Dr. Abdel-Hamid Zaki Abdel-Hamid Amer
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Dr. Abdel-Hamid Zaki Abdel-Hamid Amer

Professor Emeritus
National Research Centre, Egypt


Highest Degree
Ph.D. in Biochemistry from Ain Shams University, Egypt

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Area of Interest:

Biomedical Sciences
100%
Molecular Genetics
62%
Biochemistry
90%
Metabolomics
75%
Pharmacology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
71
Abstracts
0

Selected Publications

  1. Kamel, N.N., M.Z. Rizk, W.G. Hozayen and A.H.Z. Abdel-Hamid, 2019. ZnO nanoparticles: Crosslink between cytotoxicity on liver cell lines and in vivo biosafety on different mice organs. J. Applied Pharm. Sci., 9: 58-66.
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  2. Hussein, N.S., A.S. Helmy, N.M. Sherif, H.Z. Ghanem, N.A. Ibrahim, A.N.G. El Gendy and A.H.Z. Abdel-Hamid, 2019. Lipidomic analysis reveals the efficiency of Eclipta prostrate on diet-induced nonalcoholic fatty liver disease in rats. J. Pharm. Biomed. Anal., 165: 224-232.
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  3. Helmy, A.S., N.M. Sherif, H.Z. Ghanem, N.A. Ibrahim, A.N.G. El Gendy, N.S. Hussein and A.H.Z. Abdel-Hamid, 2019. Targeted metabolomics reveals the therapeutic impact of Eclipta prostrate on diet-induced non-alcoholic fatty liver disease in rats. J. Applied Pharm. Sci., 9: 77-90.
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  4. Abdel-Megeed, R.M., M.O. Kadry, D.B. Fayed and A.H.Z. Abdel-Hamid, 2019. Antimicrobial activity and acetylcholinestrase inhibition of novel synthesized pyrimidine derivatives versus Candida albicans trafficking to brain and kidney. Toxicol. Rep., 6: 262-266.
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  5. Abdel-Megeed, R.M., A.R. Hamed, A.A. Matloub, M.O. Kadry and A.H.Z. Abdel-Hamid, 2019. Regulation of apoptotic and inflammatory signaling pathways in hepatocellular carcinoma via Caesalpinia gilliesii galactomannan. Mol. Cell. Biochem., 451: 173-184.
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  6. Kadry, M.O., R.M. Abdel-Megeed, E. El-Meliegy and A.H.Z. Abdel-Hamid, 2018. Crosstalk between GSK-3, c-Fos, NFκB and TNF-α signaling pathways play an ambitious role in Chitosan nanoparticles cancer therapy. Toxicol. Rep., 5: 723-727.
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  7. Hussein, N.S., N.M. Sherif, A.S. Helmy, H.Z. Ghanem, N.A. Ibrahim, A.N.G. Ei-Gendy and A.H.Z. Abdel-Hamid, 2018. Targeted metabolomics for NAFLD: Early detection and therapeutic efficacy of Eclipta prostrate in rats. Biosci. Res., 15: 3545-3567.
  8. Shahfiza, N., H. Osman, T.T. Hock and A.H.Z. Abdel-Hamid, 2017. Metabolomics approach for multibiomarkers determination to investigate dengue virus infection in human patients. Acta Biochem. Pol., 64: 1-5.
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  9. Farag, M.A., N.M. Ammar, T.E. Kholeif, N.S. Metwally, N.M. El-Sheikh, L.A. Wessjohannd and A.Z. Abdel-Hamid, 2017. Rats’ urinary metabolomes reveal the potential roles of functional foods and exercise in obesity management. Food Funct., 8: 985-996.
  10. Ammara, N.M., M.A. Faragb, T.E. Kholeifc, N.S. Metwallya, N.M. El-Sheikhc, A.N. El Gendyd and A.H.Z. Abdel-Hamid, 2017. Serum metabolomics reveals the mechanistic role of functional foods and exercise for obesity management in rats. J. Pharm. Biomed. Anal., 142: 91-101.
  11. Abdel Megeeda, R.M., H.Z. Ghanema, M.M. Kamela, M.F. Bakeetb and A.H.Z. Abdel-Hamid, 2017. Assessment of some synthesized novel 9-substituted tetrahydroacridine derivatives in diabetic disease management in rats. Egypt. Pharm. J., 16: 53-61.
