Dr. Friday Effiong Uboh

Dr. Friday Effiong Uboh

Professor
University of Calabar, Nigeria


Highest Degree
Ph.D. in Biochemistry from University of Calabar, Calabar, Nigeria

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Area of Interest:

Plant and Soil Sciences
100%
Biochemistry
62%
Medicinal Plant Research
90%
Endocrinology
75%
Toxicology
55%

Selected Publications

  1. Udosen, G.E., F.E. Uboh, D. Amaechi, M.O. Odey and J.E. Mgbang, 2019. Risk assessment of heavy metal contaminants in some common ready to eat meals sold at petrol stations in calabar metropolis. Asian J. Res. Nurs. Health, 2: 1-6.
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  2. Ufot, S.U., U.O. Luke, F.E. Uboh and E.U. Eyong, 2018. Protective effects of vitamins E and C against crude oil induced reproductive toxicity in rats. Curr. Trends Clin. Toxicol., Vol. 1, No. 1. 10.29011/CTT-101.100001.
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  3. Ufot, S.U., U.O. Luke, F.E. Uboh and E.U. Eyong, 2018. Protective effect of ascorbic acid against Bonny Light Crude oil induced atherosclerosis in rats. Res. J. Environ. Toxicol., 12: 11-17.
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  4. Iwara, I.A., G.O. Igile, F.E. Uboh, M.U. Eteng and P.E. Ebong, 2018. Analysis of bioactive constituents of n-hexane and methanol fractions of Vernonia calvoana Extracts using Gas Chromatography-Mass Spectrometry. Pharmacogn. J., 10: 857-858.
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  5. Emmanuel, M.U., M.A. Agiang, E.U. Friday, O.O. Blessing, O. Favour and O. Rowland, 2018. Uppercott: Implication in nephrotoxicity in male albino wistar rats. Int. J. Biol. Res., 3: 05-10.
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  6. Modo, E.U., F.E. Uboh, M.A. Agiang and E.G. Ewere, 2017. Exposure to uppercott induces hepatotoxicity in male albino wistar rats. Int. J. Scient. World, 5: 74-79.
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  7. Iwara, I.A., G.O. Igile, F.E. Uboh, K.N. Elot and M.U. Eteng, 2017. Biochemical and antioxidants activity of crude, methanol and n-hexane fractions of Vernonia calvoana on streptozotocin induced diabetic rats. J. Pharm. Phytother., 9: 24-34.
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  8. Uboh, F.E., S.U. Ufot, U.O. Luke, G.O. Igile and C.M. Ozojie, 2016. Protective effect of vitamins C and E against Nitrocellulose thinner induced nephrotoxicity in albino Wistar rats. J. Clin. Toxicol., Vol. 6 10.4172/2161-0495.1000280.
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  9. Uboh, F.E., S. Ufot and E. Mboso, 2016. Comparative haematopoietic effect of ascorbic acid and aqueous extract of Psidium guajava leaves in male rats. J. Ethnobiol. Traditional Med. Photon., 127: 1261-1266.
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  10. Ekaidem, I.S., I.F. Usoh and F.E. Uboh., 2016. Phenytoin induced changes in glucose and lipid metabolism is related to increased Urate synthesis. Br. J. Med. Med. Res., 16: 1-10.
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  11. Usoh, I.F., H.D. Akpan, I.S. Ekaidem, F.E. Uboh and U.O. Luke, 2015. Changes in blood glucose, body weights and serum lipids of streptozotocin-induced diabetic rats treated with combined leaf extracts of Gongronema latifolium and Ocimum gratissimum. European J. Scient. Res., 130: 68-81.

