Dr. Carlos De Cabo de la Vega
My Social Links

Dr. Carlos De Cabo de la Vega

Research Scientist
Albacete General Hospital, Spain

Highest Degree
Ph.D. in Biology Sciences from Universidad Complutense de Madrid, Spain

Share this Profile

Biography

I am a Senior Researcher (Principal Investigator) in the Translational Neuropsychophamacology Research Unit at the Albacete General Hospital (affiliated with Castilla-La Mancha University; Spain) since February 2002. I am currently the Coordinator of the Unit.

I received both my Bachelor (1988) and my PhD (1993) degrees from the Faculty of Biology, Complutense University of Madrid (Spain). I have been a visiting Scientist at the School of Biological Sciences, University of Surrey (Guildford, UK), Post-Doctoral Fellow at the Department of Psychology, University of Toronto (Toronto, ON, Canada), Reseach Associate at the Neuroscience Institute, Miguel Hernández University (Alicante, Spain) and at the Faculty of Medicine of Castilla-La Mancha University (Albacete, Spain). I have also been a part-time Assistant Professor in Histology at the Faculty of Medicine of Castilla-La Mancha University from December 2003 to September 2011 and from December 2016 to May 2017.

My reseach has mostly focussed on the cellular, molecular and genetic substrates of brain disease. Currently, epilepsy and rare neurological syndromes. Together with the neuropediatrician Dr. M. Carmen Carrascosa, also from the Hospital General Universitario de Albacete (Spain), I am affiliated with the European Network NETRE (Network Therapy Rare Epilepsies) which intends to find individualized treatments for rare genetic epileptic syndromes. Regarding rare diseases, I am currently collaborating with Dr. Javier Solera, Head of the Department of Internal Medicine of our Hospital to study clinical and molecular markers of Satoyoshi syndrome.

Area of Interest:

Molecular Sciences
100%
Biochemistry
62%
Neurology
90%
Cellular Biology
75%
Molecular Biotechnology
55%

