Dr. Mathew Piero Ngugi
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Dr. Mathew Piero Ngugi

Senior Lecturer
Department of Biochemistry, Microbiology and BiotechnologyKenyatta University, Kenya

Highest Degree
Ph.D. in Molecular Biology from Kenyatta University, Kenya

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Area of Interest:

Molecular Sciences
100%
Applied Pharmacology
62%
Molecular Biology
90%
Natural Production
75%
Metabolism
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Mworia, J.K., C.M. Kibiti, J.J.N. Ngeranwa and M.P. Ngugi, 2021. Anti-inflammatory potential of dichloromethane leaf extracts of Eucalyptus globulus (Labill) and Senna didymobotrya (Fresenius) in mice. Afr. Health Sci., 21: 397-409.
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  2. Mwangi, J.W., O.R. Okoth, M.P. Kariuki and N.M. Piero, 2021. Genetic and phenotypic diversity of selected Kenyan mung bean (Vigna radiata L. Wilckzek) genotypes. J. Genet. Eng. Biotechnol., Vol. 19. 10.1186/s43141-021-00245-9.
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  3. Mwaeni, V.K., J.N. Nyariki, N. Jillani, G. Omwenga, M. Ngugi and A.O. Isaac, 2021. Coenzyme Q10 protected against arsenite and enhanced the capacity of 2,3-dimercaptosuccinic acid to ameliorate arsenite-induced toxicity in mice. BMC Pharmacol. Toxicol., Vol. 22. 10.1186/s40360-021-00484-z.
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  4. Muindi, H.M., C.M. Kibiti and M.P. Ngugi, 2021. Hemoglobin precipitation: An index of in vitro vasoconstrictive activities of methanol leaf extracts of Croton megalocarpus hutch and Lantana camara Linn. Evidence-Based Complement. Altern. Med., Vol. 2021. 10.1155/2021/3817106.
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  5. Muindi, H., C. Kibiti and M. Ngugi, 2021. Hemostatic activities of methanol leaf extracts of Croton megalocarpus Hutch and Lantana camara Linn. J. Adv. Biotechnol. Exp. Ther., 4: 215-222.
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  6. Moriasi, G.A., A.M. Ireri, E.M. Nelson and M.P. Ngugi, 2021. In vivo anti-inflammatory, anti-nociceptive, and in vitro antioxidant efficacy, and acute oral toxicity effects of the aqueous and methanolic stem bark extracts of Lonchocarpus eriocalyx (Harms.). Heliyon, Vol. 7. 10.1016/j.heliyon.2021.e07145.
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  7. Moriasi, G., C. Kibiti and M. Ngugi, 2021. In vivo antidiabetic efficacy, mineral element composition, and qualitative phytochemistry of the aqueous leaf extracts of Pentas zanzibarica (Klotzsch.) Vatke and Olea europaea subspecies africana (Mill.). J. Adv. Biotechnol. Exp. Ther., 4: 334-348.
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  8. Kimuni, S.N., S.M. Gitahi, E.M. Njagi and M.P. Ngugi, 2021. Antinociceptive potential of methanol leaf extracts of Cissampelos parreira (Linn), Lantana camara (Linn) and Ocimum gratissimum (African basil). J. Adv. Biotechnol. Exp. Ther., 4: 349-364.
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  9. Gitahi, S.M., M.P. Ngugi, D.N. Mburu and A.K. Machocho, 2021. Contact toxicity effects of selected organic leaf extracts of Tithonia diversifolia (Hemsl.) A. Gray and Vernonia lasiopus (O. Hoffman) against Sitophilus zeamais Motschulsky (Coleoptera: Curculionidae). Int. J. Zool., 10.1155/2021/8814504.
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  10. Bicko, S.J., M. Cecilia, P. Mathew and M. Wilton, 2021. CRISPR/Cas genome editing: A frontier for transforming precision cassava breeding. Afr. J. Biotechnol., 20: 237-250.
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  11. Akimat, E.K., G.I. Omwenga, G.A. Moriasi and M.P. Ngugi, 2021. Antioxidant, anti-inflammatory, acute oral toxicity, and qualitative phytochemistry of the aqueous root extract of Launaea cornuta (Hochst. Ex Oliv. & Hiern.). J. Evidence-Based Integr. Medicine., Vol. 26. 10.1177/2515690X211064585.
