Dr. Christos   C. Zouboulis
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Dr. Christos C. Zouboulis

Professor
Freie Universitaet Berlin, Germany


Highest Degree
M.D. in Dermatology from University of Athens, Greece

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Biography

Prof. Dr. med. Prof. h.c. Dr. h.c. Christos Zouboulishas studied medicine and political sciences at the National and Kapodistrian University of Athens, Greece. He performed his pre-doctoral work on cell biology at the Department of Dermatology, Benjamin Franklin Medical Center, Freie Universitaet Berlin, Germany where he was awarded his thesis title (Dr. med.) in 1988. He further continued his postgraduate medical education and completed the residencies in Dermatology and Venereology as well as in Allergology at the same department. Subsequently, he joined the Department of Dermatology, University of Michigan Medical Center, Ann Arbor, MI, USA for a research fellowship on molecular biology, and the Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA as well as the Department of Dermatology, Massachusetts General Hospital, Harvard University, Boston, MA, USA for clinical research before returning as faculty at the Department of Dermatology, FreieUniversitaet Berlin, where he accomplished his habilitation thesis (Priv.-Doz.) in 1995. In 2000, he was named Professor of Dermatology and Venereology of the FreieUniversitaet Berlin, where he served as Vice Chair of the Department of Dermatology from 2000 to 2005. In 2005 he was elected Director of the Departments of Dermatology, Venereology, Allergology and Immunology at the Dessau Medical Center, Dessau, Germany and in 2016 Founding Professor of Dermatology and Venereology at the Theodor Fontane Medical University of Brandenburg, Germany. Prof. Zouboulis is currently the Editor of the European Academy of Dermatology and Venereology (EADV) News, Co-Editor of Dermato-Endocrinology and Rejuvenation Research and serves in the Editorial Boards of several leading international scientific journals.He has received numerous awards for his scientific work, including the Oskar Gans Prize of the German Dermatological Society, the EADV Research Fellowship, the Felix Wankel Animal Protection Research Prize, the Paul Gerson Unna Prize on immunological research and the Springer Prize for Dermatology. His Departments have been decorated with the title "Germany land of ideas - 2009 place of excellence" for the work on skin stem cell biology.Prof. Zoubouliswas elected Prof. h.c. of the University of Franche-Comte, BesanÒon, France, Dr. h.c. of the National and KapodistrianUniversity of Athens and Visiting Professor of the Jiao Tong University of Shanghai, China. He is honorary member of the French, the Hungarian and the Lithuanian Dermatological Societies. He currently serves as President of the European Hidradenitis Foundation (EHSF) e.V.,as Honorary President of the European Society of Preventive, Regenerative and Anti-Aging Medicine (ESAAM) after a 10-year active presidency, and as Board member of the EADV and the International Society on BehÒet’s Disease. Prof. Zouboulishas performed fundamental research - among other fields - on Dermato-Endocrinology and sebaceous glands, acne, hidradenitissuppurativa/acne inversa, skin stem cells, molecular ageing, dermato-pharmacology, cryosurgery, and rare diseases incl. Adamantiades-BehÒet`s disease. He is the author of more than 700 publications (cumulative impact factor 1414, h index 77), has given over 500 invited lectures, has organized numerous conferences and is owner on five patents, including one for the SZ95 sebaceous gland cell line, an in vitro model for acne, aging and lipid research. He has first described the flashing pulsating angioma and the trias of keratosis pilaris,ulerythemaophryogenes and 18p monosomy, whereas the latter has been confirmed by several other authors and has been proposed as “Zouboulis syndrome”.

Area of Interest:

Medicine
100%
Surgery
62%
Gerontology
90%
Dermatology
75%
Pharmacology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Zouboulis, C.C., H. Seltmann, M.B. Abdel-Naser, A.M. Hossini, G.K. Menon and R. Kubba, 2017. Effects of extracellular calcium and 1,25 dihydroxyvitamin D3 on sebaceous gland cells in vitro and in vivo. Acta Derm. Venereol., Vol. 97. .
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  2. Crivellari, I., C. Sticozzi, G. Belomonte, X.M. Muresan and F. Cervellati et al., 2017. SRB1 as a new redox target of cigarette smoke in human sebocytes. Free Radic. Biol. Med., 102: 47-56.
  3. Zouboulis, C.C., Y. Har-Shai and C.E. Orfanos, 2016. Cryosurgical Treatment of Keloids and Hypertrophic Scars. In: Dermatological Cryosurgery and Cryotherapy, Abramovits, W., G. Graham, Y. Har-Shai and R. Strumia (Eds.)., Springer, London, pp: 413-451.
  4. Zouboulis, C.C., 2016. Is cryosurgery less effective that conservative regimens in the treatment of actinic keratoses? J. Eur. Acad. Dermatol. Venereol., 30: e50-e53.
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  5. Olah, A., A. Markovics, J. Szabo-Papp, P.T. Szabo, C. Stott, C.C. Zouboulis and T. Biro, 2016. Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment. Exp. Dermatol., 25: 701-707.
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  6. Okoro, E.O., N.G. Bulus and C.C. Zouboulis, 2016. Study of facial sebum levels and follicular red fluorescence in patients with acne vulgaris in Nigeria. Dermatology, 232: 156-161.
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  7. Nikolakis, G., E. Makrantonaki and C.C. Zouboulis, 2016. Aging Skin: A Window to the Body. In: Skin Aging and Age-Related Disorders, Quan, T. (Ed.)., Science Publishers, Boca Raton, pp: 200-228.
  8. Makrantonaki, E., E. Steinhagen-Thiessen, R. Nieczaj, C.C. Zouboulis and R. Eckardt, 2016. Prevalence of skin diseases in hospitalized geriatric patients: Association with gender, duration of hospitalization and geriatric assessment. Zeitschrift Gerontologie Geriatrie, (In Press). 10.1007/s00391-016-1084-3.
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  9. Liakou, A.I., J.R. Nyengaard, S. Bonovas, J. Knolle, E. Makrantonaki and C.C. Zouboulis, 2016. Marked reduction of the number and individual volume of sebaceous glands in psoriatic lesions. Dermatology, 232: 415-424.
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  10. Kovacs, D., M. Lovaszi, S. Poliska, A. Olah and T. Biro et al., 2016. Sebocytes differentially express and secrete adipokines. Exp. Dermatol., 25: 194-199.
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  11. Kimball, A.B., M.M. Okun, D.A. Williams, A.B. Gottlieb and K.A. Papp et al., 2016. Two phase 3 trials of adalimumab treatment of hidradenitis suppurativa. N. Engl. J. Med., 375: 422-434.
  12. Kimball, A.B., J.M. Sobell, C.C. Zouboulis, Y. Gu and D.A. Williams et al., 2016. HiSCR (Hidradenitis Suppurativa Clinical Response): A novel clinical endpoint to evaluate therapeutic outcomes in patients with hidradenitis suppurativa from the placebo-controlled portion of a phase 2 adalimumab study. J. Eur. Acad. Dermatol. Venereol., 30: 989-994.
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  13. Karagiannidis, I., T. Kanaki, M. Brunner and C.C. Zouboulis, 2016. Multiple, schwarzliche, brennende Papeln an beiden Fubsohlen einer 20-jahrigen patientin. Der Hautarzt, 67: 586-588.
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  14. Karagiannidis, I., M. Brunner, G. Nikolakis and C.C. Zouboulis, 2016. Zwei anulare, atrophische Plaques am Abdomen bei einem 35-jahrigen patienten. Der Hautarzt, (In Press). 10.1007/s00105-016-3885-0.
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  15. Karagiannidis, I., M. Brunner and C.C. Zouboulis, 2016. Exacerbation of darier disease under interferon-α-2a therapy with clinical signs of a lichen nitidus. Case Rep. Dermatol., 8: 218-223.
  16. Hu, T., Z. Pan, Q. Yu, X. Mo and N. Song et al., 2016. Benzo(a)pyrene induces interleukin (IL)-6 production and reduces lipid synthesis in human SZ95 sebocytes via the aryl hydrocarbon receptor signaling pathway. Environ. Toxicol. Pharmacol., 43: 54-60.
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  17. Hu, T., D. Wang, Q. Yu, L. Li and X. Mo et al., 2016. Aryl hydrocarbon receptor negatively regulates lipid synthesis and involves in cell differentiation of SZ95 sebocytes in vitro. Chem. Biol. Interact., 258: 52-58.
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  18. Hossini, A.M., A.S. Quast, M. Plotz, K. Grauel and T. Exner et al., 2016. PI3K/AKT signaling pathway is essential for survival of induced pluripotent stem cells. PLoS ONE, Vol. 11. 10.1371/journal.pone.0154770.
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  19. Har-Shai, Y. and C.C. Zouboulis, 2016. Intralesional Cryosurgery for the Treatment of Hypertropic Scars and Keloids. In: Dermatological Cryosurgery and Cryotherapy, Abramovits, W., G. Graham, Y. Har-Shai and R. Strumia (Eds.)., Springer, London, pp: 453-474.
  20. Gulliver, W., C.C. Zouboulis, E. Prens, G.B. Jemec and T. Tzellos, 2016. Evidence-based approach to the treatment of hidradenitis suppurativa/acne inversa, based on the European guidelines for hidradenitis suppurativa. Rev. Endocr. Metab. Disord., (In Press). 10.1007/s11154-016-9328-5.
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  21. Giamarellos-Bourboulis, E.J., M. Platzer, I. Karagiannidis, T. Kanni and G. Nikolakis et al., 2016. High copy numbers of beta-defensin cluster on 8p23. 1 confer genetic susceptibility and modulate the physical course of hidradenitis suppurativa/acne inversa. J. Invest. Dermatol., 136: 1592-1598.
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  22. Daxhelet, M., M. Suppa, F. Benhadou, V. Djamei and T. Tzellos et al., 2016. Establishment of a European registry for hidradenitis suppurativa/acne inversa by using an open source software. J. Eur. Acad. Dermatol. Venereol., 30: 1424-1426.
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  23. Dahlhoff, M., T. Frohlich, G.J. Arnold, C.C. Zouboulis and M.R. Schneider, 2016. LC‐MS/MS analysis reveals a broad functional spectrum of proteins in the secretome of sebocytes. Exp. Dermatol., 25: 66-67.
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  24. Dahlhoff, M., C.C. Zouboulis and M.R. Schneider, 2016. Expression of dermcidin in sebocytes supports a role for sebum in the constitutive innate defense of human skin. J. Dermatol. Sci., 81: 124-126.
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  25. Bouloc, A., E. Roo, A. Moga, B. Chadoutaud and C.C. Zouboulis, 2016. A compensating skin care complex containing pro-xylane in menopausal women: Results from a multicentre, evaluator-blinded, randomized study. Acta Derm. Venereol., (In Press). 10.2340/00015555-2572.
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  26. Abdel-Naser, M.B., A.I. Liakou, R. Elewa, S. Hippe, J. Knolle and C.C. Zouboulis, 2016. Increased activity and number of epidermal melanocytes in lesional psoriatic skin. Dermatology, 232: 425-430.
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  27. Zouboulis, C.C., V. del Marmol, U. Mrowietz, E.P. Prens, T. Tzellos and G.B. Jemec, 2015. Hidradenitis suppurativa/acne inversa: Criteria for diagnosis, severity assessment, classification and disease evaluation. Dermatology, 231: 184-190.
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  28. Zouboulis, C.C., E. Jourdan and M. Picardo, 2015. Acne and Lipid Pathways. In: Lipids and Skin Health, Pappas, A. (Ed.)., Springer, Heidelberg, pp: 331-342.
  29. Zouboulis, C.C., 2015. The Brain of the Skin: Sebaceous Gland. In: Lipids and Skin Health, Pappas, A. (Ed.)., Springer, Heidelberg, pp: 109-125.
  30. Zouboulis, C.C., 2015. Adamantiades-Behcet's Disease. In: European Handbook of Dermatological Treatments. 3rd Edn., Katsambas, A.D., T. Lotti, C. Dessinioti and A.M. D'Erme (Eds.)., Springer, Heidelberg, pp: 33-44.
