Dr. Mohammed Hussen Bule
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Dr. Mohammed Hussen Bule

Assistant Professor
Department of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia

Highest Degree
Ph.D. in Medicinal Chemistry from Tehran University of Medical Sciences, Tehran, Iran

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Area of Interest:

Biomedical Sciences
Drug Discovery
Antidiabetic Activity
Natural Product Chemistry

Research Publications in Numbers


Selected Publications

  1. Zaplatic, E., M. Bule, S.Z.A. Shah, M.S. Uddin and K. Niaz, 2019. Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease. Life Sci., 224: 109-119.
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  2. Shah, T., M. Bule and K. Niaz, 2019. Goji Berry (Lycium barbarum)—A Superfood. In: Nonvitamin and Nonmineral Nutritional Supplements, Nabavi, S.M. and A.S. Silva (Eds.). Chapter 3.21, Academic Press, New York, USA., ISBN: 978-0-12-812491-8, pp: 257-264.
  3. Shah, T., F. Khan, M. Bule and K. Niaz, 2019. White Dead-Nettle (Lamium album). In: Nonvitamin and Nonmineral Nutritional Supplements, Nabavi, S.M. and A.S. Silva (Eds.). Chapter 3.44, Academic Press, New York, USA., ISBN: 978-0-12-812491-8, pp: 455-459.
  4. Khan, I.T., M. Bule, R. Ullah, M. Nadeem, S. Asif and K. Niaz, 2019. The antioxidant components of milk and their role in processing, ripening and storage: Functional food. Vet. World, 12: 12-33.
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  5. Bule, M., F. Khan and K. Niaz, 2019. Red Yeast Rice (Monascus purpureus). In: Nonvitamin and Nonmineral Nutritional Supplements, Nabavi, S.M. and A.S. Silva (Eds.). Chapter 5.2, Academic Press, New York, USA., ISBN: 978-0-12-812491-8, pp: 509-515.
  6. Bule, M., A. Abdurahman, S. Nikfar, M. Abdollahi and M. Amini, 2019. Antidiabetic effect of quercetin: A systematic review and meta-analysis of animal studies. Food Chem. Toxicol., 125: 494-502.
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  7. Abdurahman, A.A., M. Bule, L. Azadbakhat, M. Fallahyekta, A. Parouhan, M. Qorbani and A.R. Dorosty, 2019. The association between diet quality and obesity-related metabolic risks. Hum. Antibodies, (In Press). 10.3233/HAB-190387.
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  8. Abdurahman, A.A., E.E. Chaka, M.H. Bule and K. Niaz, 2019. Magnitude and determinants of complementary feeding practices in Ethiopia: A systematic review and meta-analysis. Heliyon, Vol. 5, No. 7. 10.1016/j.heliyon.2019.e01865.
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  9. Tiwari, R., S.K. Latheef, I. Ahmed, H.M.N. Iqbal and M.H. Bule et al., 2018. Herbal Immunomodulators-A remedial panacea for designing and developing effective drugs and medicines: Current scenario and future prospects. Curr. Drug Metab., 19: 264-301.
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  10. Bule, M.H., I. Ahmed, F. Maqbool, M. Bilal and H.M.N. Iqbal, 2018. Microalgae as a source of high-value bioactive compounds. Front. Biosci., 10: 197-216.
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  11. Ahmed, I., Z. Akram, M.H. Bule and H.M.N. Iqbal, 2018. Advancements and potential applications of microfluidic approaches-a review. Chemosensors, Vol. 6, No. 4. 10.3390/chemosensors6040046.
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  12. Mengesha, H.G., T.B. Tafesse and M.H. Bule, 2017. If channel as an emerging therapeutic target for cardiovascular diseases: A review of current evidence and controversies. Front. Pharmacol., Vol. 8. 10.3389/fphar.2017.00874.
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  13. Bule, M.H., I. Ahmed, F. Maqbool and M.A. Zia, 2017. Quinazolinone derivatives as a potential class of compounds in malaria drug discovery. Int. J. Pharmacol., 13: 818-831.
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  14. Bule, M.H., F. Maqbool, I. Ahmed, K. Dhama and H.M.N. Iqbal, 2017. Advances in the treatment options towards drug-resistant tuberculosis. Int. J. Pharmacol., 13: 746-761.
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  15. Bule, M.H., B.A. Hamido, T.S. Chala and G.T. Kefeni, 2016. Knowledge, attitudes and practices of healthcare professionals towards adverse drug reaction reporting in Adama hospital medical college, East Shoa zone, Oromia regional state, Ethiopia. Pharma Innov., 5: 24-28.
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  16. Kefeni, G.T., M.H. Bule, A. Hymete and A.A. Bekhit, 2015. Design, synthesis and in-vivo biological activity testing of 2, 3-disubstituted 4(3H)-quinazolinone derivatives as anti-malarial agents. Eur. J. Biomed. Pharmaceut. Sci., 2: 371-382.
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  17. Issa, I.A. and M.H. Bule, 2015. Hypoglycemic effect of aqueous and methanolic extract of Artemisia afra on alloxan induced diabetic Swiss albino mice. Evidence-Based Complement. Altern. Med., Vol. 2015. 10.1155/2015/752486.
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  18. Issa, I.A. and M.H. Bule, 2015. A comparative study of the hypoglycemic effect of aqueous and methanolic extracts of Myrtus communis on alloxan induced diabetic Swiss albino mice. Med. Aromat. Plants, Vol. 4. 10.4172/2167-0412.1000190.
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  19. Haile, F.E., M.H. Bule, B.K. Gelaw, G.T. Tegegne and A.D. Defersha, 2015. Anti-diabetic medication pattern in Adama hospital medical college East Shoa Zone, Oromia, Ethiopia. Int. J. Pharma Sci., 5: 1200-1208.
  20. Chala, T.S., H. Gebramariam and M. Hussen, 2015. Two-year epidemiologic pattern of acute pharmaceutical and chemical poisoning cases admitted to Adama hospital medical college, Adama, Ethiopia. Asia Pac. J. Med. Toxicol., 4: 106-111.
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  21. Bule, M.H., A. Haymete and B. Kefale, 2015. Synthesis and in-vivo pharmacological evaluation of some novel 4(3h)-quinazolinone derivatives as potential anti-malarial agents. Indo Am. J. Pharmaceut. Res., 5: 963-971.
  22. Bayisa, T.K., M.H. Bule and J.L. Lenjisa, 2015. The potential of nano technology based drugs in lung cancer management. Pharma Innov., 4: 77-81.
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  23. Aliyi, O., M. Hussien and B. Kefale, 2015. Problems of using hydrochlorothiazide diuretic in adult diabetic patient in diabetic clinic of Adama Hospital Medical College, East Shoa Zone, Oromia Regional State, Ethiopia. Clin. Pharmacol. Biopharmaceut., Vol. 4. 10.4172/2167-065X.1000134.
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