Dr. Mohamed Zakaria Gad
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Dr. Mohamed Zakaria Gad

Professor and Vice-Dean
Faculty of Postgraduate Studies & Scientific Research, The German University in Cairo, Egypt


Highest Degree
Ph.D. in Biochemistry from The Medical College of Pennsylvania, USA

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Biography

Dr. Mohamed Z. Gad is currently working as Professor and Chairman of Biochemistry Department, The German University in Cairo, Faculty of Pharmacy, Egypt. His prior work experience includes Acting Dean, Vice-Dean for Research & Graduate Studies, Assistant lecturer, Associate Professor and Demonstrator of Biochemistry in different institutes. He completed his Ph.D. in Biochemistry from The Medical College of Pennsylvania PA, USA. He is here with 25 years teaching experience in Biochemistry and 35 years scientific experience. He has received number of awards and honors in different categories. His area of research interest includes pharmaceutical education, nitric oxide, clinical pharmacology of L-arginine, biochemical mechanisms of natural products, pharmacogenomics, biological antioxidants, lipoprotein metabolism, lipid enzymology, subcellular fractionation, esterases and detoxification enzymes, mechanisms of intracellular transport, membrane biochemistry, and biotechnology He also served as external thesis examiner and also supervised thesis of PhD and MSc. He has received STDF (Science and Technology Development Fund) grant 2951 entitled “Exploring genetic susceptibility to cardiovascular disease in Egyptians: correlation to biochemical investigations”. He actively attended and presented more than 70 research papers in conferences, seminars and annual meetings. He has published more than 54 research articles in national and international journals. He is also member of different journals and professional bodies.

Area of Interest:

Pharmacology and Toxicology
100%
Biochemistry
62%
Nitric Oxide
90%
Clinical Pharmacology
75%
Pharmaceutical Sciences
55%

Research Publications in Numbers

Books
5
Chapters
3
Articles
96
Abstracts
117

Selected Publications

  1. Farag, M.A. and M.Z. Gad, 2022. Omega-9 fatty acids: Potential roles in inflammation and cancer management. J. Genet. Eng. Biotechnol. Vol. 20. 10.1186/s43141-022-00329-0.
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  2. Fahmy, S.A., A. Ramzy, A.M. Sawy, M. Nabil, M.Z. Gad, M. El-Shazly and M.A.M. Aboul-Soud et al, 2022. Ozonated olive oil: Enhanced cutaneous delivery via niosomal nanovesicles for melanoma treatment. Antioxidants, Vol.11. 10.3390/antiox11071318.
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  3. Elsabbagh, R.A., M. Rady, C. Watzl, K. Abou-Aisha and M.Z. Gad, 2022. Impact of N6-methyladenosine (m6A) modification on immunity. Cell Commun. Signal., 10.1186/s12964-022-00939-8.
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  4. Abdel-Latif, M., A. Riad, R.A. Soliman, A.M. Elkhouly, H. Nafae, M.Z. Gad and A. Abdel Motaal et al., 2022. MALAT-1/p53/miR-155/miR-146a ceRNA circuit tuned by methoxylated quercitin glycoside alters immunogenic and oncogenic profiles of breast cancer. Mol. Cell Biochem., 477: 1281-1293.
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  5. Selem, N.A., R.A. Youness and M.Z. Gad, 2021. What is beyond lncRNAs in breast cancer: A special focus on colon cancer-associated transcript-1 (CCAT-1). Non-coding RNA Res., 6: 174-186.
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  6. Nafea, H., R.A. Youness, K. Abou‐Aisha and M.Z. Gad, 2021. LncRNA HEIH/miR‐939‐5p interplay modulates triple‐negative breast cancer progression through NOS2‐induced nitric oxide production. J. Cell. Physiol. 236: 5362-5372.
