Dr. Magdy Mahfouz Youssef
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Dr. Magdy Mahfouz Youssef

Research Scientist
Department of Chemistry, Faculty of Science, Mansoura University, Egypt

Highest Degree
Ph.D. in Molecular Biology and Genetics from Bradford University, UK

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Area of Interest:

Biomedical Sciences
100%
Biochemistry
62%
Enzyme Kinetics
90%
Molecualar Biology
75%
Protein Chemistry
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
68
Abstracts
16

Selected Publications

  1. Shawki, H.A., R. Elzehery, M. Shahin, E.M. Abo-Hashem and M.M. Youssef, 2021. Evaluation of some oxidative markers in diabetes and diabetic retinopathy. Diabetology Int., 12: 108-117.
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  2. Hosny, S., H. Sahyon, M. Youssef and A. Negm, 2021. Oleanolic acid suppressed DMBA-induced liver carcinogenesis through induction of mitochondrial-mediated apoptosis and autophagy. Nutr. Cancer, 73: 968-982.
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  3. Shawki, H.A., R. Elzehery, E.M. Abo-Hashem, M. Shahin and M.M. Youssef, 2020. Gene polymorphism of C106T “rs759853” is not associated with diabetic retinopathy in Egyptian patients with type 2 diabetes mellitus. Gene Rep., Vol. 21. 10.1016/j.genrep.2020.100865.
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  4. Sabry, S.A., F.F. El-Senduny, N.K. Abousamra, M.S. El-Din and M.M. Youssef, 2020. Oxidative stress in CLL patients leads to activation of Th9 cells: An experimental and comprehensive survey. Immunol. Med., 43: 36-46.
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  5. Moussa, M., A. Badawy, N. Helal, F. Hegab and M. Youssef et al., 2020. Differential expression of HER2 and SKP2 in benign and malignant colorectal lesions. Asian Pac. J. Cancer Prev., 21: 2357-2366.
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  6. El-Shaheed, S., H. Sahyon, M. Youssef and A. Negm, 2020. Protocatechuic acid decreased telomerase reverse transcriptase (TERT) expression in DMBA-induced liver carcinogenesis mice model. Ann. Cancer Res. Therap., 28: 25-31.
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  7. Ibrahim, M.G., F.F. El-Senduny, M.M. Youssef, D.M. Elimam, F.M. Abdel Bar and F.A. Badria, 2019. Acetyl glycyrrhetinic acid methyl ester as a promising glycyrrhizin derivative against the breast cancer cells (MCF-7). J. Rep. Pharm. Sci., 8: 161-171.
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  8. Fetoh, A., M.A. Mohammed, M.M. Youssef and G.M. Abu El-Reash, 2019. Synthesis, characterization, cyclic voltammetry and biological studies of Zn (II), Cd (II), Hg (II) and UO22+ complexes of thiosemicarbazone salt. Appl. Organometal. Chem., Vol. 33. 10.1002/aoc.4787.
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  9. Fetoh, A., M.A. Mohammed, M.M. Youssef and G.M. Abu El-Reash, 2019. Characterization, cyclic voltammetry and biological studies of divalent Co, Ni and Cu complexes of water-soluble, bioactive and photoactive thiosemicarbazone salt. J. Mol. Liq., Vol. 287. 10.1016/j.molliq.2019.110958.
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  10. Elghazy, A.M., A.M. Elsaeid, M. Refaat and M.M. Youssef, 2019. Biochemical studies of adiponectin gene polymorphism in patients with obesity in Egyptians. Arch. Physiol. Biochem., 10.1080/13813455.2019.1662451.
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  11. El-Senduny, F.F., M.M. Zidane, M.M. Youssef and F.A. Badria, 2019. An approach to treatment of liver cancer by novel glycyrrhizin derivative. Anti-Cancer Agents Med. Chem., 19: 1863-1873.
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  12. El-Bendary, M., M. Neamatallah, H. Elalfy, T. Besheer and M. El-Setouhy et al., 2019. Association of genetic polymorphisms of chemokines and their receptors with clearance or persistence of hepatitis C virus infection. Br. J. Biomed. Sci., 76: 11-16.
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  13. Al-Omair, M., A. Sayed and M. Youssef, 2018. Synthesis and biological evaluation of bisthiazoles and polythiazoles. Molecules, Vol. 23. 10.3390/molecules23051133.
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  14. Sayed, A.R., M.M. Youssef and S.S. Al-Shihry, 2017. Synthesis and biochemical studies of novel thiadiazoles. Curr. Org. Synth., 14: 1052-1058.
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  15. Ismail, M.A., M.M. Youssef, R.K. Arafa, S.S. Al-Shihry and W.M. El-Sayed, 2017. Synthesis and antiproliferative activity of monocationic arylthiophene derivatives. Eur. J. Med. Chem., 126: 789-798.
