Dr. Petra Obioma Nnamani
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Dr. Petra Obioma Nnamani

Professor
University of Nigeria, Nigeria

Highest Degree
Ph.D. in Pharmaceutics from University of Nigeria, Nsukka, Nigeria

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Biography

Dr. Petra Obioma Nnamani is currently Humboltian at HIPS, Saarland University, Germany, and also Senior lecturer (HEAD) at the Department of Pharmaceutics, University of Nigeria, Nsukka (UNN). She obtained her B.Pharm in 2001 and M.Pharm in 2004 both from UNN. During her Ph.D 2006-2010, Petra joined the nanotechnology group at ICS-UNIDO in Trieste, Italy (2009) for Early Research Training in Nanotechnology. She obtained her PhD in Drug Delivery in 2010 from UNN. She was awarded CV Raman International Fellowship for African Researchers at the Department of Physics, Shivaji University, Kolhapur, India in 2012. Following a competitive application process, in 2012 she was awarded the TWAS-DFG Cooperation Visits Programme to Helmholtz-Institute for Pharmaceutical Research Saarland, Saarland University, Saarbrücken, Germany in 2013.

Petra is a Member of the New York Academy of Sciences, Organization for Women in Science for the Developing World (OWSD) and Pharmaceutical Society of Nigeria. She is co-author of over 60 original papers and reviewer for a number of top journals. She has attended well over 30 international conferences with over 32 contributions. She is recipient of several awards: TechWomen USA (2017); Stars in Global Health Round 4 Phase 1 Award (Ref. 0251-01) by the Grand Challenges Canada on “using Moringa oleifera as a low-cost point-of-use (POU) treatment of drinking water in South East Nigeria. This recent innovation was patented in Nigeria, as the second patent registered by Petra. She has other on-going grant works funded by TETFund Nigeria. For TechWome 2017, she was 1 out of 5 selected among 1700 Nigerian Women applicants from a global pool of 4000 women in STEM from Asia, Middle East and Africa; hence an alumnus of TechWomen USA in 2017.

The research lines of Petra are focused on development and characterization of biocompatible and biodegradable systems for drug delivery (antimalarial and antibiotics etc) involving micro and nanoparticle systems as well as macro-systems (polymeric films) for buccal mucosa and wound healing applications. As co-coordinator of Public Health & Environmental Sustainability (PHES) Research Group, translational researches from lab-to-bed side in curing diseases such as ulcer, inflammation, infection...etc, are of interest.

Area of Interest:

Pharmaceutics
100%

Research Publications in Numbers

Books
1
Chapters
15
Articles
54
Abstracts
1

Selected Publications

  1. Uzondu, S., A. Echezona, C. Nwagwu, A. Onugwu and L. Ugorji et al., 2022. Combating Antimalarial Drug Resistance: Recent Advances and Future Perspectives. In: Malaria-Recent Advances and New Perspectives, Piccaluga, P.P. (Ed.), IntechOpen, London.
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  2. Onugwu, A.L., A.A. Attama, P.O. Nnamani, S.O. Onugwu, E.B. Onuigbo and V.V. Khutoryanskiy, 2022. Development and optimization of solid lipid nanoparticles coated with chitosan and poly(2-ethyl-2-oxazoline) for ocular drug delivery of ciprofloxacin. J. Drug Delivery Sci. Technol., Vol. 74. 10.1016/j.jddst.2022.103527.
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  3. Nnamani, P., N. Ogechukwu, A. Odo, V. Abimibola and A. Ugwu et al., 2022. Gentamicin nanogel films based on carrageenan-Prosopis africana for improved wound healing. Precis. Nanomed., 5: 879-896.
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  4. Attah, A.F., O.O. Akindele, P.O. Nnamani, U.J. Jonah, M.A. Sonibare and J.O. Moody, 2022. Moringa oleifera seed at the interface of food and medicine: Effect of extracts on some reproductive parameters, hepatic and renal histology. Front. Pharmacol., Vol. 13. 10.3389/fphar.2022.816498.
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  5. Onugwu, A.L., C.P. Agbo, C.S. Nwagwu, S.E. Uzondu and A.C. Echezona et al. 2021. Development of Lipid-Based Microsuspensions for Improved Ophthalmic Delivery of Gentamicin Sulphate. Therapeutic Delivery 10.4155/tde-2021-0039.
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  6. Nzekwe, I.T., O.I. Agwuka, M.U. Okezie, D.O. Fasheun, P.O. Nnamani and C.O. Agubata, 2021. Designing an ideal alcohol-based hand sanitizer: In vitro antibacterial responses of ethanol and isopropyl alcohol solutions to changing composition. AAPS Open, Vol. 7. 10.1186/s41120-021-00038-x.
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  7. Nnamani, P.O., F.C. Kenechukwu, C.S. Nwagwu, O. Okoye and A.A. Attama 2021. Physicochemical Characterization of Artemether-Entrapped Solid Lipid Microparticles Prepared from Templated-Compritol and Capra hircus (Goat Fat) Homolipid. Dhaka Univ. J. Pharm. Sci. 20: 67-80.
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  8. Nnamani, P.O., E.C. Ibezim, M.U. Adikwu and A.A. Attama, 2021. Sustained-release glibenclamide-loaded solid lipid microparticles from micellar solutions of homolipids. J. Pharm. Innovation, 10.1007/s12247-021-09554-5.
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  9. Nnamani, P.O., A.A. Ugwu, O.H. Nnadi, F.C. Kenechukwu, K.C. Ofokansi, A.A. Attama and C.M. Lehr, 2021. Formulation and evaluation of transdermal nanogel for delivery of artemether. Drug Delivery Transl. Res., 10.1007/s13346-021-00951-4.
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  10. Kola-Mustapha, A. and M. Ilomuanya 2021. The Covid-19 Response in Nigeria: Adequate Protection of a Fragile Healthcare Delivery System. NJP 55: 13-19.
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  11. Kenechukwu, F.C., M.A. Momoh, P.O. Nnamani, C.E. Umeyor and E.M. Uronnachi et al. 2021. Dual-Responsive Micellar Microgels Matrixed with Surface-Engineered Lipids: a New Approach for Controlled Vaginal Drug Delivery. J. Pharm. Innov. 10.1007/s12247-021-09546-5.
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  12. Nnamani, P.O., A.C. Echezona, O.C. Metu, S.U. Onoja and J.D.N. Ogbonna et al., 2020. Formulation and characterization of artemether-loaded sodium alginate microcapsules. Trop. J. Pharm. Res., 19: 1341-1349.
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  13. Nnamani, P., O. Nnadi, E. Ibezim, E. Ayogu, J. Reginald-Opara, S. Onoja, A. Odo, A. Ugwu, C. Ogbonna and A. Attama, 2020. In vivo antiplasmodial potential of Carrageenan and Prosopis africana buccal films of artemether on malariogenic mice, J. Drug Delivery Ther., 10: 114-125.
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  14. Nnamani P.O., F.C. Kenechukwu, F.O. Asogwa, M.A. Momoh, Claus-Michael. Lehr, A.A. Attama, 2020. Novel anti-ulcer phytosomal formulation of ethanol extract of pentaclethra macrophylla stem-bark. Tropical Journal of Natural Product Research 4: 385-391.
