Dr. Orish Ebere Orisakwe
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Dr. Orish Ebere Orisakwe

Professor
Department of Experimental Pharmacology & Toxicology, Faculty of Pharmacy, University of Port Harcourt, Nigeria


Highest Degree
Ph.D. in Pharmacology from University of Port Harcourt, Nigeria

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Area of Interest:

Pharmacology and Toxicology
100%
Physiology
62%
Ethnopharmacology
90%
Drug Research
75%
Toxicology
55%

Research Publications in Numbers

Books
3
Chapters
16
Articles
260
Abstracts
38

Selected Publications

  1. Nduka, J.K. and O.E. Orisakwe, 2011. Water-quality issues in the Niger Delta of Nigeria: A look at heavy metal levels and some physicochemical properties. Environ. Sci. Pollut. Res., 18: 237-246.
    CrossRef  |  Direct Link  |  
  2. Orisakwe, O.E., H.C. Debem, E.U. Etuk and A.T. Elsa, 2010. Spermatoxic effects of operation sweep herbal supplement in male albino rats. J. Basic Clin. Physiol. Pharmacol., 21: 147-156.
    PubMed  |  
  3. Nonyelum, S.C., N. Nkem, C.N. Ifeyinwa and O.E. Orisakwe, 2010. Safety warnings and first aid instructions on consumer and pharmaceutical products in Nigeria: has there been an improvement? J. Pak. Med. Assoc., 60: 801-804.
  4. Nduka, J.K., O.E. Orisakwe and L.O. Ezenweke, 2010. Nitrate and nitrite levels of potable water supply in Warri, Nigeria: A public health concern. J. Environ. Health, 72: 28-32.
    PubMed  |  
  5. Nduka, J.K. and O.E. Orisakwe, 2010. Water quality issues in the Niger Delta of Nigeria: Polyaromatic and straight chain hydrocarbons in some selected surface waters. Water Qual. Exp. Health, 2: 65-74.
    CrossRef  |  
  6. Nduka, J.K. and O.E. Orisakwe, 2010. Precipitation chemistry and occurrence of acid rain over the oil-producing niger delta region of Nigeria. Sci. World J., 10: 528-534.
    PubMed  |  
  7. Kanayochukwu, N.J. and O.O. Ebere, 2010. Assessment of environmental distribution of lead in some municipal cities of South-Eastern Nigeria. Int. J. Envir. Res. Public Health, 7: 2501-2513.
    Direct Link  |  
  8. Frazzoli, C., O.E. Orisakwe, R. Dragone and A. Mantovani, 2010. Diagnostic health risk assessment of electronic waste on the general population in developing countries scenarios. Envir. Impact Assess. Rev., 30: 388-399.
  9. Orisakwe, O.E., and J.K. Nduka, 2009. Lead and cadmium levels of commonly administered pediatric syrups in Nigeria: A public health concern. Sci. Total Envir., 407: 5993-5996.
    PubMed  |  
  10. Orisakwe, O.E., C.I. Oragwu, J.M.U. Maduabuchi, C.N. Nzegwu and J.K.C. Nduka, 2009. Copper, selenium and zinc content of canned and non-canned beverages in Nigeria. Afr. J. Environ. Sci. Tech., 3: 42-49.
    Direct Link  |  
  11. Orisakwe, O.E., 2009. Environmental pollution and blood lead levels in Nigeria: Who is unexposed? Int. J. Occup. Environ. Health, 15: 315-317.
    PubMed  |  
  12. Nduka, J.K. and O.E. Orisakwe, 2009. Heavy metal hazards of pediatric syrups administration in Nigeria: A look at chromium, nickel and manganese. Int. J. Environ. Res. Public Health, 6: 1972-1979.
    CrossRef  |  
  13. Nduka, J.K. and O.E. Orisakwe, 2009. Effect of effluents from warri refinery petrochemical company WRPC on water and soil qualities of contiguous host and impacted on communities of Delta State, Nigeria. Open Environ. Pollut. Toxicol. J., 1: 11-17.
