Prof. Dr. Mohamed El-Desouky Mohamed Zain

Prof. Dr. Mohamed El-Desouky Mohamed Zain

Professor
Al-Azhar University, Egypt


Highest Degree
Ph.D. in Microbiology from Al-Azhar University, Egypt

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Area of Interest:

Molecular Sciences
100%
Microbiology
62%
Molecular Biology
90%
Mycology
75%
Biotechnology
55%

Selected Publications

  1. Awaad, A.S., H.A. Al-Mudhayyif, M.R. Al-Othman, M.E. Zain and R.M. El-Meligy, 2017. Amhezole, a novel fungal secondary metabolite from Aspergillus terreus for treatment of microbial mouth infection. Phytother. Res., 31: 395-402.
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  2. Awaad, A.S., A.M. Alafeefy, F.A. Alasmary, R.M. El-Meligy, M.E. Zain and S.I. Alqasoumi, 2017. Novel essential amino acid-sulfanilamide hybrid as safe anti-ulcerogenic agent with anti-helicobacter pylori activity. Saudi Pharmaceut. J., 25: 967-971.
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  3. Awaad, A.S., M. Abdalqawi, S.A. Kenawi, M.R. Alothman, S. Rehab and M. Zain, 2016. Pharmacological activities for the extract and isolated compounds of Euphorbia cuneata Vhl. Int. J. Biol. Pharm. Allied Sci., 5: 319-331.
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  4. Awaad, A.S., A. Al-Refaie, R. El-Meligy, M. Zain, H. Soliman, M.S. Marzoke and N. El-Sayed, 2016. Novel compounds with new anti-ulcergenic activity from Convolvulus pilosellifolius using bio-guided fractionation. Phytother. Res., 30: 2060-2064.
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  5. El-Sakhawy, M.A., M.I. Al-Zaban, M.A. Alharbi, N.S. Abdelazim and M.E. Zain, 2015. Synergistic effect of medicinal plants and antibiotics on pathogenic bacteria. Int. J. Biol. Pharm. Allied Sci., 4: 5792-5800.
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  6. Awaad, A.S., A.A. Al‐Rifai, R.M. El‐Meligy, A.M. Alafeefy and M.E. Zain, 2015. New activities for isolated compounds from Convolvulus austro‐aegyptiacus as anti‐ulcerogenic, anti‐Helicobacter pylori and their mimic synthesis using bio‐guided fractionation. Phytotherapy Res., 29: 1311-1316.
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  7. Alasmary, F.A., A.M. Snelling, M.E. Zain, A.M. Alafeefy, A.S. Awaad and N. Karodia, 2015. Synthesis and evaluation of selected benzimidazole derivatives as potential antimicrobial agents. Molecules, 20: 15206-15223.
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  8. Alafeefy, A.M., A.S. Awaad, H.A. Abdel-Aziz, R.M. El-Meligy, M.E. Zain, M.R. Al-Outhman and A.B. Bacha, 2015. Synthesis and biological evaluation of certain 3-substituted benzylideneamino-2-(4-nitrophenyl) quinazolin-4(3H)-one derivatives. J. Enzyme Inhibit. Med. Chem., 30: 270-276.
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  9. Zain, M.E., A.S. Awaad, M.R. Al-Othman, A.M. Alafeefy and R.M. El-Meligy, 2014. Biological activity of fungal secondary metabolites. Int. J. Chem. Applied Biol. Sci., 1: 14-22.
  10. Zain, M.E., A.S. Awaad, M.R. Al Othman and S.K. Al-Dosary, 2014. Antibacterial, antifungal activity and phytochemical analysis of some desert plants against human pathogenic bacteria and fungi. Life Sci. J., 11: 343-349.
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  11. El-Meligy, R.M., M.E. Zain and F.A. Ahmed, 2014. Protective role of Cynanchum acutum L. extracts on carbon tetrachloride-induced hepatotoxicity in rat. Int. J., 1: 8-13.
  12. El-Meligy, R.M., A.S. Awaad, M.E. Zain, A.M. Alafeefy and S.A. Kenawy, 2014. Anti-inflammatory and antinociceptive activities of extracts and compounds isolated from Solenostemma arghel (Del.) Hayne. Int. J. Chem. Applied Biol. Sci., 1: 1-8.