  12. Abd-Ellatef, G.E.F., O.M. Ahmed, E.S. Abdel-Reheim and A.H.Z. Abdel-Hamid, 2017. Ulva lactuca polysaccharides prevent Wistar rat breast carcinogenesis through the augmentation of apoptosis, enhancement of antioxidant defense system and suppression of inflammation. Breast Cancer, 9: 67-83.
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  13. Shaker, O.G., N.A.H. Sadik, H.Z. Ghanem, H.A. Hassan and A.Z. Abdel-Hamid, 2015. Single-nucleotide polymorphism of toll like receptor 4 in response to interferon based therapy in chronic HCV Egyptian patients. Arch. Virol., 160: 2181-2195.
  14. Shahfiza, N., Maulidiani, H. Osman, T.T. Hock, K. Shaari, B. Ibrahim and A.H.Z. Abdel-Hamid, 2015. Discrimination of dengue disease from healthy based on the chemometry of 1h nuclear magnetic resonance spectroscopy. J. Teknologi, 77: 27-32.
  15. Shahfiza, N., H. Osman, T.T. Hock, K. Shaan and A.H.Z. Abdel-Hamid, 2015. Metabolomics for characterization of gender differences in patients infected with dengue virus. Asian Pac. J. Trop. Med., 8: 268-268.
  16. Akram, A., T.H. Tang, B.S. Ang, R. Shaheen and A.H. Zaki, 2015. Perception of a new design of Toothbrush by its users. IOSR J. Dent. Med. Sci., 14: 58-61.
  17. Rizk, M.Z., W.K.B. Khalil, A.H.Z. Abdel-Hamid, S.H. Haggag, M.A. Hamed, M.B. Ahmed and N.N. Kamel, 2013. Molecular approach for detection compatibility/incompatibility of Egyptian Biomphalaria alexandrina and Bulinus truncates snails with their Miracidia. Int. J. Pharm. Clin. Res., 5: 96-104.
  18. Koriem, K.M.M., A.Z. Abdel-Hamid and H.F. Younes, 2013. Caffeic acid protects tissue antioxidants and DNA content in methamphetamine induced tissue toxicity in Sprague Dawley rats. Toxicol. Mech. Methods, 23: 134-143.
  19. Al-Salahi, O.S.A., A.H. Zaki, K.L. Chan, A.M. Shah, F. Al-Hassan, W.Z. Abdullah and N.M. Yusoff, 2013. In vitro anti-proliferative and apoptotic activities of Eurycoma longifolia Jack (Simaroubaceae) on HL-60 cell line. Trop. J. Pharm. Res., 12: 57-61.
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  20. Al-Salahi, O.S.A., A.H. Zaki, K.L. Chan, A.M. Shah, F. Al-Hassan, W.Z. Abdullah and N.M. Yusoff, 2012. The effect of Eurycoma longifolia root methanolic extract on gamma globin gene expression “In vitro study”. Biohealth Sci. Bull., 4: 8-12.
  21. Al-Salahi, O.S.A., A.H. Zaki, K.L. Chan, A.M. Shah, F. Al-Hassan, W.Z. Abdullah and N.M. Yusoff, 2012. The effect of Eurycoma longifolia root methanolic extract on gamma globin gene expression “In vitro study”. Biohealth Sci. Bull., 4: 14-17.
  22. Abdel Hamid, A.Z. and Y.A. Qunq, 2012. ABO blood group associations with obesity in random samples from advanced medical and dental institute staff and students. Biohealth Sci. Bull., 4: 18-23.
  23. Metwally, N.S., T.E. Kholeif, K.Z. Ghanem, A.R.H. Farrag, N.M. Ammar and A.H.Z. Abdel-Hamid, 2011. The protective effects of fish oil and artichoke on hepatocellular carcinoma in rats. Eur. Rev. Med. Pharmacol. Sci., 15: 1429-1444.
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  24. Akram, A., A.H. Hamid, J. Razak and T.T. Hock, 2011. MICAP-a novel system for identification and communication of dental problems. Int Dent. J., 61: 31-36.
