Dr. Adriano  Mollica
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Dr. Adriano Mollica

Associate Professor
Gabriele d Annunzio University of Chieti-Pescara, Italy


Highest Degree
Ph.D. in Pharmaceutical Sciences from University of Arizona, USA

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Area of Interest:

Molecular Sciences
100%
Chemotactic Peptides
62%
Peptide Chemistry
90%
Opioid Agonist
75%
Nutraceuticals
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Zengin, G., R. Ceylan, J. Katanić, A. Mollica and A, Aktumsek et al., 2017. Combining in vitro, in vivo and in silico approaches to evaluate nutraceutical potentials and chemical fingerprints of Moltkia aurea and Moltkia coerulea. Food Chem. Toxicol., 107: 540-553.
    CrossRef  |  PubMed  |  Direct Link  |  
  2. Zengin, G., G. Bulut, A. Mollica, M.Z. Haznedaroglu and A. Dogan et al., 2017. Bioactivities of Achillea phrygia and Bupleurum croceum based on the composition of phenolic compounds: In vitro and in silico approaches. Food Chem. Toxicol., 107: 597-608.
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Zengin, G., A. Uysal, A. Aktumsek, A. Mocan and A. Mollica et al., 2017. Euphorbia denticulata Lam.: A promising source of phyto-pharmaceuticals for the development of novel functional formulations. Biomedicine and Pharmacotherapy, 87: 27-36.
    CrossRef  |  Direct Link  |  
  4. Zengin, G., A. Mollica, A. Aktumsek, C. Marie Nancy Picot, M. Fawzi Mahomoodally, 2017. In vitro and in silico insights of Cupressus sempervirens, Artemisia absinthium and Lippia triphylla: Bridging traditional knowledge and scientific validation. Eur. J. Integrative Medi., 12: 135-141.
    CrossRef  |  Direct Link  |  
  5. Travaglini, L., C. Giordano, A. D'Annibale, M. Gubitosi and M.C. di Gregorio et al., 2017. Twisted nanoribbons from a RGD-bearing cholic acid derivative. Colloids and Surfaces B: Biointerfaces, 159: 183-190.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Stefanucci, A., W. Lei, V.J. Hruby, G. Macedonio and G. Luisi et al., 2017. Fluorescent-labeled bioconjugates of the opioid peptides biphalin and DPDPE incorporating fluorescein-maleimide linkers. Future Med. Chem., 9: 859-869.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Stefanucci, A., E. Novellino, S. Mirzaie, G. Macedonio and S. Pieretti et al., 2017. Opioid Receptor Activity and Analgesic Potency of DPDPE Peptide Analogues Containing a Xylene Bridge. ACS Med. Chem. Letters, 8: 449 -454.
    CrossRef  |  PubMed  |  Direct Link  |  
  8. Stefanucci, A., A. Carotenuto, G. Macedonio, E. Novellino and S. Pieretti et al., 2017. Cyclic Biphalin Analogues Incorporating a Xylene Bridge: Synthesis, Characterization, and Biological Profile. ACS Medi. Chem. Letters 8: 858-863.
    CrossRef  |  PubMed  |  Direct Link  |  
  9. Rodrigues, M.J., K.N. Gangadhar, G. Zengin, A. Mollica and J.Varela et al., 2017. Juncaceae species as sources of innovative bioactive compounds for the food industry: In vitro antioxidant activity, neuroprotective properties and in silico studies. Food Chem. Toxicol., 107: 590-596.
    CrossRef  |  PubMed  |  Direct Link  |  
  10. Nescatelli, R., S. Carradori, F. Marini, V. Caponigro, R. Bucci and C. De Monte et al., 2017. Geographical characterization by MAE-HPLC and NIR methodologies and carbonic anhydrase inhibition of Saffron components. Food Chem., 221: 855-863.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Mollica, A., S. Pelliccia, V. Famiglini, A. Stefanucci and G. Macedonio et al., 2017. Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors. J. Enzyme Inhib. Med. Chem., 32: 444-451.
    CrossRef  |  PubMed  |  Direct Link  |  
  12. Mollica, A., G. Zengin, M. Locatelli, A. Stefanucci and G. Macedonio et al., 2017. An assessment of the nutraceutical potential of Juglans regia L. leaf powder in diabetic rats. Food Chem. Toxicol., 107: 554-564.