Research Publications in Numbers

Books
1
Chapters
7
Articles
48
Abstracts
72

Selected Publications

  1. Torres, J., J. Ontañón, C. de Cabo, J. Lozano and M.Á. Requena et al., 2022. Mathematical modeling of the waning of anti-RBD IgG SARS-CoV-2 antibody titers after a two-dose BNT162b2 mRNA vaccination. medRxiv, 10.1101/2022.08.15.22278583.
    CrossRef  |  Direct Link  |  
  2. Montanaro, V.V.A., J.S.G. del Pozo, T.F. Hora, B.H. León, C. de Cabo and J. Solera, 2022. Autoimmunity in satoyoshi disease: A systematic review. medRxiv, 10.1101/2022.07.05.22277272.
    CrossRef  |  Direct Link  |  
  3. Landete-Castillejos, T., A. Rossetti, A.J. Garcia, C. de Cabo, C. Festuccia, S. Luna and L. Chonco, 2022. From a general anti-cancer treatment to antioxidant or deer osteoporosis: The consequences of antler as the fastest-growing tissue. Anim. Prod. Sci., 10.1071/AN22176.
    CrossRef  |  Direct Link  |  
  4. von Stülpnagel, C., A. van Baalen, I. Borggraefe, K. Eschermann and T. Hartlieb et al., 2021. Network for therapy in rare epilepsies (NETRE): Lessons from the past 15 years. Front. Neurol., Vol. 11. 10.3389/fneur.2020.622510.
    CrossRef  |  Direct Link  |  
  5. Ontañón, J., J. Blas, C. de Cabo, C. Santos and E. Ruiz-Escribano et al., 2021. Influence of past infection with SARS-CoV-2 on the response to the biotech/pfizer bnt162b2 mRNA vaccine in health care workers: kinetics and durability of the humoral response. MedRxiv, Vol. 2021. 10.1101/2021.05.25.21257788.
    CrossRef  |  Direct Link  |  
  6. Ontañón, J., J. Blas, C. de Cabo, C. Santos and E. Ruiz-Escribano et al., 2021. Influence of past infection with SARS-CoV-2 on the response to the BNT162b2 mRNA vaccine in health care workers: kinetics and durability of the humoral immune response. EBioMedicine, Vol. 73. 10.1016/j.ebiom.2021.103656.
    CrossRef  |  Direct Link  |  
  7. Chonco, L., T. Landete-Castillejos, G. Serrano-Heras, M.P. Serrano and F.J. Pu00e9rez-Barberu00eda et al., 2021. Anti-tumour activity of deer growing antlers and its potential applications in the treatment of malignant gliomas. Sci. Rep., 10.1038/s41598-020-79779-w.
    CrossRef  |  Direct Link  |  
  8. Camara, C., D. Lozano-Ojalvo, E. Lopez-Granados, E. Paz-Artal and M. Pion et al., 2021. Differential effects of the second SARS-CoV-2 mRNA vaccine dose on t cell immunity in naïve and COVID-19 recovered individuals. BioRxiv, 10.1101/2021.03.22.436441.
    CrossRef  |  Direct Link  |  
  9. Pozo, J.S.G.D., C.De. Cabo and J. Solera, 2020. Gastrointestinal manifestations in satoyoshi syndrome: a systematic review. Orphanet. J. Rare Dis., 10.1186/s13023-020-01395-8.
    CrossRef  |  Direct Link  |  
  10. Sánchez-Larsen, A. and C. de Cabo, 2019. Seronegative limbic encephalitis. Neurol. Sci. 10.1007/s10072-019-04011-1.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Del Pozo, J.S.G., C. de Cabo and J. Solera, 2019. Treatment of Satoyoshi syndrome: A systematic review. Orphanet. J. Rare Dis., Vol. 14. 10.1186/s13023-019-1120-7.
    CrossRef  |  PubMed  |  Direct Link  |  
  12. Pardal-Fernández, J.M., M.C. Carrascosa-Romero, S. Álvarez, M.C. Medina-Monzón, M.B. Caamaño and C. de Cabo, 2018. A new severe mutation in the SLC5A7 gene related to congenital myasthenic syndrome type 20. Neuromuscular Disord., 28: 881-884.
    CrossRef  |  PubMed  |  Direct Link  |  
  13. Solera, J, S. Álvarez, J. Botet and C. de Cabo, 2017. A newly homozygous variant in ZNF808: A possible candidate gene for Satoyoshi Syndrome? J. Neurol. Sci., 379: 226-228.
    CrossRef  |  
  14. Prieto-Martin, A.I., J.D. Aroca-Aguilar, F. Sanchez-Sanchez, L.J. Munoz, D.E. Lopez, J. Escribano and C. de Cabo, 2017. Molecular and neurochemical substrates of the audiogenic seizure strains: The GASH: Sal model. Epilepsy Behav., 71B: 218-225.
    CrossRef  |  Direct Link  |  
  15. De Cabo, C., 2017. From nephron to neuron: An exciting journey in search of a cure for epilepsy. Curr Neurobiol., 7: 81-82.
    CrossRef  |  Direct Link  |  
  16. Carrascosa-Romero, M.C. and C.D.L.V. Cabo-De, 2017. The Genetic and Epigenetic Basis Involved in the Pathophysiology of ASD: Therapeutic Implications. In: Paradigms, Recent Research and Clinical Applications, Fitzgerald, M., (Eds.,), InTech UK 1.