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  15. Nnamani, P., A. Ugwu, E. Ibezim, S. Onoja and A. Odo et al., 2019. Preparation, characterisation and in vitro antibacterial property of ciprofloxacin-loaded nanostructured lipid carrier for treatment of Bacillus subtilis infection. J. Microencapsulation, 36: 32-42.
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  16. Attah, A.F., J.O. Moody, M.A. Sonibare, H.H. Salahdeen, O.O. Akindele, P.O. Nnamani, O.A. Diyaolu and Y. Raji, 2019. Aqueous extract of Moringa oleifera leaf used in Nigerian ethnomedicine alters conception and some pregnancy outcomes in Wistar rat. South Afr. J. Botany, 129: 255-262.
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  17. Kenechukwu, F.C., A.A. Attama, E.C. Ibezim, P.O. Nnamani, C.E. Umeyor, E.M. Uronnachi, M.A. Momoh, P.A. Akpa and A.C. Ozioko, 2018. Novel intravaginal drug delivery system based on molecularly PEGylated lipid matrices for improved antifungal activity of miconazole nitrate. BioMed. Res. Int., 2018: 1-18.
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  18. Kenechukwu, F.C., A.A. Attama, E.C. Ibezim, P.O. Nnamani and C.E. Umeyor et al., 2018. Surface-modified mucoadhesive microgels as a controlled release system for miconazole nitrate to improve localized treatment of vulvovaginal candidiasis. Eur. J. Pharm. Sci., 111: 358-375.
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  19. Kenechukwu, F.C., A.A. Attama, E.C. Ibezim, P.O. Nnamani, C.E. Umeyor, E.M. Uronnachi, M.A. Momoh and P.A. Akpa, 2017. Tailor-made mucoadhesive lipid nanogel improves oromucosal antimycotic activity of encapsulated miconazole nitrate. Eur. J. Nanomed., 9: 115-126.
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  20. Otuu, C.C., S.I. Inya-Agha, P.O. Nnamani, F.C. Kenechukwu, A.A. Attama, 2015. Cyanide content of well water round- about cassava processing plants in enugu, south-eastern, nigeria. Int. J. Environ. Biol., 4: 10-12.
  21. Nnamani, P.O., E.U. Dibua, F.C. Kenechukwu, C.C. Ogbonna, C. Onyemaechi and A.A. Atttama, 2015. Novel lipid-based dermal microgels of neobacin�. Afr. J. Biotechnol., 14: 979-989.
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  22. Nnamani, P.O., S. Hansen, M. Windbergs and C.M. Lehr, 2014. Development of artemether-loaded nanostructured lipid carrier (nlc) formulation for topical application. Int. J. Pharma., 477: 208-217.
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  23. Nnamani, P.O., F.C. Kenechukwu, C.L. Anugwolu and A.A. Attama, 2014. Evaluation of hydrogels based on poloxamer 407 and polyacrylic acids for enhanced topical activity of gentamicin against susceptible infections. Trop. J. Pharma. Res., 13: 1385-1391.
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  24. Nadaf, S., P. Nnamani and N. Jadhav, 2014. Evaluation of prosopis africana seed gum as an extended release polymer for tablet formulation. AAPS Pharm. Sci. Tech., 16: 716-729.
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  25. Momoh, M.A., F.C. Kenechukwu, P.O. Nnamani and J.C. Umetiti, 2014. Influence of magnesium stearate on the physicochemical and pharmacodynamic characteristics of insulin-loaded Eudragit entrapped mucoadhesive microspheres. Drug Delivery, 10.3109/10717544.2014.898108.
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  26. Kenechukwu, F.C., M.A. Momoh, P.O. Nnamani and A.A. Attama, 2014. Solid lipid micro-dispersions (slms) based on pegylated solidified reverse micellar solutions (srms): a novel carrier system for gentamicin. Drug Delivery, 10.3109/10717544.2014.900152.
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  27. Kenechukwu, F.C., C.E. Umeyor, M.A. Momoh, J.D.N. Ogbonna, S.A. Chime, P.O. Nnamani, and A.A. Attama, 2014. Evaluation of gentamicin-entrapped solid lipid microparticles formulated with a biodegradable homolipid from capra hircus. Trop. J. Pharma. Res., 13: 1199-1205.
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  28. Kenechukwu, F.C, M.A. Momoh, P.O. Nnamani, J.D.N. Ogbonna, C.E. Umeyor, and A.A. Attama, 2014. Improved bioactivity of gentamicin from novel solid lipid microparticles based on beeswax. Nig. J. Pharm. Res., 10: 35-45.
  29. Nnamani, P.O., F.C. Kenechukwu, E.U. Dibua, C.C. Ogbonna, U.L. Monemeh and A.A. Attama, 2013. Transdermal microgels of gentamicin. Eur. J. Pharma. Biopharm., 84: 345-354.