    CrossRef  |  PubMed  |  Direct Link  |  
  13. Mollica, A., G. Zengin, M. Locatelli, A. Stefanucci and A. Mocan et al., 2017. Anti-diabetic and anti-hyperlipidemic properties of Capparis spinosa L.:In vivo and in vitro evaluation of its nutraceutical potential. J. Functional Foods, 35: 32-42.
    CrossRef  |  Direct Link  |  
  14. Mocan, A., G. Zengin, M. Simirgiotis, M. Schafberg and A. Mollica et al., 2017. Functional constituents of wild and cultivated Goji (L. barbarum L.) leaves: phytochemical characterization, biological profile, and computational studies. J. Enzyme Inhib. Med. Chem., 3: 153-168.
    CrossRef  |  PubMed  |  Direct Link  |  
  15. Maccallini, C., A. Mollica and R. Amoroso, 2017. The Positive Regulation of eNOS Signaling by PPAR Agonists in Cardiovascular Diseases. American J. Cardiovascular Drugs 17: 273-281.
    CrossRef  |  PubMed  |  Direct Link  |  
  16. D'Ascenzio, M., P. Guglielmi, S. Carradori, D. Secci and R. Florio, A. Mollica et al., 2017. Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms. J. Enzyme Inhib. Med. Chem., 32: 51-59.
    CrossRef  |  PubMed  |  Direct Link  |  
  17. Uysal, A., G. Zengin, A. Mollica, E. Gunes and M. Locatelliet al., 2016. Chemical and biological insights on Cotoneaster integerrimus: A new (-)- epicatechin source for food and medicinal applications. Phytomedicine, 23: 979-988.
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  18. Stefanucci, A., R. Costante, G. Macedonio, S. Dvoracsko, A. Mollica, 2016. Cysteine-, methionine- and seleno-cysteine-proline chimeras: Synthesis and their use in peptidomimetics design. Curr. Bioact. Compd., 12: 200-206.
    CrossRef  |  Direct Link  |  
  19. Secci, D., S. Carradori, B. Bizzarri, P. Chimenti and C. De Monte et al., 2016. Novel 1,3-thiazolidin-4-one derivatives as promising anti- Candida agents endowed with anti-oxidant and chelating properties. Eur. J. Med. Chem., 117: 144-156.
    CrossRef  |  PubMed  |  Direct Link  |  
  20. Monti, L., A. Stefanucci, S. Pieretti, F. Marzoli and L.Fidanza et al., 2016. Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates. J. Enzyme Inhib. Chem., 31: 1638-1647.
    CrossRef  |  PubMed  |  Direct Link  |  
  21. Mollica, A., S. Mirzaie, R. Costante, S. Carradori and G. Macedonioet al., 2016. Exploring the biological consequences of conformational changes in aspartame models containing constrained analogues of phenylalanine. J. Enzyme Inhib. Med. Chem., 31: 953-963.
    CrossRef  |  PubMed  |  Direct Link  |  
  22. Mollica, A., R. Costante, S. Mirzaie, S. Carradori and G. Macedonio et al., 2016. Preparation of Constrained Unnatural Aromatic Amino Acids via Unsaturated Diketopiperazine Intermediate. J. Heterocyclic Chem., 53: 2106-2110.
    CrossRef  |  Direct Link  |  
  23. Mollica, A., M. Locatelli, G. Macedonio, S. Carradori and A.P. Sobolev et al., 2016. Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars. J. Enzyme Inhib. Med. Chem., 31: 1-6.
    CrossRef  |  PubMed  |  Direct Link  |  
  24. Mollica, A. and G. Zengin, 2016. Threonine-proline-chimeras, a valuable building block for peptidomimetic design: A review. Curr. Bioact. Compd., 12: 221-228.
    CrossRef  |  Direct Link  |  
  25. Mocan, A., G. Zengin, G. Crişan and A. Mollica, 2016. Enzymatic assays and molecular modeling studies of Schisandra chinensis lignans and phenolics from fruit and leaf extracts. J. Enzyme Inhib. Med. Chem., 31: 200-210.
    CrossRef  |  PubMed  |  Direct Link  |  
  26. Mocan, A., G. Zengin, A. Uysal, E. Gunes and A. Mollicaet al., 2016. Biological and chemical insights of Morina persica L.: A source of bioactive compounds with multifunctional properties. J. Functional Foods, 25: 94-109.