    CrossRef  |  Direct Link  |  
  14. Ezejiofor, N.A., C.N. Orish, O.A. Georgewill, V.I. Onyiorah and O.E. Orisakwe, 2009. Hepatotoxic and hematologic effects of an aqueous extract of the Nigerian herbal remedy U&D Sweet Bitter in male albino rats. J. Basic. Clin. Physiol. Pharmacol., 20: 179-186.
    PubMed  |  
  15. Nriagu, J., M. Afeiche, T. Arowolo, G. Ana and M.K.C. Sridhar et al., 2008. Lead poisoning associated with malaria in children of urban areas of Nigeria. Int. J. Hyg. Environ. Health, 211: 591-605.
    PubMed  |  
  16. Nduka, J.K.C., O.E. Orisakwe, L.O. Ezenweke, T.E. Ezenwa, M.N. Chendo and N.G. Ezeabasili, 2008. Acid rain phenomenom in the Niger Delta Region of Nigeria: Economic, Biodiversity and Public Health Concern. Sci. World J., 8: 811-818.
    Direct Link  |  
  17. Nduka, J.K.C., O.E. Orisakwe and C.A. Maduawguna, 2008. Lead levels in paint flakes from buildings in Nigeria: A preliminary study. Toxicol. Ind. Health, 24: 539-542.
    CrossRef  |  
  18. Nduka, J.K., O.E. Orisakwe, L.O. Ezenweke, M.N. Chendo and T.E. Ezenwa, 2008. Heavy metal contamination of foods by refuse dump sites in Awka, Southeastern Nigeria. Scientific World J., 8: 941-948.
    PubMed  |  
  19. Nduka, J.K., O.E. Orisakwe and L.O. Ezenweke, 2008. Some physicochemical parameters of potable water supply in Warri, Niger Delta area of Nigeria. Sci. Res. Essay, 3: 547-551.
    Direct Link  |  
  20. Maduabuchi, J.M.U., C.N. Nzegwu, E.O. Adigba, C.I. Oragwu and F.N. Agbo et al., 2008. Iron, manganese and nickel exposure from beverages in Nigeria: A public health concern?. J. Health Sci., 34: 335-338.
    Direct Link  |  
  21. Ilo, C.E., N.A. Ezejiofor, N. Agbakoba, S.A. Brown, C.A. Maduagwuna, P.U. Agbasi, O.E. Orisakweph, 2008. Effect of Chloroquine on the urinary excretion of ciprofloxacin. Amer. J. Therap., 15: 419-422.
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  22. Ezejiofor, N.A., N. Maduagwuna, O.V. Igwebuike, D.C. Hussaini and O.E. Orisakwe, 2008. Nephrotoxic effects of aquoeus extract of U and Dee Sweet Bitter (a Nigerian Herbal Remedy) in male albino rats. J. Basic Clin. Physiol. Pharmacol., 19: 151-158.
    Direct Link  |  
  23. Ezejiofor, N.A., C. Maduagwunan, V.I. Onyiaorah, D.C. Hussaini and O.E. Orisakwe, 2008. Multiple organ toxicity of a Nigerian herbal supplement (U & D Sweet Bitter) in male albino rats. Pak. J. Pharm. Sci., 21: 426-429.
    Direct Link  |  
  24. Orisakwe, O.E., E. Nwachukwu, H.B. Osadolor, O.J. Afonne and C.E. Okocha, 2007. Liver and kidney function tests amongst paint factory workers in Nkpor, Nigeria. Toxicol. Ind. Health, 23: 161-165.
    CrossRef  |  
  25. Nduka. J.K.C., O.E. Orisakwe, L.O. Ezenweke, C.O. Abiakam, C.K. Nwanguma and J.M.U. Maduabuchi, 2007. Metal contamination and infiltration into the soil at refuse dump sites in Awka, Nigeria. Arch. Environ. Health, 61: 197-204.
    CrossRef  |  
  26. Nduka, J.K.C. and O.E. Orisakwe, 2007. Heavy metal levels and physico-chemical quality of potable water supply in warri, Nigeria. Annali Chimica, 97: 867-874.
    CrossRef  |  PubMed  |  
  27. Nduka, J.K., O.E. Orisakwe and C.A. Maduawguna, 2007. Heavy metals other than lead in flaked paints from buildings in Eastern Nigeria. Toxicol. Ind. Health, 23: 525-528.