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  12. Moriasi, G.A., A.M. Ireri and M.P. Ngugi, 2020. In vivo cognitive-enhancing, Ex vivo malondialdehyde-lowering activities and phytochemical profiles of aqueous and methanolic stem bark extracts of Piliostigma thonningii (schum.). Int. J. Alzheimer's Dis., 2020: 1-15.
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  13. Ngari, L.N., S.N. Njagi, J.K. Kamau, R.C. Lagat and A.M. Musyoki, 2019. Phenotypic characterization of selected Kenyan Khat (Catha edulis) cultivars based on morphological traits. Afr. J. Biotechnol., 18: 865-874.
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  14. Limbua, P.G., M.P. Ngugi and R.O. Oduor, 2019. In vitro regeneration protocol of kenyan adapted groundnut (Arachis hypogaea L.) genotypes using cotyledonary node explants. J. Plant Biochem. Physiol., 07: 1-4.
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  15. Arika, W.M., C.M. Kibiti, J.M. Njagi and M.P. Ngugi, 2019. Effects of DCM leaf extract of Gnidia glauca (Fresen) on locomotor activity, anxiety, and exploration-like behaviors in high-fat diet-induced obese rats. Behav. Neurol., 2019: 1-14.
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  16. Arika, W.M., C.M. Kibiti, J.M. Njagi and M.P. Ngugi, 2019. Anti-obesity effects of dichloromethane leaf extract of Gnidia glauca in high fat diet-induced obese rats. Heliyon, 10.1016/j.heliyon.2019.e02800.
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  17. Alex, N., M. Cecilia, N. Mathew, M. Asunta, O. Henry and M. Wilton, 2018. Efficient plant regeneration protocol for finger millet [Eleusine coracana (L.) Gaertn.] via somatic embryogenesis. Afr. J. Biotechnol., 17: 660-667.
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  18. Ouko, R.O., S.C. Koech, W.M. Arika, S.M. Njagi, Oduor R.O. and M.P. Ngugi, 2017.. Bioefficacy of organic extracts of ocimum basilicum against sitophilus zeamais. Entomol. Ornithol. Herpetol., .
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  19. Musila, M.N., D.N. Ngai, J.W. Mbiri, S.M. Njagi, W.M. Mbinda and M.P. Ngugi 2017. Acute and sub-chronic oral toxicity study of methanolic extract of caesalpinia volkensii (harms). J. Drug Meta. Toxicol., 10.4172/2157-7609.1000222.
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  20. Muia P.K., M.P. Ngugi, D.N. Mburu, 2017. Performance of genexpert assay in detecting pulmonary tuberculosis and rifampicin resistance in patients attending kitui county hospital, Kenya. J. Trop. Dis., 05: 1-8.
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  21. Koech, S.C., R.O. Ouko, N.M. Michael, M.M. Ireri, M.P. Ngugi and N.M. Njagi, 2017. Analgesic activity of dichloromethanolic root extract of clutia abyssinica in swiss albino mice. Nat. Product Chem. Res., 10.4172/2329-6836.1000255.
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  22. Koech, S.C., A.V. Sindani, J.B. Maoga and M.P. Ngugi, 2017. Anti-pyretic potential of dichloromethanolic root extract of clutia abyssinica in wistar albino rats. Med. Aromat. Plant, 10.4172/2167- 0412.1000281.
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  23. Kariuki, D.M., D.M. Gaichu, D.N. Mburu and M.P. Ngugi, 2017. In vivo safety of dichloromethane-methanolic extract of allium sativum in normal mice. J. Drug Meta. Toxicol., 10.4172/2157-7609.1000223.
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  24. Osano, K.O., D.W. Nyamai, P. Ogola and M.P. Ngugi, 2016. Evaluation of in vivo toxicity of dichloromethane: Methanolic leaf extracts of prosopis juliflora in female wistar albino rats. J. Drug Metab. Toxicol., 10.4172/2157-7609.1000200.
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  25. Ogola, P., W. Arika, D.W. Nyamai and R. Odour, 2016. Determination of background ionizing radiations in selected buildings in nairobi county, kenya. Nucl. Med. Radiat. Therapy, 10.4172/2155-9619.1000289.