    CrossRef  |  Direct Link  |  
  27. Macedonio, G., A. Stefanucci, C. Maccallini, S. Mirzaie and E. Novellino et al., 2016. Hemopressin peptides as modulators of the endocannabinoid system and their potential applications as therapeutic tools. Protein and Peptide Letters, 23: 1045-1051.
    PubMed  |  Direct Link  |  
  28. Luisi, G., A. Mollica, S. Carradori, A. Lenoci and A. De Luca et al., 2016. Nitrobenzoxadiazole-based GSTP1-1 inhibitors containing the full peptidyl moiety of (pseudo)glutathione. J. Enzyme Inhib. Med. Chem., 31: 924-930.
    CrossRef  |  PubMed  |  Direct Link  |  
  29. Hosseini, Y., A. Mollica and S. Mirzaie, 2016. Structure-based virtual screening efforts against HIV-1 reverse transcriptase to introduce the new potent non-nucleoside reverse transcriptase inhibitor. J. Mol. Struct., 1125: 592-600.
    CrossRef  |  Direct Link  |  
  30. Gidaro, M.C., S. Alcaro, D. Secci, D. Rivanera and A. Mollica et al., 2016. Identification of new anti-Candida compounds by ligand-based pharmacophore virtual screening. J. Enzyme Inhib. Med. Chem., 31: 1703-1706.
    CrossRef  |  PubMed  |  Direct Link  |  
  31. Fantacuzzi, M., C. Maccallini, M. Di Matteo, A. Ammazzalorso and I. et al., 2016. Screening of NOS activity and selectivity of newly synthesized acetamidines using RP-HPLC. J. Pharmaceutical and Biomed. Analysis, 120: 419-424.
    CrossRef  |  PubMed  |  Direct Link  |  
  32. De Monte, C., S. Carradori, B. Bizzarri, A. Bolasco and F. Caprara et al., 2016. Anti-Candida activity and cytotoxicity of a large library of new N-substituted-1,3-thiazolidin-4-one derivatives. Eur. J. Med. Chem., 107: 82-96.
    CrossRef  |  PubMed  |  Direct Link  |  
  33. Carradori, S., D. Secci, C. De Monte, A. Mollica and M. Ceruso et al., 2016. A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms. Bioorganic and Med. Chem., 24: 1095-1105.
    CrossRef  |  PubMed  |  Direct Link  |  
  34. Stefanucci, A., R. Costante, S. Carradori, E. Novellino, A. Mollica, 2015. Synthetic strategies for aspartic and glutamic acid-proline chimeras: A review. Mini-Reviews in Org. Chem., 12: 216-236.
    CrossRef  |  Direct Link  |  
  35. Stefanucci, A., J. Mosquera, E. VÌzquez, J.L. MascareÜas and E. Novellino et al., 2015. Synthesis, Characterization, and DNA Binding Profile of a Macrocyclic β-Sheet Analogue of ARC Protein. ACS Med. Chem. Lett., 16: 1220-1224.
    CrossRef  |  Direct Link  |  
  36. Mollica, A., R. Costante, E. Novellino, A. Stefanucci and S.Pieretti et al., 2015. Design, Synthesis and Biological Evaluation of Two Opioid Agonist and Cav2.2 Blocker Multitarget Ligands. Chem. Bio. Drug Des., 86: 156-162.
    CrossRef  |  Direct Link  |  
  37. Mollica, A., R. Costante, A. Stefanucci and E. Novellino, 2015. Cyclotides: A natural combinatorial peptide library or a bioactive sequence player? J. Enzyme Inhib. Medi. Chem., 30: 575-580.
    CrossRef  |  PubMed  |  Direct Link  |  
  38. Mollica, A., R. Costante, A. Akdemir, S. Carradori and A. Stefanucci et al., 2015. Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies. Bioorg. Med. Chem., 23: 5311-5318.
    CrossRef  |  PubMed  |  Direct Link  |  
  39. Mollica, A., A. Stefanucci, R. Costante and V.J. Hruby, 2015. Rational approach to the design of bioactive peptidomimetics: Recent developments in opioid agonist peptides. Stud. Nat. Prod. Chem., 46: 27-68.
    CrossRef  |  
  40. Dvoracsko, S., A. Stefanucci, E. Novellino, A. Mollica, 2015. The design of multitarget ligands for chronic and neuropathic pain. Future Med. Chem., 7: 2469-2483.