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  7. Kilany, F.H.E., R. A. Youness, R.A. Assal and M.Z. Gad, 2021. MiR-744/eNOS/NO axis: A novel target to halt triple negative breast cancer progression. Breast Dis., 40: 161-169.
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  8. Hashad, I.M., H. Nosseir, G.M. Shaban, M.F. Abdel Rahman and M.Z. Gad, 2021. Is there a correlation between -174(G/C) polymorphism of IL-6 gene and the incidence of acute myocardial infarction? J. Genet. Eng. Biotechnol. Vol. 19. 10.1186/s43141-021-00243-x.
    CrossRef  |  Direct Link  |  
  9. Gad, M.Z., S.S. Azab, A.R. Khattab and M.A. Farag, 2021. Over a century since ephedrine discovery: An updated revisit to its pharmacological aspects, functionality and toxicity in comparison to its herbal extracts. Food Funct., 12: 9563-9582.
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  10. Elbehairy, M.M., H.Y. Abdelnasser, R.S. Hanafi, S.I. Hassanein and M.Z. Gad, 2021. An intronic DHCR7 genetic polymorphism associates with vitamin D serum level and incidence of acute coronary syndrome. Steroids. Vol. 169. 10.1016/j.steroids.2021.108825.
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  11. Youness, R.A., A.Z. Gad, K. Sanber, Y.J. Ahn and Gi-Ja Lee et al., 2020. Targeting hydrogen sulphide signaling in breast cancer. In: Journal of Advanced Research, Szabo, C., M.Z. Gad and M.A. Farag, Elsevier BV Netherlands pp: 14.
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  12. Elsabbagh, R.A., M.F. Abdel Rahman, S.I. Hassanein, R.S. Hanafi, R.A. Assal, G.M. Shaban and M.Z. Gad, 2020. The association of megalin and cubilin genetic variants with serum levels of 25-hydroxvitamin D and the incidence of acute coronary syndrome in Egyptians: A case control study. J. Adv. Res., 21: 49-56.
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  13. ElKhouly, A.M., R.A. Youness and M.Z. Gad, 2020. MicroRNA-486-5p and microRNA-486-3p: Multifaceted pleiotropic mediators in oncological and non-oncological conditions. Non-coding RNA Res., 5: 11-21.
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  14. El Din, G.S., R.A. Youness, R.A. Assal and M.Z. Gad, 2020. miRNA-506-3p directly regulates rs10754339 (A/G) in the immune checkpoint protein B7-H4 in breast cancer. MicroRNA, 9: 346-353.
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  15. Ammar, M.K., H. Handoussa, R.S. Hanafi, M. El-Shazly, M.Z. Gad, 2020. Multivariate approach for optimization of galactomannan extraction from seeds of Egyptian Trigonella foenum-graecum with insights on its pharmacological activities. Nat. Prod. Res., 36: 2125-2128.
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  16. Youness, R.A., H.M. Hafez, E. Khallaf, R.A. Assal, A. Abdel Motaal and M.Z. Gad, 2019. The long noncoding RNA sONE represses triple‐negative breast cancer aggressiveness through inducing the expression of miR‐34a, miR‐15a, miR‐16, and let‐7a. J. Cell. Physiol., 234: 20286-20297.
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  17. Youness, R.A. and M.Z. Gad, 2019. Long non-coding RNAs: Functional regulatory players in breast cancer. Non-coding RNA Res., 4: 36-44.
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  18. Fam, M.S., S.I. Hassanein, M.F. Abdel Rahman, R.A. Assal, R.S. Hanafi and M.Z. Gad, 2019. Contribution of CYP27B1 and CYP24A1 genetic variations to the incidence of acute coronary syndrome and to vitamin D serum level. Can. J. Physiol. Pharmacol., 97: 1152-1158.