  13. Awaad, A.S., T.A. Alhamed, D.J. Maitland, G.A. Soliman and N.A. Al-Jaber et al., 2014. Evaluation of the antimicrobial activity, sub-chronic toxicity and wound healing effect of Cunninghamella elegans extract and its isolated compounds. Life Sci. J., 11: 261-268.
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  14. Awaad, A.S., M.E. Zain, M.R. Al Othman and S.K. Al-Dosary, 2014. Phytochemical analysis and antimicrobial activity of medicinal plants against pathogenic microorganisms. Life Sci. J., 11: 350-354.
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  15. Alafeefy, A.M., S.I. Alqasoumi, S.G. Abdel Hamid, K.E.H. El-Tahir, M. Mohamed, M.E. Zain and A.S. Awaad, 2014. Synthesis and hypoglycemic activity of some new theophylline derivatives. J. Enzyme Inhibit. Med. Chem., 29: 443-448.
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  16. Zain, M.E., A.H. Bahkali and M.R. Al-Othman, 2013. Development of using fatty acids in fungal chemotaxonomy. Afr. J. Microbiol. Res., 7: 4638-4645.
  17. Zain, M.E. and M.R. Al-Othman, 2013. Physiological and morphological characteristics of phagesi infecting Bacillus thuringiensis isolated from Saudi Arabia soil. Aust. J. Basic Applied Sci., 7: 388-392.
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  18. El-Meligy, R.M., A.S. Awaad, M.E. Zain and A.M. Alafeefy, 2013. Evaluation of selected desert plants as anti-ulcerogenic natural products. Aust. J. Basic Applied Sci., 7: 431-436.
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  19. Awaad, A.S., R.M. El-Meligy, N.A. Al-Jaber, H.S. Al-Muteeri and M.E. Zain et al., 2013. Anti-ulcerative colitis activity of compounds from Euphorbia granuleta Forssk. Phytother. Res., 27: 1729-1734.
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  20. Awaad, A.S., N.A. Al-Jaber, J.E. Moses, R.M. El-Meligy and M.E. Zain, 2013. Antiulcerogenic activities of the extracts and isolated flavonoids of Euphorbia cuneata Vahl. Phytother. Res., 27: 126-130.
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  21. Zain, M.E., S.T. Moss and H.H. El-Sheikh, 2012. Development of merosporangia in Linderina pennispora (Kickxellales, Kickxellaceae). IMA Fungus, 3: 103-108.
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  22. Zain, M.E., A.S. Awaad, M.R. Al-Outhman and R.M. El-Meligy, 2012. Antimicrobial activities of Saudi Arabian desert plants. Phytopharmacology, 2: 106-113.
  23. Zain, M.E., A.H. Bahkali, M.R. Al-Othman and A.M. Khalil, 2012. Advantage of using secondary metabolites in fungal chemotaxonomy. Aust. J. Basic Applied Sci., 6: 95-103.
  24. Zain, M.E., A.H. Bahkali and M.R. Al-Othman, 2012. Effect of chemical compounds on amino acid content of some Fusarium species and its significance to fungal chemotaxonomy. J. Saudi Chem. Soc., 16: 183-192.
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  25. Awaad, A.S., N.A. Al-Jaber, G.A. Soliman, M.R. Al-Outhman, M.E. Zain, J.E. Moses and R.M. El-Meligy, 2012. New biological activities of Casimiroa edulis leaf extract and isolated compounds. Phytother. Res., 26: 452-457.
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  26. Awaad, A.S., A.J.A. Nabilah and M.E. Zain, 2012. New antifungal compounds from Aspergillus terreus isolated from desert soil. Phytother. Res., 26: 1872-1877.
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  27. Zain, M.E., H.H. El-Sheikh, H.G. Soliman and A.M. Khalil, 2011. Effect of certain chemical compounds on secondary metabolites of Penicillium janthinellum and P. duclauxii. J. Saudi Chem. Society, 15: 239-246.
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  28. Zain, M.E., 2011. Impact of mycotoxins on humans and animals. J. Saudi Chem. Soc., 15: 129-144.
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  29. Mattar, E.H., L.F. Hammad and M.E. Zain, 2011. Effect of cadmium, cobalt and chromium on growth of three Cunninghamella species. J. Saudi Chem. Society, 15: 357-359.