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  16. Elghamry, I., U. El-Ayaan, M.M. Youssef, S. Al-Shihry, M. Letzel and J. Mattay, 2017. Photochemical and DNA degradation studies on tenoxicam, lornoxicam and their photolysis products. Monatshefte fur Chemie-Chem. Monthly, 148: 257-262.
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  17. Elghamry, I., M.M. Youssef, M.A. Al-Omair and H. Elsawy, 2017. Synthesis, antimicrobial, DNA cleavage and antioxidant activities of tricyclic sultams derived from saccharin. Eur. J. Med. Chem., 139: 107-113.
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  18. Youssef, M.M., R.K Arafa and M. AIsmail, 2016. Synthesis, antimicrobial and antiproliferative activities of substituted phenylfuranylnicotinamidines. Drug Des. Dev. Therapy, 10: 1133-1146.
    CrossRef  |  
  19. Adam, M.S.S., M.M. Youssef, M.F. Aboelghar, A.M. Hafez and U. El-Ayaan, 2016. Synthesis and characterization of binary and ternary oxovanadium complexes of N,N -(2-pyridyl)thiourea and curcumin: Catalytic oxidation potential, antibacterial, antimicrobial, antioxidant and DNA interaction studies: Oxovandium complexes of N,N-(2-pyridyl)thiourea and curcumin. Applied Organometal. Chem. 10.1002/aoc.3650.
    CrossRef  |  
  20. Youssef, M.M., 2015. Overexpression, purification, immobilization and characterization of thermophilic lipase from Burkholderia pseudomallei. Am. J. Microbiol. Biotechnol., 2: 82-91.
  21. Youssef, M.M. and M.A. Al-Omair, 2015. Identifying the putative interacting partners of the heat shock protein, HtpG through phage display library screening. Asian J. Biochem., 10: 1-16.
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  22. Sayed, A.R., M.M. Youssef and Y.S. Al-Faiyz, 2015. Synthesis, characterization and biological evaluation of novel thiadiazoline sulfonamides and metal complexes. J. Applied Sci., 15: 884-893.
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  23. Magdy M. Youssef, Ahmed A. Mahmoud, Yasair S.S. Al-Faiyz 2015. Antimicrobial and Antioxidant Activities of Artemisia abyssinica Extracts and DNA Degradation Effects Asian J. Biochem., 10: 31-41.
    CrossRef  |  
  24. Al-Omair, M.A., A.R. Sayed and M.M. Youssef, 2015. Synthesis of novel triazoles, tetrazine, thiadiazoles and their biological activities. Molecules, 20: 2591-2610.
    CrossRef  |  
  25. Youssef, M.M., M.A. Al-Omair and S.M. Picksley, 2014. Genetic characterization of Escherichia coli RecN protein as a member of SMC family of proteins. Arab. J. Chem., 7: 327-334.
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  26. Youssef, M.M. and M.A. Al-Omair, 2014. Identifying the polypeptide active partners and the dimer binding sites of HtpG protein applying 12 mer phage library. Int. J. Curr. Microbiol. Applied Sci., 3: 489-504.
  27. Ismail, M.A., R.K. Arafa, M.M. Youssef and W.M. El-Sayed, 2014. Anticancer, antioxidant activities and DNA affinity of novel monocationic bithiophenes and analogues. Drug Des. Dev. Therapy, 8: 1659-1672.
    CrossRef  |  
  28. Gouda, M., U. Elayaan and M.M. Youssef, 2014. Synthesis and biological activity of drug delivery system based on chitosan nanocapsules. Adv. Nanoparticles, 3: 148-158.
    CrossRef  |  
  29. Youssef, M.M. and M.M. Azooz, 2013. Biochemical studies on the effects of zinc and lead on oxidative stress, antioxidant enzymes and lipid peroxidation in Okra (Hibiscus esculentus cv. Hassawi). Sci. Int., 1: 29-38.
    CrossRef  |  
  30. Azooz, M.M., A.M. Alzahrani and M.M. Youssef, 2013. The potential role of seed priming with ascorbic acid and nicotinamide and their interactions to enhance salt tolerance in broad bean (Vicia faba L.). Aust. J. Crop Sci., 7: 2091-2100.
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  31. Youssef, M.M., Y.A. Hussein, S.S. Al-Shokair, S.R. Ghodake and A.N. Suryakar et al., 2012. Toxicity, antioxidative, antibacterial and biological activities of poisonous plants of al-hassa. BioChem. Indian J., 6: 145-150.
  32. Youssef, M.M., Y.A. Hussein, A.R. Heraba and S.S. Al-Shokair, 2012. Forensic biological identifications of mammal species through DNA barcodes. BioChem. Indian J., 6: 71-77.
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  33. Youssef, M.M., M.A. Al-Omair and M.A. Ismail, 2012. Synthesis, DNA affinity and antimicrobial activity of 4-substituted phenyl-2,2'-bichalcophenes and aza-analogues. Med. Chem. Res., 21: 4074-4082.
    CrossRef  |  
  34. Azooz, M.M., M.M. Youssef and M.A. Al-Omair, 2011. Comparative evaluation of zinc and lead and their synergistic effects on growth and some physiological responses of Hassawi Okra (Hibiscus esculentus) seedlings. Am. J. Plant Physiol., 6: 269-282.
