, A.M. Al-Majid, S.M. Soliman and Y.N. Mabkhot et al., 2015. Synthesis, molecular structure investigations and antimicrobial activity of 2-thioxothiazolidin-4-one derivatives. J. Mol. Struct., 1081: 519-529.
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  21. Al-Obeid, S., L. Jabri, M. Al-Agamy, A. Al-Omari and A. Shibl, 2015. Epidemiology of extensive drug resistant Acinetobacter baumannii (XDRAB) at Security Forces Hospital (SFH) in Kingdom of Saudi Arabia (KSA). J. Chemother., 27: 156-162.
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  22. Abdelmegid, F., M. Al-Agamy, A. Alwohaibi, H. Ka'abi and F. Salama, 2015. Effect of honey and green tea solutions on Streptococcus mutans. J. Clin. Pediatr. Dentistry, 39: 435-441.
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  23. Zafer, M.M., M.H. Al-Agamy, H.A. El-Mahallawy, M.A. Amin and M.S.E.D. Ashour, 2014. Antimicrobial resistance pattern and their beta-lactamase encoding genes among Pseudomonas aeruginosa strains isolated from cancer patients. BioMed Res. Int. 10.1155/2014/101635.
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  24. Zafer, M.M., M. Amin, H. El Mahallawy, M.S.E.D. Ashour and M. Al Agamy, 2014. First report of NDM-1-producing Pseudomonas aeruginosa in Egypt. Int. J. Infect. Dis., 29: 80-81.
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  25. Barakat, A., A.M. Al-Majid, F.M. Al-Qahatany, M.S. Islam and M.H. Al-Agamy, 2014. Synthesis, characterization and antimicrobial activity of novel pharmacophores incorporating imidazoline-oxazoline scaffold. Bull. Korean Chem. Soc., 35: 563-568.
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  26. Al-Qahtani, A.A., M.H. Al-Agamy, M.S. Ali, M.N. Al-Ahdal, M.A. Aljohi and A.M. Shibl, 2014. Characterization of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae from Riyadh, Saudi Arabia. J. Chemother., 26: 139-145.
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  27. Al-Agamy, M.H., N.G. Khalaf, M.M. Tawfick, A.M. Shibl and A. El Kholy, 2014. Molecular characterization of carbapenem-insensitive Acinetobacter baumannii in Egypt. Int. J. Infect. Dis., 22: 49-54.
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  28. Al-Agamy, M.H., A.M. Shibl, M.S. Ali, H. Khubnani, H.H. Radwan and D.M. Livermore, 2014. Distribution of β-lactamases in carbapenem-non-susceptible Acinetobacter baumannii in Riyadh, Saudi Arabia. J. Global Antimicrob. Resistance, 2: 17-21.
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  29. Al-Agamy, M.H., A.M. Shibl, M.M. Hafez, M.N. Al-Ahdal, Z.A. Memish and H. Khubnani, 2014. Molecular characteristics of extended-spectrum β-lactamase-producing Escherichia coli in Riyadh: Emergence of CTX-M-15-producing E. coli ST131. Ann. Clin. Microbiol. Antimicrob., Vol. 13. 10.1186/1476-0711-13-4.
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  30. Al-Agamy, M.H., 2014. Pattern and determinants of antimicrobial resistance in uropathogenic extended spectrum β-lactamase producing Escherichia coli. J. Pure Applied Microbiol., 8: 2325-2335.
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  31. Al Majid, A.M.A., I.M. Shahidul, A. Barakat, M.H.M. Al-Agamy and M. Naushad, 2014. Facile and promising method for Michael addition of indole and pyrrole to electron deficient trans-β-nitroolefins catalyzed by a hydrogen bond donor catalyst Feist’s acid: And Preliminary study of anti-microbial activity. Sci. World J., Vol. 2014. 10.1155/2014/649197.