  12. Iwara, I.A., G.O. Igile, F.E. Uboh, E.U. Eyong and P.E. Ebong, 2015. Hypoglycemic and hypolipidemic potentials of extract of Vernonia calvoana on alloxan-induced diabetic albino wistar rats. Eur. J. Med. Plants, 8: 78-86.
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  13. Edet, A., D. Amaechi, E.O. Udosen and F.E. Uboh, 2015. Evaluation of the effect of ethanolic leaf extract of Solenostemon monostachyus on blood glucose and liver enzymes in stz induced diabetic rats. Eur. Scient. J., 11: 161-170.
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  14. Uboh, F.E., S. Ufot, E. Mboso and E.U. Eyong, 2014. Effect of Costus afer Leaves’ Juice on Nitrocellulose Thinner Induced Nephrotoxicity in Rats. Res. J. Environ. Toxicol., 8: 37-45.
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  15. Uboh, F.E., I.O. Williams and N.C. Essien, 2014. Effect of processing on the proximate and mineral composition of Archachatina marginata and Achatina achatina. Food Public Health, 4: 10-14.
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  16. Uboh F.E., E. Mboso, S. Ufot, G.O. Igile and P.E. Ebong, 2014. Hepatotoxicity effect of oral exposure to nitrocellulose thinner in albino Wistar rats. J. Toxicol. Health. Photon., 104: 448-455.
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  17. Okonkwo, P.O. and Z.S.C. Okoye, 2014. Comparative effects of antidiabetic drug, metformin and deferoxamine, on the hepatotoxic and nephrotoxic side effects of streptozotocin-induced diabetes mellitus in rats. Br. J. Pharm. Res., 4: 1820-1832.
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  18. Mboso, O.E., M.O. Odey, F.E. Uboh, N.M. Essien, O. Chidinma and E.U. Eyong, 2014. Erythropoietic Effects of Eremomastax polysperma Leaf Extracts on Female Prepubertal and Pubertal Wistar Rats. Br. J. Pharm. Res., 4: 1833-1839.
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  19. Igile, G., G. Essiet, F. Uboh and E. Edet, 2014. Rapid method for the identification and quantification of allantoin in body creams and lotions for regulatory activities. Int. J. Curr. Microbiol. App. Sci., 3: 552-557.
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  20. Ekaidem, I.S., I.F. Usoh, M.I. Akpanabiatu, F.E. Uboh and H.D. Akpan, 2014. Urate synthesis and oxidative stress in phenytoin hepatotoxicity: The role of antioxidant vitamins. Pak. J. Biol. Sci., 17: 1179-1184.
    CrossRef  |  

  21. Uboh, F.E., S.U. Ufot and E.U. Eyong, 2013. Comparative effect of withdrawal from exposure on gasoline and diesel induced nephrotoxicity in male albino wistar rats. J. Clin. Toxicol., Vol. 3. 10.4172/2161-0495.1000170.
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  22. Uboh, F.E., I.E. Okon and E.E. Edet, 2013. Location of planting dependent contamination of fluted pumpkin (Telfeiria ocidentalis) leaves with heavy metals. J. Food. Nut. Sci., 1: 18-22.
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  23. Uboh, F.E., G.O. Igile, I.E. Okon and P.E. Ebong, 2013. Comparative hypolipidaemic effect of aqueous extract of Psidium guajava leaves and ascorbic acid in male rats. Int. J. Biochem. Res. Rev., 3: 129-136.

  24. Uboh, F.E. and S. Ufot, 2013. Withdrawal from exposure reverses hematotoxicity and hepatotoxicity caused by oral exposure to nitrocellulose thinner in male rats. J. Clin. Toxicol., Vol. 3. 10.4172/2161-0495.1000173.
    CrossRef  |  Direct Link  |  