    PubMed  |  
  28. Maduabuchi, J.M.U., C.N. Nzegwu, E.O. Adigba, R.U. Aloke, C.N. Ezomike and O.E. Orisakwe, 2007. Arsenic, selenium and zinc exposures from canned and non- canned beverages in Nigeria: A public health concern. Int. J. Env. Res. Pub Health, 4: 28-33.
  29. Chiroma, H.D., G.T. Ayinla, O.E. Orish, O.O. Emmanuel and A.A. Jigam et al., 2007. Seasonal nitrate content of stream water, soil and some Foodstuffs samples in Abuja municipal area of Federal Capital Territory,Nigeria. J. Health Sci., 53: 359-364.
    Direct Link  |  
  30. Olife, I.C., A.N. Okaka, C.E. Dioka, S.C. Meludu and O.E. Orisakwe, 2007. Iodine status and the effect of soil erosion on trace elements in nanka and oba towns of anambra state, Nigeria. Annali Chim., 97: 895-903.
    CrossRef  |  
  31. Orisakwe, O.E., I.O. Igwilo, O.J. Afonne and U.J.M. Maduabuchi, 2006. Heavy metal hazards of Nigerian sachet water. Arch. Environ. Health, 61: 209-313.
  32. Orisakwe, O.E., 2006. Labeling and certification on commonly consume beverages in Nigeria: Are they Adequate. World J. Med. Sci., 1: 56-58.
    Direct Link  |  
  33. Orisakwe O.E., E. Obi and D.N. Akunyili, 2006. Safety warnings and first aid instructions on Nigeria traditional herbal remedies: are they adequate. World J. Med. Sci., 1: 108-111.
  34. Obi, E., D.N. Akunyili, B.O. Ekpo and O.E. Orisakwe, 2006. Heavy metals hazards of Nigerian herbal remedies. Sci. Total Environ., 369: 35-41.
  35. Igwilo, I.O., J.O. Afonne, U.J. Maduabuchi and O.E. Orisakwe, 2006. Toxicological study of the Anam River in Otuocha, Anambra State, Nigeria. J. Arch. Environ. Occup. Health, 61: 205-208.
    CrossRef  |  PubMed  |  Direct Link  |  
  36. Elo, I.C., N.A. Ilondu, N. Okwoli, S.A. Brown and O.E. Orisakwe, 2006. Effect of Chloroquinine on bioavailability of ciprofloxacin in humans. Amer. J. Therap., 13: 432-435.
  37. Orisakwe, O.E., D.D. Akumka, A.A. Njan, O.J. Afonne and O.O. Okechi, 2005. Hepatotoxic and haematologic effects of Nigerian bonny light crude oil in male albino rats. Toxicol. Environ. Chem., 87: 215-221.
    CrossRef  |  Direct Link  |  
  38. Maduabuchi, J.M.U., C.N. Nzegwu, E.O. Adigba, R.U. Aloke and C.N. Ezomike et al., 2005. Lead and Cadmium exposures from canned and non-canned beverages in Nigeria: A public health concern. Sci. Total Environ., 336: 621-626.
    CrossRef  |  
  39. Asomugha, R., O.E. Orisakwe, O.J. Afonne, E. Obi, J.C. Nduka and C.E. Dioka, 2005. Impact of effluents from cable manufacturing plant on food, water and soil qualities in nnewi, Nigeria. Pak. J. Biol. Sci., 8: 744-747.
    CrossRef  |  Direct Link  |  
  40. Orisakwe, O.E., R. Asomugha, O.J. Afonne, C.N. Anisi, E. Obi and C.E. Dioka, 2004. Impact of effluents from a car battery manufacturing plant in Nigeria on water, soil, and food qualities. Arch. Environ. Health, 59: 31-36.
    PubMed  |  
  41. Orisakwe, O.E., P.U. Agbasi, S.I. Ofoefule, N.A. Ilondu and O.J. Afonne et al., 2004. Effect of pefloxacin on the urinary excretion of rifampicin. Am. J. Therap., 11: 13-16.
  42. Orisakwe, O.E., O.J. Afonne, P.U. Agbasi and S.I. Ofoefule, 2004. Urinary excretion of rifampicin in the presence of ciprofloxacin. Am. J. Ther., 11: 171-174.