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  32. Al Jameel, M., M.H. Al-Agamy, I. Aljufalli and A.M. Shibl, 2014. Antimicrobial Susceptibility and Distribution of β-lactamases in extended-spectrum cephalosporins insensitive Klebsiella pneumoniae in Riyadh, Saudi Arabia. J. Pure Applied Microbiol., 8: 2713-2720.
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  33. Shibl, A., M. Al-Agamy, Z. Memish, A. Senok, S.A. Khader and A. Assiri, 2013. The emergence of OXA-48-and NDM-1-positive Klebsiella pneumoniae in Riyadh, Saudi Arabia. Int. J. Infect. Dis., 17: e1130-e1133.
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  34. Al-Agamy, M.H., A.M. Shibl, N.A. Elkhizzi, D. Meunier, J.F. Turton and D.M. Livermore, 2013. Persistence of Klebsiella pneumoniae clones with OXA-48 or NDM carbapenemases causing bacteraemias in a Riyadh hospital. Diagnostic Microbiol. Infect. Dis., 76: 214-216.
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  35. Al-Agamy, M.H., 2013. Phenotypic and molecular characterization of extended-spectrum β-lactamases and AmpC β-lactamases in Klebsiella pneumoniae. Pak. J. Pharm. Sci., 26: 291-298.
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  36. Tawfik, A.F., A.M. Shibl, M.A. Aljohi, M.A. Altammami and M.H. Al-Agamy, 2012. Distribution of Ambler class A, B and D β-lactamases among Pseudomonas aeruginosa isolates. Burns, 38: 855-860.
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  37. Shibl, A.M., M.H. Al-Agamy, H. Khubnani, A.C. Senok, A.F. Tawfik and D.M. Livermore, 2012. High prevalence of acquired quinolone-resistance genes among Enterobacteriaceae from Saudi Arabia with CTX-M-15 β-lactamase. Diagnostic Microbiol. Infect. Dis., 73: 350-353.
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  38. Al-Agamy, M.H.M., A.M. Shibl and H.H. Radwan, 2012. Detection of mutations in quinolone-resistant determining regions in clinical isolates of Escherichia coli from Saudi Arabia. Afr. J Biotechnol., 11: 1054-1058.
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  39. Al-Agamy, M.H.M., 2012. Molecular resistance mechanisms to older antimicrobial agents in Eschericia coli isolates. Afr. J. Microbiol. Res., 6: 106-111.
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  40. Al-Agamy, M.H., A.M. Shibl, A.F. Tawfik, N.A. Elkhizzi and D.M. Livermore, 2012. Extended-spectrum and metallo-beta-lactamases among ceftazidime-resistant Pseudomonas aeruginosa in Riyadh, Saudi Arabia. J. Chemotherapy, 24: 97-100.
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  41. Al-Agamy, M.H., 2012. Genetic basis of cefotaxime resistant isolates of Klebsiella pneumoniae from Cairo. Afr. J. Microbiol. Res., 6: 20-27.
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  42. Al-Agamy, M.H. and S.A. Zaki, 2012. Mechanisms of fluoroquinolones resistance in Escherichia coli isolates from Saudi Arabia. Afr. J. Microbiol. Res., 6: 155-159.
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  43. Tawfik, A.F., A.M. Alswailem, A.M. Shibl and M.H. Al-Agamy, 2011. Prevalence and genetic characteristics of TEM, SHV and CTX-M in clinical Klebsiella pneumoniae isolates from Saudi Arabia. Microbial Drug Resist., 17: 383-388.
    PubMed  |  Direct Link  |  
  44. Al-Agamy, M.H., A.M. Shibl, S.A. Zaki and A.F. Tawfik, 2011. Antimicrobial resistance pattern and prevalence of metallo-β-lactamases in Pseudomonas aeruginosa from Saudi Arabia. Afr. J. Microbiol. Res., 5: 5528-5533.
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  45. Al-Agamy, M.H., 2011. Review: Tools of biological warfare. Res. J. Microbiol., 6: 193-245.