    CrossRef  |  Direct Link  |  
  17. Solera, J., C. de Cabo and S.G.J. del Pozo, 2016. Effectiveness of fluticasone furoate-vilanterol in COPD. N Engl. J. Med., 375: 2606-2607.
    CrossRef  |  
  18. Grande-Martín, A., J.M. Pardal-Fernández, M.C. Carrascosa-Romero and C. De Cabo, 2016. Tonic seizure status epilepticus triggered by valproate in a child with doose syndrome. Neuropediatrics, 47: 187-189.
    CrossRef  |  
  19. Carrascosa-Romero, M.C. and C.D.C.D.L. Vega, 2016. GABAergic interneurons in severe early epileptic encephalopathy with a suppression-burst pattern: A continuum of pathology. Asian J. Res. Botany, 4: 38-52.
    CrossRef  |  Direct Link  |  
  20. Solera, J., B. Rallo, A.S. Herranz, J.M. Pardal, R.M.D. Rio and C. de Cabo, 2015. High glycine levels in the cerebrospinal fluid in Satoyoshi syndrome. J. Neurol. Sci., 357: 312-313.
    CrossRef  |  PubMed  |  Direct Link  |  
  21. Carrascosa-Romero, M.C. and C.C. Vega, 2015. The Comorbidity of ADHD and Autism Spectrum Disorders (ASDs) in Community Pre-Schoolers. In: ADHD-New Directions in Diagnosis and Treatment. Norvilitis, J.M. (Ed.). InTech-Open Access Publisher, Croatia., ISBN: 978-953-51-2166-4, pp: 109-164..
    CrossRef  |  Direct Link  |  
  22. Pardal-Fernandez, J.M., E. Palazon-Garcia, F. Hernandez-Fernandez and C. de Cabo, 2014. Contribution of a new electrophysiologic test to Morton's neuroma diagnosis. Foot Ankle Surgery, 20: 109-114.
    CrossRef  |  Direct Link  |  
  23. Carrascosa-Romero, M.C. and C. de Cabo-de La Vega, 2014. Neuroprotection in Perinatal Hypoxic-Ischemic Encephalopathy-Pharmacologic Combination Therapy. In: Cerebral Palsy-Challenges for the Future, Svraka, E. (Ed.). InTecH, USA., ISBN: 978-953-51-1234-1, PP: 123-192.
  24. Carballosa-Gonzalez, M.M., L.J. Munoz, T. Lopez-Alburquerque, J.M. Pardal-Fernandez and E. Nava et al., 2013. EEG characterization of audiogenic seizures in the hamster strain GASH: Sal. Epilepsy Res., 106: 318-325.
    CrossRef  |  
  25. Prieto-Martin, A., S. Llorens, J.M. Pardal-Fernandez, L. Munoz and D.E. Lopez et al., 2012. Opposite caudal versus rostral brain nitric oxide synthase response to generalized seizures in a novel rodent model of reflex epilepsy. Life Sci., 90: 531-537.
    CrossRef  |  
  26. Carrascosa-Romero, M.C. and C. de Cabo, 2012. Titulo: Neurocristopathies: Role of Glial Cells, Genetic Basis and Relevance of Brain Imaging for Diagnosis. In: Neuroimaging-Clinical Applications, Bright, P. (Ed.). InTech-Open Access Publisher, USA., pp: 109-128.
  27. Carrascosa-Romero, M.C., J.L. Guerrero Solano and C. de Cabo, 2011. Ciliopathies: Primary Cilia and Signaling Pathways in Mammalian Development. In: Neuroimaging for Clinicians-Combining Research and Practice, Peres, J. (Ed.). InTech-Open Access Publisher, USA., pp: 125-144.
  28. Pardal-Fernandez, J.M., M.C. Carrascosa-Romero, C. de Cabo-De la Vega, I. Iniesta-Lopez, E. Gil-Pons and A. Martinez-Gutierrez, 2009. Atypical glycine encephalopathy in an extremely low birth weight infant: Description of a new mutation and clinical and electroencephalographic analysis. Epileptic Disorders, 11: 48-53.
    CrossRef  |  
  29. Lujan, R., C. de Cabo and J.M. Juiz, 2008. Inhibitory synaptogenesis in the rat anteroventral cochlear nucleus. Neuroscience, 154: 315-328.
    CrossRef  |  
  30. Llorens, S., R.M. Melero-Fernandez, A. Pascual, A. Prieto, Y. Mendizabal, C. de Cabo, E. Nava and J. Jordan, 2007. The senescence-accelerated mouse (SAM-P8) as a model for the study of vascular functional alterations during aging. Biogerontology, 8: 663-672.
    PubMed  |  
  31. Jordan, J., C. de Cabo, R. Insausti, M.M. Arroyo and M.F. Galindo, 2006. 100 years of research in Alzheimer's disease: Past, present and future. Rev. Afa Albacete, 15: 4-5.
  32. De Cabo-de la Vega, C., P. Villanueva-Hernandez and A. Prieto-Martin, 2006. Neurochemistry of epilepsy, inhibitory neurotransmission and experimental models: New perspectives. Rev. Neurol., 42: 159-168.
    Direct Link  |  