    PubMed  |  
  43. Orisakwe, O.E., D.N. Akunyili, P.U. Agbasi and N.A. Ezejiofor, 2004. Some plasma and saliva pharmacokinetics parameters of rifampicin in the presence of pefloxacin. Am. J. Ther., 11: 283-287.
    PubMed  |  
  44. Orisakwe, O.E., D.D. Akumka, A.A. Njan and O.J. Afonne, 2004. Testicular toxicity of Nigerian bonny light crude oil in male albino rats. Reprod. Toxicol., 18: 439-442.
    PubMed  |  
  45. Orisakwe, O.E., D.C. Husaini and O.J. Afonne, 2004. Testicular effects of sub-chronic administration of Hibiscus sabdariffa calyx aqueous extract in rats. Reprod. Toxicol., 18: 295-298.
    CrossRef  |  PubMed  |  Direct Link  |  
  46. Orisakwe, O.E., A.A. Njan, O.J. Afonne, D.D. Akumka, V.N. Orish and O.O. Udemezue, 2004. Investigation into the nephrotoxicity of Nigerian bonny light crude oil in Albino rats. Int. J. Environ. Res. Public Health, 1: 106-110.
    CrossRef  |  PubMed  |  Direct Link  |  
  47. Orisakwe O.E., D.D. Akumka, A.A. Njan and O.J. Afonne, 2004. Testicular toxicity of Nigerian bonny-light crude oil in male albino rats. Reprod. Toxicol., 18: 439-442.
    PubMed  |  
  48. Ofoefule, S.I., E.C. Ibezim, O.C. Esimone, M.N. Pepple, C.N. Njoku and E.O. Orisakwe, 2004. Bioavalability of metronidazole in rabbits after administration of rectal suppository. Amer. J. Ther., 11: 190-193.
    PubMed  |  
  49. Obi, E., O.E. Orisakwe., L.A. Asomugha, V.N. Orish, O.O. Udemezue and N.A. Ezejiofor, 2004. Hepatotoxicity of halofantrine in guinea pigs. Ind. J. Pharma., 36: 303-305.
    Direct Link  |  
  50. Hussaini, D.C., O.E. Orisakwe, A.A. Njan, D.D. Akumka and O.O. Udemezue, 2004. Subchronic administration of Nigerian specie of aqueous extract of Hibiscus sabdariffa calyx in rats did not produce cardiotoxicity. Eur. Bull. Drug Res., 12: 1-5.
  51. Dioka, C.E., O.E. Orisakwe, F.A.A. Adeniyi and S.C. Meludu, 2004. Liver and renal function tests in occupationally lead exposed artisans in mechanic village in Nnewi, Nigeria. Int. J. Environ. Res. Pub. Health, 1: 19-23.
  52. Orisakwe, O.E., O.J. Afonne, N.A. Ezejiofor and S. Tsalha, 2003. In vitro effects of sulphate cathartics on the adsorption of doxycycline to activated charcoal. Eur. Bull. Drug Res., 11: 93-98.
  53. Orisakwe, O.E., O.J. Afonne, M.A. Chude, E. Obi and C.E. Dioka, 2003. Subchronic toxicity studies of the aqueous extract of Boerhavia diffusa leaves. J. Health Sci., 49: 444-447.
    Direct Link  |  
  54. Orisakwe, O.E., E. Obi, O.O. Udemezue and S.C. Meludu, 2003. Effect of halofantrine on testicular architecture and testosterone level in guinea pigs. Eur. Bull. Drug Res., 11: 105-109.
  55. Orisakwe, O.E., D.C. Hussaini, V.N. Orish, E. Obi and O. Udemezue, 2003. Nephrotoxic effects of Hibiscus sabdariffa calyx in rats. Eur. Bull. Drug Res., 11: 99-104.
  56. Orisakwe, O.E., O.J. Afonne, N. Ilondu, E. Obi and C.S. Ufearo et al., 2002. Influence of prokinetics on the gastrointestinal transit and residence times of activated charcoal. J. Pak. Med. Assoc., 52: 354-356.
    PubMed  |  
  57. Orisakwe, O.E., O.J. Afonne, E.C. Dioka, P.U. Agbasi, C. Azikiwe and E. Obi, 2002. Testicular toxicity of rinbacin in rats. Biol. Pharm. Bull., 25: 206-208.