    CrossRef  |  PubMed  |  Direct Link  |  
  41. De Monte, C., S. Carradori, D. Secci, M. D'Ascenzio and P. Guglielmi et al., 2015. Synthesis and pharmacological screening of a large library of 1,3,4-thiadiazolines as innovative therapeutic tools for the treatment of prostate cancer and melanoma. Eur. J. Med. Chem., 105: 245-262.
    CrossRef  |  PubMed  |  Direct Link  |  
  42. De Monte, C., S. Carradori, A. Gentili, A. Mollica, D. Trisciuoglio and C.T. Supuran, 2015. Dual cyclooxygenase and carbonic anhydrase inhibition by nonsteroidal anti-inflammatory drugs for the treatment of cancer. Curr. Med. Chem., 22: 2812-2818.
    PubMed  |  Direct Link  |  
  43. De Monte, C., B. Bizzarri, M.C. Gidaro, S. Carradori and A. Mollica et al., 2015. Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents. J. Enzyme Inhib. Med. Chem., 30: 1027-1033.
    CrossRef  |  PubMed  |  Direct Link  |  
  44. Costante, R., A. Stefanucci, S. Carradori, E. Novellino and A. Mollica, 2015. DPP-4 inhibitors: A patent review (2012 - 2014) Expert Opinion on Therapeutic Patents, 25: 209-236.
    CrossRef  |  PubMed  |  Direct Link  |  
  45. Carradori, S., A. Mollica, C. De Monte, A. Granese and C.T. Supuran, 2015. Nitric oxide donors and selective carbonic anhydrase inhibitors: A dual pharmacological approach for the treatment of glaucoma, cancer and osteoporosis. Molecules, 20: 5667-5679.
    CrossRef  |  Direct Link  |  
  46. Stefanucci, A., E. Novellino, R. Costante and A. Mollica, 2014. Pyroglutamic acid derivatives: Building blocks for drug discovery. Heterocycles, 89: 1801-1825.
    CrossRef  |  Direct Link  |  
  47. Mollica, A., R. Costante, S. Fiorito, S. Genovese and A. Stefanucci et al., 2014. Synthesis and anti-cancer activity of naturally occurring 2,5-diketopiperazines. Fitoterapia, 98: 91-97.
    CrossRef  |  Direct Link  |  
  48. Mollica, A., A. Carotenuto, E. Novellino, A. Limatola and R. Costante et al., 2014. Novel cyclic biphalin analogue with improved antinociceptive properties. ACS Med. Chem. Letters, 5: 1032-1036.
    CrossRef  |  Direct Link  |  
  49. Costante, R., F. Pinnen, A. Stefanucci and A.Mollica, 2014. Potent biphalin analogs with μ/δ mixed opioid activity:In vivo and in vitro biological evaluation. Archiv der Pharmazie, 347: 305-312.
    CrossRef  |  Direct Link  |  
  50. Mollica, A., R. Costante, A. Stefanucci, F. Pinnen, G. Lucente, S. Fidanza and S. Pieretti, 2013. Antinociceptive profile of potent opioid peptide AM94, a fluorinated analogue of biphalin with non-hydrazine linker. J. Peptide Sci., 19: 233-239.
    CrossRef  |  PubMed  |  Direct Link  |  
  51. Mollica, A., R. Costante, A. Stefanucci, F. Pinnen and G. Luisi et al., 2013. Hybrid peptides endomophin-2/DAMGO: Design, synthesis and biological evaluation. Eur. J. Med. Chem., 68: 167-177.
    CrossRef  |  PubMed  |  Direct Link  |  
  52. Mollica, A., F. Pinnen, R. Costante, M. Locatelli and A. Stefanucci et al., 2013. Biological active analogues of the opioid peptide biphalin: Mixed α/β3-peptides. J. Med. Chem., 56: 3419-3423.
    CrossRef  |  Direct Link  |  
  53. Mollica, A., F. Pinnen, A. Stefanucci and R. Costante, 2013. The evolution of peptide synthesis: From early days to small molecular machines. Curr. Bioact. Compd., 9: 184-202.
    CrossRef  |  Direct Link  |  
  54. Mollica, A., A. Stefanucci and R. Costante, 2013. Strategies for developing tuberculosis vaccines: Emerging approaches. Curr. Drug Targets, 14: 938-951.
    PubMed  |  Direct Link  |  
  55. Feliciani, F., F. Pinnen, A. Stefanucci, R. Costante, I. Cacciatore, G. Lucente and A. Mollica, 2013. Structure-activity relationships of biphalin analogs and their biological evaluation on opioid receptors. Mini-Reviews in Med. Chem., 13: 11-33.