  31. Zampeli, V.A., U. Lippert, G. Nikolakis, E. Makrantonaki, T.G. Tzellos, U. Krause and C.C. Zouboulis, 2015. Disseminated refractory pyoderma gangraenosum during an ulcerative colitis flare. Treatment with infliximab. J. Dermatol. Case Rep., 9: 62-66.
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  32. Tzellos, T., C.C. Zouboulis, W. Gulliver, A.D. Cohen, P. Wolkenstein and G.B.E. Jemec, 2015. Cardiovascular disease risk factors in patients with hidradenitis suppurativa: A systematic review and meta‐analysis of observational studies. Br. J. Dermatol., 173: 1142-1155.
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  33. Saunte, D.M., J. Boer, A. Stratigos, J.C. Szepietowski and I. Hamzavi et al., 2015. Diagnostic delay in hidradenitis suppurativa is a global problem. Br. J. Dermatol., 173: 1546-1549.
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  34. Nikolakis, G., I. Karagiannidis, V.A. Zampeli, A. Altenburg, M. Brunner and C.C. Zouboulis, 2015. Multiple HPV-induced squamous cell carcinomas on the fingers of a patient with systemic lupus erythematosus: A case and review. Case Rep. Dermatol., 7: 329-334.
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  35. Nikolakis, G., H. Seltmann, A.M. Hossini, E. Makrantonaki, J. Knolle and C.C. Zouboulis, 2015. Ex vivo human skin and SZ95 sebocytes exhibit a homoeostatic interaction in a novel coculture contact model. Exp. Dermatol., 24: 497-502.
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  36. Nikolakis, G., E. Makrantonaki and C.C. Zouboulis, 2015. Aging Skin as a Diagnostic Tool for Internal Diseases: A Chance for Dermatology. In: Textbook of Aging Skin, Farage, M.A., K.W. Miller and H.I. Maibach (Eds.). Springer, Berlin, Heidelberg, pp: 1-17.
  37. Mirdamadi, Y., A. Thielitz, A. Wiede, A. Goihl and E. Papakonstantinou et al., 2015. Insulin and insulin-like growth factor-1 can modulate the phosphoinositide-3-kinase/Akt/FoxO1 pathway in SZ95 sebocytes in vitro. Mol. Cell. Endocrinol., 415: 32-44.
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  38. Makrantonaki, E. and C.C. Zouboulis, 2015. Pathomechanisms of Endogenously Aged Skin. In: Textbook of Aging Skin, Farage, M.A., K.W. Miller and H.I. Maibach (Eds.). Springer, Berlin, Heidelberg, pp: 1-10.
  39. Liakou, A.I., A. Pappas and C.C. Zouboulis, 2015. Discovering the Link Between Nutrition and Skin Aging. In: Textbook of Aging Skin, Farage, M.A., K.W. Miller and H.I. Maibach (Eds.). Springer, Berlin, Heidelberg, pp: 1-6.
  40. Lee, S.E., J.M. Kim, S.K. Jeong, E.H. Choi, C.C. Zouboulis and S.H. Lee, 2015. Expression of protease-activated receptor-2 in SZ95 sebocytes and its role in sebaceous lipogenesis, inflammation and innate immunity. J. Invest. Dermatol., 135: 2219-2227.
  41. Kim, S.Y., M.Y. Hyun, K.C. Go, C.C. Zouboulis and B.J. Kim, 2015. Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway. Int. J. Mol. Med., 35: 1042-1050.
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  42. Ikeno, H., M. Apel, C. Zouboulis, T.A. Luger and M. Bohm, 2015. l-Ascorbyl-2-phosphate attenuates NF-κB signaling in SZ95 sebocytes without affecting IL-6 and IL-8 secretion. Arch. Dermatol. Res., 307: 595-605.
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  43. Huang, Y.C., C.H. Yang, T.T. Li, C.C. Zouboulis and H.C. Hsu, 2015. Cell-free extracts of Propionibacterium acnes stimulate cytokine production through activation of p38 MAPK and Toll-like receptor in SZ95 sebocytes. Life Sci., 139: 123-131.
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  44. Hossini, A.M., M. Megges, A. Prigione, B. Lichtner and M.R. Toliat et al., 2015. Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer's disease donor as a model for investigating AD-associated gene regulatory networks. BMC Genomics, Vol. 16. 10.1186/s12864-015-1262-5.
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  45. Farage, M.A., K.W. Miller, C.C. Zouboulis, G.E. Pierard and H.I. Maibach, 2015. Gender Differences in Production and Circulating Level of Sex Hormones and their Impact on Aging Skin. In: Skin, Mucosa and Menopause-Management of Clinical Issues, Farage, M.A., K.W. Miller, N.F. Woods and H.I. Maibach (Eds.). Springer, Berlin, Heidelberg, pp: 125-149.
  46. Elewa, R.M., M.A. Abdallah and C.C. Zouboulis, 2015. Age‐associated skin changes in innate immunity markers reflect a complex interaction between aging mechanisms in the sebaceous gland. J. Dermatol., 42: 467-476.
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  47. El-Haj, N., M. Brunner and C.C. Zouboulis, 2015. Hyperpigmentierte, asymptomatische, anular konfigurierte Plaques mit Satellitenherden. Der Hautarzt, 66: 285-286.
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  48. Dessinioti, C. and C.C. Zouboulis, 2015. Hidradenitis Suppurativa. In: European Handbook of Dermatological Treatments, Katsambas, A.D., T. Lotti, C. Dessinioti and A.M. D'Erme (Eds.). 3rd Edn., Springer, Heidelberg, pp: 411-422.
  49. Dahlhoff, M., T. Frohlich, G.J. Arnold, U. Muller, H. Leonhardt, C.C. Zouboulis and M.R. Schneider, 2015. Characterization of the sebocyte lipid droplet proteome reveals novel potential regulators of sebaceous lipogenesis. Exp. Cell Res., 332: 146-155.
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  50. Dahlhoff, M., E. Camera, M. Ludovici, M. Picardo and U. Muller et al., 2015. EGFR/ERBB receptors differentially modulate sebaceous lipogenesis. FEBS Lett., 589: 1376-1382.
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  51. Zouboulis, C.C., U. Lippert and I. Karagiannidis, 2014. Multi-organ sarcoidosis treatment with fumaric acid esters: A case report and review of the literature. Dermatology, 228: 202-206.
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  52. Zouboulis, C.C., G. Nikolakis and C. Dessinioti, 2014. Molecular Aspects of Sebaceous Differentiation. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, Heidelberg, pp: 19-26.
  53. Zouboulis, C.C., C. Dessinioti and C. Antoniou, 2014. Acne Epidemiology and Socioeconomic Aspects. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 53-57.
  54. Zouboulis, C.C., A. Katsambas and A.M. Kligman, 2014. Preface-The History of this Book. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: vii-ix.
  55. Zouboulis, C.C., A. Achenbach and E. Makrantonaki, 2014. Acne tarda and male-pattern baldness unmasking primary ovarian insufficiency: A case and review. Dermatology, 229: 51-54.
  56. Zouboulis, C.C., 2014. Acne and Antimicrobial Lipids. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 179-183.
  57. Zouboulis, C.C. and H.P.M. Gollnick, 2014. Understanding Acne as a Chronic Disease. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 209-211.
  58. Zouboulis, C.C. and F. Tsatsou, 2014. Anatomy of the Sebaceous Gland. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, Heidelberg, pp: 27-31.
  59. Zouboulis, C.C. and E. Makrantonaki, 2014. The Role of the Sebaceous Gland. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 77-90.
  60. Zouboulis, C.C. and C. Dessinioti, 2014. The SAHA Syndrome. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 563-567.
  61. Zouboulis, C.C. and C. Dessinioti, 2014. Experimental Models of the Sebaceous Gland. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, New York, pp: 43-49.
  62. Zouboulis, C.C. and C. Dessinioti, 2014. Acne and Inflammation. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 135-141.
  63. Zouboulis, C.C. and C. Dessinioti, 2014. A New Concept of Acne Pathogenesis. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 105-107.
  64. Zouboulis, C.C. and A.I. Liakou, 2014. Evidenced-Based Treatment of Acne. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 379-382.
  65. Zhang, S., G. Shui, G. Wang, C. Wang and S. Sun et al., 2014. Cidea control of lipid storage and secretion in mouse and human sebaceous glands. Mol. Cell. Biol., 34: 1827-1838.
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  66. Tsatsou, F. and C.C. Zouboulis, 2014. Acne Vulgaris. In: Treatment of Skin Disease: Comprehensive Therapeutic Strategies, Lebwohl, M.G., W.R. Heymann, J. Berth-Jones and I. Coulson (Eds.). 4th Edn., Elsevier Saunders, New York, pp: 6-11.
  67. Torocsik, D., D. Kovacs, E. Camera, M. Lovaszi and K. Cseri et al., 2014. Leptin promotes a proinflammatory lipid profile and induces inflammatory pathways in human SZ95 sebocytes. Br. J. Dermatol., 171: 1326-1335.
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  68. Theodoridis, A., A. Konstantinidou, E. Makrantonaki and C.C. Zouboulis, 2014. Malignant and benign forms of atrophic papulosis (Kohlmeier-Degos disease): Systemic involvement determines the prognosis. Br. J. Dermatol., 170: 110-115.
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  69. Piret, J.P., J. Mejia, S. Lucas, C.C. Zouboulis, C. Saout and O. Toussaint, 2014. Sonicated and stirred copper oxide nanoparticles induce similar toxicity and pro-inflammatory response in N-hTERT keratinocytes and SZ95 sebocytes. J. Nanoparticle Res., Vol. 16. 10.1007/s11051-014-2337-y.
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  70. Olah, A., B.I. Toth, I. Borbiro, K. Sugawara and A.G. Szollosi et al., 2014. Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes. J. Clin. Invest., 124: 3713-3724.
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  71. Li, Z.J., D.K. Choi, K.C. Sohn, M.S. Seo and H.E. Lee et al., 2014. Propionibacterium acnes activates the NLRP3 inflammasome in human sebocytes. J. Invest. Dermatol., 134: 2747-2756.
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  72. Knobler, R., G. Berlin, P. Calzavara‐Pinton, H. Greinix and P. Jaksch et al., 2014. Guidelines on the use of extracorporeal photopheresis. J. Eur. Acad. Dermatol. Venereol., 28: 1-37.
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  73. Kligman, A.M. and C.C. Zouboulis, 2014. Rosacea: The State of the Art. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 605-609.
  74. Katsambas, A.D., W.J. Cunliffe and C.C. Zouboulis, 2014. Clinical Aspects of Acne Vulgaris. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 213-221.
  75. Inoue, T., Y. Miki, S. Kakuo, A. Hachiya and T. Kitahara et al., 2014. Expression of steroidogenic enzymes in human sebaceous glands. J. Endocrinol., 222: 301-312.
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  76. Huang, W.C., T.H. Tsai, L.T. Chuang, Y.Y. Li, C.C. Zouboulis and P.J. Tsai, 2014. Anti-bacterial and anti-inflammatory properties of capric acid against Propionibacterium acnes: A comparative study with lauric acid. J. Dermatol. Sci., 73: 232-240.
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  77. Hu, T., Q. Yu, X. Mo, N. Song, M. Yan, L. Xia, C.C. Zouboulis and Q. Ju, 2014. In vitro effects of nicotine on the proliferation, apoptosis and lipid synthesis of immortalized human SZ95 sebocytes. Chin. J. Derm. Venereol., 28: 1-5.
  78. Fimmel, S., H. Kutzner and C.C. Zouboulis, 2014. The Vascular Concept. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 611-619.
  79. Dozsa, A., B. Dezso, B.I. Toth, A. Bacsi and S. Poliska et al., 2014. PPARγ nuclear receptor coupled arachidonic acid signaling is involved in differentiation and lipid production of human sebocytes. J. Invest. Dermatol., 134: 910-920.
  80. Dessinioti, C. and C.C. Zouboulis, 2014. Laboratory Evaluation in Acne. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 369-375.