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  19. Awad, A.R., R.A. Youness, M. Ibrahim, A. Abdel Motaal, H.I. El-Askary, R.A. Assal and M.Z. Gad, 2019. An acetylated derivative of vitexin halts MDA-MB-231 cellular progression and improves its immunogenic profile through tuning miR- 20a-MICA/B axis. Nat. Prod. Res., 35: 3126-3130.
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  20. Alyan, A.K., R.S. Hanafi and M.Z. Gad. 2019. Point-of-care testing and optimization of sample treatment for fluorometric determination of hydrogen sulphide in plasma of cardiovascular patients. In: Journal of advanced research. Szabo, C., M.Z. Gad and M.A. Farag Elsevier BV Netherlands pp: 10.
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  21. Youness, R.A., R.A. Assal, A. Abdel Motaal and M.Z. Gad, 2018. A novel role of sONE/NOS3/NO signaling cascade in mediating hydrogen sulphide bilateral effects on triple negative breast cancer progression. Nitric Oxide, 80: 12-23.
    CrossRef  |  Direct Link  |  
  22. Sedky, N.K., M.F. Abdel Rahman, S.I. Hassanein and M.Z. Gad, 2018. Genetic variants of CYP2R1 are key regulators of serum vitamin D levels and incidence of myocardial infarction in middle-aged Egyptians. Current Pharm. Biotechnol., 19: 265-273.
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  23. Hashad, I.M., N.M. Hossni, M.F. Abdel Rahman, M. Shehata, G. Shaban and M.Z. Gad, 2018. C(-260)T polymorphism in CD14 receptor gene of Egyptians with acute myocardial infarction. Current Pharm. Biotechnol., 19: 336-342.
    CrossRef  |  Direct Link  |  
  24. Amir, M., S.I. Hassanein, M.F. Abdel Rahman and M.Z. Gad, 2018. AGXT2 and DDAH-1 genetic variants are highly correlated with serum ADMA and SDMA levels and with incidence of coronary artery disease in Egyptians. Mol. Biol. Rep., 45: 2411-2419.
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  25. Abu el Maaty, M.A., R.S. Hanafi, H.Y. Aboul-Enein and M.Z. Gad, 2015. Design-of-experiment approach for HPLC analysis of 25-hydroxyvitamind. A comparative assay with ELISA. J. Chromatogr. Sci., 53: 66-72.
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  26. Maher, A., N.S. El-Sayed, H.G. Breitinger and M.Z. Gad, 2014. Overexpression of NMDAR2B in an inflammatory model of Alzheimer's Disease: modulation by NOS inhibitors. Brain Res. Bull., 109: 109-116.
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  27. Hassanein, S.I., M.A. Abu-el-Maaty, H.M. Sleem, M.Z. Gad, 2014. Triangular relationship between single nucleotide polymorphisms in the CYP2R1 gene (rs10741657 and rs12794714), 25-hydroxyvitamin d levels, and coronary artery disease incidence. Biomarkers, 19: 488-492.
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  28. Hashad , I.M., M.F.A. Rahman, S.M. Abdel-Maksoud, K.S. Amr, L.K. Effat, G.M. Shaban and M.Z. Gad, 2014. C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population. Mol. Biol. Rep., 41: 2281-2286.
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  29. Gad, M.Z., M.A. Abu El Maaty, S.A. El-Maraghy, A.T. Fahim and M.A. Hamdy, 2014. Investigating the cardio-protective abilities of supplemental l-arginine on parameters of endothelial function in hypercholesterolemic animal model. J. Nutr. Sci. Vitaminol., 60: 145-151.
    CrossRef  |  
  30. Abu el Maaty, M.A.. S.I. Hassanein, H.M. Sleem and M.Z. Gad, 2014. Vitamin D receptor gene polymorphisms (TaqI and ApaI) in relation to 25-hydroxyvitamin D levels and coronary artery disease incidence. J. Rec. Sig. Trans. Res., 16: 1-5.