  46. Abdel-Aziz, A.A.M., Y.A. Asiri and M.H.M. Al-Agamy, 2011. Design, synthesis and antibacterial activity of fluoroquinolones containing bulky arenesulfonyl fragment: 2D-QSAR and docking study. Eur. J. Med. Chem., 46: 5487-5497.
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  47. Mahmoud, M.A., M.H. Al-Agamy, S.S. El-Loboudy and M.S. Ashour, 2009. Purification and characterization of neutral protease from Bacillus subtilis strain. N. Egypt. J. Microbiol., 22: 131-143.
  48. Al-Agamy, M.H., A.M. Shibl, A.K.F. Tawfic and A.R. Elbannai, 2009. Klebsiella pneumoniae producing CTX-M-15 from neonatal intensive care unit in Saudi Arabia. Res. J. Microbiol., 4: 278-285.
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  49. Al-Agamy, M.H., A.K.F. Tawfic, H.H. Radwan and A.M. Shibl, 2009. High prevalence of metallo-beta-lactamases in Pseudomonas aeruginosa from Riyadh, Saudi Arabia. J. Chemotherapy, 21: 461-462.
  50. Al-Agamy, M.H., A.K.F. Tawfic and A.M. Shibl, 2009. Prevalence and molecular characterization of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in Riyadh, Saudi Arabia. Ann. Saudi Med., 29: 253-257.
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  51. Al-Agamy, M.H., A.K.F. Tawfic and A.M. Shibl, 2009. Prevalence and characterization of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in Saudi Arabia. Egypt. J. Biomed. Sci., 29: 202-211.
  52. Al-Agamy, M.H., 2009. Pseudomonas aeruginosa clinical isolates producing metallo-B-lactamases VIM in Saudi Arabia. Egypt. J. Biomed. Sci., 29: 185-195.
  53. Al-Agamy, M.H., M.S. Ali, M.M. Salem and T.R. Mohamed, 2008. Faecal colonization by extended-spectrum beta-lactamase-producing Escherichia coli from hospitalized patients. N. Egypt. J. Microbiol., 19: 285-314.
  54. Ashour, M.S., S.S. El-Loboudy, M.H. Al-Agamy and M.A. Mahmoud, 2007. Production and properties of an extra-cellular protease from Bacillus species. N. Egypt. J. Microbiol., 18: 267-284.
  55. Al-Agamy, M.H., I. Wiegand, B. Wiedemann, M.S.E. Ashour, A.S.A.H. Helal and K.A. El-Ghareeb, 2007. Detection of mutations in gyrA and parC genes in quinolone-resistant clinical isolates of Escherichia coli. N. Egypt. J. Microbiol., 18: 98-108.
  56. Al-Agamy, M.H., M.S.E. Ashour and I. Wiegand, 2006. First description of CTX-M genes from Egyptian escherichia coli strains. Int. J. Antimicrob Agents, 27: 545-548.
  57. Al-Agamy, M.H., I. Wiegand, B. Wiedemann, M.S.E. Ashour, A.S.A.H. Helal and El-Ghareeb, 2006. Characterization of molecular resistance mechanisms to chloramphenicol in extended spectrum β-lactamase-producing Escherichia coli strains. N. Egypt. J. Microbiol., 14: 233-246.
  58. Al-Agamy, M.H., 2006. Detection of chloramphenicol resistance genes in broad spectrum β lactamase-producing Escherichia coli strains. N. Egypt. J. Microbiol., 13: 17-28.
  59. Wiegand, I., K. Noha, M.H. Al-Agamy and B. Wiedeman, 2004. First detection of transferable quinolone resistance determinant in clinical Providencia stuartti strains in Egypt. Clin. Microbiol. Infect., Vol. 10. .
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  60. Al-Agamy, M.H., H.M. Hefny, S.I. Fouda, M.S.M. Mansy and M.S.E. Ashour, 1999. Studies on microbial urinary tract infections in diabetic patients. Az. J. Microbiol., 44: 107-121.