  25. Ndem, J.I., O. Otitoju, M.I. Akpanaiabiatu, F.E. Uboh, A.F. Uwah and O.A. Edet, 2013. Haematoprotective property of Eremomastax speciosa (Hochst.) on experimentally induced anaemic Wistar rats. Ann. Biol. Res., 4: 356-360.
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  26. Igile, G.O., I.A. Iwara, B.I.A. Mgbeje, F.E. Uboh and P.E. Ebong, 2013. Phytochemical, proximate and nutrient composition of Vernonia calvaona Hook (Asterecea): A green-leafy vegetable in Nigeria. J. Food Res., 2: 1-11.
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  27. Eve, M.O., F.E. Uboh, I.A. Iwara, E.E. Ubana and P.E. Ebong, 2013. Eremomastax speciosa, Eremomastax polysperma and Cassia alata leaf extracts enhances fertility through modulation of serum levels of some reproductive hormones in female Wistar rats. J. Obstetrics, Gynecol. Reprod. Biol. Photon., 114: 182-188.

  28. Edet, E.E., E. David-Oku, M.I. Akpanabiatu, G.O. Igile, B. Mgbeje, G.E. Egbung and F.E. Uboh, 2013. Clinical significance of the Gongronema latifolium leaf extracts on some serum enzymes in diabetic rats. J. Pharm. Biomed. Sci., 29: 781-787.
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  29. Edet E.E., T.E. Edet, M.I. Akpanabiatu, E. David-Oku and I.J. Atangwho et al., 2013. Toxico-pathological changes and phytochemically-induced alleviation in diabetic rats treated with Gongronema latifolium leaf extracts. J. Med. Med. Sci., 4: 204-213.

  30. Abubakar, M.B., W.Z. Abdullah, S.A. Sulaiman, F.E. Uboh and B.S. Ang, 2013. Effect of honey supplementation on toxicity of gasoline vapor exposure in rats. Int. J. Applied Res. Natural Prod., 6: 16-22.
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  31. Uboh, F.E., P.E. Ebong, H.D. Akpan, I.F. Usoh, 2012. Hepatoprotective effect of vitamins C and E against gasoline vapour-induced liver injury in male rats. Turk. J. Biol., 36: 217-223.
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  32. Uboh, F.E., M.I. Akpanabiatu, A.N. Aquaisua and E.I. Bassey, 2012. Oral exposure to nitrocellulose thinner solvent induces nephrotoxicity in male albino wistar rats. J. Pharmacol. Toxicol., 7: 78-86.
    CrossRef  |  

  33. Uboh, F.E., I.F. Usoh, P. Nwankpa and G.O. Obochi, 2012. Effect of oral exposure to nitrocellulose thinner on haematological profiles of male albino wistar rats. Am. J. Biochem. Mol. Biol., 2: 227-234.
    CrossRef  |  Direct Link  |  

  34. Uboh, F.E., E.E. Edet, I.J. Atangwo and E. David-Oku, 2012. Effect of Gongronema latifolium leaf extract on some kidney enzymes and protein levels in diabetic and non-diabetic rats. J. Pharm. Biomed. Sci., Vol. 21. .
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  35. Uboh, F.E., M.I. Akpanabiatu, P.E. Ebong and E.U. Essien, 2011. Effect of vitamins A and E on gasoline vapours induced atherosclerosis in male rats. Int. J. Curr. Biomed. Pharm. Res., 1: 88-92.

  36. Uboh, F.E., M.I. Akpanabiatu, E.E. Edet and I.E. Okon, 2011. Distribution of heavy metals in fluted pumpkin (Telfairia ocidentalis) leaves planted at different distances away from the traffic congested highways. Int. J. Adv. Biotechnol. Res., 2: 250-256.

  37. Uboh, F.E., E.N. Asuquo, M.U. Eteng and E.O. Akpanyung, 2011. Endosulfan-induces renal toxicity independent of the route of exposure in rats. Am. J. Biochem. Mol. Biol., 1: 359-367.
    CrossRef  |  

  38. Uboh, F.E., E.N. Asuquo and M.U. Eteng, 2011. Endosulfan-induced hepatotoxicity is route of exposure independent in rats. Toxicol. Ind. Health, 27: 483-488.
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  39. Uboh, F., M. Akpanabiatu, E. Edet and P. Ebong, 2011. Vitamins A, C and E ameliorate gasoline vapour-induced toxicity effect on sex hormonal levels in female wistar rats. Acta Endocrinol., 7: 189-198.
    CrossRef  |  

  40. Uboh, F., 2011. Conceptual Enzymology and Biological Oxidation. LAP LAMBERT Academic Publishing GmbH & Co. KG, Deutschland, Germany, ISBN: 978-3-7869-5.