  81. Dessinioti, C. and C.C. Zouboulis, 2014. Hormonal Therapy for Acne. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 477-482.
  82. Dessinioti, C. and C.C. Zouboulis, 2014. Concepts of Future Acne Treatment. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 537-542.
  83. Dessinioti, C. and C.C. Zouboulis, 2014. Body Mass Index. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 295-297.
  84. Davatchi, F., S. Assaad‐Khalil, K.T. Calamia, J.E. Crook and B. Sadeghi‐Abdollahi et al., 2014. The international criteria for Behcet's disease (ICBD): A collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J. Eur. Acad. Dermatol. Venereol., 28: 338-347.
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  85. Dahlhoff, M., E. Camera, M. Picardo, C.C. Zouboulis and M.R. Schneider, 2014. Angiopoietin-like 4, a protein strongly induced during sebocyte differentiation, regulates sebaceous lipogenesis but is dispensable for sebaceous gland function in vivo. J. Dermatol. Sci., 75: 148-150.
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  86. Crowley, J.J., J.R. Mekkes, C.C. Zouboulis, N. Scheinfeld and A. Kimball et al., 2014. Association of hidradenitis suppurativa disease severity with increased risk for systemic comorbidities. Br. J. Dermatol., 171: 1561-1565.
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  87. Chen, W., C.C. Yang and C.C. Zouboulis, 2014. The Acne Genes. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 349-354.
  88. Chen, W. and C.C. Zouboulis, 2014. Serum Androgens. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 291-294.
  89. Chen, W. and C.C. Zouboulis, 2014. Acne and Androgens. In: Pathogenesis and Treatment of Acne and Rosacea, Zouboulis, C.C., A.D. Katsambas and A.M. Kligman (Eds.). Springer, Berlin, pp: 131-134.
  90. Camera, E., M. Dahlhoff, M. Ludovici, C.C. Zouboulis and M.R. Schneider, 2014. Perilipin 3 modulates specific lipogenic pathways in SZ95 sebocytes. Exp. Dermatol., 23: 759-761.
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  91. Bonitsis, N.G., L.B.L. Nguyen, M.P. LaValley, N. Papoutsis and A. Altenburg et al., 2014. Gender-specific differences in Adamantiades-Behcet's disease manifestations: An analysis of the German registry and meta-analysis of data from the literature. Rheumatology, 54: 121-133.
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  93. Yu, Q., T. Hu, X. Mo, C. Zhang, L. Xia, C.C. Zouboulis and Q. Ju, 2013. Effect of tetrachlorodibenzo-p-dioxin on the expression of cytochrome P4501A1 in human SZ95 sebocytes and its significance. J. Environ. Health, 30: 126-129.
  94. Yu, Q., T. Hu, X. Mo, C. Zhang, L. Xia, C.C. Zouboulis and Q. Ju, 2013. Effect of tetrachlorodibenzo-p-dioxin on the expression of cytochrome P4501A1 in human SZ95 sebocytes and its significance. Chin. J. Dermatol., 46: 557-560.
  95. Tzellos, T., A. Kyrgidis and C.C. Zouboulis, 2013. Re‐evaluation of the risk for major adverse cardiovascular events in patients treated with anti‐IL‐12/23 biological agents for chronic plaque psoriasis: A meta‐analysis of randomized controlled trials. J. Eur. Acad. Dermatol. Venereol., 27: 622-627.
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  97. Schneider, M.R., A. Samborski, S. Bauersachs and C.C. Zouboulis, 2013. Differentially regulated microRNAs during human sebaceous lipogenesis. J. Dermatol. Sci., 70: 88-93.
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  98. Lee, S.E., J.M. Kim, M.K. Jeong, C.C. Zouboulis and S.H. Lee, 2013. 11β-hydroxysteroid dehydrogenase type 1 is expressed in human sebaceous glands and regulates glucocorticoid-induced lipid synthesis and toll‐like receptor 2 expression in SZ95 sebocytes. Br. J. Dermatol., 168: 47-55.
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  99. Kakanj, P., K. Reuter, G. Sequaris, C. Wodtke and P. Schettina et al., 2013. Indian hedgehog controls proliferation and differentiation in skin tumorigenesis and protects against malignant progression. Cell Rep., 4: 340-351.
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  100. Hampel, U., T. Klonisch, S. Sel, U. Schulze and F. Garreis et al., 2013. Insulin-like factor 3 promotes wound healing at the ocular surface. Endocrinology, 154: 2034-2045.
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  101. Dahlhoff, M., E. Camera, M. Picardo, C.C. Zouboulis, L. Chan, B. Chang and M.R. Schneider, 2013. PLIN2, the major perilipin regulated during sebocyte differentiation, controls sebaceous lipid accumulation in vitro and sebaceous gland size in vivo. Biochim. Biophys. Acta Gen. Subjects, 1830: 4642-4649.
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  102. Zouboulis, C.C., 2012. Adamantiades-Behcet Disease. In: Fitzpatrick's Dermatology in General Medicine, Goldsmith, L.A., S.I. Katz, B.A. Gilchrest, A.S. Paller, D.J. Leffell and K. Wolff (Eds.). 8th Edn., McGraw Hill, New York, pp: 2033-2042.
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  105. Vankoningsloo, S., J.P. Piret, C. Saout, F. Noel and J. Mejia et al., 2012. Pro-inflammatory effects of different MWCNTs dispersions in p16INK4A-deficient telomerase-expressing human keratinocytes but not in human SV-40 immortalized sebocytes. Nanotoxicology, 6: 77-93.
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  106. Takata, T., M. Tarutani, C.C. Zouboulis and S. Sano, 2012. Sebaceous glands as the primary target of EGFR-inhibitors in the development of papulopustular eruption. J. Dermatol. Sci., 66: 165-168.
  107. Piret, J.P., S. Vankoningsloo, J. Mejia, F. Noel and E. Boilan et al., 2012. Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal Caco-2 cell monolayers is correlated in part to copper release and shape. Nanotoxicology, 6: 789-803.
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  109. Nakahigashi, K., H. Doi, A. Otsuka, T. Hirabayashi and M. Murakami et al., 2012. PGD2 induces eotaxin-3 via PPARγ from sebocytes: A possible pathogenesis of eosinophilic pustular folliculitis. J. Allergy Clin. Immunol., 129: 536-543.
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  110. Moubasher, A.A., U. Lippert and C.C. Zouboulis, 2012. Development of an epithelial tumour on the scar of a surgically excised mesenchymal tumour. Egypt. Dermatol., Vol. 8. .
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  111. Makrantonaki, E., T.C. Brink, V. Zampeli, R.M. Elewa and B. Mlody et al., 2012. Identification of biomarkers of human skin ageing in both genders. Wnt Signalling-a label of skin ageing? PLoS One, Vol. 7. 10.1371/journal.pone.0050393.
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  114. Jahns, A.C., B. Lundskog, R. Ganceviciene, R.H. Palmer and I. Golovleva et al., 2012. An increased incidence of Propionibacterium acnes biofilms in acne vulgaris: A case control study. Br. J. Dermatol., 167: 50-58.
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  118. Elewa, R.M., M. Abdallah, N. Youssef and C.C. Zouboulis, 2012. Aging-related changes in cutaneous corticotropin-releasing hormone system reflect a defective neuroendocrine-stress response in aging. Rejuvenation Res., 15: 366-373.
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  119. Choi, J.J., M.Y. Park, H.J. Lee, D.Y. Yoon and Y. Lim et al., 2012. TNF-α increases lipogenesis via JNK and PI3K/Akt pathways in SZ95 human sebocytes. J. Dermatol. Sci., 65: 179-188.
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  122. Zouboulis, C.C., S. Angres and H. Seltmann, 2011. Regulation of stearoyl-coenzyme a desaturase and fatty acid delta-6 desaturase-2 expression by linoleic acid and arachidonic acid in human sebocytes leads to enhancement of proinflammatory activity but does not affect lipogenesis. Br. J. Dermatol., 165: 269-276.
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  124. Vankoningsloo, S., J.P. Piret, C. Saout, F. Noel and J. Mejia et al., 2011. Cytotoxicity of multi-walled carbon nanotubes in three skin cellular models: Effects of sonication, dispersive agents and corneous layer of reconstructed epidermis. Nanotoxicology, 4: 84-97.
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  128. Liakou, A.I., M.J. Theodorakis and C.C. Zouboulis, 2011. Nutritional Clinical Studies in Dermatology. In: Nutrition and Skin: Lessons for Anti-Aging, Beauty and Healthy Skin, Pappas, A. (Ed.). Springer, New York, pp: 209-220.
  129. Liakou, A.I., M. Brunner, M.J. Theodorakis, E. Makrantonaki and C.C. Zouboulis, 2011. Recurrent subacute cutaneous lupus erythematosus following exposure to different drugs. Acta Dermato Venereol., 91: 586-587.
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  130. Ju, Q., S. Fimmel, N. Hinz, R. Stahlmann, L. Xia and C.C. Zouboulis, 2011. 2,3,7,8-tetrachlorodibenzo-p-dioxin alters sebaceous gland cell differentiation in vitro. Exp. Dermatol., 20: 320-325.
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  131. Ju, Q., Q. Yu, N. Song, Y. Tan, L. Xia and C.C. Zouboulis, 2011. Expression of aryl hydrocarbon receptor in human epidermis, hair follicles and sebaceous glands and its significance. Chin. J. Dermatol., 44: 761-764, (In Chinese).
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  133. Elewa, R., A. Altenburg and C.C. Zouboulis, 2011. Recalcitrant severe erosive cutaneous lichen planus treated with extracorporeal photopheresis monotherapy. Br. J. Dermatol., 165: 441-443.
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  134. Chen, C.H., Y. Wang, T. Nakatsuji, Y.T. Liu and C.C. Zouboulis et al., 2011. An innate bactericidal oleic acid effective against skin infection of methicillin-resistant staphylococcus aureus: A therapy concordant with evolutionary medicine. J. Microbiol. Biotechnol., 21: 391-399.
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  136. Zouboulis, C.C., H. Seltmann and T. Alestas, 2010. Zileuton prevents the activation of the leukotriene pathway and reduces sebaceous lipogenesis. Exp. Dermatol., 19: 148-150.
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  137. Zouboulis, C.C. and M.B. Abdel Naser, 2010. Acne and Its Variants. In: Treatment of Skin Diseases, Krieg, T., D. Bickers and Y. Miyachi (Eds.). Springer, Berlin, Heidelberg, pp: 359-373.
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  144. Makrantonaki, E. and C.C. Zouboulis, 2010. Pathomechanisms of Endogenously Aged Skin. In: Textbook of Aging Skin, Farage, M.A., K.W. Miller and H.I. Maibach (Eds.). Springer, Berlin, Heidelberg, pp: 94-99.
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  148. Ikuta, T., M. Ohba, C.C. Zouboulis, Y. Fujii-Kuriyama and K. Kawajiri, 2010. B lymphocyte-induced maturation protein 1 is a novel target gene of aryl hydrocarbon receptor. J. Dermatol. Sci., 58: 211-216.
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  151. Chen, W., S.J. Tsai, H.M. Sheu, J.C. Tsai and C.C. Zouboulis, 2010. Testosterone synthesized in cultured human SZ95 sebocytes derives mainly from dehydroepiandrosterone. Exp. Dermatol., 19: 470-472.
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  152. Capitanio, B., J.L. Sinagra, V. Bordignon, P.C. Fei, M. Picardo and C.C. Zouboulis, 2010. Underestimated clinical features of postadolescent acne. J. Am. Acad. Dermatol., 63: 782-788.
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  153. Abdel-Naser, M.B. and C.C. Zouboulis, 2010. Rosacea and Related Disorders. In: Treatment of Skin Diseases, Krieg, T., D. Bickers and Y. Miyachi (Eds.). Springer, Berlin, Heidelberg, pp: 375-386.
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  166. Krause, L., A.K. Kohler, A. Altenburg, N. Papoutsis and C.C. Zouboulis et al., 2009. Ocular involvement in Adamantiades-Behcet's disease in Berlin, Germany. Graefe's Arch. Clin. Exp. Ophthalmol., 247: 661-666.