    Direct Link  |  
  58. Ofoefule, S.I., C.E. Obodo, O.E. Orisakwe, O.J. Afonne and N.A. Ilondu et al., 2002. Salivary and urinary excretion and plasma-saliva concentration ratio of isoniazid (INH) in the presence of co-administered ciprofloxation (CP). Am. J. Ther., 9: 15-18.
  59. Dioka, C., O.E. Orisakwe, O.J. Afonne, P.U. Agbasi, D.D. Akumka and C.J. Okonkwo, 2002. Investigation into the haematologic and hepatoxic effects of rinbacin in rats. J. Health Sci., 48: 393-398.
    Direct Link  |  
  60. Afonne, O.J., O.E. Orisakwe, S.I. Ofoefule, S. Tsalha, E. Obi, N.A. Ilondu and O. Okorie, 2002. Saline cathartics and adsorptive capacity of activated charcoal for doxycycline Acta. Poloniae Pharm. Drug Res., 59: 177-179.
    PubMed  |  
  61. Afonne, O.J., O.E. Orisakwe, E. Obi, C.E. Dioka and G.I. Ndubuka, 2002. Nephrotoxic actions of low-dose mercury in mice: Protection by zinc. Arch. Environ. Health., 57: 98 -102.
    PubMed  |  
  62. Afonne, O.J., O.E. Orisakwe, C.E. Dioka, G.I. Ndubuka, U. Ukoha and E. Obi, 2002. Effects of rinbacin on rat kidney. Biol. Pharm. Bull., 25: 1022-1025.
    PubMed  |  Direct Link  |  
  63. Afonne, O.J., O.E. Orisakwa, O.A. Ekanem and D.D. Akumka, 2002. Zinc protects chromium-induced testicular injury in mice. Indian J. Pharmacol., 34: 26-31.
    Direct Link  |  
  64. Orisakwe, O.E., R. Asomgha, E. Obi, O.J. Afonne, C.E. Dioka, O. Akumka and N.A. Ilondu, 2001. Ecotoxicological study of the Niger-Delta area of the River Niger. Bull. Environ. Contam. Toxicol., 66: 548-552.
    PubMed  |  
  65. Orisakwe, O.E., P.U. Agbasi, O.J. Afonne, S.I. Ofoefule, E. Obi and C.N. Orish, 2001. Rifampicin pharmacokinetics with and without ciprofloxacin. Am. J. Ther., 8: 151-153.
    PubMed  |  
  66. Orisakwe, O.E., O.J. Afonne, N.A. Ilondu, S.I. Ofoefule and E. Obi, 2001. Adsorptive capacity of activated charcoal for rifampicin with and without sodium chloride and sodium citrate. Biol. Pharm. Bull., 24: 724-726.
  67. Orisakwe, O.E., N.D.A. Ilondu, O.J. Afonne, S.I. Ofoefule C.N. Orish and P.U. Agbasi, 2001. Effect of activated charcoal on diethylcarbamazine absorption in human. Am. J. Ther., 8: 7-9.
    Direct Link  |  
  68. Orisakwe, O.E., A. Oluboyo, S. Ofoefule, E. Obi and N. Ilondu et al., 2001. Adsorption studies of artesunate: Evaluation of saline cathartics as additive in management of artesunate poisoning. J. Health Sci., 47: 491-494.
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  69. Ofoefule, S.I., L.C. Onuoha, M.J. Okonta, P.O. Udeogaranya and O.E. Orisakwe, 2001. Effect of activated charcoal on isoniazid absorption in rabbits. Bolletino Chimico Famaceutico, 140: 183-186.
    Direct Link  |  
  70. Ofoefule, S.I., C.E. Obodo, O.E. Orisakwe, N.A. Ilondu and O.J. Afonne et al., 2001. Some plasma pharmacokinetic parameters of isoniazid (INH) in the presence of a fluoroquinolone antibacterial agent. Am. J. Ther., 8: 243-246.
    PubMed  |  
  71. Chude, M.A., O.E. Orisakwe, O.J. Afonne, K.S. Gamaniel, O.H. Vongtau and E. Obi, 2001. Hypoglycemic effect of the aqueous extract of Boerhavia diffusa leaves. Indian J. Pharm., 33: 215-216.