  33. De Cabo-de la Vega, C., P. Villanueva-Hernandez and A. Prieto-Martin, 2006. Kainate glutamate receptor type and epilepsy. Replica. Rev. Neurol., 43: 382-382.
  34. Poblet, E., F. Jimenez, C. de Cabo, A. Prieto Martin and R. Sanchez-Prieto, 2005. The calciumbinding protein calretinin is a marker of the companion cell layer of the human hair follicle. Br. J. Dermatol., 152: 1316-1320.
    CrossRef  |  
  35. Lujan, R., C. de Cabo de la Vega, E. Dominguez del Toro, J.J. Ballesta, M. Criado and J.M. Juiz, 2003. Immunohistochemical localization of the voltage-gated potassium channel subunit Kv1.4 in the central nervous system of the adult rat. J. Chem. Neuroanat, 26: 209-224.
    CrossRef  |  
  36. Campos, M.L., C. De Cabo, W. Wisden, J.M. Juiz and D. Merlo, 2001. Expression GABAA receptor subunits in the rat brainstem auditory pathways: Cochlear nuclei, superior olivary complex and nucleus of the lateral lemniscus. Neuroscience, 102: 625-638.
    CrossRef  |  
  37. Desousa, N.J., G.R. Wunderlich, C. de Cabo and F.J. Vaccarino, 1999. The expression of behavioral sensitization to amphetamine: Role of CCKA-receptors. Pharmacol. Biochem. Behav., 62: 31-37.
  38. Lanca, A.J., C. de Cabo, A.I. Arifuzzaman and F.J. Vaccarino, 1998. Cholecystokinergic innervation of nucleus accumbens subregions. Peptides, 19: 859-868.
    CrossRef  |  
  39. Juiz, J.M., M.E. Rubio, M.L. Campos and C. de Cabo, 1998. Cytomolecular Foundations of Signal Processing in the Dorsal Cochlear Nucleus. In: Psychophysical and Physiological Advances in Hearing, Palmer, A.R., A. Rees, A.Q. Summerfield and R. Meddis (Eds.). Whurr Publishers, London, pp: 204-212.
  40. Desousa, N.J., G.R. Wunderlich, C. de Cabo and F.J. Vaccarino, 1998. Individual differences in sucrose intake predict behavioral reactivity in rodent models of anxiety. Pharmacol. Biochem. Behav., 60: 841-846.
    CrossRef  |  
  41. De Cabo, C. and M.P. Viveros, 1997. Effects of neonatal naltrexone on neurological and somatic development in rats of both genders. Neurotoxicol. Teratol., 19: 499-509.
    CrossRef  |  
  42. Viveros, M.P., C. de Cabo, M.I. Colado and M.I. Martin, 1995. Naltrexone administration during the preweanling period affects striatal and hypothalamic serotonergic systems, but not midbrain serotonergic or striatal dopaminergic systems in the adult rat. Neurosci. Lett., 201: 195-198.
    CrossRef  |  
  43. Kitchen, I., M.D.W. Kelly and C. de Cabo, 1995. K-and 8-opioid recep-tor mediated antinociception in prewealing rats. Analgesia, 1: 512-515.
  44. De Cabo de la Vega, C., A. Pujol and M.P. Viveros, 1995. Neonatally administered naltrexone affects several behavioural responses in adult rats of both genders. Pharmacol. Biochem. Behav., 50: 277-286.
    CrossRef  |  
  45. Viveros, M.P., A. Pujol, C. de Cabo and M.I. Martin, 1993. A study on the development of nociceptive responses in pre- and postweanling rats: The tail electric stimulation test as a suitable methodology. Methods Findings Exp. Clin. Pharmacol., 15: 31-33.
  46. Pujol, A., C. de Cabo, M.I. Martin and M.P. Viveros, 1993. A developmental study on stressinduced-antinociception measured by the tail electric stimulation test. Pharmacol. Biochem. Behav., 46: 373-376.
    PubMed  |  
  47. De Cabo, C., M.I. Martin and M.P. Viveros, 1993. Preliminary evidence of opioid stressinduced antinociception using a novel procedure of forced swimming in the rat. Cepnesp Bull., 1: 19-22.
  48. De Cabo, C., M.I. Colado, A. Pujol, M.I. Martin and M.P. Viveros, 1993. Naltrexone administration effects on brain monoamines in developing rats. Brain Res. Bull., 34: 395-406.
  49. De Cabo, C., I. Kitchen, M. Kelly and M.P. Viveros, 1993. Effects of !b-funaltrexamine treatment and sexual isolation in the perinatal period on the development of !u-opioid receptors and nociception. Psychoneuroendocrinology, 18: 415-424.
    CrossRef  |  
  50. De Cabo, C., M. Kelly, I. Kitchen and P. Viveros, 1992. Effects of neonatal sexual isolation on μ-receptor development and nociceptive responses in the rat. Neurosci. Res. Commun., 10: 79-86.
  51. De Cabo, C., I. Kitchen and M.P. Viveros, 1992. Adaptation of nociceptive procedures to developing animals. Sci. Techniques Anim. Laboratoire, 17: 145-148.