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  25. Oliveira, A.L.D., D. da Silva, B.C. Manzano, A.Z. Abdel-Hamid and M.Y. Marcelino et al., 2010. Genetic differences between strains of Biomphalaria glabrata (Planorbidae) that are susceptible and unsusceptible to schistosomiasis. Genet. Mol. Res., 9: 1450-1459.
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  26. Bahari, M., N.M. Yusoff, F. Abd Karim, H. Hashim and A.Z. Abdel-Hamid, 2010. The study of platelet activation in platelet concentrates prepared by four types of apheresis machines. Biohealth Sci. Bull., 2: 25-31.
  27. Alshaban, Z.O., A.Z. Abdel-Hamid, T.T Hock and R. Hassan, 2010. Comparison between RT-PCR and ELISA for the detection of HBV in blood donors. Biohealth Sci. Bull., 2: 5-7.
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  28. Al-Alimi, A.A., N. Kanakiri, M. Kamil, H.S. Al-Rimawi, A.H. Zaki and N.M. Yusoff, 2010. Mediterranean glucose-6-phosphate dehydrogenase (G6PDC563T) mutation among Jordanian females with acute hemolytic crisis. J. Coll. Physicians Surg. Pak., 20: 794-797.
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  29. Zinab, O.A., T.T. Hock, A.Z. Abdel Hamid and R. Hassan, 2009. Significance of RT-PCR over ELISA technique for the detection of HCV in blood donor. Bioh. Sci. Bull., 1: 53-56.
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  30. Rizk, M., A.Z. Abdel-Hamid, E.T. Mamlouk and N. Said, 2009. Vertebrate-type steroids during maturation and infection of Biomphalaria alexandrina snails, the intermediate host of Schistosoma mansoni. Bioh. Sci. Bull., 1: 24-30.
  31. Akram, A., A.Z. Abdel Hamid, S.C. Joshi, B.A. Abdul Hameed and I. Pant, 2009. Radiotherapy complications and preventive measures in oral cancer. J. Ar. Soc. Med. Res., 4: 223-230.
  32. Abdel-Hamid, A.Z., F. El-Sharkawi, H. Zaki, K. Koriem, O. Badary, S.A. Hassan and H.A. Hassan, 2009. Antiangiogenic effect of C. sempervirens, C. majus and T. majus against hepatocellular carcinoma (HCC). Bioh. Sci. Bull., 1: 1-10.
  33. Oliveira, A.L.D., D. da Silva, E.M. Zanotti-Magalhaes, A.Z. Abdel-Hamid and J.T. Ribeiro-Paes, 2008. Schistosome/mollusk: Genetic compatibility. Genet. Mol. Res., 7: 518-526.
  34. Abdel Hamid, A.Z., S.M. Abd El-Wahab, M.M. Eltonsy and R.M. Abdel-Megeed, 2007. Molecular genetic variations among adjacent populations of freshwater snails that are target and non-target to Schistosoma infection. Egypt. J. Aquat. Biol. Fish., 11: 23-51.
  35. Abdel Hamid, A.Z., S.M. Abd El-Wahab, M.M. Eltonsy and R.M. Abdel-Megeed, 2007. Effect of some environmental parameters on crossing process of target snails to Schistosoma mansoni infection. Egypt. J. Aquat. Biol. Fish., 11: 1-21.
  36. Abdel-Hamid, A.Z., S. Rawy and A.F. Saad, 2006. Identification of the genetic marker associated with the resistance to Schistosoma mansoni infection using random amplified polymorphic DNA analysis. Mem. Inst. Oswaldo Cruz, 101: 863-868.
  37. Abdel Hamid, A.Z., S.M. Abd El-Wahab, M.M. Eltonsy and R.M. Abdel-Megeed, 2006. Biological studies on fresh water snails target to Schistosoma mansoni infection. Egypt. J. Hosp. Med., 24: 501-514.
  38. Abdel-Hamid, A.Z., M.Z. Rizk, T. El-Mamlouk and N.S. Metwally, 2005. Steroids in freshwater snails. Egypt. Pharm. J., 4: 153-165.
  39. Da Silva, D., S. Sobral-Hamaguchi, R.G.M. Spada, A.Z. Abdel-Hamid and N.R.B. Zuim et al., 2004. Biomphalaria tenagophila: Genetic variability between intermediate snail hosts susceptible and resistant to Schistosoma mansoni infection. Parasite, 11: 35-42.