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  167. Kramer, C., H. Seltmann, M. Seifert, W. Tilgen, C.C. Zouboulis and J. Reichrath, 2009. Characterization of the vitamin D endocrine system in human sebocytes in vitro. J. Steroid Biochem. Mol. Biol., 113: 9-16.
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  168. Hoxha, F.T., S. Hashani, A. Krasniqi, M. Pllana and D. Komoni et al., 2009. Intestinal vasculitis in Adamantiades-Behcet disease presenting as acute abdomen. J. Eur. Acad. Dermatol. Venereol., 23: 1461-1463.
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  169. Ghodsi, S.Z., H. Orawa and C.C. Zouboulis, 2009. Prevalence, severity and severity risk factors of acne in high school pupils: A community-based study. J. Invest. Dermatol., 129: 2136-2141.
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  170. Ganceviciene, R., V. Graziene, S. Fimmel and C.C. Zouboulis, 2009. Involvement of the corticotropin-releasing hormone system in the pathogenesis of acne vulgaris. Br. J. Dermatol., 160: 345-352.
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  171. Efentaki, P., A. Altenburg, J. Haerting and C.C. Zouboulis, 2009. Medium-dose prednisolone pulse therapy in alopecia areata. Dermato-Endocrinology, 1: 311-314.
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  172. Chen, W., S.J. Tsai, C.A. Wang, J.C. Tsai and C.C. Zouboulis, 2009. Human sebocytes express prostaglandin E2 receptors EP2 and EP4 but treatment with prostaglandin E2 does not affect testosterone production. Br. J. Dermatol., 161: 674-677.
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  173. Brunner, M. and C.C. Zouboulis, 2009. Purpura Schoenlein-Henoch. In: Encyclopedia of Molecular Mechanisms of Disease, Lang, F. (Ed.). Springer, Berlin, Heidelberg, ISBN: 9783540671367, pp: 1787-1788.
  174. Zouboulis, C.C., 2008. Adamantiades-Behcet Disease. In: Fitzpatrick's Dermatology in General Medicine, Volume 2, Fitzpatrick, T.B. and K. Wolff (Eds.). 7th Edn., McGraw Hill, New York, ISBN: 9780071494434, pp: 1620-1626.
  175. Storz, K., J. Loffler, S. Koch, R. Vonthein and C.C. Zouboulis et al., 2008. IL-6 receptor, IL-8 receptor and TNF-α238 (G/A) polymorphisms are not associated with Behcet's disease in patients of German or Turkish origin. Clin. Exp. Rheumatol., 26: S103-S106.
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  176. Rozner, S., L. Verkhovski, Y. Nissimov, A. Aserin and R. Vilensky et al., 2008. Inhibition of cholesterol transport into skin cells in cultures by phytosterol-loaded microemulsion. Chem. Phys. Lipids, 153: 109-118.
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  177. Pelle, E., J. McCarthy, H. Seltmann, X. Huang, T. Mammone, C.C. Zouboulis and D. Maes, 2008. Identification of histamine receptors and reduction of squalene levels by an antihistamine in sebocytes. J. Invest. Dermatol., 128: 1280-1285.
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  178. Nakatsuji, T., Y.T. Liu, C.P. Huang, R.L. Gallo and C.M. Huang, 2008. Antibodies elicited by inactivated Propionibacterium acnes-based vaccines exert protective immunity and attenuate the IL-8 production in human sebocytes: Relevance to therapy for acne vulgaris. J. Invest. Dermatol., 128: 2451-2457.
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  179. Nakatsuji, T., Y. Shi, W. Zhu, C.P. Huang and Y.R. Chen et al., 2008. Bioengineering a humanized acne microenvironment model: Proteomics analysis of host responses to Propionibacterium acnes infection in vivo. Proteomics, 8: 3406-3415.
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  180. Makrantonaki, E., K. Vogel, S. Fimmel, M. Oeff, H. Seltmann and C.C. Zouboulis, 2008. Interplay of IGF-I and 17β-estradiol at age-specific levels in human sebocytes and fibroblasts in vitro. Exp. Gerontol., 43: 939-946.
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  181. Lo Celso, C., M.A. Berta, K.M. Braun, M. Frye, S. Lyle, C.C. Zouboulis and F.M. Watt, 2008. Characterization of bipotential epidermal progenitors derived from human sebaceous gland: Contrasting roles of c-Myc and β-catenin. Stem Cells, 26: 1241-1252.
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  182. Lee, D.Y., K. Yamasaki, J. Rudsil, C.C. Zouboulis, G.T. Park, J.M. Yang and R.L. Gallo, 2008. Sebocytes express functional cathelicidin antimicrobial peptides and can act to kill propionibacterium acnes. J. Invest. Dermatol., 128: 1863-1866.
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  183. Krause, L., A. Altenburg, U. Pleyer, A.K. Kohler, C.C. Zouboulis and M.H. Foerster, 2008. Longterm visual prognosis of patients with ocular Adamantiades-Behcet's disease treated with interferon-alpha-2a. J. Rheumatol., 35: 896-903.
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  184. Kiss, B., T. Biro, G. Czifra, B.I. Toth and Z. Kertesz et al., 2008. Investigation of micronized titanium dioxide penetration in human skin xenografts and its effect on cellular functions of human skin-derived cells. Exp. Dermatol., 17: 659-667.
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  185. Hong, I., M.H. Lee, T.Y. Na, C.C. Zouboulis and M.O. Lee, 2008. LXRα enhances lipid synthesis in SZ95 sebocytes. J. Invest. Dermatol., 128: 1266-1272.
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  186. Dobrosi, N., B.I. Toth, A. Dozsa, T. Geczy and G. Nagy et al., 2008. Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling. FASEB J., 22: 3685-3695.
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  187. Willerding, G., H. Heimann, C.C. Zouboulis and L. Krause, 2007. Acute central retinal artery occlusion in Adamantiades-Behcet disease. Eye, 21: 1006-1007.
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  188. Voegeli, R., P. Elsner, C.C. Zouboulis and T. Schreier, 2007. 5α-Reductase and its Inhibitors for the Treatment of Acne. In: Acne and its Therapy, Webster, G.F. and A.V. Rawlings (Eds.). CRC Press, New York, ISBN: 9781420018417, pp: 167-201.
  189. Thielitz, A., D. Reinhold, R. Vetter, U. Bank and M. Helmuth et al., 2007. Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation. J. Invest. Dermatol., 127: 1042-1051.
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  190. Steinhoff, M., H. Rochlitz, G. Nussbaum, J. Georgieva and C.C. Zouboulis, 2007. Reduced growth of beard as the only diagnostic sign in a patient with macroprolactinoma. J. Eur. Acad. Dermatol. Venereol., 21: 124-126.
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  191. Seiffert, K., H. Seltmann, M. Fritsch and C.C. Zouboulis, 2007. Inhibition of 5α-reductase activity in SZ95 sebocytes and HaCaT keratinocytes in vitro. Hormone Metab. Res., 39: 141-148.
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  192. Schroeder, M. and C.C. Zouboulis, 2007. All-trans-retinoic acid and 13-cis-retinoic acid: Pharmacokinetics and biological activity in different cell culture models of human keratinocytes. Hormone Metab. Res., 39: 136-140.
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  193. Russell, L.E., W.J. Harrison, A.W. Bahta, C.C. Zouboulis, J.M. Burrin and M.P. Philpott, 2007. Characterization of liver X receptor expression and function in human skin and the pilosebaceous unit. Exp. Dermatol., 16: 844-852.
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  194. Makrantonaki, E. and C.C. Zouboulis, 2007. The skin as a mirror of the aging process in the human organism-state of the art and results of the aging research in the German National Genome Research Network 2 (NGFN-2). Exp. Gerontol., 42: 879-886.
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  195. Makrantonaki, E. and C.C. Zouboulis, 2007. Testosterone metabolism to 5α-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytes. Br. J. Dermatol., 156: 428-432.
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  196. Krause, L., A. Altenburg, N.E. Bechrakis, G. Willerding, C.C. Zouboulis and M.H. Foerster, 2007. Intraocular surgery under systemic interferon-alpha therapy in ocular Adamantiades-Behcet's disease. Graefe's Arch. Clin. Exp. Ophthalmol., 245: 1617-1621.
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  197. Krause, K., A. Schnitger, S. Fimmel, E. Glass and C.C. Zouboulis, 2007. Corticotropin-releasing hormone skin signaling is receptor-mediated and is predominant in the sebaceous glands. Hormone Metab. Res., 39: 166-170.
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  198. Kalayciyan, A., H. Orawa, S. Fimmel, F.H. Perschel and J.B. Gonzalez et al., 2007. Nicotine and biochanin A, but not cigarette smoke, induce anti-inflammatory effects on keratinocytes and endothelial cells in patients with Behcet's disease. J. Invest. Dermatol., 127: 81-89.
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  199. Harrison, W.J., J.J. Bull, H. Seltmann, C.C. Zouboulis and M.P. Philpott, 2007. Expression of lipogenic factors galectin-12, resistin, SREBP-1 and SCD in human sebaceous glands and cultured sebocytes. J. Invest. Dermatol., 127: 1309-1317.
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  200. Har‐Shai, Y., E. Dujovny, E. Rohde and C.C. Zouboulis, 2007. Effect of skin surface temperature on skin pigmentation during contact and intralesional cryosurgery of keloids. J. Eur. Acad. Dermatol. Venereol., 21: 191-198.
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  201. Ganceviciene, R., V. Graziene, M. Bohm and C.C. Zouboulis, 2007. Increased in situ expression of melanocortin-1 receptor in sebaceous glands of lesional skin of patients with acne vulgaris. Exp. Dermatol., 16: 547-552.
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  202. Fimmel, S., R. Kurfurst, F. Bonte and C.C. Zouboulis, 2007. Responsiveness to androgens and effectiveness of antisense oligonucleotides against the androgen receptor on human epidermal keratinocytes is dependent on the age of the donor and the location of cell origin. Horm. Metab. Res., 39: 157-165.
  203. Fimmel, S., L. Devermann, A. Herrmann and C. Zouboulis, 2007. GRO‐α: A potential marker for cancer and aging silenced by RNA interface. Ann. N. Y. Acad. Sci., 1119: 176-189.
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  204. Fimmel, S., A. Saborowski, B. Terouanne, C. Sultan and C.C. Zouboulis, 2007. Inhibition of the androgen receptor by antisense oligonucleotides regulates the biological activity of androgens in SZ95 sebocytes. Horm. Metab. Res., 39: 149-156.
  205. Chen, W., C.C. Yang, R.Y. Tsai, C.Y. Liao and Y.T. Yen et al., 2007. Expression of sex-determining genes in the scalp of men with androgenetic alopecia. Dermatology, 214: 199-204.
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  206. Atecova, J., W. Mehnert, T. Blaschke, B. Kleuser and R. Sivaramakrishnan et al., 2007. Cyproterone acetate loading to lipid nanoparticles for topical acne treatment: Particle characterisation and skin uptake. Pharmaceut. Res., 24: 991-1000.
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  207. Zouboulis, C.C. and E. Makrantonaki, 2006. The Role of Hormones in Intrinsic Aging. In: Skin Aging, Gilchrest, B. and J. Krutmann (Eds.). Springer, New York, pp: 55-64.
  208. Zouboulis, C.C. and C.A. Stratakis, 2006. Laminin α1-chain may have a role in adnexal morphogenesis. Dermatology, 213: 175-176.
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  209. Zhang, Q., H. Seltmann, C.C. Zouboulis and R.L. Konger, 2006. Involvement of PPARγ in oxidative stress-mediated prostaglandin E2 production in SZ95 human sebaceous gland cells. J. Invest. Dermatol., 126: 42-48.
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  210. Zhang, Q., H. Seltmann, C.C. Zouboulis and J.B. Travers, 2006. Activation of platelet‐activating factor receptor in SZ95 sebocytes results in inflammatory cytokine and prostaglandin E2 production. Exp. Dermatol., 15: 769-774.
