Prof. Dr. Abdallah  Badou
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Prof. Dr. Abdallah Badou

Professor
Casablanca Hassan II University, Morocco


Highest Degree
Ph.D. in Immunology from Paul Sabatier University, France

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Area of Interest:

Biomedical Sciences
100%
Biological Chemistry
62%
Immunology
90%
Hepatology
75%
Virology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
24
Abstracts
0

Selected Publications

  1. El Azhary, K., N.T. Jouti, M. El Khachibi, M. Moutia and I. Tabyaoui et al., 2017. Anti-inflammatory potential of Capparis spinosa L. in vivo in mice through inhibition of cell infiltration and cytokine gene expression. BMC Complement. Altern. Med., Vol. 17. 10.1186/s12906-017-1569-7.
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  2. Moutia, M., K. El Azhary, A. Elouaddari, A. Al Jahid and J.J. Eddine et al., 2016. Capparis spinosa L. promotes anti-inflammatory response in vitro through the control of cytokine gene expression in human peripheral blood mononuclear cells. BMC Immunol., Vol. 17. 10.1186/s12865-016-0164-x.
    CrossRef  |  Direct Link  |  
  3. Moutia, M., F. Seghrouchni, O. Abouelazz, A. Elouaddari and A. Al Jahid et al., 2016. Allium sativum L. regulates in vitro IL-17 gene expression in human peripheral blood mononuclear cells. BMC Complement. Altern. Med., Vol. 16. 10.1186/s12906-016-1365-9.
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  4. Matza, D., A. Badou, K.G. Klemic, J. Stein and U. Govindarajulu et al., 2016. T cell receptor mediated calcium entry requires alternatively spliced Cav1.1 channels. PLoS ONE, Vol. 11. 10.1371/journal.pone.0147379.
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  5. Khachibi, M.E., B. Diakite, K. Hamzi, A. Badou and M.A. Senhaji et al., 2015. Screening of exon 11 of BRCA1 gene using the high resolution melting approach for diagnosis in Moroccan breast cancer patients. BMC Cancer, Vol. 15. 10.1186/s12885-015-1040-4.
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  6. Bellouquid, A., A. Badou and M. CH-Chaoui, 2015. New perspectives in mathematical modeling focusing on the type of the immune response and cancer eradication. Biol. Syst., Vol. 4. 10.4172/2329-6577.1000132.
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  7. Badou, A., M.K. Jha, D. Matza and R.A. Flavell, 2013. Emerging roles of L-type voltage-gated and other calcium channels in T lymphocytes. Front. Immunol., Vol. 4. 10.3389/fimmu.2013.00243.
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  8. Matza, D., A. Badou, M.K. Jha, T. Willinger and A. Antov et al., 2009. Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis. Proc. Natl. Acad. Sci. USA., 106: 9785-9790.
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  9. Jha, M.K., A. Badou, M. Meissner, J.E. McRory, M. Freichel, V. Flockerzi and R.A. Flavell, 2009. Defective survival of naive CD8+ T lymphocytes in the absence of the β3 regulatory subunit of voltage-gated calcium channels. Nat. Immunol., 10: 1275-1282.
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  10. Matza, D., A. Badou, K.S. Kobayashi, K. Goldsmith-Pestana and Y. Masuda et al., 2008. A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation. Immunity, 28: 64-74.
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  11. Watanabe, A., A. Hashmi, D.A. Gomes, T. Town, A. Badou, R.A. Flavell and W.Z. Mehal, 2007. Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology, 46: 1509-1518.
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  12. Badou, A., M.K. Jha, D. Matza, W.Z. Mehal, M. Freichel, V. Flockerzi and R.A. Flavell, 2006. Critical role for the β regulatory subunits of Cav channels in T lymphocyte function. Proc. Natl. Acad. Sci. USA., 103: 15529-15534.
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  13. Czyzyk, J., J.L. Brogdon, A. Badou, O. Henegariu, P.P. Hurlburt, R. Flavell and K. Bottomly, 2003. Activation of CD4 T cells by Raf-independent effectors of Ras. Proc. Natl. Acad. Sci. USA., 100: 6003-6008.
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  14. Bennasser, Y., A. Badou, J. Tkaczuk and E. Bahraoui, 2002. Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-α. Virology, 303: 174-180.
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  15. Savignac, M., A. Badou, M. Moreau, C. Leclerc and J.C. Guery et al., 2001. Protein kinase C-mediated calcium entry dependent upon dihydropyridine sensitive channels: A T cell receptor-coupled signaling pathway involved in IL-4 synthesis. FASEB J., 15: 1577-1579.
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  16. Savignac, M., A. Badou, C. Delmas, J.F. Subra and S.D. Cramer et al., 2001. Gold is a T cell polyclonal activator in BN and LEW rats but favors IL-4 expression only in autoimmune prone BN rats. Eur. J. Immunol., 31: 2266-2276.
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  17. Bennasser, Y., X. Contreras, M. Moreau, C. Le Clerc, A. Badou and E. Bahraoui, 2001. [HIV-1 Tat protein induces IL-10 production by human monocytes: Implications of the PKC and calcium pathway]. J. Soc. Biol., 195: 319-326, (In French).
    PubMed  |  
  18. Badou, A., M. Savignac, M. Moreau, C. Leclerc and G. Foucras et al., 2001. Weak TCR stimulation induces a calcium signal that triggers IL-4 synthesis, stronger TCR stimulation induces MAP kinases that control IFN-γ production. Eur. J. Immunol., 31: 2487-2496.
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  19. Badou, A., Y. Bennasser, M. Moreau, C. Leclerc, M. Benkirane and E. Bahraoui, 2000. Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: Implication of protein kinase C-dependent pathway. J. Virol., 74: 10551-10562.
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  20. Saoudi, A., B. Cautain, I. Bernard, A. Badou, M. Savignac, P. Druet and L. Pelletier, 1999. Cytokines and Autoimmunity. In: The Cytokine Network and Immune Functions, Theze, J. (Ed.). Chapter 26, Oxford University Press, Oxford, UK., ISBN-13: 9780198501367, pp: 321-328.
  21. Bridoux, F., A. Badou, A. Saoudi, I. Bernard and E. Druet et al., 1997. Transforming Growth Factor β (TGF-β)-dependent inhibition of T helper cell 2 (Th2)-induced autoimmunity by self-Major Histocompatibility Complex (MHC) class II-specific, regulatory CD4+ T cell lines. J. Exp. Med., 185: 1769-1775.
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  22. Badou, A., M. Savignac, M. Moreau, C. Leclerc, R. Pasquier, P. Druet and L. Pelletier, 1997. HgCl2-induced interleukin-4 gene expression in T cells involves a protein kinase C-dependent calcium influx through L-type calcium channels. J. Biol. Chem., 272: 32411-32418.
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  23. Badou, A., L. Pelletier and P. Druet, 1997. Th1/Th2 Balance in Control of Drug-Induced Autoimmunity. In: Immunointervention in Autoimmunity by Th1/Th2 Regulation, Adorini, L. (Ed.). Chapter 3, Spinger, New York, USA., ISBN-13: 9780412139215, pp: 53.
  24. Baudouin-Legros, M., A. Badou, M. Paulais, M. Hammet and J. Teulon, 1995. Hypertonic NaCl enhances adenosine release and hormonal cAMP production in mouse thick ascending limb. Am. J. Physiol.-Renal Physiol., 269: F103-F109.
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