Dr. Eleazu   Chinedum Ogbonnaya
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Dr. Eleazu Chinedum Ogbonnaya

Lecturer I
Federal University, Nigeria


Highest Degree
Ph.D. in Nutritional Biochemistry from Michael Okpara University of Agriculture, Nigeria

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Biography

Dr. Eleazu Chinedum Ogbonnaya is currently working as Head of Department of Biochemistry. National Root Crops Research Institute, Umudike, Umuahia, Abia State, Nigeria. He has completed his Ph.D. in Nutritional Biochemistry from Michael Okpara University of Agriculture, Nigeria. He also performed his duties as Chemistry Teacher at Oboro Senior Secondary School, Ikwuano, Umuahia, and Michael Okpara University of Agriculture, Chemistry Lecturer to pre-degree students at Government Secondary School, Akwanga, Nasarawa State. He is member of editorial board in International Journal of Basic and Applied Sciences, and International Journal of Herbs and Medicinal Plants. He is member of Nigerian Society of Biochemistry and Molecular Biology. He has published 30 research articles in journals, 4 conference proceedings and 4 book abstracts contributed as author/co-author.

Area of Interest:

Biomedical Sciences
100%
Clinical Biochemistry
62%
Metabolic Disorder
90%
Medicinal Herbs
75%
Molecualar Biology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Eleazu, C., C. Egedigwe-Ekeleme, A. Famurewa, M. Mohamed and G. Akunna et al., 2019. Modulation of the lipid profile, hepatic and renal antioxidant activities, and markers of hepatic and renal dysfunctions in alloxan-induced diabetic rats by virgin coconut oil. Endocrine Metab. Immune Disord. Drug Targets, 10.2174/1871530319666190119101058.
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  2. Egedigwe-Ekeleme, C.A., I.I. Ijeh, P.N. Okafor, C.O. Eleazu and C. Egedigwe, 2019. Effect of fractions of Vernonia amygdalina on some biochemical parameters in high fat diet induced obese rats. Endocr. Metab. Immune Disord. Drug Targets, 10.2174/1871530319666190222163159 .
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  3. David, E., C. Eleazu, N. Igweibor, C. Ugwu, G. Enwefa and N.N. Nwigboji, 2019. Comparative study on the nutrients, heavy metals and pesticide composition of some locally produced and marketed rice varieties in Nigeria. Food Chem., 278: 617-624.
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  4. Ngozi, A., O. Christopher, I. Ifeoma, E. Chinedum, I. Kalu and O. Chima, 2018. Ameliorative potentials of methanol fractions of Cnidoscolus aconitifolius on some hematological and biochemical parameters in streptozotocin diabetic rats. Endocr Metab. Immune. Disord. Drug Targets, 18: 637-645.
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  5. Igwe, A. and C. Eleazu, 2018. Effect of processing on the biochemical contents of Acanthus montanus (Nees) T. Anderson (Acanthaceae) leaves. Food Sci. Nutr., 6: 388-394.
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  6. Eleazu, K., P. Maduabuchi and C. Eleazu, 2018. Effect of ethanol extract of boiled breadfruit (Treculia Africana) seed on the oral glucose tolerance, lipid profile and body weight of normoglycemic albino rats. Food Sci. Nutr., 6: 904-911.
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  7. Eleazu, C., C. Ayogu, K. Eleazu and N. Achi, 2018. Free fatty acid receptor 1 as a novel therapeutic target for type 2 diabetes mellitus-current status. Chem. Biol. Int., 289: 32-39.
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  8. Eleazu, C., A. Sampson, S. Saidu, K. Eleazu and C. Egedigwe-Ekeleme, 2018. Starch digestibility, polyphenol contents and in vitro alpha amylase inhibitory properties of two varieties of cocoyam (Colocassia esculenta and Xanthosoma mafafa) as affected by cooking. J. Food Meas. Charact., 12: 1047-1053.
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  9. Chinedum, E., S. Sanni, N. Theressa and A. Ebere, 2018. Effect of domestic cooking on the starch digestibility, predicted glycemic indices, polyphenol contents and alpha amylase inhibitory properties of beans (Phaseolis vulgaris) and breadfruit (Treculia africana). Int. J. Biol. Macromol., 106: 200-206.