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  211. Winiarska, A., N. Mandt, H. Kamp, A. Hossini, H. Seltmann, C.C. Zouboulis and U. Blume-Peytavi, 2006. Effect of 5α-dihydrotestosterone and testosterone on apoptosis in human dermal papilla cells. Skin Pharmacol. Physiol., 19: 311-321.
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  212. Toussaint, O., B. Rayet, F. Chainiaux, C.C. Zouboulis, G. Butler-Browne, C. Chen and T.B. Kirkwood, 2006. LINK-AGE: Coordination and consolidation of European biogerontology: En route towards formation of a European college of biogerontology. Mech. Ageing Dev., 127: 761-762.
  213. Thielitz, A., D. Reinhold, R. Vetter, U. Lendeckel and T. Kahne et al., 2006. Possible role of DP IV inhibitors in acne therapy. Adv. Exp. Med. Biol., 575: 163-167.
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  214. Takeda, H., S. Lyle, A.J. Lazar, C.C. Zouboulis, I. Smyth and F.M. Watt, 2006. Human sebaceous tumors harbor inactivating mutations in LEF1. Nat. Med., 12: 395-397.
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  215. Selleri, S., H. Seltmann, S. Gariboldi, Y.F. Shirai, A. Balsari, C.C. Zouboulis and C. Rumio, 2006. Doxorubicin-induced alopecia is associated with sebaceous gland degeneration. J. Invest. Dermatol., 126: 711-720.
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  216. Papoutsis, N.G., M.B. Abdel-Naser, A. Altenburg, H. Orawa and I. Kotter et al., 2006. Prevalence of Adamantiades-Behcet's disease in Germany and the municipality of Berlin: Results of a nationwide survey. Clin. Exp. Rheumatol., 24: S215-S215.
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  217. Ottaviani, M., T. Alestas, E. Flori, A. Mastrofrancesco, C.C. Zouboulis and M. Picardo, 2006. Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: A possible role in acne vulgaris. J. Invest. Dermatol., 126: 2430-2437.
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  218. Oeff, M.K., H. Seltmann, N. Hiroi, A. Nastos, E. Makrantonaki, S.R. Bornstein and C.C. Zouboulis, 2006. Differential regulation of Toll-like receptor and CD14 pathways by retinoids and corticosteroids in human sebocytes. Dermatology, 213: 266-266.
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  219. Nagy, I., A. Pivarcsi, K. Kis, A. Koreck and L. Bodai et al., 2006. Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human sebocytes. Microb. Infect., 8: 2195-2205.
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  220. Morita, K., C.L. Celso, B. Spencer-Dene, C.C. Zouboulis and F.M. Watt, 2006. HAN11 binds mDia1 and controls Gli1 transcriptional activity. J. Dermatol. Sci., 44: 11-20.
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  221. Makrantonaki, E., J. Adjaye, R. Herwig, T.C. Brink and D. Groth et al., 2006. Aging of human sebocytes in vitro induced by exposure to a defined hormone environment. Dermatology, 213: 262-263.
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  222. Makrantonaki, E., J. Adjaye, R. Herwig, T.C. Brink and D. Groth et al., 2006. Age‐specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro. Aging Cell, 5: 331-344.
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  223. Kosaka, S., S. Kawana, C.C. Zouboulis, T. Hasan and B. Ortel, 2006. Targeting of sebocytes by aminolevulinic acid-dependent photosensitization. Photochem. Photobiol., 82: 453-457.
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  224. Har‐Shai, Y., E. Sabo, E. Rohde, M. Hyams, C. Assaf and C.C. Zouboulis, 2006. Intralesional cryosurgery enhances the involution of recalcitrant auricular keloids: A new clinical approach supported by experimental studies. Wound Repair Regenerat., 14: 18-27.
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  225. Grone, D., R. Treudler, E.M. de Villiers, R. Husak, C.E. Orfanos and C.C. Zouboulis, 2006. Intravenous cidofovir treatment for recalcitrant warts in the setting of a patient with myelodysplastic syndrome. J. Eur. Acad. Dermatol., 20: 202-205.
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  226. Ganceviciene, R., S. Fimmel, E. Glass and C.C. Zouboulis, 2006. Psoriasin and follicular hyperkeratinization in acne comedones. Dermatology, 213: 270-272.
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  227. Ganceviciene, R., I. Marciukaitiene, V. Graziene, A. Rimkevicius and C.C. Zouboulis, 2006. New accents in the pathogenesis of acne vulgaris. Acta Medica Lituanica, 13: 83-87.
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  228. Chen, W., S.J. Tsai, C.Y. Liao, R.Y. Tsai and Y.J. Chen et al., 2006. Higher levels of steroidogenic acute regulatory protein and type I 3β-hydroxysteroid dehydrogenase in the scalp of men with androgenetic alopecia. J. Invest. Dermatol., 126: 2332-2335.
  229. Chen, W., C.Y. Liao, C.L. Hung, T.K. Lin, H.M. Sheu and C.C. Zouboulis, 2006. Potent corticosteroids inhibit lipogenesis in sebaceous glands. Dermatology, 213: 264-265.
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  230. Chen, W., C.C. Yang, C.Y. Liao, C.L. Hung and S.J. Tsai et al., 2006. Expression of sex‐determining genes in human sebaceous glands and their possible role in the pathogenesis of acne. J. Eur. Acad. Dermatol. Venereol., 20: 846-852.
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  231. Altenburg, A., N. Papoutsis, H. Orawa, P. Martus and C.C. Zouboulis, 2006. Epidemiologie und klinik des morbus adamantiades-behcet in deutschland-aktuelle pathogenetische konzepte und therapeutische moglichkeiten. J. Dtsch. Dermatol. Ges., 4: 49-66.
  232. Alestas, T., R. Ganceviciene, S. Fimmel, K. Muller-Decker and C.C. Zouboulis, 2006. Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands. J. Mol. Med., 84: 75-87.
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  233. Zouboulis, C.C., A. Saborowski and A. Boschnakow, 2005. Zileuton, an oral 5-lipoxygenase inhibitor, directly reduces sebum production. Dermatology, 210: 36-38.
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  234. Zouboulis, C.C. and H. Rohrs, 2005. Kryochirurgische behandlung aktinischer keratosen mit evidenzbasierter ubersicht. Der Hautarzt, 56: 353-358.
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  235. Treudler, R. and C.C. Zouboulis, 2005. Follicular drug eruption induced by gefitinib (ZD 1839, Iressa): Clinical picture correlates with in vitro data of focal epidermal necrosis after epidermal growth factor inhibition in skin cultures. Dermatology, 211: 375-376.
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  236. Tchernev, G., M. Steinhoff, I. Sheitanov, C.C. Zouboulis and C. Orfanos, 2005. [Scleredema adultorum buschke with monoclonal gammopathy, diabetes mellitus type II and initial disturbances in esophageal motility]. Rheumatologia, 13: 38-41, (In Bulgarian).
  237. Tchernev, G., D. Trebing, H.D. Goring, M. Steinhoff, C.C. Zouboulis and C. Orfanos, 2005. [Pyoderma gangrenosum in Crohn's disease-the role of immunologic parameters and histological data in diagnosis and differential diagnosis]. Bulg. J. Hepatogastroenterol., 7: 56-60, (In Bulgarian).
  238. Tchernev, G., C. Geilen, C.C. Zouboulis and C. Orfanos, 2005. [p53-Role in regulation of cell cycle and apoptosis in carcinomas and malignant melanoma]. Curr. Med., 36: 47-54, (In Bulgarian).
  239. Tchernev, G., C. Geilen, C.C. Zouboulis and C. Orfanos, 2005. [Malignant melanoma-role of cell modulators p16, p21, p27 and tumor suppressing protein Rb as new prognostic factors]. Curr. Med., 36: 41-46, (In Bulgarian).
  240. Seiffert, K., E. Hilbert, H. Schaechinger, C.C. Zouboulis and H.C. Deter, 2005. Psychophysiological reactivity under mental stress in atopic dermatitis. Dermatology, 210: 286-293.
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  241. Preib, J.C., C.C. Zouboulis, M. Zeitz and R. Duchmann, 2005. Schwere psoriatische erythrodermie bei 22q11-deletionssyndrom. Medizinische Klinik, 100: 275-278.
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  242. Papakonstantinou, E., A.J. Aletras, E. Glass, P. Tsogas and A. Dionyssopoulos et al., 2005. Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin. J. Invest. Dermatol., 125: 673-684.
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  243. Munster, U., C. Nakamura, A. Haberland, K. Jores and W. Mehnert et al., 2005. RU 58841-myristate-a prodrug for topical treatment of acne and androgenetic alopecia. Pharmazie, 60: 8-12.
  244. Husak, R., C.C. Zouboulis, C. Sander‐Bahr, M. Hummel and C.E. Orfanos, 2005. Refractory human papillomavirus‐associated oral warts treated topically with 1-3% cidofovir solutions in human immunodeficiency virus type 1-infected patients. Br. J. Dermatol., 152: 590-591.
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  245. Georgel, P., K. Crozat, X. Lauth, E. Makrantonaki and H. Seltmann et al., 2005. A TLR2-responsive lipid effector pathway protects mammals against Gram-positive bacterial skin infections. Infect. Immun., 73: 4512-4521.
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  246. Bekou, V., S. Thoma-Uszynski, O. Wendler, W. Uter and S. Schwietzke et al., 2005. Detection of laminin 5-specific auto-antibodies in mucous membrane and bullous pemphigoid sera by ELISA. J. Invest. Dermatol., 124: 732-740.
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  247. Assaf, C., S.E. Coupland, M. Hummel, K. Jahnke and S. Mostafafivar et al., 2005. Relapse of a primary dural marginal-zone B-lymphoma presenting as massive unilateral lymphoedema of the leg. Lancet Oncol., 6: 187-189.
  248. Adams, J., E. Kiss, A.B.V. Arroyo, M. Bonrouhi and Q. Sun et al., 2005. 13-cis retinoic acid inhibits development and progression of chronic allograft nephropathy. Am. J. Pathol., 167: 285-298.
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  249. Zouboulis, C.C., A.D. Rosenberger, T. Forster, G. Beller, M. Kratzsch and D. Felsenberg, 2004. Modification of a device and its application for intralesional cryosurgery of old recalcitrant keloids. Arch. Dermatol., 140: 1293-1294.
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  250. Zouboulis, C.C., 2004. Extended venous thrombosis in Adamantiades-Behcet's disease. Eur. J. Dermatol., 14: 268-271.
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  251. Turnbull, J.R., C.H. Assaf, C.C. Zouboulis and B. Tebbe, 2004. Bilateral naevus of Ota: A rare manifestation in a Caucasian. J. Eur. Acad. Dermatol. Venereol., 18: 353-355.
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  252. Thoma-Uszynski, S., W. Uter, S. Schwietzke, S.C. Hofmann and T. Hunziker et al., 2004. BP230-and BP180-specific auto-antibodies in bullous pemphigoid. J. Invest. Dermatol., 122: 1413-1422.
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  253. Tchernev, G., C.C. Zouboulis and I. Sheitanov, 2004. [A very rare case of overlap syndrome-lupus erythematosus/lichen planus in combination with chronic ulcerative stomatitis]. Revmatologiia, 12: 33-37.
  254. Tchernev, G., C.C. Zouboulis and I. Sheitanov, 2004. [A rare case of Rowell syndrome]. Revmatologiia, 12: 38-41.
  255. Tchernev, G., C.C. Zouboulis and C. Orfanos, 2004. [Treatment of Morbus Hailey-Hailey with pimecrolimus]. Dermatol. Venereol., 153: 37-40.
  256. Ruzicka, T., F.G. Larsen, D. Galewicz, A. Horvath and P.J. Coenraads et al., 2004. Oral alitretinoin (9-cis-retinoic acid) therapy for chronic hand dermatitis in patients refractory to standard therapy: Results of a randomized, double-blind, placebo-controlled, multicenter trial. Arch. Dermatol., 140: 1453-1459.