  40. Spada, R.G.M., D. da Silva, A.Z. Abdel-Hamid, S. Sobral-Hamaguchi and N.R.B. Zuim et al., 2002. Genetic markers between Biomphalaria glabrata snails susceptible and resistant to Schistosoma mansoni infection. Mem. Inst. Oswald. Cruz, 97: 53-58.
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  41. Shalaby, N.M. and A.Z. Abdel-Hamid, 1999. Ammi majus L. extracts as potent molluscicides for control of B. alexandrina snails “specific intermediate hosts for S. mansoni”. Bull. N.R.C., 24: 153-170.
  42. Ahmed, K.M., A.M. Khattab, E.A.M. El-Khrisy and A.Z. Abdel-Hamid, 1999. Constituents and molluscicidal activity of the aerial parts of Acacia saligna, Chrysanthemum coronarium and Chrysanthemum parthenium. Bull. N.R.C., 24: 13-25.
  43. Abdel-Hamid, A.H.Z., J.B.D. Molfetta, V. Fernandez and V. Rodrigues, 1999. Genetic variation between susceptible and non-susceptible snails to Schistosoma infection using random amplified polymorphic DNA analysis (RAPDs). Rev. Inst. Med. Trop. S. Paulo, 41: 291-295.
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  44. Abdel-Hamid, A.Z. and M. Mantawy, 1998. Interrelationships between miracidia and the host snail Biomphalaria alexandrina: I- Amino acids as regulators of host and miracidia interaction. Egypt. J. Pharm. Sci., 39: 123-132.
  45. Abdel-Hamid A.Z. and S.M. Ali, 1998. Hirudo medicinalis as a potent agent for biological control of intermediate hosts of African Schistosome species. Egypt. J. Pharm. Sci., 39: 211-224.
  46. Abdel-Hamid, A.Z., 1997. Development of bait formulations for control of intermediate hosts of African schistosome species. J. Applied Toxicol., 17: 391-395.
  47. Abdel-Hamid, A.Z., 1997. Sesbania sesban and Peltophorum africanum as potent molluscicides of plant origin. Egypt. J. Bilh., 19: 115-128.
  48. Abdel-Hamid, A.Z. and M.Z. Rizk, 1997. High pressure liquid chromatographic analysis of DNA from different snail species, target and non-target to schistosoma infection. Egypt. J. Bilh., 19: 61-75.
  49. Abdel-Hamid, A.Z. and M.M.I. Mantawy, 1997. Effect of Frenkania hirsute and Withania somnifera on biological and physiological activities of Biomphalaria alexandrina snails. Egypt. J. Bilh., 19: 99-114.
  50. Nabih, I., A.M. Soliman and A.Z. Abdel-Hamid, 1996. Effect of aminopterine and methotrexate on nucleic acids and proteins of freshwater snails “Specific intermediate hosts for schistosomiasis”. J. Union Arab Biol., 5: 11-11.
  51. Aboul-Ela, E., A.Z. Abdel-Hamid and M.M.I. Mantawy, 1996. Effect of DDVP and sodium dihydrogen phosphate on chromosomal abberation of freshwater snails. Egypt. J. Pharm. Sci., 37: 48-59.
  52. Abdel-Hamid, A.Z., M.Z. Rizk, I. Nabih, S. Abdel-Hamid, N.M. Abdalla and M.M.I. Mantawy, 1996. Effect of some nitrogen and sulfur containing fertilizers on fatty acids, nucleic acids and proteins in the tissues of B. alexandrina snails susceptible to infection with Schistosoma mansoni. J. Union Arab Biol. Cairo, 5: 171-187.
  53. Abdel-Hamid, A.Z., E. Farrag, M.Z. Rizk, M.T. Omar and M.M.I. Mantawy, 1996. Effect of some nitrogen, sulfur and phosphorus containing fertilizers on egg laying of freshwater snails. Egypt. J. Pharm. Sci., 37: 21-34.
  54. Abdel-Hamid, A.Z., 1996. Chemo-attraction of Biomphalaria alexandrina snails “ intermediate hosts for Schistosoma mansoni” to different carbohydrates. Egypt. J. Bilh., 18: 39-54.
  55. Abdel-Hamid, A.Z., 1996. Behavioral responses to amino acids by Biomphalaria alexandrina snails “Intermediate host of S. mansoni”. Egypt. J. Bilh., 18: 13-26.
