Dr. Mahmoud  Zaky Sitohy
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Dr. Mahmoud Zaky Sitohy

Professor
Zagazig University, Egypt


Highest Degree
Ph.D. in Biochemistry from Zagazig University, Zagazig, Egypt

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Biography

Dr. Mahmoud Zaky Sitohy is currently working as Executive Director of Project Management Unit, Zagazig University, Egypt, and Professor in Biochemistry Department, Faculty of Agriculture at Zagazig University, Egypt. He obtained his PhD in Biochemistry from Zagazig University in 1983. He is professional member of American Chemical Society, Sigma Xi, Society for Green Vegetation Research, Egyptian Biochemical Society, French Academic Society, Egyptian Medical Biochemical Society, Egyptian Agricultural Biochemistry Society. He is having 43 years of professional experience encompassing management of international research projects. In past he worked as Demonstrator-Assistant lecturer, Assistant Professor, Full professor at Zagazig University, Visiting Scientific at NIRD Reading University, Visiting Assistant Professor at University of California, Examiner at Egyptian Universities, Visiting Researcher at INRA-Nantes, Project Assessor at RDI, Ministry of Higher Education, Assessor and Evaluator at Ministry of Higher Education, Senior Expert at ASRT Ministry of Research. His recent publication includes, 24 articles in journals contributed as author/co-author.

Area of Interest:

Chemistry
100%
Organic Chemistry
62%
Biochemistry
90%
Molecular Modelling
75%
Synthesis
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Osman, A., H.A. Goda and M. Sitohy, 2018. Storage stability of minced beef supplemented with chickpea legumin at 4°C as a potential substitute for nisin. LWT, Food Sci. Technol., 93: 434-441.
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  2. Hashish, E., A. Merwad, S. Elgaml, A. Amer and H. Kamal et al., 2018. Mycobacterium marinum infection in fish and man: Epidemiology, pathophysiology and management. A review. Vet. Quart., 38: 35-46.
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  3. El-Sayed, A.S., S. Safan, N.Z. Mohamed, L. Shaban, G.S. Ali and M.Z. Sitohy, 2018. Induction of taxol biosynthesis by Aspergillus terreus, endophyte of Podocarpus gracilior Pilger, upon intimate interaction with the plant endogenous microbes. Process Biochem., 71: 31-40.
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  4. Osman, A., G. El-Didamony, M. Sitohy, M. Khalifa and G. Enan, 2016. Soybean glycinin basic subunit inhibits methicillin resistant-vancomycin intermediate Staphylococcus aureus (MRSA-VISA) in vitro. Int. J. Applied Res. Nat. Prod., 9: 17-26.
  5. Osman, A., E. Abbas, S. Mahgoub and M. Sitohy, 2016. Inhibition of Penicillium digitatum in vitro and in postharvest orange fruit by a soy protein fraction containing mainly β-conglycinin. J. General Plant Pathol., 82: 293-301.
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  6. Mahgoub, S.A., A.O. Osman and M.Z. Sitohy, 2016. Impeding Bacillus spore germination in vitro and in milk by soy glycinin during long cold storage. J. General Applied Microbiol., 62: 52-59.
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  7. El-Sayed, A.S., A.E. Hassan, A.A. Shindia, S.G. Mohamed and M.Z. Sitohy, 2016. Aspergillus flavipes methionine γ-lyase-dextran conjugates with enhanced structural, proteolytic stability and anticancer efficiency. J. Mol. Catal. B: Enzymat., 133: S15-S24.
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  8. El-Newary, S.A., A.M. Sulieman, S.R. El-Attar and M.Z. Sitohy, 2016. Hypolipidemic and antioxidant activity of the aqueous extract from the uneaten pulp of the fruit from Cordia dichotoma in healthy and hyperlipidemic Wistar albino rats. J. Nat. Med., 70: 539-553.