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  26. Nthiga, P.M., J.K. Kamau, V.Z. Safari, J.K. Mwonjoria, D.N. Mburu and M.P. Ngugi, 2016.. Antipyretic potential of methanolic stem bark extracts of harrisonia abyssinica oliv and landolphia buchananii (Hallier f.) stapf in wistar rats. J. Appl. Pharm., 10.4172/1920-4159.1000227.
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  27. Nthiga P., J.K. Kamau, V.Z. Safari and D. Mburu, 2016. Antinociceptive activity of methanolic stem bark extracts of harrisonia abyssinica oliv and landolphia buchananii (Hallier f.) stapf in mice model. J. Pain Rel., 10.4172/2167-0846.1000253.
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  28. Njagi, S.M., R.C. Lagat, A.M. Mawia, W.M. Arika and F.K. Wambua, 2016. In vitro antiproliferative activity of aqueous root bark extract of cassia abbreviata (Holmes) brenan. J. Cancer Sci. Therapy, 8: 114-121.
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  29. Matheri, F., M. Mwangi, S. Runo, M. Ngugi and D.T. Kirubi, et al. 2016. Phenotypic characterization of selected kenyan purple and yellow passion fruit genotypes based on morpho-agronomic descriptors. Adv. Crop Sci. Technol., 10.4172/2329-8863.1000226.
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  30. Matheri, F., F. Teya, F. Kioko and S. Runo, 2016. Genotyping of kenyan passiflora edulis flavicarpa hybrid accessions and their parents using ssr markers. Vegetos, 10.4172/2229-4473.1000181.
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  31. Matheri, F., D. Nyamai, M.P. Ngugi, S. Runo, J.K. Njuguna, M. Mwangi and D.T. Kirubi, 2016. Phenotyping of selected kenyan passiflora edulis varieties and their hybrids based on quantitative morpho-agronomic traits. J. Hort., 10.4172/2376-0354.1000181.
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  32. Marigi, E.N., J.O. Masanga, T.L. Munga, L.S. Karanja and M.P. Ngugi, 2016. Optimisation of a somatic embryogenesis and transformation protocol for farmer-preferred cassava cultivars in kenya. African Crop Sci. J., 24: 35-44.
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  33. Kamau, J.K., P.M. Nthiga, V.C. Safari, S.M. Njagi, J.K. Mwonjoria, M.P. Ngugi and J.J.N. Ngeranwa, 2016. Antipyretic properties of methanol stem bark extracts of acacia hockii de wild and kigelia africana (lam) benth in wistar rats. J. Pharm. Nat. Prod., 10.4172/2472-0992.1000118.
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  34. Kamau ,J.K., P.M. Nthiga, J.K. Mwonjoria, J.J.N. Ngeranwa and M.P. Ngugi, 2016. Anti-inflammatory activity of methanolic leaf extract of kigelia africana (lam.) benth and stem bark extract of acacia hockii de wild in mice. J. Devel. Drugs, 10.4172/2329-6631.1000156.
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  35. Jorum, O.H., N.M. Piero and A.K. Machocho, 2016. Haematological effects of dichloromethane-methanolic leaf extracts of Carissa edulis (Forssk.) Vahl in normal rat models. J. Hematol. Thromboembolic Dis., Vol. 4. 10.4172/2329-8790.1000232.
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  36. Jorum, O.H., A.K. Machocho and N.M. Piero, 2016. Effects of dichloromethane-methanolic leaf extracts of carissa edulis (Forssk) vahl on serum lipid profiles in normal rat models. J. Hypertension, 10.4172/2167-1095.1000217.
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  37. Chemutai, L.R., M.A. Musyoki, W.F. Kioko, N.S. Mwenda, K.G. Muriira and N.M. Piero, 2016. Genetic diversity studies on selected rice (oryza sativa l.) genotypes based on gel consistency and alkali digestion. J. Rice Res., 10.4172/2375-4338.1000172.
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  38. Chemutai, L.R., M.A. Musyoki, W.F. Kioko, N.S. Mwenda, K.G Muriira and N.M. Piero, 2016. Physicochemical characterization of selected rice (oryza sativa l.) genotypes based on gel consistency and alkali digestion. Biochem. Anal. Biochem., 10.4172/2161-1009.1000285.
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  39. Arika, W.M., P.E. Ogola, D.W. Nyamai, A.M. Mawia, F.K. Wambua, et al. 2016. Mineral elements content of selected kenyan antidiabetic medicinal plants. Adv. Tech. Biol. Med., 10.4172/2379-1764.1000160.