  41. Uboh, F., 2011. Comparative and Plant Biochemistry with Metabolic Connotations. LAP LAMBERT Academic Publishing GmbH & Co. KG, Deutschland, Germany, ISBN: 978-3-8433-7342-5.

  42. Essien N.C. and F.E. Uboh, 2011. Proximate, toxicants and vitamins composition of ''Tom Brown'', a locally prepared weaning Formula.. Int. J. Curr. Scient. Res., 1: 79-82.

  43. Edet, E.E., M.I. Akpanabiatu, F.E. Uboh, T.E. Edet, A.E. Eno, E.H. Itam and I.B. Umoh, 2011. Gongronema latifolium crude leaf extract reverses alterations in haematological indices and weight-loss in diabetic rats. J. Pharmacol. Toxicol., 6: 174-181.
    CrossRef  |  Direct Link  |  

  44. Edet, E.E., I.J. Atangwho, M.I. Akpanabiatu, T.E. Edet, F.E. Uboh and E. David-Oku, 2011. Effect of Gongronema latifolium leaf extract on some liver enzymes and protein levels in diabetic and non-diabetic rats. J. Pharm. Biomed. Sci., 1: 104-107.
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  45. Uboh, F.E., M.U. Eteng, P.E. Ebong and I.B. Umoh, 2010. Vitamins A and E reverse gasoline vapors-induced hematotoxicity and weight loss in female rats. Toxicol. Ind. Health, 26: 559-566.
    CrossRef  |  

  46. Uboh, F.E., M.I. Akpanabiatu, I.S. Ekaidem, M.U. Eteng and E.U. Eyong, 2010. Exposure to gasoline and kerosene vapours: A risk factor for nephrotoxicity in rats. Internet J. Toxicol., Vol. 7. .
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  47. Uboh, F.E., M.I. Akpanabiatu, E.E. Edet and P.E. Ebong, 2010. Increase activity of serum total and prostatic acid phosphatase, alkaline phosphatase, gamma glutamyltransferase and testosterone level in rats exposed to gasoline vapours. J. Med. Med. Sci., 1: 16-20.

  48. Uboh, F.E., I.E. Okon and M.B. Ekong, 2010. Effect of aqueous extract of Psidium guajava leaves on liver enzymes, histological integrity and hematological indices in rats. Gastroenterol. Res., 3: 32-38.
    CrossRef  |  

  49. Uboh, F.E., Ebong, P.E. and E. Mbi, 2010. Cultural discrimination in the Consumption of black snail (Archachatina marginata) and white snail (Achatina achatina); any scientific justification?. Int. Res. J. Microbiol., 1: 13-17.

  50. Uboh, F.E., E.E. Edet, M.U. Eteng and E.U. Eyong, 2010. Comparative effect of aqueous extract of P. guajava leaves and ascorbic acid on serum sex hormones levels in male and female rats. J. Applied Sci. Res., 6: 275-279.
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  51. Uboh, F., P. Ebong and E. Udosen, 2010. [Effect of vitamin C on gasoline vapor-induced reproductive toxicity in female rats]. Turk. J. Endocrinol. Metab., 14: 26-30.
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  52. Uboh, F., E. Udosen and P. Ebong, 2010. Protective effect of vitamin C against gasoline vapours-induced reproductive toxicity in male wistar albino rats. General Endocrinol., 3: 305-314.
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  53. Okwari, O.O., E.E. Edet and F.E. Uboh, 2010. The effect of Treculia africana African breadfruit on serum electrolyte enzyme and some haematological parameter in rat: a sub-chronic study. Global J. Pure Appl. Sci., 16: 251-255.
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  54. Essien, N.C., I.B. Umoh, F.E. Uboh and O.O. Lawal, 2010. Evaluation of the nutritional quality of “Tom Brown” weaning diet. Global J. Pure Appl. Sci., 16: 155-159.
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  55. Atangwho, I.J., P.E. Ebong, G.E. Egbung, F.E. Uboh and A.B. Utu-Baku, 2010. Extracts of Azadirachta Indica can modulate the possible hepatotoxic effect of Vernonia amygdalina in diabetic and non-diabetic rats. J. Applied Sci. Res., 6: 2275-2279.