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  9. Abdel-Shafi, S., A. Osman, G. Enan, M. El-Nemer and M. Sitohy, 2016. Antibacterial activity of methylated egg white proteins against pathogenic G+ and G- bacteria matching antibiotics. SpringerPlus, Vol. 5. 10.1186/s40064-016-2625-3.
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  10. Sitohy, M., A. Osman, A. Abdel Ghany and A. Salama, 2015. Antibacterial phycocyanin from Anabaena oryzae SOS13. Int. J. Applied Res. Nat. Prod., 8: 27-36.
  11. Salama, A., A.A. Ghany, A. Osman and M. Sitohy, 2015. Maximising phycocyanin extraction from a newly identified Egyptian cyanobacteria strain: Anabaena oryzae SOS13. Int. Food Res. J., 22: 517-525.
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  12. Sitohy, M.Z., A.O. Osman and S.A. Mahgoub, 2014. Bioactive proteins against pathogenic and spoilage bacteria. Funct. Foods Health Dis., 4: 451-462.
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  13. Osman, A.O., S.A. Mahgoub and M.Z. Sitohy, 2014. Hindering milk quality storage deterioration by mild thermization combined with methylated chickpea protein. Int. Food Res. J., 21: 693-701.
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  14. Osman, A., S. Mahgoub, R. El‐Masry and A. Al‐Gaby and M. Sitohy, 2014. Extending the technological validity of raw buffalo milk at room temperature by esterified legume proteins. J. Food Proces. Preserv., 38: 223-231.
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  15. El-Sayed, A.S., H. Ibrahim and M.Z. Sitohy, 2014. Co-immobilization of PEGylated Aspergillus flavipesl-methioninase with glutamate dehydrogenase: A novel catalytically stable anticancer consortium. Enzyme Microbial Technol., 54: 59-69.
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  16. Abdulla, G., G.A. El-Shourbagy and M.Z. Sitohy, 2014. Effect of pre-drying, blanching and citric acid treatments on the quality of fried sweet potato chips. Am. J. Food Technol., 9: 39-48.
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  17. Sitohy, M., S. Mahgoub, A. Osman, R. El-Masry and A. Al-Gaby, 2013. Extent and mode of action of cationic legume proteins against listeria monocytogenes and salmonella enteritidis. Probio. Antimic. Prot., 5: 195-205.
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  18. Sitohy, M., A. Osman, A. Gharib, J.M. Chobert and T. Haertle, 2013. Preliminary assessment of potential toxicity of methylated soybean protein and methylated β-lactoglobulin in male Wistar rats. Food Chem. Toxicol., 59: 618-625.
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  19. Osman, A.O., S.A. Mahgoub and M.Z. Sitohy, 2013. Preservative action of 11S (glycinin) and 7S (β-conglycinin) soy globulin on bovine raw milk stored either at 4 or 25 C. J. Dairy Res., 80: 174-183.
  20. Mahgoub, S.A., M.Z. Sitohy and A.O. Osman, 2013. Counteracting recontamination of pasteurized milk by methylated soybean protein. Food Bioprocess Technol., 6: 101-109.
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  21. Mahgoub, S. and M. Sitohy, 2013. Comparative prevalence of pathogenic and spoilage microbes in chicken sausages from Egypt and Greece. Health, 5: 274-284.
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  22. Sitohy, M.Z., S.A. Mahgoub and A.O. Osman, 2012. In vitro and in situ antimicrobial action and mechanism of glycinin and its basic subunit. Int. J. Food Microbial., 154: 19-29.
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  23. Sitohy, M.Z. and A.O. Osman, 2011. Enhancing milk preservation with esterified legume proteins. Probiot. Antimicrob. Prot., 3: 48-56.
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  24. Sitohy, M., S. Mahgoub and A. Osman, 2011. Controlling psychrotrophic bacteria in raw buffalo milk preserved at 4°C with esterified legume proteins. LWT-Food Sci. Technol., 44: 1697-1702.