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  257. Liebler, S., B. Uberschar, H. Kubert, S. Brems and A. Schnitger et al., 2004. The renal retinoid system: Time-dependent activation in experimental glomerulonephritis. Am. J. Physiol. Renal Physiol., 286: F458-F465.
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  258. Zouboulis, C.C., S. Nestoris, Y.D. Adler, M. Orth and C.E. Orfanos et al., 2003. A new concept for acne therapy: A pilot study with zileuton, an oral 5-lipoxygenase inhibitor. Arch. Dermatol., 139: 668-670.
    CrossRef  |  Direct Link  |  
  259. Zouboulis, C.C., S. Fimmel, J. Ortmann, J.R. Turnbull and A. Boschnakow, 2003. Sebaceous Glands. In: Neonatal Skin: Structure and Function, Hoath, S.B. and H.I. Maibach (Eds.). 2nd Edn., CRC Press, New York,ISBN: 9780824748425, pp: 59-88.
  260. Zouboulis, C.C., M. Tsukada, M. Schroder, T.C. Roos and R.A.S. Chandraratna et al., 2003. A Selective Isomerization Pattern of Isotretinoin to Tretinoin in Human Sebocytes is the Answer to the Enigma of Isotretinoin's Specific Antisebotropic Activity. In: Clinico-Experimental Advances in Dermatological Diagnostics and Treatment, Bonnekoh, B. and H. Gollnick (Eds.). Bibliomed-Verlag, Melsungen, Germany, pp: 67-80.
  261. Zouboulis, C.C., J.R. Turnbull and P.F. Muhlradt, 2003. High seroprevalence of anti-Mycoplasma fermentans antibodies in patients with malignant aphthosis. J. Invest. Dermatol., 121: 211-212.
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  262. Zouboulis, C.C., J.R. Turnbull and P. Martus, 2003. Univariate and multivariate analyses comparing demographic, genetic, clinical and serological risk factors for severe Adamantiades-Behcet's disease. Adv. Exp. Med. Biol., 528: 123-126.
  263. Zouboulis, C.C., G. Vaiopoulos, N. Marcomichelakis, G. Palimeris, I. Markidou, B. Thouas and P. Kaklamanis, 2003. Onset signs, clinical course, prognosis, treatment and outcome of adult patients with Adamantiades-Behcet's disease in Greece. Clin. Exp. Rheumatol., 21: S19-S26.
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  264. Zouboulis, C.C., 2003. Epidemiology of Adamantiades-Behcet's Disease. In: Immunology of Behcet's Disease, Zierhut, M. and S. Ohno (Eds.). Swets Publishing Co., USA., pp: 1-16.
  265. Zouboulis, C.C., 2003. Adamantiades-Behcet's Disease. In: European Handbook of Dermatological Treatments, Katsambas, A.D. and T.M. Lotti (Eds.). 2nd Edn., Springer, Berlin, Heidelberg, pp: 16-26.
  266. Wrobel, A., H. Seltmann, S. Fimmel, K. Muller-Decker and M. Tsukada et al., 2003. Differentiation and apoptosis in human immortalized sebocytes. J. Invest. Dermatol., 120: 175-181.
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  267. Turnbull, J.R., A. Tunsch, Y.D. Adler, L. Lehmann, H. Borgmann and C.C. Zouboulis, 2003. Cardiac manifestations in four patients with Adamantiades-Behcet's disease. Adv. Exp. Med. Biol., 528: 423-426.
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  268. Niemann, C., A.B. Unden, S. Lyle, C.C. Zouboulis, R. Toftgard and F.M. Watt, 2003. Indian hedgehog and β-catenin signaling: Role in the sebaceous lineage of normal and neoplastic mammalian epidermis. Proc. Nat. Acad. Sci., 100: 11873-11880.
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  269. Muller, C.A., I. Gunaydin, N. Stubiger, H. Yazici and I. Fresko et al., 2003. Association of HLA-B51 Suballeles with Behcet's Disease in Patients of German and Turkish Origin. In: Immunology of Behcet's Disease, Zierhut, M. and S. Ohno (Eds.). Swets Publishing Co., USA., pp: 121-126.
  270. Krause, L., J.R. Turnbull, N. Torun, U. Pleyer, C.C. Zouboulis and M.H. Foerster, 2003. Interferon-alpha in the treatment of ocular Adamantiades-Behcet's disease. Adv. Exp. Med. Biol., 528: 511-519.
  271. Krause, L., F. Hoffmann, C.C. Zouboulis and M.H. Foerster, 2003. Vitrectomy and trabeculectomy combined with interferon alpha treatment in Adamantiades-Behcet's disease: A case report. Graefe's Arch. Clin. Exp. Ophthalmol., 241: 871-874.
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  272. Herrmann, S.M., Y.D. Adler, K. Schmidt‐Petersen, V. Nicaud, C. Morrison, M. Paul and C.C. Zouboulis, 2003. The concomitant occurrence of multiple epidermal cysts, osteomas and thyroid gland nodules is not diagnostic for Gardner syndrome in the absence of intestinal polyposis: A clinical and genetic report. Br. J. Dermatol., 149: 877-883.
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  273. Fechner, H., X. Wang, M. Srour, U. Siemetzki and H. Seltmann et al., 2003. A novel tetracycline-controlled transactivator-transrepressor system enables external control of oncolytic adenovirus replication. Gene Therapy, 10: 1680-1690.
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  274. Dalkowski, A., S. Fimmel, C. Beutler and C.C. Zouboulis, 2003. Cryotherapy modifies synthetic activity and differentiation of keloidal fibroblasts in vitro. Exp. Dermatol., 12: 673-681.
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  275. Choi, B.K., Y.M. Cho, S.H. Bae, C.C. Zoubaulis and Y.K. Paik, 2003. Single‐step perfusion chromatography with a throughput potential for enhanced peptide detection by matrix‐assisted laser desorption/ionization‐mass spectrometry. Proteomics, 3: 1955-1961.
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  276. Chen, W., C.C. Yang, H.M. Sheu, H. Seltmann and C.C. Zouboulis, 2003. Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes. J. Invest. Dermatol., 121: 441-447.
    CrossRef  |  Direct Link  |  
  277. Boschnakow, A., T. May, C. Assaf, B. Tebbe and C.H. Zouboulis, 2003. Ciclosporin A‐induced sebaceous gland hyperplasia. Br. J. Dermatol., 149: 198-200.
    CrossRef  |  Direct Link  |  
  278. Alpsoy, E., V. Kodelja, S. Goerdt, C.E. Orfanos and C.C. Zouboulis, 2003. Serum of patients with Behcet's disease induces classical (pro-inflammatory) activation of human macrophages in vitro. Dermatology, 206: 225-232.
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  279. Zouboulis, C.C., H. Seltmann, N. Hiroi, W. Chen and M. Young et al., 2002. Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes. Proc. Nat. Acad. Sci., 99: 7148-7153.
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  280. Zouboulis, C.C. and W. Keitel, 2002. A historical review of early descriptions of Adamantiades-Behcet's disease. J. Invest. Dermatol., 119: 201-205.
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  281. Turnbull, J.R., R. Husak, R. Treudler, C.C. Zouboulis and C.E. Orfanos, 2002. Regression of multiple viral warts in a human immunodeficiency virus‐infected patient treated by triple antiretroviral therapy. Br. J. Dermatol., 146: 330-330.
    CrossRef  |  Direct Link  |  
  282. Tsukada, M., M. Schroder, H. Seltmann, C.E. Orfanos and C.C. Zouboulis, 2002. High albumin levels restrict the kinetics of 13-cis retinoic acid uptake and intracellular isomerization to all-trans retinoic acid and inhibit its anti-proliferative effect on SZ95 sebocytes. J. Invest. Dermatol., 119: 182-185.
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  283. Marques, M., Y. Pei, M.D. Southall, J.M. Johnston and H. Arai et al., 2002. Identification of platelet-activating factor acetylhydrolase II in human skin. J. Invest. Dermatol., 119: 913-919.
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  284. Chandani, A.M.H.A., Y.D. Adler, E. Dippel and C.C. Zouboulis, 2002. Impressive skin manifestation of systemic sarcoidosis. Int. J. Dermatol., 41: 232-236.
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  285. Bohm, M., M. Schiller, S. Staender, H. Seltmann and Z. Li et al., 2002. Evidence for expression of melanocortin-1 receptor in human sebocytes in vitro and in situ. J. Invest. Dermatol., 118: 533-539.
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  286. Alpsoy, E., M.A. Ciftcioglu, I. Keser, E.M. De Villiers and C.C. Zouboulis, 2002. Epidermodysplasia verruciformis associated with neurofibromatosis type 1: Coincidental association or model for understanding the underlying mechanism of the disease? Br. J. Dermatol., 146: 503-507.
    CrossRef  |  Direct Link  |  
  287. Adler, Y.D., S. Jovanovic, A. Jivanjee, L. Krause and C.C. Zouboulis, 2002. Adamantiades-Behcet's disease with inner ear involvement. Clin. Exp. Rheumatol., 20: S40-S42.
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  288. Zouboulis, C.C., I. Kotter, D. Djawari, W. Kirch and P.K. Kohl et al., 2001. Adamantiades-Behcet's Disease: Epidemiology in Germany and in Europe. In: Behcet's Disease: A Guide to its Clinical Undestanding, Textbook and Atlas, Lee, S., D. Bang, E.S. Lee and S. Sohn (Eds.). Springer, Berlin, Heidelberg, pp: 157-169.
  289. Zouboulis, C.C., C.A. Stratakis, H.P.M. Gollnick and C.E. Orfanos, 2001. Keratosis pilaris/ulerythema ophryogenes and 18p deletion: is it possible that theLAMA1 gene is involved? J. Med. Genet., 38: 127-128.
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  290. Zouboulis, C.C., 2001. Cryosurgery in the Treatment of Keloids and Hypertrophic Scars. In: Basics of Cryosurgery, Korpan, N.N. (Ed.). Springer, New York, pp: 253-269.
  291. Zouboulis, C., 2001. Exploration of retinoid activity and the role of inflammation in acne: Issues affecting future directions for acne therapy. J. Eur. Acad. Dermatol. Venereol., 15: 63-67.
    CrossRef  |  Direct Link  |  
  292. Meljanac, N., E. Dippel and C.C. Zouboulis, 2001. Superimposed primary chancre in a patient with Adamantiades-Behcet's disease. Rev. Ser. Rheumatol., 2: 18-19.
  293. Kotter, I, I. Gunaydin, N. Stubiger, H. Yazici and I. Fresko et al., 2001. Comparative analysis of the association of HLA-B*51x and its suballeles with Behcet's disease in patients of German and Turkish origin. Tissue Antigens, 58: 166-170.
  294. Fritsch, M., C.E. Orfanos and C.C. Zouboulis, 2001. Sebocytes are the key regulators of androgen homeostasis in human skin. J. Invest. Dermatol., 116: 793-800.
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  295. Fimmel, S., A. Saborowski, C.E. Orfanos and C.C. Zouboulis, 2001. Development of efficient transient transfection systems for introducing antisense oligonucleotides into human epithelial skin cells. Hormone Res. Paediatrics, 54: 306-311.
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  296. Dippel, E., C.E. Orfanos and C. Zouboulis, 2001. Linear IgA dermatosis presenting with erythema annulare centrifugum lesions: Report of three cases in adults. J. Eur. Acad. Dermatol. Venereol., 15: 167-170.
    CrossRef  |  Direct Link  |  
  297. Adler, Y.D., U. Mansmann and C.C. Zouboulis, 2001. Mycophenolate mofetil is ineffective in the treatment of mucocutaneous Adamantiades-Behcet's disease. Dermatology, 203: 322-324.
    CrossRef  |  Direct Link  |  
  298. Adler, Y.D., C.C. Zouboulis, C.C. Geilen and C.E. Orfanos, 2001. Eine seltene Variante des SAHA Syndroms. Z Hautkr, 76: 327-328.