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  10. Udeme, N., P. Okafor and C. Eleazu, 2017. Evaluation of the distribution of cyanide in the peels, pulps and leaves of three new yellow cassava (Manihot esculenta Crantz) varieties for potential livestock feeds. Prog. Nutr., 19: 137-141.
  11. Saidu, S., C.O. Eleazu, D. Ebuka, A. Ikechukwu, M. Blessing, N. Chibuike and C. Chukwuma, 2017. Starch hydrolysis, polyphenol contents and in vitro alpha amylase inhibitory properties of some nigerian foods as affected by cooking. Front. Nutr., Vol. 4. 10.3389/fnut.2017.00060.
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  12. Eleazu, C.O., K.C. Eleazu, M.A. Iroaganachi and W. Kalu, 2017. Starch digestibility and predicted glycemic indices of raw and processed forms of Hausa potato (Solenostemon rotundifolius Poir). J. Food Biochem., Vol. 41. 10.1111/jfbc.12355.
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  13. Eleazu, C., N. Obianuju, K. Eleazu and W. Kalu, 2017. The role of dietary polyphenols in the management of erectile dysfunction-mechanisms of action. Biomed. Pharmacother., 88: 644-652.
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  14. Eleazu, C., K. Eleazu and W. Kalu, 2017. Management of benign prostatic hyperplasia: Could dietary polyphenols be an alternative to existing therapies? Front. Pharmacol., Vol. 8. 10.3389/fphar.2017.00234.
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  15. Eleazu, C., I. Ezekwibe, M. Egbe, S. Saidu, K. Eleazu and C. Egedigwe, 2017. Dietary intake of boiled breadfruit (Treculia africana) seeds did not improve hyperglycemia in streptozotocin induced diabetic rats: Effect on the oral glucose tolerance of normoglycemic rats. Acta Sci. Pol. Technol. Aliment., 16: 93-99.
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  16. Achi, N.K., O.C. Ohaeri, I.I. Ijeh and C. Eleazu, 2017. Modulation of the lipid profile and insulin levels of streptozotocin induced diabetic rats by ethanol extract of Cnidoscolus aconitifolius leaves and some fractions: Effect on the oral glucose tolerance of normoglycemic rats. Biomed. Pharmacother., 86: 562-569.
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  17. Winner, K., O. Polycarp, I. Ifeoma and E. Chinedum, 2016. Effect of fractions of kolaviron on some indices of benign prostatic hyperplasia in rats: Identification of the constituents of the bioactive fraction using GC-MS. RSC Adv., 6: 94352-94360.
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  18. Kalu, W.O., P.N. Okafor, I.I. Ijeh and C. Eleazu, 2016. Effect of kolaviron, a biflavanoid complex from Garcinia kola on some biochemical parameters in experimentally induced benign prostatic hyperplasic rats. Biomed. Pharmacother., 83: 1436-1443.
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  19. Eleazu, C.O., K.C. Eleazu and M.A. Iroaganachi, 2016. Effect of cocoyam (Colocasia esculenta), unripe plantain (Musa paradisiaca) or their combination on glycated hemoglobin, lipogenic enzymes and lipid metabolism of streptozotocin-induced diabetic rats. Pharm. Biol., 54: 91-97.
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  20. Eleazu, C.O., K.C. Eleazu and M. Iroaganachi, 2016. In vitro starch digestibility, α-amylase and α-glucosidase inhibitory capacities of raw and processed forms of three varieties of Livingstone potato (Plectranthus esculentus). Innov. Food Sci. Emerg. Technol., 37: 37-43.
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  21. Eleazu, C.O., 2016. The concept of low glycemic index and glycemic load foods as panacea for type 2 diabetes mellitus; prospects, challenges and solutions. Afr. Health Sci., 16: 468-479.
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  22. Eleazu, C.O., 2016. Characterization of the natural products in cocoyam (Colocasia esculenta) using GC-MS. Pharm. Biol., 54: 2880-2885.
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  23. Udeme, N., P. Okafor and C. Eleazu, 2015. The metabolic effects of consumption of yellow cassava (Manihot esculenta Crantz) on some biochemical parameters in experimental rats. Int. J. Toxicol., 34: 559-564.