    PubMed  |  Direct Link  |  
  56. Brunetti, L., C. Ferrante, G. Orlando, L. Recinella and S. Leone et al., 2013. Orexigenic effects of endomorphin-2 (em-2) related to decreased crh gene expression and increased dopamine and norepinephrine activity in the hypothalamus. Peptides, 48: 83-88.
    CrossRef  |  PubMed  |  Direct Link  |  
  57. Pinnen, F., I. Cacciatore, C. Cornacchia, A. Mollica and P. Sozio et al., 2012. CNS delivery of L-dopa by a new hybrid glutathione-methionine peptidomimetic prodrug. Amino Acids, 42: 261-269.
    Direct Link  |  
  58. Mollica, A., S. Genovese, F. Pinnen, A. Stefanucci, M. Curini and F. Epifano, 2012. Ytterbium triflate catalysed Meerwein-Ponndorf-Verley (MPV) reduction. Tetrahedron Letters, 53: 890-892.
    CrossRef  |  Direct Link  |  
  59. Mollica, A., M. Locatelli, A. Stefanucci and F. Pinnen, 2012. Synthesis and bioactivity of secondary metabolites from marine sponges containing dibrominated indolic systems. Molecules, 17: 6083-6099.
    CrossRef  |  Direct Link  |  
  60. Mollica, A., F. Pinnen, A. Stefanucci, L. Mannina and A.P. Sobolev et al., 2012. Cis-4-amino-l-proline residue as a scaffold for the synthesis of cyclic and linear endomorphin-2 analogues: Part 2 J. Med. Chem., 55: 8477-8482.
    CrossRef  |  PubMed  |  Direct Link  |  
  61. Mollica, A., F. Pinnen, A. Stefanucci, F. Feliciani and C. Campestre et al., 2012. The cis-4-amino-l-proline residue as a scaffold for the synthesis of cyclic and linear endomorphin-2 analogues. J. Med. Chem., 55: 3027-3035.
    CrossRef  |  Direct Link  |  
  62. Mollica, A., F. Feliciani, A.Stefanucci, E.F. Fadeev and F. Pinnen, 2012. (Acyloxy)alkoxy moiety as amino acids protecting group for the synthesis of (R,R)-2,7 diaminosuberic acid via RCM. Protein and Peptide Letters, 19: 1245-1249.
    PubMed  |  Direct Link  |  
  63. Mollica, A., F. Feliciani, A. Stefanucci, R. Costante and G. Lucente et al., 2012. Synthesis and biological evaluation of new active For-Met-Leu-Phe-OMe analogues containing para-substituted Phe residues. J. Peptide Sci., 18: 418-426.
    CrossRef  |  PubMed  |  Direct Link  |  
  64. Mollica, A., A. Stefanucci, R. Costante and F. Pinnen, 2012. Role of formyl peptide receptors (FPR) in abnormal inflammation responses involved in neurodegenerative diseases. Anti-Inflammatory and Anti-Allergy Agents in Med. Chem., 11: 20-36.
    PubMed  |  Direct Link  |  
  65. Mollica, A., A. Stefanucci, F. Feliciani, I. Cacciatore, C. Cornacchia and F. Pinnen, 2012. Delivery methods of camptothecin and its hydrosoluble analogue irinotecan for treatment of colorectal cancer Curr. Drug Del., 9: 122-131.
    CrossRef  |  Direct Link  |  
  66. Locatelli, M., L. Governatori, G. Carlucci, S. Genovese, A. Mollica and F. Epifano, 2012. Recent application of analytical methods to phase I and phase II drugs development: A review Biomed. Chromatogr., 26: 283-300.
    CrossRef  |  Direct Link  |  
  67. Leone, S., A. Chiavaroli, G. Orlando, A. Mollica, C. Di Nisio, L. Brunetti and M. Vacca, 2012. The analgesic activity of biphalin and its analog AM 94 in rats. Eur. J. Pharmacology, 685: 70-73.
    CrossRef  |  PubMed  |  Direct Link  |  
  68. Cornacchia, C., I. Cacciatore, L. Baldassarre, A. Mollica, F. Feliciani and F. Pinnen, 2012. 2,5-Diketopiperazines as neuroprotective agents. Mini-Reviews in Med. Chem., 12: 2-12.