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  30. Zain, M.E., 2010. Biochemical markers in taxonomy of the genus Fusarium. Res. J. Agric. Biol. Sci., 6: 1-7.
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  31. Zain, M.E., H.M. Mahdy and M.A. Hemdan, 2009. Increasing susceptibility of clinical isolates of Candida species to azole antifungal drugs. J. Applied Sci. Res., 5: 1325-1334.
  32. Zain, M.E., A.S. Awaad, A.A. Razak, D.J. Maitland, N.E. Khamis and M.A. Sakhawy, 2009. Secondary metabolites of Aureobasidium pullulans isolated from Egyptian soil and their biological activity. J. Applied Sci. Res., 5: 1582-1591.
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  33. Zain, M.E., A.A. Razak, H.H. El-Sheikh, H.G. Soliman and A.M. Khalil, 2009. Influence of growth medium on diagnostic characters of Aspergillus and Penicillium species. Afr. J. Microbiol. Res., 3: 280-286.
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  34. Zain, M.E., A.A. Farrag and A.A. Abdel-Fattah, 2009. Effect of aflatoxins on ultrastructures of Geotrichum candidum. New Egypt. J. Microbiol., 22: 119-130.
  35. Zain, M.E., 2009. Effect of olive oil on secondary metabolite and fatty acid profiles of Penicillium expansum, Aspergillus flavus, A. parasiticus and A. ochraceus. Aust. J. Basic Applied Sci., 3: 4274-4280.
  36. Zain, M.E., H.M. Mahdy and M.A. Hemdan, 2007. Impact of medicinal plants on sensitivity of Candida strains to antifungal drugs. J. Biol. Chem. Environ. Sci., 2: 49-65.
  37. Zain, M.E., A.T. Abul-Hamd and H.M. Atta, 2004. Detection of genetic variation in Fusarium oxysporum isolates using RAPD analysis. New Egypt. J. Microbiol., 8: 348-359.
  38. Zain, M.E., 2004. Secondary metabolites as taxonomic markers in fungal taxonomy. Afr. J. Mycol. Biotechnol., 12: 45-54.
  39. Mahdy, H.M. and M.E. Zain, 2004. Bacteriological study on Nile water at certain localities at Cairo. New Egypt. J. Microbiol., 8: 213-223.
  40. Atta, H.M., M.E. Zain and A.T. Abul-Hamd, 2004. Production, physico-chemical properties and biological activities of an antibacterial agent produced by Streptomyces fradiae. Egypt. J. Biotechnol., 17: 410-428.
  41. Atta, H.M., A.T. Abul-Hamd and M.E. Zain, 2003. Fermentation, extraction, physiological properties and biological activities of the antifungal agent produced by Streptomyces aureofaciens. Afr. J. Mycol. Biotechnol., 11: 51-67.
  42. Moss, S.T., A.A. Razak, H.H. El-Sheikh and M.E. Zain, 2002. Ultrastructure of vegetative and reproductive structures of Kickxella alabastrina (Kickxellaceae, Zygomycetes). Afr. J. Mycol. Biotechnol., 10: 35-45.
  43. Moss, S.T., A.A. Razak, H.H. El-Sheikh and M.E. Zain, 2002. Ultrastructure of vegetative and reproductive structures of Coemansia reversa (Kickxellaceae, Zygomycetes). Afr. J. Mycol. Biotechnol., 10: 49-60.
  44. Abul-Hamd, A.T., M.E. Zain, H.M. Atta and R.A. Bayoumi, 2002. Genetic comparison of yeast strains using amplified fragment length polymorphism (AFLP) analysis. Egypt. J. Biomed. Sci., 10: 203-216.
  45. Zain, M.E., 2001. Effect of indol-3-acetic acid and 2,4- dichlorophenoxy acetic acid on growth and secondary metabolites production of Aspergillus flavus. J. Educ. Faculty, 26: 323-329.
  46. Awaad, A.S. and M.E. Zain, 1999. Cyperus alopecuroids: Coumarins and antimicrobial activity. Egypt. J. Pharm. Sci., 40: 107-116.
  47. Razak, A.A., H.H. El-Sheikh and M.E. Zain, 1997. Proteins and free amino acids as taxonomic markers in species level of the genus Aspergillus. Afr. J. Mycol. Biotechnol., 5: 1-17.
  48. Razak, A.A., H.H. El-Sheikh, M.E. Zaki and M.E. Zain, 1996. Proteins and free amino acids as taxonomic markers in taxa level of the genus Aspergillus. Afr. J. Mycol. Biotechnol., 4: 1-17.