    CrossRef  |  
  31. Abu el Maaty, M.A., R.S. Hanafi, S. El-Badawy and M.Z. Gad, 2014. Interplay of vitamin D and nitric oxide in post-menopausal knee osteoarthritis. Aging Clin. Exp. Res., 26: 363-368.
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  32. Abdel Rahman, M.F., I.M. Hashad, K. Abou-Aisha, S.M. Abdel-Maksoud and M.Z. Gad, 2014. Addressing the link between paraoxonase-1 gene variants and the incidence of early onset myocardial infarction,. Arch. Med. Sci., 3: 513-520.
    CrossRef  |  
  33. Abu el Maaty, M.A., S.I. Hassanein, R.S. Hanafi and M.Z. Gad, 2013. Insights on vitamin D�s role in cardiovascular disease: Investigating the association of 25-Hydroxyvitamin D with the dimethylated arginines. J. Nutr. Sci. Vitaminol., 59: 172-177.
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  34. Abu el Maaty, M.A., S.I. Hassanein, H.M. Sleem and M.Z. Gad, 2013. Effect of polymorphisms in the NADSYN1/DHCR7 locus (rs12785878 and rs1790349) on plasma 25-hydroxyvitamin D levels and coronary artery disease incidence. J. Nutrigenet. Nutrigenomics., 6: 327-335.
  35. Abu el Maaty, M.A., R.S. Hanafi, S. El Badawy and M.Z. Gad, 2013. Association of suboptimal 25-Hydroxyvitamin D levels with knee osteoarthritis incidence in post-menopausal Egyptian women. Rheumatol Int., 33: 2903-2907.
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  36. Abu el Maaty, M.A. and M.Z. Gad, 2013. Vitamin D deficiency and cardiovascular disease: potential mechanisms and novel perspectives. J. Nutr. Sci. Vitaminol., 59: 59-88.
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  37. Abdel-Maksoud, S., S. Ibrahim, F. Samir, K. Abou-Aisha and M.Z. Gad, 2013. Correlation of Glu298Asp eNOS polymorphism with serum no levels in egyptian patients with coronary artery disease. Br. J. Med. Med. Res., 3: 1678-1687.
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  38. Khalifa, N.M., M.Z. Gad, A.A. Hataba and L.G. Mahran, 2012. Changes in ADMA and TAFI after stenting in coronary artery disease patients. Mol. Med. Report, 6: 855-859.
  39. Gad, M.Z., M.F. Abdel Rahman, I.M. Hashad, S.M. Abdel-Maksoud, N.M. Farag and K. Abou-Aisha, 2012. Endothelial nitric oxide synthase (G894T) gene polymorphism in a random sample of egyptian population: Comparison with myocardial infarction patients. Genet. Test Mol. Biomarkers, 16: 695-700.
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  40. Aboul-Maaty, M., R.S. Hanafi and M.Z. Gad, 2012. Is there a relationship between vitamin D deficiency and the incidence of osteoarthritis? A clinical/comparative-assay study of HPLC-UV versus ELISA. Clin. Chem. Lab. Med., 50: A94-A94.
  41. Saleh, A.I., S.M. Abdel Maksoud, S.A. El-Maraghy and M.Z. Gad, 2011. Protective effect of L-arginine in experimentally induced myocardial ischemia: Comparison with aspirin. J. Cardiovasc. Pharmacol. Ther., 16: 53-62.
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  42. Gad, M.Z., S.I. Hassanein, S.M. Abdel-Maksoud, G.M. Shaban and K. Abou-Aisha, 2011. Association of DDAH2 gene polymorphism with cardiovascular disease in egyptian patients. J. Genet., 90: 161-163.
  43. Gad, M.Z., N.A. Ehssan, M.H. Ghiet and L.F. Wahman, 2011. Effects of pioglitazone and metformin on carbohydrate metabolism in experimental models of glucose intolerance. Int. J. Diabetes Metab., 18: 132-138.
