Dr. Olivier Renaudet
Research ScientistUniversity Grenoble Alpes, France
Highest Degree
PostDoc Fellow in Organic Chemistry from University of Bern, Switzerland
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University Grenoble Alpes, France
Biography
Olivier Renaudet received his PhD in 2002 in the field of peptide and carbohydrate chemistry in the group of Prof. P. Dumy at the Université Joseph Fourier, Grenoble (France). Thereafter, he pursued postdoctoral researches in the group of Prof. J.-L. Reymond at the University of Berne (Switzerland) then he returned to Grenoble to obtain an Assistant Professor (2004) and a full Professor position (2012) at the Department of Molecular Chemistry. He was awarded junior member at the Institut Universitaire de France in 2011 and ERC Consolidator Grant in 2014. He has co-edited a themed issue on “Multivalent Scaffolds in Glycoscience” published in the Chemical Society Reviews (RSC Publishing) in 2013. His current research activities focus on the development of multi-click approaches to synthesize multi-functional homo- and heteroglycoclusters as antitumoral synthetic vaccines, nanovectors or anti-pathogenic agents.
Area of Interest:
Chemistry
100%
Carbohydrate Chemistry
62%
Peptide Chemistry
90%
Carbohydrate-Protein Interactions
75%
Synthetic Vaccines
55%
Research Publications in Numbers
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Chapters
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Articles
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Selected Publications
- Thomas, B., M. Fiore, G.C. Daskhan, N. Spinelli and O. Renaudet, 2015. A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds. Chem. Commun., 51: 5436-5439.
Direct Link | - Daskhan, G.C., N. Berthet, B. Thomas, M. Fiore and O. Renaudet, 2015. Multivalent glycocyclopeptides: toward nano-sized glycostructures. Carbohydr. Res., 405: 13-22.
CrossRef | Direct Link | - Ulrich, S., D. Boturyn, A. Marra, O. Renaudet and P. Dumy, 2014. Oxime-bond ligation: a chemoselective click-type reaction for accessing multifunctional biomolecular constructs. Chem. Eur. J., 20: 34-41.
CrossRef | Direct Link | - Thakar, D., E. Migliorini, L.C. Guerente, R. Sadir and H.L. Jacob et al., 2014. A quartz crystal microbalance method to study the terminal functionalization of glycosaminoglycans. Chem. Commun., 50: 15148-15151.
Direct Link | - Rozbesky, D., J. Krejzova, K. Krenek, J. Prchal and R. Hrabal et al., 2014. Reevaluation of binding properties of recombinant lymphocyte receptors NKR-P1A and CD69 to chemically synthesized glycans and peptides. Int. J. Mol. Sci., 15: 1271-1283.
CrossRef | Direct Link | - Richichi, B., B. Thomas, M. Fiore, R. Bosco and H. Qureshi et al., 2014. A cancer therapeutic vaccine based on clustered Tn-antigen mimetics induces strong antibody-mediated protective immunity. Angew. Chem. Int. Edu., 53: 11917-11920.
CrossRef | Direct Link | - Nativi, C. and O. Renaudet, 2014. Recent progress in antitumoral synthetic vaccines. ACS Med. Chem. Lett., 5: 1176-1178.
Direct Link | - Krenek, K., R. Gazak, G.C. Daskhan, J. Garcia and M. Fiore et al. 2014. Access to bifunctionalizedbiomolecular platforms using oxime ligation. Carbohydr. Res., 393: 9-14.
- Ghirardello, M., K. Oberg, S. Staderini, O. Renaudet and N. Berthet et al., 2014. Thiol-ene and thiol-yne based synthesis of glycodendrimers as nanomolar inhibitors of wheat germ agglutinin. J. Polym. Sci., 52: 2422-2433.
CrossRef | Direct Link | - Fiore, M., N. Berthet, O. Renaudet and V. Barbier, 2014. New glycopolymers as multivalent systems for lectin recognition. Med. Chem. Commun., 5: 1202-1207.
CrossRef | Direct Link | - Ulrich, S., P. Dumy, D. Boturyn and O. Renaudet, 2013. Engineering of biomolecules for sensing and imaging applications. J. Drug Deliv. Sci. Tech., 23: 5-15.
CrossRef | Direct Link | - Thomas, B., N. Berthet, J. Garcia, P. Dumy and O. Renaudet, 2013. Expanding the scope of oxime ligation: facile synthesis of large cyclopeptide-based glycodendrimers. Chem. Commun., 49: 10796-10798.