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  40. Arika, W.M., H.O. Rachuonyo, A.N. Muchori, R.C. Lagat and A.M. Mawia,et al. 2016. Hypoglycemic effect of ocimum lamiifolium in alloxan induced diabetic mice. Med. Arom. Plants, 10.4172/2167-0412.1000228.
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  41. Arika, W.M., D.W. Nyamai, M.N. Musila, M.P. Ngugi and E.N.M. Njagi, 2016. Hematological markers of in vivo toxicity. J. Hematol. Thromboembolic Dis., 10.4172/2329-8790.1000236.
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  42. Arika, W.M., D.W. Nyamai, D.S. Agyirifo, M.P. Ngugi and E.N.M. Njagi, 2016. In vivo antidiabetic effect of aqueous leaf extract of azardirachta indica, a. juss in alloxan induced diabetic mice. J. Diabetic Complications Med., 10.4172/2475-3211.1000106.
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  43. Anne, N.W., M.P. Piero, A. Umar, M. Felix and N.G. Mutero, 2016. In vitro anti-acetylcholinesterase activity of dichloromethane leaf extracts of carphalea glaucescens in chilo partellus larvae. Biochem. Anal. Biochem., 10.4172/2161-1009.1000264.
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  44. Umar, A., N.M. Piero, A.J. Mgutu, N.W. Ann and G.S. Maina,et al. 2015. Bio efficacy of aqueous crude fruit sap extract of solanum incanum against green peach aphids myzus persicae sulzer (Homoptera: Aphididae). Entomol. Ornithol. Herpetol., 10.4172/2161-0983.1000169.
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  45. Umar, A., A.J. Mgutu, N.M. Piero, N.W. Ann and G.S. Maina,et al. 2015. In vitro anti-acetylcholinesterase activity of crude fruits sap extract of solanum incanum in green peach aphids. J. Developing Drugs, 4: 142-145.
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  46. Piero, N.M., N.S. Kimuni, N.J. Ngeranwa, O.G. Orinda and M.J. Njagi, 2015. Antidiabetic and safety of lantana rhodesiensis in alloxan induced diabetic rats. Develop. Drugs, 10.4172/2329-6631.1000129.
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  47. Piero, N.M., N.N.M. Eliud, K.N. Susan, O.O. George, N.J. Murugi, et al 2015. In vivo antidiabetic activity and safety in rats of cissampelos pareira traditionally used in the management of diabetes mellitus in embu county, kenya. J. Drug Metab. Toxicol., 6: 184-194.
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  48. Piero, N.M., N.M. Joan, O.O. Richard, A.M. Jalemba, R.O. Omwoyo and R.C. Chelule, 2015. Determination of cyanogenic compounds content in transgenic acyanogenic kenyan cassava (manihot esculenta crantz) genotypes: Linking molecular analysis to biochemical analysis. Anal. Bioanal. Tech., 6: 264-271.
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  49. Piero, N.M., N.J. Murugi, O.R. Okoth, O.R. Ombori, M.A. Jalemba and C.R. Chelule, 2015. Rnai-Mediated downregulation of cyano-glycoside biosynthesis in kenyan cassava (manihot esculenta crantz) genotypes. Plant Biochem. Physiol., 3: 148-153.
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  50. Piero, N.M. and N.M. Joan, 2015. Cancer: a molecular curse. Int. J. Current Pharm. Res., 7: 1-3.
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  51. Ngugi, M.P., R.O. Oduor, R.O. Omwoyo, J.M. Njagi, A.J. Mgutu and R.C. Cheruiyot 2015. Regeneration of kenyan cassava (manihot esculenta crantz) genotypes. Plant Biochem. Physiol., 10.4172/2329-9029.1000147.
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  52. Mworia, J.K., S.M. Gitahi, K.K. Juma, J.M. Njagi and B.M. Mwangi,et al. 2015. Antinociceptive activities of acetone leaves extracts of carissa spinarum in mice. Med. Aromatic Plants, 10.4172/2167-0412.S1-006.
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  53. Mworia, J.K., K.K. Juma, J.M. Njagi, B.M. Mwangi and U. Aliyu,et al. 2015. Analgesic potential of acetone leaf extract of caesalpinia volkensii harms in mice. Pharm. Anal. Acta, 6: 450-455.