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  30. Nnamani, P.O., F.C. Kenechukwu, E.U. Dibua, C.C. Ogbonna, M.A. Momoh, J. D.N. Ogbonna and A.A. Attama, 2013. Bioactivity of gentamicin contained in novel transdermal drug delivery systems (tdds) formulated with biodegradable polyesters. Afr. J. Pharm. Pharmacol., 7: 1987-1993.
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  31. Nnamani, P.O., F.C. Kenechukwu, E.U. Dibua, C.C. Ogbonna, M.A. Momoh, A.U. Olisemeka and A. Chukwuma, 2013. Formulation, characterization and ex-vivo permeation studies on gentamicin-loaded transdermal patches based on PURASORB� polymers. Sci. Res. Essays, 8: 973-982.
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  32. Nnamani, P.O., F.C. Kenechukwu, E.U. Dibua, C.C. Ogbonna and M.A. Momoh et al., 2013. Novel transdermal patches for controlled delivery of gentamicin: formulation, characterization and in vitro release properties. J. Pharm. Res., .
  33. Nnamani, P.O., F.C. Kenechukwu, C.L. Anugwolu, A.C. Obumneme and A.A. Attama, 2013. Characterization and controlled release of gentamicin from novel hydrogels based on poloxamer 407 and polyacrylic acids. Afr. J. Pharm. Pharmacol., 7: 2540-2552.
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  34. Nnamani, P. O., A.A. Attama, C.F. Kenechukwu, C.E. Ibezim and U.M. Adikwu, 2013. Pharmacodynamics of piroxicam from novel solid lipid microparticles formulated with homolipids from Bos indicus. Curr. Drug Delivery, 10: 645-655.
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  35. Kenechukwu, F.C., E.C. Ibezim, A.A. Attama, M.A. Momoh, J.D.N. Ogbonna, P.O. Nnamani and E.M. Uronnachi, 2013. Preliminary spectroscopic characterization of pegylated mucin, a novel polymeric drug delivery system. Afr. J. Biotechnol., 12: 6661-6671.
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  36. Nnamani, P.O., F.C. Kenechukwu, O.C. Chika and F.C. Otuu, 2012. Performance of prosopis africana peel powder (papp) as a novel sorbent for remediating malachite green contaminated aqua system. Sci. Res. Essays, 7: 4130-4137.
  37. Nnamani, P.O., F.C. Kenechukwu and W.N. Oguamanam, 2012. Cardiospermum grandiflorum leaf extract potentiates amoxocillin activity of staphylococcus aureus. J. Med. Plants Res., 6: 901-905.
  38. Nnamani, P.O., C.C. Ogbonna, E.U. Dibua, N.N. Ezedigboh and A.A. Attama, 2012. Sustained circulation time of glibenclamide from pegylatedsolid lipid microparticles. Int. J. Novel Drug Deliv. Tech., 2: 283-290.
  39. Nnamani P.O., N.J. Nwodo and S. Giacinto, 2012. Preliminary characterization of n-trimethylchitosan as a nanocarrier for malarie vaccine. Journal of Cheminformatics 4: 47-47.
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  40. Uju, D.E and N.P. Obioma, 2011. Anticariogenic potentials of clove, tobacco and bitter kola. Asian Pacif. J. Trop. Med., 4: 814-818.
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  41. Nnamani, P.O., G. Scoles and S. Krol, 2011. Preliminary characterization of n-trimethylchitosan as a nanocarrier for malaria vaccine. J. Vector Borne Dis., 48: 224-230.
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  42. Nnamani, P.O., F.C. Kenechukwu and R. Okwor, 2011. Volatile oil a possible antibiotic constituent of the leaves of ocimum gratissimum. Plant Prod. Res. J., 15: 36-41.
  43. Nnamani, P.O., 2011. Caco3 microparticles: formulation, preparation, characterization, release of bio-molecules and applications. Nig. J. Pharm. Res., 9: 55-77.
  44. Amuta, O.P., P.O. Nnamani and A.D. Musa, 2011. Three pyridinium alkaloids may account for the antibiotic effect of the seed of abrus precatorius. Pelagia Res. Lib., 2: 42-45.
  45. Nnamani, P.O., C.O. Esimone and T.A. Eneh, 2006. An in vitro evaluation of antimicrobial interaction between glycine and some penicillins using the decimal assay for additivity (daa) method. J. Pharm.l Allied Sci., 3: 289-293.
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  46. Attama A.A. and P.O. Nnamani, 2005. The mechanism of diclofenac sodium release from non-disintegrating bioadhesive tablets. Journal of Pharmaceutical and Allied Sciences 10.4314/jophas.v2i2.34978 http://dx.doi.org/10.4314/jophas.v2i2.34978.
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