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  25. Mahgoub, S., A. Osman and M. Sitohy, 2011. Inhibition of growth of pathogenic bacteria in raw milk by legume protein esters. J. Food Protect., 74: 1475-1481.
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  26. Hamad, E.M., S.H. Taha, A.G. Abou Dawood, M.Z. Sitohy and M. Abdel-Hamid 2011. Protective effect of whey proteins against nonalcoholic fatty liver in rats. Lipids Health Dis., Vol. 10 .
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  27. El-Ghaish, S., I. Hadji-Sfaxi, A. Ahmadova, Y. Choiset and H. Rabesona et al., 2011. Characterization of two safe Enterococcus strains producing enterocins isolated from Egyptian dairy products. Benef. Microb., 2: 15-27.
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  28. El-Ghaish, S., H. Rabesona, Y. Choiset, M. Sitohy, T. Haertle and J.M. Chobert, 2011. Proteolysis by Lactobacillus fermentum IFO3956 isolated from Egyptian milk products decreases immuno-reactivity of α S1-casein. J. Dairy Res., 78: 203-210.
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  29. El-Ghaish, S., A. Ahmadova, I. Hadji-Sfaxi, K.E. El Mecherfi and I. Chostiy, 2011. Potential use of lactic acid bacteria for reduction of allergenicity and for longer conservation of fermented foods. Trends Food Sci. Technol., 22: 509-516.
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  30. Abd El-Salam, A.S.M., M.A. Doheim, M.Z. Sitohy and M.F. Ramadan, 2011. Deacidification of high-acid olive oil. J. Food Process Technol., Vol. S5. 10.4172/2157-7110.S5-001.
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  31. Taha, S.H., M.A. Mehrez, M.Z. Sitohy, A.G. Dawood, M.M. Abd-El Hamid and W.H. Kilany, 2010. Effectiveness of esterified whey proteins fractions against Egyptian Lethal Avian Influenza A (H5N1). Virol. J., 7: 330-335.
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  32. Sitohy, M.Z., M.M. Rashad, S.F. Sharobeem, A.E. Mahmoud, M.U. Nooman and A S. Al Kashef, 2010. Bioconversion of soy processing waste for production of surfactants. African J. Microbiol. Res., 4: 2811-2821.
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  33. Sitohy, M., M. Scanu, B. Besse, C. Mollat, S. Billaudel, T. Haertle and J.M. Chobert, 2010. Influenza virus A subtype H1N1 is inhibited by methylated β-lactoglobulin. J. Dairy Res., 77: 411-418.
  34. Sitohy, M. and A. Osman, 2010. Antimicrobial activity of native and esterified legume proteins against Gram-negative and Gram-positive bacteria. Food Chem., 120: 66-73.
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  35. Rashad, M.M., M.Z. Sitohy, S.F. Sharobeem, A.E. Mahmoud, M.U. Nooman and A.S. Al-Kashef, 2010. Production, purification and characterization of extracellular protease from Candida guilliermondii using okara as a substrate. Adv. Food Sci., 32: 100-109.
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  36. El-Ghaish, S., M. Dalgalarrondo, Y. Choiset, M. Sitohy, I. Ivanova, T. Haertle and J.M. Chobert, 2010. Screening of strains of Lactococci isolated from Egyptian dairy products for their proteolytic activity. Food Chem., 120: 758-764.
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  37. El-Ghaish, S., M. Dalgalarrondo, Y. Choiset, M. Sitohy, I. Ivanova, T. Haertle and J.M. Chobert, 2010. Characterization of a new isolate of Lactobacillus fermentum IFO 3956 from Egyptian Ras cheese with proteolytic activity. Eur. Food Res. Technol., 230: 635-643.
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  38. Besse, S. and T. Billaudel, 2010. Antiviral action of methylated b-lactoglobulin on the human influenza virus a subtype H3N2. Mahmoud Sitohy, B. Haertle J-M ChobertProbiotics Antimicro. Prot, 2: 104-111.