  56. Nabih, I., A.Z. Abdel-Hamid, N. Mahmoud and S.A. Hassan, 1994. Studies on the immunological effects of nucleoproteins isolated from different stages of B. alexandrina snails on schistosomiasis. Egypt. J. Pharm. Sci., 35: 39-49.
  57. Nabih, I., A.Z. Abdel-Hamid, N. Mahmoud and S.A. Hassan, 1994. Immunological effects of chemically modified nucleoproteins isolated from different stages of B. alexandrina snails on schistosomiasis. J. Biomed. Sci. Ther., 10: 72-82.
  58. Ahmed, S. and A.Z. Abdel-Hamid, 1994. An attempt toward combat of schistosomiasis: I-selected biochemical reactions of “Dursban” as a molluscicides on freshwater snails. J. Biomed. Sci. Ther., 10: 51-61.
  59. Abdel-Hamid, A.Z., M. Rizk and Z. El-Bazza, 1994. Effect of γ-irradiation on egg masses of Biomphalaria alexandrina snails. Egypt. J. Pharm. Sci., 35: 51-60.
  60. Nassar, M.I. and A.Z. Abdel-Hamid, 1993. Phytochemical and molluscicidal screening of some local plants. Bull. N.R.C. Egypt, 18: 335-341.
  61. Abdel-Hamid, A.Z., M. Rizk and L.H. Fadda, 1993. Effect of some newly synthesized purine analogues on nucleic acids in mice bearing parasitic infections. Egypt. J. Pharm. Sci., 34: 125-132.
  62. Abdel-Hamid, A.Z. and O.A. Fathalla, 1993. Studies on the effect of some uracil derivatives on mice bearing Ehrlich ascites carcinoma. Egypt. J. Pharm. Sci., 34: 67-80.
  63. Abdel-Hamid, A.Z., M. Rizk and S. Ahmed, 1992. Effect of some schistosomal proteins on worm production in mice infected with Schistosoma mansoni. J. Biomed. Sci. Ther., 8: 1-14.
  64. Ahmed, S. and A.Z. Abdel-Hamid, 1991. Biochemical studies on the effect of Alium sepa and Alium sativum on nucleic acid of Ehrlich ascites carcinoma. J. Biomed. Sci. Ther., 7: 1-9.
  65. Abdel-Hamid, A.Z., 1991. Effect of diets on Biomphalaria alexandrina snails “specific intermediate hosts for S. mansoni”. J. Biomed. Sci. Ther., 8: 1-12.
  66. Nabih, I., M.M. Mantawy and A.Z. Abdel-Hamid, 1990. Studies on the nucleic acid of human bladder carcinoma. Cell. Mol. Biol., 36: 299-308.
    PubMed  |  
  67. Nabih, I., A.Z. Abdel-Hamid, M.M. Kamel and W. Abdou, 1989. Effect of some pyrimidine antimetabolites on nucleic acid content in freshwater snails “specific intermediate hosts for schistosomiasis”. Egypt. J. Bilh., 11: 155-164.
  68. Nabih, I., A.M. Soliman and A.Z. Abdel-Hamid, 1989. Studies on freshwater snails, II-Isolation of haemoglobin from native and chemically treated snails. Cell. Mol. Biol., 35: 597-602.
  69. Nabih, I., A.M. Soliman and A.Z. Abdel-Hamid, 1989. Studies on fresh water snails, specific intermediate hosts for schistosomiasis. I: Isolation of total lipids from native and irradiated snails. Cell. Mol. Biol., 35: 373-377.
  70. Nabih, I. and A.Z. Abd El Hamid, 1984. Biochemical studies on the genetic material of fresh water snails, intermediate hosts of schistosomiasis. II: Effect of a chemical mutagen, cyclophosphamide, on the chemical nature of deoxyribonucleic acid. Cell. Mol. Biol., 30: 125-127.
  71. Nabih, I. and A.Z. Abd El Hamid, 1984. Biochemical studies on the genetic material of fresh water snails, intermediate hosts of schistosomiasis. I: Effect of ultraviolet radiation as physical mutagen on the chemical nature of deoxyribonucleic acid. Cell. Mol. Biol., 30: 33-36.