  299. Zouboulis, C.H., L. Derumeaux, J. Decroix, B. Maciejewska‐Udziela, F. Cambazard and A. Stuhlert, 2000. A multicentre, single‐blind, randomized comparison of a fixed clindamycin phosphate/tretinoin gel formulation (Velac®) applied once daily and a clindamycin lotion formulation (Dalacin T®) applied twice daily in the topical treatment of acne vulgaris. Br. J. Dermatol., 143: 498-505.
    CrossRef  |  Direct Link  |  
  300. Zouboulis, C.C., J. Katsantonis, R. Ketteler, R. Treudler and E. Kaklamani et al., 2000. Adamantiades-Behcet's disease: Interleukin-8 is increased in serum of patients with active oral and neurological manifestations and is secreted by small vessel endothelial cells. Arch. Dermatol. Res., 292: 279-284.
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  301. Tsukada, M., M. Schroder, T.C. Roos, R.A. Chandraratna and U. Reichert et al., 2000. 13-cis retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans retinoic acid and binding to retinoid acid receptors. J. Invest. Dermatol., 115: 321-327.
    Direct Link  |  
  302. Kontochristopoulos, G.J., P.G. Stavropoulos, K. Krasagakis, S. Goerdt and C.C. Zouboulis, 2000. Differentiation between Merkel cell carcinoma and malignant melanoma: An immunohistochemical study. Dermatology, 201: 123-126.
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  303. Klemke, C.D., S. Nestoris, L.U. Wolfer, S. Krengel, C.C. Zouboulis, B. Tebbe and S. Goerdt, 2000. Radiogene akne. Der Hautarzt, 51: 187-191.
    CrossRef  |  Direct Link  |  
  304. Katsantonis, J., Y. Adler, C.E. Orfanos and C.C. Zouboulis, 2000. Adamantiades-Behcet's disease: Serum IL-8 is a more reliable marker for disease activity than C-reactive protein and erythrocyte sedimentation rate. Dermatology, 201: 37-39.
    CrossRef  |  Direct Link  |  
  305. Chen, W., J.O. Sass, H. Seltmann, H. Nau, C.E. Orfanos and C.C. Zouboulis, 2000. Biological effects and metabolism of 9-cis-retinoic acid and its metabolite 9, 13-di-cis-retinoic acid in HaCaT keratinocytes in vitro: Comparison with all-trans-retinoic acid. Arch. Dermatol. Res., 292: 612-620.
    CrossRef  |  Direct Link  |  
  306. Almond-Roesler, B. and C.C. Zouboulis, 2000. Successful treatment of solar lentigines by brief gentle cryosurgery using a Kryomed® device. Br. J. Dermatol., 143: 216-218.
    CrossRef  |  Direct Link  |  
  307. Zouboulis, C.C., P.G. Stavropoulos and K.D. Wolff, 1999. Benign Tumours of the Oral Mucosa, Muscle, Nervous System, Bone and Cartilage. In: Oral Diseases: Textbook and Atlas, Lotti, T.M., L.C. Parish and R.S. Rogers (Eds.). Springer, New York, pp: 291-313.
  308. Zouboulis, C.C., H. Seltmann, J.O. Sass, R. Ruhl and C. Plum et al., 1999. Retinoid signaling by all-trans retinoic acid and all-trans retinoyl-β-D-glucuronide is attenuated by simultaneous exposure of human keratinocytes to retinol. J. Invest. Dermatol., 112: 157-164.
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  309. Zouboulis, C.C., H. Seltmann, H. Neitzel and C.E. Orfanos, 1999. Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95). J. Invest. Dermatol., 113: 1011-1020.
  310. Zouboulis, C.C., A.D. Rosenberger, Y. Adler and C.E. Orfanos, 1999. Treatment of solar lentigo with cryosurgery. Acta Derm Venereol., 79: 489-490.
  311. Zouboulis, C.C., 1999. Epidemiology of adamantiades-behcet's disease. Ann. Med. Interne, 150: 488-498.
  312. Zouboulis, C.C., 1999. Adamantiades-Behcet's Disease. In: European Handbook of Dermatological Treatments, Katsambas, A.D. and T. Lotti (Eds.). Springer, New York, pp: 21-30.
  313. Treudler, R., C.E. Orfanos and C.C. Zouboulis, 1999. Twenty-eight cases of juvenile-onset adamantiades-behcet disease in Germany. Dermatology, 199: 15-19.
    CrossRef  |  Direct Link  |  
  314. Tavakkol, A., J. Varani, J.T. Elder and C.C. Zouboulis, 1999. Maintenance of human skin in organ culture: Role for insulin-like growth factor-1 receptor and epidermal growth factor receptor. Arch Dermatol. Res., 291: 643-651.
    CrossRef  |  Direct Link  |  
  315. Meljanac, N., E. Dippel and C.C. Zouboulis, 1999. Superimposed primary chancre in a patient with Adamantiades-Behcet's disease. Sex Transm Infect., 75: 124-125.
  316. Duong, T.N.Y., U. Blume-Peytavi, S. Krengel, C.C. Zouboulis and C.E. Orfanos, 1999. Rheumatoid nodules developing under methotrexate treatment for rheumatoid arthritis. Acta Derm Venereol., 79: 397-398.
  317. Dippel, E., A. Rosenberger and C.C. Zouboulis, 1999. Distant cutaneous manifestation of Crohn's disease presenting as a granulomatous erysipelas-like lesion. J. Eur. Acad. Dermatol. Venereol., 12: 65-66.
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  318. Dalkowski, A., D. Schuppan, C.E. Orfanos and C.C. Zouboulis, 1999. Increased expression of tenascin C by keloids in vivo and in vitro. Br. J. Dermatol., 141: 50-56.
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  319. Zouboulis, C.C., M. Schmuth, S. Doepfmer, E. Dippel and C.E. Orfanos, 1998. Extracorporeal photopheresis of cutaneous t-cell lymphoma is associated with reduction of peripheral CD4+ T lymphocytes. Dermatology, 196: 305-308.
    CrossRef  |  Direct Link  |  
  320. Zouboulis, C.C., L. Xia, H. Akamatsu, H. Seltmann and M. Fritsch et al., 1998. The human sebocyte culture model provides new insights into development and management of seborrhoea and acne. Dermatology, 196: 21-31.
    CrossRef  |  Direct Link  |  
  321. Zouboulis, C.C. and C.E. Orfanos, 1998. Treatment of adamantiades-behcet disease with systemic interferon α. Arch. Dermatol., 134: 1010-1016.
    CrossRef  |  
  322. Pfrommer, C., B. Tebbe, C.A. Tidona, U. Wolfer and S. Krengel et al., 1998. Progressive HHV-8-positive classic Kaposi's sarcoma: Rapid response to interferon α-2a but persistence of HHV-8 DNA sequences in lesional skin. Br. J. Dermatol., 139: 516-519.
    CrossRef  |  Direct Link  |  
  323. Paraskevaidis, A., N. Drakoulis, I. Roots, C.E. Orfanos and C.C. Zouboulis, 1998. Polymorphisms in the human cytochrome P-450 1A1 gene (CYP1A1) as a factor for developing acne. Dermatology, 196: 171-175.
    CrossRef  |  Direct Link  |  
  324. Dippel, E., C.C. Zouboulis, B. Tebbe and C.E. Orfanos, 1998. Myopathic syndrome associated with long-term recombinant interferon α treatment in 4 patients with skin disorders. Arch. Dermatol., 134: 880-881.
  325. Chen, W., C.C. Zouboulis, M. Fritsch, V. Kodelja and C.E. Orfanos, 1998. Heterogeneity and quantitative differences of type 1 5α-reductase expression in cultured skin epithelial cells. Dermatology, 196: 51-52.
    CrossRef  |  Direct Link  |  
  326. Chen, W., C.C. Zouboulis, M. Fritsch, U. Blume-Peytavi and V. Kodelja et al., 1998. Evidence of heterogeneity and quantitative differences of the type 1 5α-reductase expression in cultured human skin cells-evidence of its presence in melanocytes. J. Invest. Dermatol., 110: 84-89.
    CrossRef  |  Direct Link  |  
  327. Zouboulis, C.C., I. Kotter, D. Djawari, W. Kirch and P.K. Kohl et al., 1997. Epidemiological features of Adamantiades-Behcet's disease in Germany and in Europe. Yonsei Med. J., 38: 411-422.
    PubMed  |  
  328. Stavwpoulos, P.G., C.C. Zouboulis, C. Trautmann and C.E. Orfanos, 1997. Symmetric lipomatoses in female patients. Dermatology, 194: 26-31.
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  329. Stavropoulos, P.O., J.F. Leonforte, H. Gollnick, L. Bruckner-Tuderman and C.C. Zouboulis, 1997. Lichen planus pemphigoides: Another paraneoplastic bullous disease? J. Eur. Acad. Dermatol. Venereol., 9: 62-67.
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  330. Krasagakis, K., B. Almond-Roesler, C.C. Zouboulis, B. Tebbe, E. Wartenberg, K.D. Wolff and C.E. Orfanos, 1997. Merkel cell carcinoma: Report of ten cases with emphasis on clinical course, treatment and in vitro drug sensitivity. J. Am. Acad. Dermatol., 36: 727-732.
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  331. Chen, W., M. Schramm and C.C. Zouboulis, 1997. Generalized lichen nitidus. J. Am. Acad. Dermatol., 36: 630-631.
  332. Blume-Peytavi, U., W. Chen, N. Djemadji, C.C. Zouboulis and S. Goerdt, 1997. Eosinophilic pustular folliculitis (Ofuji's disease). J. Am. Acad. Dermatol., 37: 259-262.
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  333. Zouboulis, C.C., U. Blume-Peytavi, T. Lennert, P.G. Stavropoulos and A. Schwarz et al., 1996. Fulminant metastatic calcinosis with cutaneous necrosis in a child with end-stage renal disease and tertiary hyperparathyroidism. Br. J. Dermatol., 135: 617-622.
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  334. Zouboulis, C.C., J.J. Voorhees, C.E. Orfanos and A. Tavakkol, 1996. Topical all-trans Retinoic Acid (RA) induces an early, coordinated increase in RA-inducible skin-specific gene/psoriasin and cellular RA-binding protein II mRNA levels which precedes skin erythema. Arch. Dermatol. Res., 288: 664-669.
    CrossRef  |  Direct Link  |  
  335. Zouboulis, C.C., 1996. Morbus adamantiades-behcet in deutschland: Historischer ruckblick und aktueller Kenntnisstand. Z Hautk., 71: 491-501.
  336. Zouboulis, C., 1996. Human Sebocyte Cultures are an Appropriate Model for Studying Sebaceous Gland Function at the Cellular Level. In: Hair Research for the Next Millenium, Van Neste, D. and V.A. Randall (Eds.)., Elsevier, Amsterdam, pp: 387-392.
  337. Wolfer, L.U., S. Goerdt, K. Schroder, C.C. Zouboulis and C.E. Orfanos, 1996. Interferon-α-induzierte psoriasis vulgaris. D Haut., 47: 124-128.
    CrossRef  |  Direct Link  |  
  338. Treudler, R., C.C. Zouboulis, P. Buttner, M. Detmar and C.E. Orfanos, 1996. Enhanced interaction of patients' lymphocytes with human dermal microvascular endothelial cell cultures in active adamantiades-behcet disease. Arch. Dermatol., 132: 1323-1329.
    CrossRef  |  Direct Link  |  
  339. Krasagakis, K., C.C. Zouboulis, M. Owsianowski, J. Ramaker, C. Trautmann, B. Tebbe and C.E. Orfanos, 1996. Remission of scleromyxoedema following treatment with extracorporeal photopheresis. Br. J. Dermatol., 135: 463-466.
    CrossRef  |  Direct Link  |  
  340. Jockers-Scherubl, M.C., C.C. Zouboulis, F. Boegner and R. Hellweg, 1996. Is nerve growth factor a serum marker for neurological and psychiatric complications in Behcet's disease? Lancet, 347: 982-982.