  72. Agbasi, P.U., O.E. Orisakwe, E. Obi, S.I. Ofoefule, N.A. Ilondu and O.J. Afonne, 2001. Effect of sulphate cathartics on adsorption of rifampicin to activated charcoal. Indian J. Pharmac. Sci., 63: 328-330.
    Direct Link  |  
  73. Orisakwe, O.E., O.J. Afonne, E. Nwobodo, L. Asomugha and C.E. Dioka, 2001. Low-dose mercury induces testicular damage in mice which is protected by zinc. Eur. J. Obst. Gyn. Rep. Biol., 95: 92-96.
    Direct Link  |  
  74. Orisakwe, O.E., N.A. Ilondu, O.J. Afonne, S.I. Ofoefule and C.N. Orish, 2000. Acceleration of body clearance of diethylcarbamazine by oral activated charcoal. Pharm. Res., 42: 167-170.
    PubMed  |  
  75. Orisakwe, O.E., K.C. Chilaka, O.J. Afonne, E. Obi and N. Ilondu, 2000. Evaluation of the developmental toxicity of amlodipine besylate in mice. J. Health Sci., 46: 42-45.
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  76. Orisakwe, O.E., E. Obi and J.K. Emeh, 2000. Antiulceration of Synclisia scabrida. Neutrophil: An alternative ulcer marker?. Asian Pacific J., 15: 77-81.
  77. Orisakwe, O.E., D.D. Akumka, O.J. Afonne and K.S. Gamaniel, 2000. Investigation into the pharmacological basis for folkloric use of Bonny Light Crude Oil in Nigeria. Ind. J. Pharmac., 32: 231-234.
    Direct Link  |  
  78. Orisakwe, O.E., C.N. Orish and L. Egenti, 2000. Childhood non drug poisoning in Nnewi, Nigeria. Trop Doc., 30: 209-211.
    PubMed  |  
  79. Obi, E., J.K. Emeh, O.E. Orisakwe, O.J. Afonne, N.A. Ilondu and P.U. Agbasi, 2000. Invesigation of the biochemical evidence for the antiulcerogenic activity of Syncliscia scabrida. Indian J. Pharm., 32: 381-383.
  80. Ilondu, N., O.E. Orisakwe, S.I. Ofoefule, O.J. Afonne, E. Obi, K.C. Chilaka and C. Orish, 2000. Pharmacokinetics of diethylcarbamazine: Prediction by concentration in saliva. Biol. Pharm.. Bull., 23: 443-445.
    Direct Link  |  
  81. Afonne, O.J., O.E. Orisakwe, G.I. Ndubuka, D.D. Akumka and N. Ilondu, 2000. Zinc protection of mercury-induced hepatic toxicity in mice. Biol. Pharm. Bull., 23: 305-308.
    PubMed  |  
  82. Afonne O.J., O.E. Orisskwe, E. Obi, K.C. Chilaka and D.D. Akumka, 2000. Some pharmacological properties of Synclisia scabrida 111. Indian J. Pharmacol., 32: 239-241.
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  83. Ofoefule S.I., O.E. Orisakwe, O. Onyengba, 2000. Effect of pefloxacin on urinary and salivary concentrations of isoniazid (INH) in six healthy female volunteers. Amer. J. Ther., 7: 313-316.
    Direct Link  |  
  84. Orisakwe, O.E., R. Asomugha, O.J. Afonne, E. Obi, K.C. Chilaka and C.E. Dioka, 1999. Effect of industrial effluents on soil and water qualities in Nnewi, Nigeria. J. Health Sci., 45: 177-183.
    Direct Link  |  
  85. Orisakwe, O.E., E. Obi and A.L. Asomugha, 1999. Use of neutrophil from cardiac puncture and wounds smear as ulcer markers. Nig. J. Med. Res., 3: 4-4.
  86. Orisakwe, O.E., C.E. Dioka and C.S. Ufearo, 1999. The effect of ovarian steroid hormones on the prostaglandins metabolism in the rat lung. Afr. J. Med. Pharm. Sci., 1: 52-55.
