Area of Interest:

Biomedical Sciences

100%

Pharmacology

62%

Cell Biology

90%

Biochemistry

75%

Toxicity

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
68

Abstracts
1

Selected Publications

Napolitano, L., M. Galluccio, M. Scalise, C. Parravicini, L. Palazzolo, I. Eberini and C. Indiveri, 2017. Novel Insights into the Transport Mechanism of the human amino acid transporter LAT1 (SLC7A5). Probing critical residues for substrate translocation. Biochim. Biophys. Acta (BBA) Gen. Subj., .
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Tarlungeanu, D.C., E. Deliu, C.P. Dotter, M. Kara and P.C. Janiesch, et al., 2016. Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder. Cell, 167: 1481-1494.
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Scalise, M., L. Pochini, M. Galluccio and C. Indiveri, 2016. Glutamine transport. From energy supply to sensing and beyond. Biochim. Biophys. Acta, 1857: 1147-1157.
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Pochini, L., M. Scalise, S. Di Silvestre, S. Belviso and A. Pandolfi, et al., 2016. Acetylcholine and acetylcarnitine transport in peritoneum: Role of the SLC22A4 (OCTN1) transporter. Biochim. Biophys. Acta (BBA) Biomembr., 1858: 653-660.
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Tonazzi, A., N. Giangregorio, L. Console, M. Scalise and D. La Russa, et al., 2015. Mitochondrial carnitine/acylcarnitine transporter, a novel target of mercury toxicity. Chem. Res. Toxicol., 28: 1015-1022.
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Scalise, M., L. Pochini, P. Pingitore, K. Hedfalk and C. Indiveri, 2015. Cysteine is not a substrate but a specific modulator of human ASCT2 (SLC1A5) transporter. FEBS Lett., 589: 3617-3623.
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Pochini, L., M. Scalise and C. Indiveri, 2015. Immuno-detection of OCTN1 (SLC22A4) in HeLa cells and characterization of transport function. Int. Immunopharmacol., 29: 21-26.
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Napolitano, L., M. Scalise, M. Galluccio, L. Pochini, L.M. Albanese and C. Indiveri, 2015. LAT1 is the transport competent unit of the LAT1/CD98 heterodimeric amino acid transporter. Int. J. Biochem. Cell Biol., 67: 25-33.
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Console, L., M. Scalise, Z. Tarmakova, I.R. Coe and C. Indiveri, 2015. N-linked glycosylation of human SLC1A5 (ASCT2) transporter is critical for trafficking to membrane. Biochim. Biophys. Acta (BBA) Mol. Cell Res., 1853: 1636-1645.
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Scalise, M., L. Pochini, S. Panni, P. Pingitore, K. Hedfalk and C. Indiveri, 2014. Transport mechanism and regulatory properties of the human amino acid transporter ASCT2 (SLC1A5). Amino Acids, 46: 2463-2475.
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Scalise, M., L. Pochini, M. Galluccio and C. Indiveri, 2014. Amino acid transporters in drug discovery. Curr. Res. Drug Discovery, 1: 1-16.
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Pochini, L., M. Scalise, M. Galluccio and C. Indiveri, 2014. Membrane transporters for the special amino acid glutamine: structure/function relationships and relevance to human health. Front. Chem., .
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Pochini, L., A. Seidita, C. Sensi, M. Scalise, I. Eberini and C. Indiveri, 2014. Nimesulide binding site in the B0AT1 (SLC6A19) amino acid transporter. Mechanism of inhibition revealed by proteoliposome transport assay and molecular modelling. Biochem. Pharmacol., 89: 422-430.
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Galluccio, M., L. Pochini, V. Peta, M. Ianni, M. Scalise and C. Indiveri, 2014. Functional and molecular effects of mercury compounds on the human OCTN1 cation transporter. C50 and C136 are the targets for potent inhibition. Toxicol. Sci., 144: 105-113.
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Scalise, M., L. Pochini, N. Giangregorio, A. Tonazzi and C. Indiveri, 2013. Proteoliposomes as tool for assaying membrane transporter functions and interactions with xenobiotics. Pharmaceutics, 5: 472-497.
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Pochini, L., M. Scalise, M. Galluccio and C. Indiveri, 2013. OCTN cation transporters in health and disease: role as drug targets and assay development. J. Biomol. Screening, 18: 851-867.
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Pingitore, P., L. Pochini, M. Scalise, M. Galluccio, K. Hedfalk and C. Indiveri, 2013. Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris-Functional and kinetic asymmetry revealed in proteoliposomes. Biochim. Biophys. Acta (BBA) Biomembr., 1828: 2238-2246.
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Indiveri, C., M. Galluccio, M. Scalise and L. Pochini, 2013. Strategies of bacterial over expression of membrane transporters relevant in human health: the successful case of the three members of OCTN subfamily. Mol. Biotechnol., 54: 724-736.
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Galluccio, M., P. Pingitore, M. Scalise and C. Indiveri, 2013. Cloning, large scale over-expression in E. coli and purification of the components of the human LAT 1 (SLC7A5) amino acid transporter. Protein J., 32: 442-448.
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Scalise, M., M. Galluccio, R. Accardi, I. Cornet, M. Tommasino and C. Indiveri, 2012. Human OCTN2 (SLC22A5) is down-regulated in virus and nonvirus-mediated cancer. Cell Biochem. Funct., 30: 419-425.
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Scalise, M., M. Galluccio, L. Pochini and C. Indiveri, 2012. Over-expression in Escherichia coli, purification and reconstitution in liposomes of the third member of the OCTN sub-family: The mouse carnitine transporter OCTN3. Biochem. Biophys. Res. Commun., 422: 59-63.
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Pochini, L., M. Scalise, M. Galluccio, G. Pani, K.A. Siminovitch and C. Indiveri, 2012. The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn`s disease. Biochim. Biophys. Acta (BBA) Biomembr., 1818: 559-565.
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Pochini, L., M. Scalise, M. Galluccio and C. Indiveri, 2012. Regulation by physiological cations of acetylcholine transport mediated by human OCTN1 (SLC22A4). Implications in the non-neuronal cholinergic system. Life Sci., 91: 1013-1016.
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Galluccio, M., L. Amelio, M. Scalise, L. Pochini, E. Boles and C. Indiveri, 2012. Over-expression in E. coli and purification of the human OCTN2 transport protein. Mol. Biotechnol., 50: 1-7.
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Pochini, L., M. Scalise, M. Galluccio, L. Amelio and C. Indiveri, 2011. Reconstitution in liposomes of the functionally active human OCTN1 (SLC22A4) transporter overexpressed in Escherichia coli. Biochem. J., 439: 227-233.
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Accardi, R., R. Rubino, M. Scalise, T. Gheit and N. Shahzad, et al., 2011. E6 and E7 from human papillomavirus type 16 cooperate to target the PDZ protein Na/H exchange regulatory factor 1. J. Virol., 85: 8208-8216.
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Accardi, R., M. Scalise, T. Gheit, I. Hussain and J. Yue, et al., 2011. IκB kinase β promotes cell survival by antagonizing p53 functions through ΔNp73α phosphorylation and stabilization. Mol. Cell. Biol., 31: 2210-2226.
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Pochini, L., M. Scalise and C. Indiveri, 2009. Inactivation by omeprazole of the carnitine transporter (OCTN2) reconstituted in liposomes. Chem. Biol. Interact., 179: 394-401.
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