Area of Interest:

Biomedical Sciences

100%

Molecualar Biology

62%

Biochemistry

90%

Microbiology

75%

Immunology

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
0

Abstracts
0

Selected Publications

Sydler, T., S. Bragger, M. Handke, S. Hartnack, F.I. Lewis, X. Sidler and E. Brugnera, 2016. Latent porcine circovirus type 2-infected domestic pigs: A potential infection model for the effective development of vaccines against latent or chronic virus induced diseases. Vaccine, 34: 1047-1053.
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Klausmann, S., T. Sydler, A. Summerfield, F.I. Lewis, R. Weilenmann, X. Sidler and E. Brugnera, 2015. T-cell reprogramming through targeted CD4-coreceptor and T-cell receptor expression on maturing thymocytes by latent Circoviridae family member porcine circovirus type 2 cell infections in the thymus. Emerg. Microbes Infect., Vol. 4. 10.1038/emi.2015.15.
CrossRef | Direct Link |
Khaiseb, S., T. Sydler, D. Zimmermann, A. Pospischil, X. Sidler and E. Brugnera, 2011. Coreplication of the major genotype group members of porcine circovirus type 2 as a prerequisite to coevolution may explain the variable disease manifestations. J. Virol., 85: 11111-11120.
CrossRef | Direct Link |
Khaiseb, S., T. Sydler, D. Zimmermann, A. Pospischil, X. Sidler and E. Brugnera, 2011. Porcine circovirus 2 major genotype group members' co-replication as a prerequisite to co-evolution that may explain the variable disease manifestations. J. Virol., Vol. 85. 10.1128/JVI.05156-11.
CrossRef | Direct Link |
Wiederkehr, D.D., T. Sydler, E. Buergi, M. Haessig and D. Zimmermann et al., 2009. A new emerging genotype subgroup within PCV-2b dominates the PMWS epizooty in Switzerland. Vet. Microbiol., 136: 27-35.
CrossRef | Direct Link |
Lu, M., J.M. Kinchen, K.L. Rossman, C. Grimsley and C. de Bakker et al., 2004. Provides biochemical evidence that Dock180, although lacking a DH domain, can have Rho GEF activity. Nat. Struct. Mol. Biol., 11: 756-762.
Brugnera, E., L. Haney, C. Grimsley, M. Lu and S.F. Walk et al., 2002. Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nature Cell Biol., 4: 574-582.
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Gumienny, T.L., E. Brugnera, A.C. Tosello-Trampont, J.M. Kinchen and L.B. Haney et al., 2001. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell, 107: 27-41.
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Brugnera, E., A. Bhandoola, R. Cibotti, Q. Yu and T.I. Guinter et al., 2000. Coreceptor reversal in the thymus: Signaled CD4⁺8⁺ thymocytes initially terminate CD8 transcription even when differentiating into CD8⁺ T cells. Immunity, 13: 59-71.
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