  87. Ibezim, E.C., S.I. Ofoefule, C.N.C. Ejeahalaka and O.E. Orisakwe, 1999. In vitro adsorption of ciprofloxacin on activated charcoal and talc. Amer. J. Ther., 6: 199-201.
    PubMed  |  
  88. Ofoefule, S.I., C. Nwankwo, A. Chukwu and O.E. Orisakwe, 1998. In vitro properties of ciprofloxacin suppositories formulated with glycerogelatin and theobroma oil bases. Boll. Chim. Farm., 137: 341-344.
    PubMed  |  
  89. Ofoefule, S.1., O.E. Orisakwe, E.C. 1bezim and C.O. Esimone, 1998. Mechanism of nifedipine release from sustained release tablets formulated with some polymeric materials. Boll. Chim. Farm., 37: 223-227.
  90. Akah, P.A., O.E. Orisakwe, S.V. Nwafor and K.S. Gamaniel, 1998. Prospects of natural plant product as antiulcer agents. J. Pharm. Res. Dev., 3: 57-62.
  91. Akah, P.A., O.E. Orisakwe and K.S. Gamaniel, 1998. Evaluation of Nigerian traditional medicine II: effect of some Nigeria folk remedies on peptic ulcer. J. Ethnopharmac., 62: 123-127.
    PubMed  |  
  92. Orisakwe, O.E., K.C. Chilaka and A.N. Okpogba, 1997. Plasma levels of aluminum after ingestion of achara tea (Cympogopon citratus) in human volunteers. Asian Pacific J. Pharm., 13: 79-82.
  93. Orisakwe, O.E., E. Obi, G. Amilo, C,E, Dioka, O.J. Afonne and C.S. Ufearo, 1997. Sodium and potassium levels and label review studies of Nigeria spices. Indian J. Nutr. Diet., 37: 146-150.
  94. Nwobodo, E., O.E. Orisakwe, C. Okonkwo, C.E. Dioka and G. Amilo, 1997. Dysmenorrhea amongst school girls and treatment. Orient J. Med., 8: 166-169.
  95. Ufearo, C.S., O.E. Orisakwe, J.O. Ogamba and S.O. Maduka, 1996. Evidence for prolactin participation in the control of male fertility. J. Med. Lab. Sci., 5: 148-152.
  96. Orisakwe, O.E., S.I. Ofoefule and E. Nwobodo, 1996. Snuff, harmless substitute for tobacco? Indian. J. Hosp. Pharm. .
  97. Orisakwe, O.E., O.J. Afonne, C.E. Dioka, C.S. Ufearo, A.N. Okpogba and S.I. foefule, 1996. Some pharmacological properties of Synclisia scabrida II. Indian J. Med. Res., 103: 282-284.
    PubMed  |  
  98. Orisakwe, O.E., O.J. Afonne, C.E. Dioka, C.S. Ufearo and S.I. Ofoefule, 1996. Investigation into the oestrogen-like activity of Synclisia scabrida. Fitoterapia, 69: 469-471.
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  99. Orisakwe, O.E., O.J. Afonne and C.E. Dioka, 1996. Preliminary investigation of Synclisia scabrida as a folklore medicine in Nigeria. BMSA, 7: 1-5.
  100. Orisakwe, O.E., C.E. Dioka, E.O. Nwobodo, V.C. Okonkwo, I.C. Anike and A.O. Enendu, 1996. Respiratory abnormalities associated with occupational exposure to particulate insults in Okada (Motorcycle ) operators in Nnewi. Nig. Med. Pract., 32: 36-38.
  101. Orisakwe, O.E., C.E. Dioka, A.N. Okpogba, C.N. Orish and S.I. Ofoefule, 1996. Effect of activated charcoal on rifampicin absorption in man. Tokai J. Exp. Clin. Med., 21: 51-54.
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  102. Orisakwe, O.E., C.E. Dioka and S.I. Ofoefule, 1996. A comparative review of poisoning in Nigeria. J. W. Afr. Pharm., 10: 53-55.
  103. Orisakwe, O.E. and S.I. Ofoefule, 1996. Plasma and saliva concentration of rifampicin in man after oral administration. Tokai J. Exp. Clin. Med., 21: 45-49.