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  35. Alzahrani, A.M., A.A. Fathi and M.M. Youssef, 2011. Physiological and biochemical studies on the response of tolerant versus wild type of Chlorella vulgaris to copper stress. King Abdul Aziz Bull. Sci., Vol. 23 (In Press) .
  36. Zakaria, S., M. Youssef, M. Moussa, M. Akl and E. El-Ahwany et al., 2010. Value of α-smooth muscle actin and glial fibrillary acidic protein in predicting early hepatic fibrosis in chronic hepatitis C virus infection. Arch. Med. Sci., 3: 356-365.
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  37. Azooz, M.M. and M.M. Youssef, 2010. Evaluation of heat shock and salicylic acid treatments as inducers of drought stress tolerance in hassawi wheat. Am. J. Plant Physiol., 5: 56-70.
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  38. Al-Mohammed, H.I. and M.M. Youssef, 2010. Polyacrylamide Gel Electrophoresis of Proteins Extracted from Nematotaenia Dispar which Isolated from Varanus griseus in Saudi Arabia. Res. J. Biol. Sci., 5: 735-738.
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  39. El-Ayaan, U., M.M. Youssef and S. Al-Shihry, 2009. Mn(II), Co(II), Zn(II), Fe(III) and U (VI) complexes of 2-acetylpyridine 4N-(2-pyridyl) thiosemicarbazone (HAPT); structural, spectroscopic and biological studies. J. Mol. Struct., 936: 213-219.
    CrossRef  |  
  40. Youssef, M.M. and M.A. Al-Omair, 2008. Cloning, purification, characterization and immobilization of L-asparaginase II from E. coli W3110. Asian J. Biochem., 3: 337-350.
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  41. El-Shora, H.M., M.M. Youssef and A.S. Khalaf, 2008. Inducers and inhibitors of laccase from Penicillium. Biotechnology, 7: 35-42.
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  42. El-Shora, H.M. and M.M. Youssef, 2008. Identification of catalytically essential amino acid residues and immobilization of glutamate dehydrogenase from Rumex cotyledons. Asian J. Biochem., 3: 320-329.
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  43. Dawidar, A.M., M. Abdel-Mogib, A.M. El-Ghorab, M. Mahfouz, F.G. El-Said and K. Hussien, 2008. Chemical composition and effect of photo-oxygenation on biological activities of Egyptian commercial anise and fennel essential oils. J. Essential Oil-Bearing Plants, 11: 124-136.
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  44. Al-Omair, M.A. and M.M. Youssef, 2008. Biochemical studies on the effect of selenium and α-difluromethylornithine on the elevated polyamines in mice. J. Biol. Sci., 8: 1149-1157.
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  45. El-Ayaan, U., N.M. El-Metwally, M.M. Youssef and S.A.A. El-Bialy, 2007. Perchlorate mixed-ligand copper(II) complexes of beta-diketone and ethylene diamine derivatives: Thermal, spectroscopic and biochemical studies. Spectrochim. Acta A Mol. Biomol. Spectrosc., 68: 1278-1286.
    PubMed  |  
  46. Youssef, M.M. and Y.A. Osman, 2006. Purification and characterization of a novel restriction enzyme from Bacillus thuringiensis Neide. Proceedings of the 1st Microbiology Symposium, July 4-6, 2006, Mansoura, pp: 30-41.
  47. Youssef, M.M. and S.A. Habib, 2006. Site directed mutagensis in Walker A nucleotide binding site of SbcC protein of E. coli. Egypt. J. Biomed.Sci., 20: 337-350.
  48. Youssef, M.M., H.M. El-Shora and A.M. El-Waseef, 2005. Purification and biochemical characterization of glucose dehydrogenase from orange fruit. Proceedings of the International Conference on Chemistry and its Role in Development, April 11-14, 2005, Mansoura University -.
  49. Youssef, M.M., H.M. El-Shora and A.M. El-Waseef, 2005. Biochemical characterization of glucose dehydrogenase from orange fruit. Proceedings of the International Conference on Chemistry and its Role in Development, April 11-14, 2005, Mansoura University -.
  50. El-Shora, H.M., M.M. Youssef and A.K. Salwa, 2005. Induction and immobilization of asparaginase from Aspergillus niger. Biochem. Lett., 1: 35-46.
  51. El-Shora, H.M., S.A. Khalaf and M.M. Youssef, 2004. Biochemical properties and immobilization of phytase from Penicillium digitatum. Mans. Sci. Bull., 30: 141-156.
  52. El-Shora, H.M., E.M. Abo-Kassem and M.M. Youssef, 2004. The toxic effects of cadmium and copper on the antioxidative enzymes and lipid peroxidation in marrow roots. Mans. Sci. Bull., 30: 127-140.
  53. Youssef, M.M., H.M. El-Shora and S.A. Khalaf, 2003. Purification and biochemical characterization of laccase from green Penicilli. Proceedings of the 2nd International Conference on Chemistry and its Application, December, 2003, Qutar -.