  56. Uboh, F.E., P.E. Ebong and I.B. Umoh, 2009. Comparative hepatoprotective effect of vitamins A and E against gasoline vapor toxicity in male and female rats. Gastroenterol. Res., 2: 295-302.
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  57. Uboh, F.E., M.I. Akpanabiatu, Y. Alozie, E.E. Edet, J.I. Ndem and P.E. Ebong, 2009. Comparative effect of vitamins A and E on gasoline vapours-induced haematotoxicity and weight-loss in male rats. Int. J. Pharmacol., 5: 215-221.
    CrossRef  |  Direct Link  |  

  58. Uboh, F.E., M.I. Akpanabiatu, J.I. Ndem, Y. Alozie and P.E. Ebong, 2009. Comparative nephrotoxic effect associated with exposure to diesel and gasoline vapours in rats. J. Toxicol. Environ. Health Sci., 1: 68-74.
    Direct Link  |  

  59. Uboh, F.E., I.S. Ekaidem, P.E. Ebong and I.B. Umoh, 2009. The hepatoprotective effect of vitamin A against gasoline vapor toxicity in rats. Gastroenterol. Res., 2: 162-167.
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  60. Obochi, G.O., S.P. Malu, A.E. Abara, V.S. Ekam, F.U. Uboh and M. Obi-Abang, 2009. Effects of ascorbate on monosodium glutamate-associated toxicities that may impact upon immunocompetence. Toxicol. Environ. Chem., 91: 547-557.
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  61. Akpanabiatu, M.I., F.E. Uboh, T.B. Ekanem, I.B. Umoh, E.U. Eyong and S.O. Ukafia, 2009. The effect of interaction of rauwolfia vomitoria root bark extract with vitamin E on rats liver enzymes. Turk. J. Biol., 33: 189-194.
    Direct Link  |  

  62. Uboh, F.E., P.E. Ebong, E. Oton, I.H. Itam and N. Barnaby, 2008. Antioxidant vitamins and free radical status in Nigerian pre-eclamptic women. Res. J. Obstet. Gynecol., 1: 30-33.
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  63. Uboh, F.E., M.I. Akpanabiatu, P.M.U. Eteng, E. Ebong and I.B. Umoh, 2008. Toxicological effects of exposure to gasoline vapours in male and female rats. Int. J. Toxicol., 4: 40-45.

  64. Uboh, F.E., M.I. Akpanabiatu, I.J. Atangwho, P.E. Ebong and I.B. Umoh, 2008. Effect of vitamin A on weight-loss and haematotoxicity associated with gasoline vapours exposure in Wistar rats. Int. J. Pharmacol., 4: 40-45.
    CrossRef  |  Direct Link  |  

  65. Uboh, F.E., M.I. Akpanabiatu, I.J. Atangwho and Y. Alozie, 2008. Exposure to gasoline vapours: A potential risk factor for atherosclerosis in male and female rats. J. Pharmacol. Toxicol., 3: 600-609.
    CrossRef  |  Direct Link  |  

  66. Uboh, F.E., M.I. Akpanabiatu and Y. Alozie, 2008. Comparative effect of gasoline vapours on renal functions in male and female albino wistar rats. J. Pharmacol. Toxicol., 3: 478-484.
    CrossRef  |  Direct Link  |  