    PubMed  |  
  341. Husak, R., H. von Briesen, U. Dietrich, C.C. Zouboulis and C.E. Orfanos, 1996. Rapidly progressive infection and Kaposi's sarcoma in patient with a novel syncytium-inducing HIV-B variant. Lancet, 348: 1107-1108.
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  342. Zouboulis, C.C., U. Blume, H. Gollnick and C.E. Orfanos, 1995. Cholinergic urticaria simulating aquagenic urticaria: A case report with lesions only occurring after contact with hot water. J. Eur. Acad. Dermatol. Venereol., 4: 62-65.
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  343. Jorizzo, J.L., J.L. Abernethy, W.L. White, H.C. Mangelsdorf and C.C. Zouboulis et al., 1995. Mucocutaneous criteria for the diagnosis of Behcet's disease: An analysis of clinicopathologic data from multiple international centers. J. Am. Acad. Dermatol., 32: 968-976.
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  344. Armstrong, R., W.J. Cunliffe, P. Fritsch, W.E. Lambert and C.C. Zouboulis et al., 1995. Pharmacology and side effects of retinoid therapy. J. Am. Acad. Dermatol., 27: S45-S46.
  345. Zouboulis, C.C., U. Blume, M.S.P. Fernandez, H. Mielitz and C.E. Orfanos, 1994. Outcomes of cryosurgery in patients with basal cell carcinoma. Skin Cancer, 9: 7-22.
  346. Zouboulis, C.C., H.P.M. Gollnick and C.E. Orfanos, 1994. Livedo racemosa due to cholesterol crystal embolization. Eur. J. Dermatol., 4: 569-570.
  347. Zouboulis, C.C., C.A. Stratakis, G. Rinck, R.D. Wegner, H. Gollnick and C.E. Orfanos, 1994. Ulerythema ophryogenes and keratosis pilaris in a child with monosomy 18p. Pediatr. Dermatol., 11: 172-175.
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  348. Zouboulis, C.C., A. Krieter, H. Gollnick, D. Mischke and C.E. Orfanos, 1994. Progressive differentiation of human sebocytes in vitro is characterized by increasing cell size and altering antigen expression and is regulated by culture duration and retinoids. Exp. Dermatol., 3: 151-160.
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  349. Zouboulis, C.C. and A. Tavakkol, 1994. Storage phosphor imaging technique improves the accuracy of RNA quantitation using 32P-labeled cDNA probes. Biotechniques, 16: 290-294.
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  350. Zouboulis, C., H. Akamatsu, K. Stephanek and C.E. Orfanos, 1994. Androgens affect the activity of human sebocytes in culture in a manner dependent on the localization of the sebaceous glands and their effect is antagonized by spironolactone. Skin Pharmacol. Physiol., 7: 33-40.
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  351. Tavakkol, A., C.C. Zouboulis, E.A. Duell and J.J. Voorhees, 1994. A retinoic acid-inducible skin-specific gene (RIS-1/psoriasin): Molecular cloning and analysis of gene expression in human skinin vivo and cultured skin cellsin vitro. Mol. Biol. Rep., 20: 75-83.
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  352. Haligah, C.E., C.C. Zouboulis, M.B. Abdel‐Naser, M. Detmar, G. Ehlers and H. Gollnick, 1994. Idiopathic anetoderma with concomitant lesions of the Jadassohn‐Pellizzari and the Schweninger‐Buzzi types. J. Eur. Acad. Dermatol. Venereol., 3: 387-393.
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  353. Blume, U., M.P. Schon, C.C. Zouboulis, M. Detmar and C.E. Orfanos, 1994. Vellus hair follicle-derived keratinocyte culture: A new experimental model in human hair research. Skin Pharmacol. Physiol., 7: 27-32.
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  354. Blume‐Peytavi, U., C.C. Zouboulis, H. Jacobi, A. Scholz, S. Bisson and C.E. Orfanos, 1994. Successful outcome of cryosurgery in patients with granuloma annulare. Br. J. Dermatol., 130: 494-497.
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  355. Akai, Y., H. Akamatsu, S. Ri, A. Ito, C.C. Zouboulis and Y. Asada, 1994. [Influence of free fatty acids on the proliferation of cultured human sebocytes in vitro]. Jpn. J. Dermatol., 104: 647-649.
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  356. Zouboulis, C.C., U. Blume, P. Buttner and C.E. Orfanos, 1993. Outcomes of cryosurgery in keloids and hypertrophic scars: A prospective consecutive trial of case series. Archiv. Dermatol., 129: 1146-1151.
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  357. Zouboulis, C.C., P. Buttner, B. Tebbe and C.E. Orfanos, 1993. Anticardiolipin antibodies in Adamantiades-Behcet's disease. Br. J. Dermatol., 128: 281-284.
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  358. Zouboulis, C.C., B.P. Korge, D. Mischke and C.E. Orfanos, 1993. Altered proliferation, synthetic activity and differentiation of cultured human sebocytes in the absence of vitamin A and their modulation by synthetic retinoids. J. Investigat. Dermatol., 101: 628-633.
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  359. Zouboulis, C.C., 1993. Intravenous heparin possibly induces intravascular coagulation necrosis of the skin through the in vivo formation of the heparin-precipitable fraction of plasma in certain circumstances. Eur. J. Dermatol., 3: 242-243.
  360. Blume, U., C. Zouboulis, B. Bratzke, S. Singel and C. Orfanos, 1993. Painful bruising syndrome: A psychogenic dermatosis. Eur. J. Dermatol., 3: 364-366.
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  361. Akamatsu, H., C.C. Zouboulis and C.E. Orfanos, 1993. Spironolactone directly inhibits proliferation of cultured human facial sebocytes and acts antagonistically to testosterone and 5α-dihydrotestosterone in vitro. J. Investigat. Dermatol., 100: 660-662.
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  362. Zouboulis, C.C., S. Biczo, H. Gollnick, H.J. Reupke and G. Rinck et al., 1992. Elephantiasis nostras verrucosa: Beneficial effect of oral etretinate therapy. Br. J. Dermatol., 127: 411-416.
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  363. Zouboulis, C.C., P. Buttner and C.E. Orfanos, 1992. Systemic interferon gamma as adjuvant therapy for refractory anogenital warts: A randomized clinical trial and meta-analysis of the available data. Arch. Dermatol., 128: 1413-1414.
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  364. Zouboulis, C.C., 1992. Sebocyte cultures: How they can improve our understanding of diseases of the sebaceous glands. Retinoids Today Tomorrow, 26: 6-12.
  365. Zouboulis, C.C., 1992. Sebaceous cells in monolayer culture. In Vitro Cell. Dev. Biol. Anim., 28: 699-699.
    PubMed  |  Direct Link  |  
  366. Gollnick, H., C.C. Zouboulis and C.E. Orfanos, 1992. Cryofibrinogenemia, cardiolipin antibodies and diabetes mellitus as a cause of cutaneous intravascular coagulation necrosis. Skin Res., 34: 72-76.
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  367. Garbe, C., E.D. Kreuser, C.C. Zouboulis, R. Stadler and C.E. Orfanos, 1992. Combined treatment of metastatic melanoma with interferons and cytotoxic drugs. Semin Oncol., 19: 63-69.
  368. Akamatsu, H., C.C. Zouboulis, S. Nishijima, Y. Asada and C.E. Orfanos, 1992. [Inhibitory action of spironolactone on DHT-stimulated proliferation of human sebocytes in vitro: A possible anti-acne mechanism of spironolactone]. Acta Dermatol., 87: 557-560.
  369. Akamatsu, H., C.C. Zouboulis and C.E. Orfanos, 1992. [Androgens influence the proliferation of human sebocytes in vitro]. Jpn. J. Dermatol., 102: 47-50.
  370. Akamatsu, H., C.C. Zouboulis and C.E. Orfanos, 1992. Influence of androgens on the proliferation of human sebocytes in vitro. Skin Res., 34: 127-130.
  371. Akamatsu, H., C.C. Zouboulis and C.E. Orfanos, 1992. Control of human sebocyte proliferation in vitro by testosterone and 5-α-dihydrotestosterone is dependent on the localization of the sebaceous glands. J. Investigat. Dermatol., 99: 509-511.
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  372. Abdel-Naser, M.B., C.C. Zouboulis and I. Anagnostopoulos, 1992. Subungual exostosis. Eur. J. Dermatol., 2: 345-347.
  373. Zouboulis, C.C., R. Stadler, H. Ikenberg and C.E. Orfanos, 1991. Short-term systemic recombinant interferon-γ treatment is ineffective in recalcitrant condylomata acuminata. J. Am. Acad. Dermatol., 24: 302-303.
  374. Zouboulis, C.C., L. Xia, M. Detmar, B. Bogdanoff, G. Giannakopoulos, H. Gollnick and C.E. Orfanos, 1991. Culture of human sebocytes and markers of sebocytic differentiation in vitro. Skin Pharmacol. Physiol., 4: 74-83.
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  375. Zouboulis, C.C., H. Gollnick, S. Weber, H.H. Peter and C.E. Orfanos, 1991. Intravascular coagulation necrosis of the skin associated with cryofibrinogenemia, diabetes mellitus and cardiolipin autoantibodies. J. Am. Acad. Dermatol., 25: 882-888.
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  376. Zouboulis, C.C., C. Garbe, K. Krasagakis, S. Kruger and C.E. Orfanos, 1991. A fluorometric rapid microassay to identify anti-proliferative compounds for human melanoma cells in vitro. Melanoma Res., 1: 91-96.
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  377. Zouboulis, C.C., B. Korge, H. Akamatsu, L. Xia, S. Schiller, H. Gollnick and C.E. Orfanos, 1991. Effects of 13-cis-retinoic acid, all-trans-retinoic acid and acitretin on the proliferation, lipid synthesis and keratin expression of cultured human sebocytes in vitro. J. Investigat. Dermatol., 96: 792-797.
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  378. Xia, L., C. Zouboulis, K. Krasagakis and C.E. Orfanos, 1991. [Culture techniques for human melanocytes]. Chin. J. Dermatol., 24: 120-121.
  379. Xia, L., C. Zouboulis and C.E. Orfanos, 1991. [Technique for isolation of human sebaceous glands and cultivation of human sebocytes]. Chin. J. Dermatol., 24: 399-400.
  380. Zouboulis, C.C., K. Schroder, C. Garbe, K. Krasagakis, S. Kruger and C.E. Orfanos, 1990. Cytostatic and cytotoxic effects of rTNF-α on sensitive human melanoma cells in vitro may result in selection of cells with enhanced markers of malignancy. J. Invest. Dermatol., 95: 223S-230S.
  381. Zouboulis, C.C., C. Garbe, S. Kruger and C.E. Orfanos, 1990. Interferons and melanoma: Comparison of the cytostatic and cytotoxic effects of natural and recombinant interferons, tumor necrosis factor-α and their combinations on human melanoma cells in vitro. Skin Cancer, 5: 137-145.
  382. Garbe, C., K. Krasagakis, C.C. Zouboulis, K. Schroder, S. Kruger and C.E. Orfanos, 1990. Antitumor activities of interferon-alpha, -β and -γ and their combinations on human melanoma cells in vitro. Changes of proliferation, melanin synthesis and immunophenotype. J. Invest. Dermatol 95: 231S-237S.
  383. Zouboulis, C., C. Garbe and C.E. Orfanos, 1989. Factors influencing the in vitro growth of human melanoma cell lines. Skin Cancer, 4: 63-72.
  384. Xia, L., C. Zouboulis, M. Detmar, A. Mayer-da-Silva, R. Stadler and C.E. Orfanos, 1989. Isolation of human sebaceous glands and cultivation of sebaceous gland-derived cells as an in vitro model. J. Investigat. Dermatol., 93: 315-321.
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  385. Zouboulis, C. and A. Tsourdis, 1988. [Acute necrotising pancreatitis presented as diabetic coma]. Hellenic Armed Forces Med. Rev., 22: 49-52.
  386. Yatromanolakis, N., C. Zouboulis, K. Volikas and K. Koulouris, 1988. [Tuberculous infection rate in young ages during the period 1981-1986 in Greece]. Iatriki, 54: 437-441.