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  24. Okorie, D.O., C.O. Eleazu and P. Nwosu, 2015. Nutrient and heavy metal composition of plantain (Musa paradisiacal) and Banana (Musa paradisiacal) Peels. J. Nutr. Food Sci., 10.4172/2155-9600.1000370.
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  25. Okorie, D.O., C.O. Eleazu and O.W. Akabuogu, 2015. Quality evaluation of commercially sold table water samples in Michael Okpara University of Agriculture, Umudike, Nigeria and surrounding environments. Toxicol. Rep., 2: 904-907.
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  26. Iroaganachi, M., C.O. Eleazu, P.N. Okafor and N. Nwaohu, 2015. Effect of unripe plantain (Musa paradisiacal) and ginger (Zingiber officinale) on blood glucose, body weight and feed intake of Streptozotocin-induced diabetic rats. Open Biochem. J., 9: 1-6.
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  27. Iroaganachi, M., C.O. Eleazu and P.N. Okafor, 2015. Effect of unripe plantain (Musa paradisiacae) and ginger (Zingiber officinale) on renal dysfunction in streptozotocin-induced diabetic rats. J. Pancreas, (In Press). .
  28. Iroaganachi, M., C.O. Eleazu and P.N. Okafor, 2015. Effect of unripe plantain (Musa paradisiaca) and ginger (Zingiber officinale) on renal dysfunction in streptozotocin-induced diabetic rats. J. Pancreas, 16: 167-170.
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  29. Eleazu, C.O. and P.N. Okafor, 2015. Use of unripe plantain (Musa paradisiaca) in the management of diabetes and hepatic dysfunction in streptozotocin induced diabetes in rats. Interventional Med. Appl. Sci., 7: 9-16.
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  30. Eleazu, C., K. Eleazu, C. Chukwuma, A. Ironkwe and A. Igwe, 2015. Polyphenolic composition and antioxidant activities of 6 new turmeric (Curcuma Longa L.) Accessions. Rec. Patents Food Nutr. Agric., 7: 22-27.
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  31. Eleazu C.O. and K.C. Eleazu, 2015. Nutrient composition, antioxidant capacity and natural products in Livingstone potato (Plectranthus esculentus). J. Food Process. Preserv., 39: 3050-3058.
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  32. Awa, E. and C. Eleazu, 2015. Bioactive constituents and antioxidant activities of raw and processed cocoyam (Colocasia esculenta). Nutra Food, 14: 133-140.
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  33. Ogbonnaya, E.C., 2014. Effect of livingstone potato (Plectranthus esculentus NE Br) on hepatic Glucose-6-phosphophate dehydrogenase activity of streptozotocin induced diabetic rats. J. Pancreas, 15: 360-364.
  34. Eleazu, O.C., K.C. Eleazu and S. Kolawole, 2014. Use of indigenous technology for the production of high quality cassava flour with similar food qualities as wheat flour. Acta Scientarium Polonorum Technol. Aliment, 13: 249-256.
  35. Eleazu, C.O., P.N. Okafor and I. Ifeoma, 2014. Biochemical basis of the use of cocoyam (Colocassia esculenta L.) in the dietary management of diabetes and its complications in streptozotocin induced diabetes in rats. Asian Pacific J. Trop. Dis., 4: S705-S711.
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  36. Eleazu, C.O., K.C. Eleazu, S.C. Chukwuma, J. Okoronkwo and C.U. Emelike, 2014. Effect of livingstone potato (Plectranthus esculenthus N.E.Br) on hyperglycemia, antioxidant activity and lipid metabolism of streptozotocin induced diabetic rat. Toxicol. Rep., 1: 674-681.
  37. Eleazu, C.O., K.C. Eleazu, A. Ironkwe and M.A. Iroaganachi, 2014. Effect of livingstone potato (Plectranthus esculenthus N.E.Br) on diabetes and its complications in streptozotocin induced diabetes in rats. Diabetes Metab. J., 38: 366-374.