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  44. Gad, M.Z., S.I. Hassanein, S.M. Abdel-Maksoud, G.M. Shaban,, K. Abou-Aisha, A. Hossam and H.A. Elgabarty, 2010. Assessment of serum levels of asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and L-arginine in coronary artery disease. Biomarker, 15: 746-746.
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  45. Gad, M.Z., N.A. Ehssan, M.H. Ghiet and L.F. Wahman, 2010. Pioglitazone versus metformin in two rat models of glucose intolerance and diabetes. Pak. J. Pharm. Sci., 23: 305-312.
    PubMed  |  
  46. Gad, M.Z., 2010. Anti-aging Effects of L-Arginine (Review Article). J. Adv. Res., 1: 169-177.
  47. El-Demerdash, E., H.O. El-Mesallamy, N.M. Abu-Zaid and M.Z. Gad, 2010. The potential therapeutic effect of nitric oxide modulators in experimentally-induced gastric ulcers. Drug Discov. Ther., 4: 276-284.
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  48. Nasralla, S.N., A.I. Ghoneim, A.E. Khalifa, M.Z. Gad and A.B. Abdel-Naim, 2009. Lactoperoxidase catalyzes in-vitro activation of acrylonitrile to cyanide. Toxicol. Lett., 191: 347-352.
    PubMed  |  
  49. Gad, M.Z., H.O. El-Mesallamy and E.F. Sanad, 2008. hsCRP, sICAM-1 and TAFI in hemodialysis patients: linking inflammation and hypofibrinolysis to cardiovascular events. Kidney Blood Press Res., 31: 391-397.
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  50. El-Mesallamy, H.O., S.G. Abdel Hamid and M.Z. Gad, 2008. Oxidative stress and asymmetric dimethylarginine are associated with cardiovascular complications in hemodialysis patients: improvements by L-arginine intake. Kidney Blood Press Res., 31: 189-195.
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  51. El-Mesallamy, H.O., R.S. Salah and M.Z. Gad, 2008. Study of some inflammatory factors in type 2 diabetic patients with nephropathy. J. Med. Sci., 8: 532-539.
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  52. El-Mesallamy, H.O., M.Z. Gad and A.M. Sallam, 2008. The association of TGF-β1, angiotensin II and oxidative stress with diabetic nephropathy in type 2 diabetic patients. Int. J. Diabetes Metab., 16: 63-68.
    Direct Link  |  
  53. Gad, M.Z., C.O. Ali, M. Sills and S. Von-Laue, 2007. A Model Pharmacy Curriculum: An Egyptian-European Experience. Health Sciences and Practice Subject Center, UK.
  54. El-Maraghy, S.A., M.Z. Gad, A.T. Fahim and M.A. Hamdy, 2007. L-arginine supplement, the natural protection from cardiovascular disease: unraveling the biochemical mechanisms. Arab. J. Lab. Med., 33: 333-353.
  55. Gad, M.Z., M.M. El-Sawalhi, M.F. Ismail and N.D. El-Tanbouly, 2006. Biochemical study of the anti-diabetic action of the Egyptian plants Fenugreek and Balanites. Mol. Cell. Biochem., 281: 173-183.
    CrossRef  |  PubMed  |  Direct Link  |  
  56. Khaleel, A.E., M.Z. Gad, S.A. El-Maraghy, M.S. Hifnawy and E. Abdel-Sattar, 2005. Study of hypocholesterolemic and antiatherosclerotic properties of Medicago sativa L. cultivated in Egypt. J. Food Drug Anal., 13: 212-218.
    Direct Link  |  
  57. Khaleel, A.E., M.Z. Gad, S.A. El-Maraghy, M.S. Hifnawy and E. Abdel-Sattar, 2005. Study of hypocholesterolemic and antiatherosclerotic properties of Medicago sativa L. cultivated in Egypt. J. Food Drug Anal., 13: 212-218.