  39. Abdelbacki, A.M., S.H. Taha, M.Z. Sitohy, A.I.A. Dawood, M.M. Abd-El Hamid and A.A. Rezk, 2010. Inhibition of tomato yellow leaf curl virus (TYLCV) using whey proteins. Virol. J., Vol. 7. .
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  40. Sitohy, M., M. Dalgalarrondo, M. Nowoczin, B. Besse, S. Billaudel, T. Haertle and J.M. Chobert, 2008. The effect of bovine whey proteins on the ability of poliovirus and Coxsackie virus to infect Vero cell cultures. Int. Dairy J., 18: 658-668.
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  41. Ramadan, M.F., M.Z. Sitohy and J.T. Moersel, 2008. Solvent and enzyme-aided aqueous extraction of goldenberry (Physalis peruviana L.) pomace oil: Impact of processing on composition and quality of oil and meal. Eur. Food Res. Technol., 226: 1445-1458.
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  42. Sitohy, M., S. Billaudel, T. Haertle and J.M. Chobert, 2007. Lactoglobulin against Herpes simplex Virus type 1. comparison with the effect of acyclovir and L-polylysines. J. Agric. Food Chem., 55: 10214-10220.
  43. Sitohy, M., M. Doheim and H. Badr, 2007. Isolation and characterization of a lectin with antifungal activity from Egyptian Pisum sativum seeds. Food Chem., 104: 971-979.
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  44. El Sohaimy, S.A., M.Z. Sitohy and R.A. El-Masry, 2007. Isolation and partial characterization of chickpea, lupin and lentil seed proteins. World J. Agric. Sci., 3: 123-129.
  45. Chobert, J.M., M. Sitohy, S. Billaudel, M. Dalgalarrondo and T. Haertle, 2007. Anticytomegaloviral activity of esterified milk proteins and L-polylysines. J. Mol. Microbial. Biotechnol., 13: 255-258.
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  46. Sitohy, M., J.M. Chobert, U. Karwowska, A. Gozdzicka-Jozefiak and T. Haertle, 2006. Inhibition of bacteriophage M13 replication with esterified milk proteins. J. Agric. Food Chem., 54: 3800-3806.
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  47. Jean-Marc, C., S. Mahmoud, E.Z. Khaled, D. Michele, C. Yvan and H. Thomas, 2006. Study of conformational changes of ewe's holo (native) and apo-α-lactalbumin by spectroscopy and trypsinolysis. J. Food Biochem., 30: 390-404.
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  48. Sitohy, M., J.M. Chobert and T. Haertle, 2005. Esterified whey proteins can protect Lactococcus lactis against bacteriophage infection. Comparison with the effect of native basic proteins and L-polylysines. J. Agric. Food Chem., 53: 3727-3734.
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  49. El-Zahar, K., M. Sitohy, Y. Choiset, F. Metro, T. Haertle and J.M. Chobert, 2005. Peptic hydrolysis of ovine-lactoglobulin and-lactalbumin. Exceptional susceptibility of-lactoglobulin to pepsinolysis. Int. Dairy J., 15: 17-27.
  50. Chobert, J.M., K. El-Zahar, M. Sitohy, M. Dalgalarrondo, F. Metro, Y. Choiset and T. Haertle, 2005. Angiotensin I-converting-enzyme (ACE)-inhibitory activity of tryptic peptides of ovine $\ beta $-lactoglobulin and of milk yoghurts obtained by using different starters. Le Lait, 85: 141-152.
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  51. El-Zahar, K., M. Sitohy, M. Dalgalarrondo, Y. Choiset, F. Metro, T. Haertle and J.M. Chobert, 2004. Purification and physico-lactalbumin. Mol. Nutr. Food Res., 48: 177-183.
  52. El-Zahar, K., M. Sitohy, M. Dalgalarrondo, Y. Choiset, F. Metro, T. Haertle and J.M. Chobert, 2004. Antimicrobial activity of ovine whey protein peptic hydrolysates. Milchwissenschaft, 59: 653-656.