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  38. Eleazu, C., K. Eleazu, C. Aniedu, J. Amajor, A. Ikpeama and I. Ebenzer, 2014. Effect of partial replacement of wheat flour with high quality cassava flour on the chemical composition, antioxidant activity, sensory quality and microbial quality of bread. Prev. Nutr. Food Sci., 19: 115-123.
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  39. Onunogbo, O.C., O.C. Ohaeri and C.O. Eleazu, 2013. Effect of mistletoe extract (Loranthus micranthus) on the blood glucose, liver enzymes and electrolyte balance in alloxan induced diabetic rats. Am. J. Biochem. Mol. Biol., 3: 143-150.
  40. Okechukwu, A.C., O.O. Adeyemi, E. Chinedu, O.C. Peggy and N.C. Chukwuma, 2013. Multi-location evaluation of turmeric genotypes in Nigeria. J. Agric. Sci. Technol., 3: 842-846.
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  41. Ogbonnaya, E.C. and E.K. Chinedum, 2013. Health promoting compounds and in vitro antioxidant activity of raw and decoctions of Gnetum aficanum welw. Asian Pacific J. Trop. Dis., 3: 472-479.
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  42. Ogbonnaya, E.C. and E.K. Chinedum, 2013. Bioactive constituents and in vitro antioxidant capacity of water leaf (Talinum triangulare) as affected by domestic cooking. Eur. J. Med. Plants, 3: 540-551.
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  43. Iwo, G.A., C.O. Amadi, C.O. Eleazu and J.U. Ukpabi, 2013. Induced mutagenesis on ginger for improved yield components and oleoresin content. Can. J. Plant Breed., 1: 90-96.
  44. Eleazu, C.O., S. Kolawole and E. Awa, 2013. Phytochemical composition and antifungal actions of aqueous and ethanolic extracts of the peels of two yam varieties. Med. Aromat. Plants, Vol. 2. .
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  45. Eleazu, C.O., M.A. Iroaganachi and J.O. Okoronkwo, 2013. Determination of the physico-chemical composition, microbial quality and free radical scavenging activities of some commercially sold honey samples in Aba, Nigeria: The effect of varying colours. Int. J. Biomed. Res., 4: 32-41.
  46. Eleazu, C.O., M. Iroaganachi, P.N. Okafor, I.I. Ijeh and K.C. Eleazu, 2013. Ameliorative potentials of ginger (Z. Officinale Roscoe) on relative organ weights in streptozotocin induced diabetic rats. Int. J. Biomed. Sci., 9: 82-90.
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  47. Eleazu, C.O., M. Iroaganachi and K.C. Eleazu, 2013. Ameliorative potentials of cocoyam (Colocasia esculenta L.) and unripe plantain (Musa paradisiaca L.) on the relative tissue weights of streptozotocin-induced diabetic rats. J. Diabetes Res., 10.1155/2013/160964.
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  48. Eleazu, C.O., K.C. Eleazu, S. Chukwum and U.N. Essien, 2013. Review of the mechanism of cell death resulting from streptozotocin challenge in experimental animals, its practical use and potential risk to humans. J. Diabetes Metab. Disorders, Vol. 12. 10.1186/2251-6581-12-60.
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  49. Eleazu, C.O., C.O. Amadi, G. Iwo, P. Nwosu and C.F. Ironua, 2013. Chemical composition and free radical scavenging activities of 10 elite Acces-sions of ginger (Zingiber officinale Roscoe). J. Clinic. Toxicol., Vol. 3. .
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  50. Eleazu, C.O. and K.C. Eleazu, 2013. Ameliorating potentials of 3 medicinal plants on relative pancreatic weights in streptozotocin induced diabetic rats. J. Diabetes Metab., Vol. 4. .
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  51. Eleazu, C.O. and C. Ironua, 2013. Physicochemical composition and antioxidant properties of a sweetpotato variety (Ipomoea batatas L.) commercially sold in South Eastern Nigeria. Afr. J. Biotechnol., 12: 720-727.
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  52. Onunogbo, C., O.C. Ohaeri, C.O. Eleazu and K.C. Eleazu, 2012. Chemical Composition of Mistletoe Extract (Loranthus micranthus) and Its Effect on the Protein, Lipid Metabolism and the Antioxidant Status of Alloxan Induced Diabetic Rats. E3 J. Med. Res., 1: 57-62.