  67. Uboh, F.E., M.I. Akpanabiatu, P.E. Ebong and I.B. Umoh, 2007. Gender differences in the haematotoxicity and weight changes associated with exposure to gasoline vapours in wistar albino rats. Acta Toxicol., 15: 125-131.
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  68. Uboh, F.E., M.I. Akpanabiatu, I.S. Ekaidem, P.E. Ebong and I.B. Umoh, 2007. Effect of inhalation exposure to gasoline on sex hormones profile in wistar albino rats. Acta Endocrinol., 3: 23-30.
    Direct Link  |  

  69. Uboh, F.E., M.I. Akpanabiatu, I.J. Atangwho, P.E. Ebong and I.B. Umoh, 2007. Effect of gasoline vapours on serum lipid profile and oxidative stress in hepatocytes of male and female rats. Acta Toxicol., 15: 25-30.
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  70. Obochi, G.O., A.E. Abara, S.P. Malu, V.S. Ekam, F.U. Uboh and I.B. Umoh, 2007. Effect of alcohol and kolanut interaction on biochemical indices of neuronal gene expression in wistar albino rats. Niger. J. Physiol. Sci., 22: 69-73.

  71. Ekaidem, I.S., M.I. Akpanabiatu, F.E. Uboh and O.U. Eka, 2007. Effect of folic acid and vitamin B12 administration on phenytoin induced toxicity in rats. Indian J. Clin. Biochem., 22: 36-40.
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  72. Atangwho, I.J., P.E. Ebong, E.U. Eyong, M.U. Eteng and F.E. Uboh, 2007. Vernonia amygdalina del: A potential prophylactic anti-diabetic agent in lipid complication. Global J. Pure Applied Sci., 13: 103-106.
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  73. Abara, A.E., G.O. Obochi, S.P. Malu, M. Obi-Abang, V.S. Ekam and F.U. Uboh, 2007. Effect of caffeine-coconut products interactions on induction of microsomal drug-metabolizing enzymes in wistar albino rats. Niger. J. Physiol. Sci., 22: 75-81.

  74. Eteng, M.U., H.A. Ibekwe, T.E. Amatey, B.J. Bassey, F.U. Uboh and D.U. Owu, 2006. Effect of vitamin C on Serum lipids and electrolyte profile of Albino Wistar Rats. Niger. J. Physiol. Sci., 21: 15-19.
    PubMed  |  Direct Link  |  

  75. Ekaidem, I.S., M.I. Akpanabiatu, F.E. Uboh and O.U. Eka, 2006. Vitamin B12 supplementation: Effects on some biochemical and haematological indices of rats on Phenytoin administration. Biokemistri, 18: 31-37.
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  76. Akpanabiatu, M.I., I.B. Umoh, F.E. Uboh and E.O. Udosen, 2006. Effect of nauclea latifolia leaf extracts on some rats serum enzymes of clinical significance. Recent Prog. Med. Plants, 14: 298-304.

  77. Akpanabiatu, M.I., I.B. Umoh, E.U. Eyong, E.E. Edet and F.E. Uboh, 2006. Influence of rauwolfia vomitoria root bark extract on cardiac enzymes of normal wistar albino rats. Recent Prog. Med. Plants, 14: 273-278.

  78. Uboh, F.E., P.E. Ebong, O.U. Eka, E.U. Eyong and M.I. Akpanabiatu, 2005. Effect of inhalation exposure to kerosene and petrol-fumes on some anaemia-diagnostic indices in rats. Global J. Environ. Sci., 3: 59-63.
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  79. Uboh, F.E., M.I. Akpanabiatu, P.E. Ebong, E.U. Eyong and I.S. Ekaidem, 2005. Evaluation of toxicological implications of inhalation exposure to kerosene fumes and petrol fumes in rats. Acta Biol. Szegiendiensis, 49: 19-22.
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