    CrossRef  |  Direct Link  |  
  69. Cacciatore, I., C. Cornacchia, L. Baldassarre, E. Fornasari, A. Mollica, A. Stefanucci and F. Pinnen, 2012. GPE and GPE analogues as promising neuroprotective agents. Mini-Reviews in Med. Chem., 12: 13-23.
    CrossRef  |  Direct Link  |  
  70. Stefanucci, A., F. Pinnen, F. Feliciani, I. Cacciatore, G. Lucente and A. Mollica, 2011. Conformationally constrained histidines in the design of peptidomimetics: Strategies for the χ-space control. Int. J. Mol. Sci., 12: 2853-2890.
    CrossRef  |  Direct Link  |  
  71. Pinnen, F., P. Sozio, I. Cacciatore, C. Cornacchia and A. Mollica, 2011. Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating alzheimer's disease. Archiv Der Pharmazie, 344: 139-148.
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  72. Mollica, A., F. Pinnen, F. Feliciani, A. Stefanucci and G. Lucente, 2011. New potent biphalin analogues containing p-fluoro-L-phenylalanine at the 4,4'positions and non-hydrazine linkers. Amino Acids, 40: 1503-1511.
    Direct Link  |  
  73. Mollica, A., A. Stefanucci, F. Feliciani, G. Lucente and F. Pinnen, 2011. Synthesis of (S)-5,6-dibromo-tryptophan derivatives as building blocks for peptide chemistry. Tetrahedron Letters, 52: 2583-2585.
    CrossRef  |  Direct Link  |  
  74. Torino, D., A. Mollica, F. Pinnen, F. Feliciani and G. Lucente et al., 2010. Synthesis and evaluation of new endomorphin-2 analogues containing (Z)-α,β-didehydrophenylalanine (δZPhe) residues. J. Med. Chem., 53: 4550-4554.
    CrossRef  |  Direct Link  |  
  75. Mollica, A., F. Feliciani, A. Stefanucci, I. Cacciatore, C. Cornacchia, D. Torino and F. Pinnen, 2010. N-(tert)-butyloxycarbonyl-β, β-cyclopentyl-cysteine (acetamidomethyl)-methyl ester for synthesis of novel peptidomimetic derivatives. Protein and Peptide Letters, 17: 925-929.
    PubMed  |  Direct Link  |  
  76. Mollica, A., A. Stefanucci, F. Feliciani, D. Torino, I. Cacciatore, F. Pinnen and G. Lucente, 2010. Facile transformation of glutamic acid into proline residue inside a tripeptide backbone. Tetrahedron Letters, 51: 1333-1335.
    CrossRef  |  Direct Link  |  
  77. Giordano, C., A. Sansone, A. Masi, G. Lucente and P. Punzi, 2010. Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2. Eur. J. Med. Chem., 45: 4594-4600.
    CrossRef  |  Direct Link  |  
  78. Cacciatore, I., C. Cornacchia, F. Pinnen, A. Mollica and A. Di Stefano, 2010. Prodrug approach for increasing cellular glutathione levels. Molecules, 15: 1242-1264.
    CrossRef  |  Direct Link  |  
  79. Torino, D., A. Mollica, F. Pinnen, G. Lucente and F. Feliciani et al., 2009. Synthesis and evaluation of new endomorphin analogues modified at the Pro2 residue. Bioorg. Med. Chem. Letters, 19: 4115-4118.
    CrossRef  |  Direct Link  |  
  80. Torino, D., A. Mollica, F. Pinnen, F. Feliciani, S.Spisani and G. Lucente, 2009. Novel chemotactic For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold: Synthesis and bioactivity. Bioorg. Med. Chem., 17: 251-259.
    CrossRef  |  Direct Link  |  
  81. Mura, P., M. Camalli, G. Campi, G. Lucente and C. Giordano et al., 2009. X-ray crystal structure and conformation of N-(tertbutyloxycarbonyl)-L- methionyl-(1-aminocyclopent-3-ene-1-carbonyl)-L-phenylalanine methyl ester (Boc0-Met1-Cpg2-Phe3-OMe). Z. Kristallogr., 224: 225-228.
    CrossRef  |  Direct Link  |  
  82. Selvatici, R., S. Falzarano, L. Franceschetti, A. Mollica, R. Guerrini, A. Siniscalchi and S. Spisani, 2008. Study of synthetic peptides derived from the PKI55 protein, a protein kinase C modulator, in human neutrophils stimulated by the methyl ester derivative of the hydrophobic N-formyl tripeptide for-Met-Leu-Phe-OH. FEBS J., 275: 449-457.