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  53. Eleazu, C.O., K.C. Eleazu, J.U. Amajor and E.E. Amajor, 2012. Serro-prevalence of Rubella virus antibodies in pregnant women attending Plateau Specialist Hospital, Jos. J. Biotechnol. Pharm. Res., 3: 10-14.
  54. Eleazu, C.O., K.C. Eleazu, E. Awa and S.C. Chukwuma, 2012. Comparative Study of the Phytochemical Composition of the Leaves of Five Nigerian Medicinal Plants. E3 J. Biotechnol. Pharm. Res., 3: 42-46.
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  55. Eleazu, C.O., J.U. Amajor, A.I. Ikpeama, V. Obi and O. Kolawole, 2012. Extractable sugars and microbial quality of 5 honey samples from umudike farms and different locations in South Eastern Nigeria. Int. J. Biol. Pharm. Allied Sci., 1: 1270-1280.
  56. Eleazu, C.O., E. Oti, K.C. Eleazu and V. Obi, 2012. Nutrient composition, polyphenolic content and free radical scavenging activities of five honey samples from NRCRI, Umudike and different locations in South Eastern Nigeria. Afr. J. Food Sci. Technol., 3: 160-167.
  57. Eleazu, C.O., C.O. Amadi and G. Iwo, 2012. Biochemical qualities of 10 elite accessions of ginger (Zingiber officinale Roscoe). Afr. J. Food Sci. Technol., 3: 187-192.
  58. Eleazu, C.O., A.I. Ikpeama, J.U. Amajor and K.C. Eleazu, 2012. Proximate composition, essential oils and energy value of 10 new varieties of ginger (Zingiber officinale roscoe). Int. J. Biol. Pharm. Allied Sci., 1: 1293-1303.
  59. Eleazu, C.O. and K.C. Eleazu, 2012. Physico-chemical properties and antioxidant potentials of 6 new varieties of ginger (Zingiber officinale). Am. J. Food Technol., 7: 214-221.
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  60. Eleazu, C.O. and K.C. Eleazu, 2012. Determination of the proximate composition, total carotenoid, reducing sugars and residual cyanide levels of flours of 6 new yellow and white cassava (Manihot esculenta Crantz) varieties. Am. J. Food Technol., 7: 642-649.
    Direct Link  |  
  61. Amajor, J.U., C.O. Eleazu, E.E. Amajor, C.F. Ironua and P. Nwosu, 2012. Comparative evaluation of the physicochemical composition and microbial quality of seven different water sources used in processing root and tuber crops in Umudike, Nigeria. Afr. J. Biotechnol., 11: 15330-15335.
  62. Eleazu, C.O., P.N. Okafor, J. Amajor, E. Awa, A. Ikpeama and K.C. Eleazu, 2011. Chemical composition, antioxidant activity, functional properties and inhibitory action of unripe plantain (M. Paradisiacae) flour. Afr. J. Biotechnol., 10: 16948-16952.
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  63. Eleazu, C.O., J.U. Amajor, A.I. Ikpeama and E. Awa, 2011. Studies on the nutrient composition, antioxidant activities, functional properties and microbial load of the flours of 10 elite cassava (Manihot esculenta) varieties. Asian J. Clin. Nutr., 3: 33-39.
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  64. Eleazu, C.O., J.U. Amajor and A. Ikpeama, 2011. Total antioxidant capacity, nutrient composition, microbial loads and percentage inhibitory activity of unripe plantain flour. Can. J. Pure Appl. Sci., 5: 1501-1504.
  65. Eleazu, C.O., E. Oti, J.U. Amajor, A.I. Ikpeama, E. Awa and K.C. Eleazu, 2011. Nutritional evaluation and microbial load of cassava (Manihot esculenta) sieviates and peels fermented in brine. Int. J. Adv. Sci. Tech. Res., 1: 1-23.
  66. Amajor, J.U., C.O. Eleazu, E. Oti, E.F. Udoh and A.I. Ikpeama et al., 2011. Effect of variety on the physico-chemical, carotenoid and microbial loads of flours of five new varieties of sweet potato. Biotechnology, 10: 286-291.
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