  58. Hanna, E.T., M.Z. Gad, N.S. Bassily, F.I. El-Nahry and N.A. Ismail, 2002. Effect of different types of dietary fat on the lipid profile of rats. Egypt. J. Nutr., 2: 173-195.
  59. Sayed-Ahmed, M.M., M.M. Khattab, M.Z. Gad and N.A. Moustafa, 2001. L-carnitine prevents the progression of atherosclerotic lesions in hypercholesterolemic rabbits. Pharmacol. Res., 44: 235-242.
  60. Sayed-Ahmed, M.M., M.M. Khattab, M.Z. Gad and N. Mostafa, 2001. L-carnitine prevents the progression of atherosclerotic lesions in hypercholesterolaemic rabbits. Pharmacol. Res., 44: 235-242.
    Direct Link  |  
  61. Sayed-Ahmed, M.M., M.M. Khattab, M.Z. Gad and A.M. Osman, 2001. Increased plasma endothelin-1 and cardiac nitric oxide during doxorubicin-induced cardiomyopathy. Pharmacol. Toxicol., 89: 140-144.
    Direct Link  |  
  62. Sayed-Ahmed, M.M., M.M. Khattab, M.Z. Gad and A.M. Osman, 2001. Increased plasma endothelin-1 and cardiac nitric oxide during Doxorubicin-induced cardiomyopathy. Pharmacol. Toxicol., 89: 140-144.
  63. Kheir-Eldin, A.A., T.K. Motawi, M.Z. Gad and H.M. Abd-ElGawad, 2001. Protective effect of vitamin E, beta-carotene and N-acetylcysteine from the brain oxidative stress induced in rats by lipopolysaccharide. Int. J. Biochem. Cell Biol., 33: 475-482.
    CrossRef  |  PubMed  |  
  64. Kheir-Eldin, A., T.K. Motawi, M.Z. Gad and H. Abd El-Gawad, 2001. Protective effect of vitamin E, beta-carotene and N-acetylcysteine from the brain oxidative stress induced in rats by lipopolysaccharide. Int. J. Biochem. Cell Biol., 33: 475-475.
  65. Khattab, M.M., M.Z. Gad and D.M. Abdallah, 2001. Protective role of nitric oxide in indomethacin-induced gastric ulceration by a mechanism independent on gastric acid secretion. Pharmacol. Res., 43: 463-467.
  66. Khattab, M.M., M.Z. Gad and D. Abdallah, 2001. Protective role of nitric oxide in indomethacin-induced gastric ulceration by a mechanism independent of gastric acid secretion. Pharmacol. Res., 43: 463-467.
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  67. Gad, M.Z., M.M. Khattab, N.A. Moustafa and J. Burgaud, 2001. Regression of early events of atherosclerosis in hypercholesterolemic rabbits by prophylactic treatment with nitroderivative of acetyl salicylic. Drug. Dev. Res., 53: 237-243.
  68. El-Maraghy, S.A., M.Z. Gad, A.T. Fahim and M.A. Hamdy, 2001. Effect of cadmium and aluminum intake on the antioxidant status and lipid peroxidation in rat tissues. J. Biochem. Mol. Toxicol., 15: 207-214.
    Direct Link  |  
  69. EI-Maraghy, S.A., M.Z. Gad, A.T. Fahim and M.A. Hamdy, 2001. Effect of Cadmium and Aluminum intake on the antioxidant status and lipid peroxidation in rat tissues. J. Biochem. Mol. Toxicol., 15: 207-214.
  70. Gad, M.Z. and M.M. Khattab, 2000. Modulation of nitric oxide synthesis in inflammation: relationship to oxygen-derived free radicals and prostaglandin synthesis. Arzneimittel-Fors., 50: 449-455.
  71. Ismail, M.F. M.Z.Gad and M.A. Hamdy, 1999. Study of the hypolipidemic properties of pectin, garlic and ginseng in hypercholesterolemic rabbits. Pharmacol. Res., 39: 157-166.