    CrossRef  |  Direct Link  |  
  83. Mollica, A., G. Guardiani, P. Davis, S.W. Ma and F. Porreca et al., 2007. Synthesis of stable and potent δ/μ opioid peptides: Analogues of H-Tyr-c[D-Cys-Gly-Phe-D-Cys]-OH by ring-closing metathesis. J. Med. Chem., 50: 3138-3142.
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  84. Selvatici, R., S. Falzarano, A. Mollica and S. Spisani, 2006. Signal transduction pathways triggered by selective formylpeptide analogues in human neutrophils. Eur. J. Pharma., 534: 1-11.
    CrossRef  |  PubMed  |  Direct Link  |  
  85. Mollica, A., P. Davis, S.-W. Ma, F. Porreca, J. Lai and V.J. Hruby, 2006. Synthesis and biological activity of the first cyclic biphalin analogues. Bioorg. Med. Chem. Letters, 16: 367-372.
    CrossRef  |  Direct Link  |  
  86. Mollica, A., M.P. Paradisi, K. Varani, S. Spisani and G. Lucente, 2006. Chemotactic peptides: fMLF-OMe analogues incorporating proline-methionine chimeras as N-terminal residue. Bioorg. Med. Chem., 14: 2253-2265.
    CrossRef  |  Direct Link  |  
  87. Mollica, A., M. Paglialunga Paradisi, D. Torino, S. Spisani and G. Lucente, 2006. Hybrid α/β-peptides: For-Met-Leu-Phe-OMe analogues containing geminally disubstituted β2,2- and β3,3-amino acids at the central position. Amino Acids, 30: 453-459.
    CrossRef  |  Direct Link  |  
  88. Aschi, M., A. Mollica, G. Lucente, M.P. Paradisi, F. Mazza, 2006. Conformational properties of β-residue-containing oligopeptides in apolar solvent. J. Mol. Struc., 785: 176-181.
    CrossRef  |  Direct Link  |  
  89. Morera, E., M. Nalli, A. Mollica, M.P. Paradisi and M. Aschi et al., 2005. Peptides containing 4-amino-1,2-dithiolane-4-carboxylic acid (Adt): Conformation of Boc-Adt-Adt-NHMe and NH⋯S interactions. J. Pept. Sci., 11: 104-112.
    CrossRef  |  Direct Link  |  
  90. Mollica, A., P. Davis, S.-W. Ma, J. Lai, F. Porreca and V.J. Hruby, 2005. Synthesis and biological evaluation of new biphalin analogues with non-hydrazine linkers. Bioorg. Med. Chem. Letters, 15: 2471-2475.
    CrossRef  |  Direct Link  |  
  91. Giordano, C., G. Lucente, A. Mollica, M. Nalli and G.P. Zecchini et al., 2004. Hybrid α/β3-petides with proteinogenic side chains. Monosubstituted analogues of the chemotactic tripeptide For-Met-Leu-Phe-OMe. J. Pept. Sci., 10: 510-523.
    CrossRef  |  Direct Link  |  
  92. Paradisi, M.P., A. Mollica, I. Cacciatore, A. Di Stefano and F. Pinnen et al., 2003. Proline-glutamate chimeras in isopeptides. Synthesis and biological evaluation of conformationally restricted glutathione analogues Bioorg. Med. Chem., 11: 1677-1683.
    CrossRef  |  Direct Link  |  
  93. Aschi, M., G. Lucente, F. Mazza, A. Mollica and E. Morera et al., 2003. Peptide backbone folding induced by the Cα-tetrasubstituted cyclic α-amino acids 4-amino-1,2-dithiolane-4-carboxylic acid (Adt) and 1-aminocyclopentane-1-carboxylic acid (Ac5c). A joint computational and experimental study. Org. Biomol. Chem., 1: 1980-1988.
    CrossRef  |  Direct Link  |  
  94. Pagani Zecchini, G., M. Nalli, A. Mollica, G. Lucente, M. Paglialunga Paradisi and S. Spisani, 2002. Isopeptide bonds in chemotactic tripeptides. Synthesis and activity of lysine-containing fMLF analogs. J. Pept. Res., 59: 283-291.
    CrossRef  |  Direct Link  |