CrossRef | Direct Link | - Renaudet, O. and R. Roy, 2013. Multivalent scaffolds in glycoscience: an overview. Chem. Soc. Rev., 42: 4515-4517.
CrossRef | Direct Link | - Galan, M.C., P. Dumy and O. Renaudet, 2013. Multivalent glycol(cyclo)peptides. Chem. Soc. Rev., 42: 4599-4612.
- Fiore, M., N. Berthet, A. Marra, E. Gillon and P. Dumy et al., 2013. Tetravalent glycocyclopeptide with nanomolar affinity to wheat germ agglutinin. Org. Biomol. Chem., 11: 7113-7122.
CrossRef | Direct Link | - Fiore, M., B. Thomas, V. Dulery, P. Dumy and O. Renaudet, 2013. Synthesis of multi-antigenic platforms as vaccine candidates against cancers. New J. Chem., 37: 286-289.
CrossRef | Direct Link | - Berthet, N., B. Thomas, I. Bossu, E. Dufour and E. Gillon et al., 2013. High affinity glycodendrimers for the lectinLecB from Pseudomonas aeruginosa. Bioconjugate Chem., 24: 1598-1611.
CrossRef | Direct Link | - Bernardi, A., J.J. Barbero, A. Casnati, C.D. Castro and T. Darbre et al., 2013. Multivalent glycoconjugates as anti-pathogenic agents. Chem. Soc. Rev., 42: 4709-4727.
CrossRef | Direct Link | - Thomas, B., M. Fiore, I. Bossu, P. Dumy and O. Renaudet, 2012. Synthesis of heteroglycoclusters using orthogonal chemoselective ligations. Beilstein J. Org. Chem., 8: 421-427.
CrossRef | Direct Link | - Conte, M.L., S. Staderini, A. Chambery, N. Berthet and P. Dumy et al., 2012. Glycoside and peptide clustering around the octasilsesquioxane scaffold via photoinduced free-radical thiol-ene coupling. The observation of a striking glycoside cluster effect. Org. Biomol. Chem., 10: 3269-3277.
CrossRef | Direct Link | - Renaudet, O., C. Philouze, C. Bailly, A. Durif and P. Dumy, 2011. X-ray structure of the key synthetic intermediate of a cancer-related sialyl-Tn antigen analogue. J. Chem. Crystallog., 41: 204-208.
CrossRef | Direct Link | - Pujol, A., M. Cuillel, O. Renaudet, C. Lebrun and P. Charbonnier et al., 2011. Hepatocyte targeting and intracellular copper chelation by a thiol-containing glycocyclopeptide. J. Am. Chem. Soc., 133: 286-296.
CrossRef | Direct Link | - Galibert, M., O. Renaudet, P. Dumy and D. Boturyn, 2011. Access to biomolecular assemblies via one-pot triple orthogonal chemoselective ligations. Angew. Chem. Int. Edu., 50: 1901-1904.
CrossRef | Direct Link | - Bossu, I., N. Berthet, P. Dumy and O. Renaudet, 2011. Synthesis of glycocyclopeptides by click chemistry and inhibition assays with lectins. J. Carbohydr. Chem., 30: 458-468.
CrossRef | Direct Link | - Bossu, I., M. Sulc, K. Krenek, E. Dufour and J. Garcia et al., 2011. Dendri-RAFTs: a second generation of cyclopeptide-based glycoclusters. Org. Biomol. Chem., 9: 1948-1959.
CrossRef | Direct Link | - Andre, S., O. Renaudet, I. Bossu, P. Dumy and H.J. Gabius, 2011. Cyclic glycodecapeptides: how to increase their inhibitory activity and selectivity on lectin/toxin binding to a glycoprotein and cells. J. Pept. Sci., 17: 427-437.
- Renaudet, O., G. Dasgupta, I. Bettahi, A. Shi, A.B. Nesburn, P. Dumy and L.B. Mohamed, 2010. Linear and branched glyco-lipopeptides vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity. PLos One, 5: 11216-11216.
CrossRef | Direct Link | - Galibert, M., L. Sancey, O. Renaudet, J.L. Coll, P. Dumy and D. Boturyn, 2010. Application of click-click chemistry to the synthesis of new multivalent RGD conjugates. Org. Biomol. Chem., 8: 5133-5138.
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