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  104. Orisakwe, O.E. O.J. Afonne and C.E. Dioka, 1996. A papaverine-like activity of Synclisia scabrida in Nigerian folklore. BMSA, 8: 1-5.
  105. Ofoefule, S.I., O.E. Orisakwe and E. Obi, 1996. A procedural update on.laboratory diagnostic test and current treatment protocols for immunologically mediated infertility in the male. Indian. J. Hosp. Pharm. .
  106. Ibezim, E., S.I. Ofoefule and O.E. Orisakwe, 1996. A comparative study of the in vitro adsorption of some drugs on activated charcoal. J. Univ. Sci. Tech. .
  107. Ufearo, C.S. and O.E. Orisakwe, 1995. Restoration of normal sperm characteristics in hypoprolactinemic infertile men treated with metoclopamide and exogenous human prolactin. C1in. Pharm. Ther., 58: 354-359.
  108. Orisakwe, O.E., S.I. Ofoefule, C.E. Dioka, C.S. Ufearo and E.O. Nwobodo, 1995. Carbon Black: A possible role in poison management. Tokai J. Exp. Clin. Med., 20: 67-70.
  109. Orisakwe, O.E., E.O. Nwobodo, C.E. Dioka and A.N. Okogba, 1995. Effect of headaches on working ability. An epidemiological survey of automobile industries. Nig. Med., J., 29: 56-58.
  110. Nwobodo, E., C. Okonkwo, O.E. Orisakwe and E. Obi, 1995. Menarche in Nigeria Ibos. Orient J. Med., 7: 23-25.
  111. Orisakwe, O.E., P.A. Akah and C.N. Orish, 1994. Prevalence of parental administration of drugs to children before coming to the hospital. Trop. Doc., 24: 182-183.
  112. Orisakwe, O.E., E.C. Dioka, C.N. Orish and A.N. Okpogba, 1994. Charcoal and rifampicin pharmacokinetics. Amer. J. Therap., 2: 68-70.
  113. Orisakwe, L.O.E., 1994. Activated charcoal. Is Failure to use it negligence or ignorance? South Med. J., 87: 165-168.
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  114. Orisakwe, O.E. and E. Ogbonna, 1993. Effect of saline cathartics on gastro-intestinal transit time of activated charcoal. Hum. Exp. Toxicol., 12: 403-405.
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  115. Orisakwe, L.O.E. and N. Obi, 1993. In vitro and in vivo absorption studies of diazinon. Hum. Exp. Toxicol., 12: 301-303.
  116. Orisakwe, O.E., 1992. Negligence of activated charcoal due to lack of current information. Israel Med. J., 28: 751-752.
  117. Orisakwe, L.O.E., 1992. Safety warning and first aid instructions on consumer Hum. Exp. Toxicol., 11: 546-548.
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  118. Orisakwe, L.O.E. and A. Akintonwa, 1991. Effect of Na2S04 on adsorption of chloroquine and mefloquine to activated charcoal. East African Med. J., 68: 420-424.
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  119. Orisakwe, L.O.E. and A. Akintonwa, 1991. Comparative adsorption of chloroquine, mefloquine, isoniazid to activated charcoal and locally produced carbon black. (220). West Africa J. Pharmac. Drug Res., 4: 35-37.
  120. Orisakwe, L.O.E. and A. Akintonwa, 1991. In vitro adsorption studies of isoniazid. Hum. Exp. Toxicol., 10: 133-135.
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  121. Orisakwe, L.O.E. and A. Akintonwa, 1990. The adsorption of quinine and quinidine to activated charcoal with and without MgSO4. Vet. Hum. Toxicol., 32: 567-568.
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  122. Akintonwa, A. and L.O.E. Orisakwe, 1990. Effect of saline cathartics on the absorption on sulphamethoxazole to activated charcoal. Arch. Int. Pharmacol. Ther., 304: 290-295.
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  123. Akintonwa, A. and L.O.E. Orisakwe, 1990. Effect of activated charcoal on chloroquine absorption in man. Nig. J. Physiol. Sci., 6: 18-27.
  124. Akintonwa.A. and O.E. Orisakwe, 1988. Adsorption of metronidazole and tinidazole to activated charcoal and effect of magnesium sulphate. Vet. Hum. Toxicol., 30: 556-558.
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