  53. El‐Zahar, K., J. Chobert, M. Dalgalarrondo, M. Sitohy and T. Haertle, 2004. Proteolysis of ewe's caseins and whey proteins during fermentation of yogurt and storage. Effect of the starters used. J. Food Biochem., 28: 319-335.
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  54. El-Zahar, K., J.M. Chobert, M. Sitohy, M. Dalgalarrondo and T. Haertle, 2003. Proteolytic degradation of ewe milk proteins during fermentation of yoghurts and storage. Nahrung/Food, 47: 199-206.
  55. Sitohy, M., J. Chobert, J.C. Gaudin, T. Renac and T. Haertle, 2002. When positively charged milk proteins can bind to DNA. J. Food Biochem., 26: 511-532.
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  56. Sitohy, M.Z., J.M. Chobert, M. Schmidt, A. Gozdzicka-Jozefiak and T.J. Haertle, 2001. Interactions between basified whey proteins (esterified-lactoglobulin) and DNA studied by differential spectroscopy. J. Protein Chem., 20: 633-640.
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  57. Sitohy, M.Z., J.M. Chobert, M. Dalgalarrondo and T. Haertle, 2001. Factors influencing pepsinolysis of methyl-, ethyl-, and propyl-esters of β-lactoglobulin. J. Food Biochem., 25: 181-198.
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  58. Sitohy, M.Z., J.M. Chobert and T. Haertle, 2001. Peptic hydrolysis of methyl-, ethyl- and propyl-esters of β-casein and β-lactoglobulin. Milchwissenschaft, 56: 303-307.
  59. Sitohy, M.Z. and M.F. Ramadan, 2001. Degradability of different phosphorylated starches and thermoplastic films prepared from corn starch phosphomonoesters. Starch-Starke, 53: 317-322.
  60. Sitohy, M., J.M. Haertle and T. Chobert, 2001. Susceptibility to trypsinolysis of esterified milk proteins. Int. J.Biol. Macromol., 28: 263-271.
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  61. Sitohy, M., J.M. Chobert, J.C. Gaudin and T. Haertle, 2001. Esterified milk proteins inhibit DNA replication in vitro. Int. J. Boil. Macromol., 29: 259-266.
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  62. Sitohy, M., J.M. Chobert and T. Haertle, 2001. Study of the formation of complexes between DNA and esterified dairy proteins. Int. Dairy J., 11: 873-883.
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  63. Sitohy, M., J.M. Chobert and T. Haertle, 2001. Simplified short-time method for the esterification of milk proteins. Volkswirtschaftlicher Verlag, 56: 127-131.
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  64. Sitohy, M., J.M. Chobert and T. Haertle, 2001. Improvement of solubility and of emulsifying properties of milk proteins at acid pHs by esterification. Food/Nahrung, 45: 87-93.
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  65. El‐Zoghbi, M. and M.Z. Sitohy, 2001. Mineral absorption by albino rats as affected by some types of dietary pectins with different degrees of esterification. Food/Nahrung, 45: 114-117.
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  66. Sitohy, M.Z., S.S. El-Saadany, M.F. Ramadan and S.M. Labib, 2000. Physicochemical properties of different types of starch phosphate monoesters. Starch-Starke, 52: 101-105.
  67. Sitohy, M.Z., J.M. Chobert and T. Haertle, 2000. Study of factors influencing protein esterification reaction using β- lactoglobulin as a model. J.Food Biochem., 24: 381-398.
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  68. Sitohy, M.Z. and M.F. Ramadan 2000. Granular properties of different starch types as phosphorylated with mono and di-sodium hydrogen orthophosphate to monoester forms. Starch, 53: 27-34.
  69. Sitohy, M.Z., S.M. Labib, S.S. El-Saadany and M.F. Ramadan, 2000. Optimising the conditions for starch dry phosphorylation with sodium mono-and dihydrogen orthophosphate under heat and vacuum. Starch-Stuttgart, 52: 95-100.