    PubMed  |  
  72. Matsuura, T., M.Z. Gad, E.H. Harrison and A.C. Ross, 1997. Lecithin: Retinol acyltransferase and retinyl ester hydrolase activities are differentially regulated by retinoids and have distinct distributions between hepatocyte and nonparenchymal cell fractions of rat liver. J. Nutr., 127: 218-224.
  73. Shaheen, A.A., A.A. Abd El-Fattah and M.Z. Gad, 1996. Effect of various stressors on the level of lipid peroxide, antioxidants and Na+, K+ -ATPase activity in rat brain. Cell. Mol. Life Sci., 52: 336-339.
  74. Ahmed, S.A. and M.Z. Gad, 1996. Diagnostic value of serum lactate dehydrogenase isoenzyme and amino acid patterns in schistosomal and non-schistosomal hepatic and bladder disorders as compared to other biochemical parameters. Dis. Markers, 13: 1-11.
  75. Harrison, E.H., M.Z. Gad and C.A. Ross, 1995. Hepatic uptake and metabolism of chylomicron retinyl esters: probable role of plasma membrane/endosomal retinyl ester hydrolases. J. Lipid. Res., 36: 1498-1506.
  76. Fahim, A.T., A.A. Abd-El Fattah, A.M. Agha and Z.M. Gad, 1995. Effect of pumpkin-seed oil on the level of free radical scavengers induced during adjuvant-arthritis in rats. Pharmacol. Res., 31: 73-79.
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  77. Fahim, A.T., A.A. Abd-EI Fattah, A.M. Agha and M.Z. Gad, 1995. Effect of pumpkin-seed oil on the level of free radical scavengers induced during adjuvant-arthritis in rats. Pharmacol. Res., 31: 73-79.
  78. Ahmed, S.A. and M.Z. Gad, 1995. Effect of schistosomal infection and its treatment on some key enzymes of glucose metabolism in mice livers. Arzneimittel Forschung, 45: 1324-1328.
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  79. Agha, A.M. and M.Z. Gad, 1995. Lipid peroxidation and lysosomal integrity in different inflammatory models in rats: The effect of Indomethacin and Naftazone. Pharmacol. Res., 32: 279-285.
  80. Gad, M.Z., A.A. Abd El Fattah, M. Seif EI-Nasr and A.S. Attia 1994. Acute and chronic effects of ethanol on rat brain neurotransmitters. Bull. Fac. Pharm. Cairo. Univ., 32: 321-321.
  81. Gad, M.Z., 1994. The distribution of non-specific carboxylesterases and glutathione S-transferases in different rat liver cells: Effect of vitamin A deficiency. Biochem. Pharmacol., 48: 139-144.
  82. Harrison, E.H., C.J. Rojas, M.Z. Gad and E.S. Kempner, 1993. Analysis of microsomal Cholesteryl ester hydrolases by radiation inactivation. J. Biol. Chem., 268: 17867-17870.
  83. Gad, M.Z. and E.H. Harrison, 1991. Neutral and acid retinyl ester hydrolases associated with rat liver microsomes: Relationships to microsomal Cholesteryl ester hydrolases. J. Lipid Res., 32: 685-693.
  84. Harrison, E.H. and M.Z. Gad, 1989. Hydrolysis of retinyl palmitate by enzymes of rat pancreas and liver. Differentiation of bile salt-dependent and bile salt-independent, neutral retinyl ester hydrolases in rat liver. J. Biol. Chem., 264: 17142-17147.
  85. Kheir El-Din A.A., T.K. Motawi and M.Z. Gad, 1988. Comparative study on the effects of Thiazolidinc-4-Carboxylic acid, Vitamin E and Adenosine on Ethionine-induced hepatotoxicity in rats. Bull. Egypt Soc. Physiol. Sci., 8: 226-240.