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  54. Musyoki, M.A., W.F. Kioko, N.P. Mathew, K.G. Muriira and N.D. Wavinya,et al. 2015. Genetic diversity studies on selected rice (Oryza sativa l.) genotypes based on amylose content and gelatinization temperature. Adv. Crop Sci. Biotechnol., 3: 193-199.
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  55. Musyoki, M.A., F. Wambua, A. Daniel, N.D. Wavinya and M. Felix, et al. 2015. Phenotypic diversity studies on selected kenyan and tanzanian rice (Oryza sativa l) genotypes based on grain and kernel traits. J. Rice Res., 3: 150-154.
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  56. Muriithi, N.J., G.S. Maina, N.M. Mugendi, M.B. Maina and M.J. Kiambi,et al. 2015. Determination of hematological effects of methanolic leaf extract of s. incanum in normal mice. Pharm. Anal. Acta, 6: 429-435.
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  57. Maina, M.B., G.S. Maina, N.J. Muriithi1, M.J. Kiambi and A. Umar et al, 2015. Antinociceptive properties of dichloromethane:methanolic leaf extracts of caesalpinia volkensii and maytenus obscura in animal models..Int. J. Current Pharm. Res., 7: 83-87.
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  58. Maina, M.B., G.S. Maina, N.J. Muriithi, M.J. Kiambi and A. Umar,et al. 2015. Antinociceptive properties of dichloromethane:Methanolic leaf extracts of caesalpinia volkensii and maytenus obscura in animal models. J. Pain Relief, 4: 191-196.
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  59. Maina, G.S., M.B. Maina, N.J. Muriithi, M.J. Kiambi and J.K. Kelvin et al, 2015. Antipyretic properties of dichloromethane: Methanolic leaf and root bark extracts of carissa edulis in rats. Asian. J. Biomed. Pharm. Sci., 5: 12-20.
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  60. Maina, G.S., J.K. Kelvin, M.B. Maina, N.J. Muriithi and M.J. Kiambi et al. 2015. Antinociceptive properties of dichloromethane: Methanolic leaf and root bark extracts of Carissa edulis in rats. J. Phytopharmacol., 4: 106-112.
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  61. Kioko, W.F., M.A. Musyoki, N.M. Piero, K.G. Muriira and N.D. Wavinya, et al. 2015. Genetic diversity studies on selected rice (Oryza sativa l) populations based on aroma and cooked kernel elongation. J. Phylogenet. Evol. Biol., 3: 158-164.
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  62. Kioko, W.F., M.A. Mawia, N.M. Piero, K.G. Muriira and N.D. Wavinya, 2015. Phenotypic characterization on selected kenyan and tanzanian rice (Oryza sativa l) populations based on grain morphological traits. J. Rice Res., 3: 155-161.
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  63. Juma, K.K., R.M.J. Fulakeza, J.N. Ngeranwa, M.P. Ngugi and N.D. Mburu, 2015. Evidence based phytopharmacological potential of herbal extracts in post- ingestion management of mycotoxins in animal models. Clin. Toxicol., 5: 254-262.
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  64. Arika, W.M., Y.A. Abdirahman, M.M. Mawia, K.F. Wambua and D.M. Nyamai,et al. 2015. Hypoglycemic effect of lippia javanica in alloxan induced diabetic mice. J. Diabetes Metab., 6: 624-630.
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  65. Arika, W.M., Y.A. Abdirahman, M.A. Mawia, K.F. Wambua and D.M. Nyamai,et al. 2015. In vivo antidiabetic activity of the aqueous leaf extract of croton macrostachyus in alloxan induced diabetic mice. Pharm. Anal. Acta, 6: 447-452.
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  66. Arika, W.M., P.E. Ogola, Y.A. Abdirahman, A.M. Mawia and F.K. Wambua,et al. 2015. In vivo safety of aqueous leaf extract of lippia javanica in mice models. Biochem. Physiol., 5: 191-200.
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  67. Abdirahman, Y.A., K.K. Juma, M.J. Mukundi, S.M. Gitahi and D.S. Agyirifo,et al, 2015. The hypoglycemic activity and safety of aqueous stem bark extracts of acacia nilotica. J. Drug Metab. Toxicol., 6: 189-198.
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