Dr. Ruxandra  Mckinnon
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Dr. Ruxandra Mckinnon

Post-doctoral Fellow
University of Vienna, Austria


Highest Degree
Doctorate in Natural Sciences from University of Vienna, Austria

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Area of Interest:

Biomedical Sciences
100%
Cell Culture
62%
Cell Biology
90%
Molecular Biology
75%
Natural Products
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Unger, C., R. Popescu, B. Giessrigl, D. Laimer and S. Heider et al., 2013. The dichloromethane extract of the ethnomedicinal plant Neurolaena lobata inhibits NPM/ALK expression which is causal for anaplastic large cell lymphomagenesis. Int. J. Oncol., 42: 338-348.
    CrossRef  |  PubMed  |  Direct Link  |  
  2. Popescu, R. and B. Kopp, 2013. The genus Rhododendron: An ethnopharmacological and toxicological review. J. Ethnopharmacol., 147: 42-62.
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Unger, C., R. Popescu, B. Giessrigl, L. Rarova and I. Herbacek et al., 2012. An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis. Int. J. Oncol., 40: 2131-2139.
    CrossRef  |  PubMed  |  Direct Link  |  
  4. Seelinger, M., R. Popescu, P. Seephonkai, J. Singhuber and B. Giessrigl et al., 2012. Fractionation of an extract of Pluchea odorata separates a property indicative for the induction of cell plasticity from one that inhibits a neoplastic phenotype. Evid. Based Complement. Alternat. Med. 10.1155/2012/701927.
    CrossRef  |  PubMed  |  Direct Link  |  
  5. Seelinger, M., R. Popescu, B. Giessrigl, K. Jarukamjorn and C. Unger et al., 2012. Methanol extract of the ethnopharmaceutical remedy Smilax spinosa exhibits anti-neoplastic activity. Int. J. Oncol., 41: 1164-1172.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Rozema, E., R. Popescu, H. Sonderegger, C.W. Huck and J. Winkler et al., 2012. Characterization of glucocerebrosides and the active metabolite 4,8-sphingadienine from Arisaema amurense and Pinellia ternate by NMR and CD spectroscopy and ESI-MS/CID-MS. J. Agric. Food Chem., 60: 7204-7210.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Kizaibek, M., R. Popescu, S. Prinz, H. Upur, J. Singhuber, M. Zehl and B. Kopp, 2012. Towards modernization of the formulation of the traditional uighur medicine herbal preparation Abnormal Savda Munziq. Evid. Based Complement. Alternat. Med 10.1155/2012/863101.
    CrossRef  |  Direct Link  |  
  8. Vlashi, E., C. Lagadec, L. Vergnes, T. Matsutani and K. Masui et al., 2011. Metabolic state of glioma stem cells and nontumorigenic cells. Proc. Nat. Acad. Sci. United States Am., 108: 16062-16067.
    CrossRef  |  Direct Link  |  
  9. Seephonkai, P., R. Popescu, M. Zehl, G. Krupitza, E. Urban and B. Kopp, 2011. Ferruginenes A-C from Rhododendron ferrugineum and their cytotoxic evaluation. J. Nat. Prod., 74: 712-717.
    CrossRef  |  PubMed  |  Direct Link  |  
  10. Popescu, R., E.H. Heiss, F. Ferk, A. Peschel and S. Knasmueller et al., 2011. Ikarugamycin induces DNA damage, intracellular calcium increase, p38 MAP kinase activation and apoptosis in HL-60 human promyelocytic leukemia cells. Mutat. Res./Fundamen. Mol. Mech. Mutagen., 709-710: 60-66.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Gao, H., R. Popescu, B. Kopp and Z. Wang, 2011. Bufadienolides and their antitumor activity. Nat. Prod. Rep., 28: 953-969.
    CrossRef  |  PubMed  |  Direct Link  |  
  12. Bauer, S., J. Singhuber, M. Seelinger, C. Unger and K. Viola et al., 2011. Separation of anti-neoplastic activities by fractionation of a Pluchea odorata extract. Front. Biosci., (Elite Ed.), 3: 1326-1336.
    PubMed  |  Direct Link  |  
  13. Madlener, S., P. Saiko, K. Viola, N. Huttary and N. Stark et al., 2010. Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest and inhibition of lymphendothelial gap formation In Vitro. Br. J. Can., 102: 1361-1370.
    PubMed  |  Direct Link  |  
  14. Gridling, M., R. Popescu, B. Kopp, K.H. Wagner, L. Krenn and G. Krupitza, 2010. Anti-leukaemic effects of two extract types of Lactuca sativa correlate with the activation of Chk2, induction of p21, downregulation of cyclin D1 and acetylation of α-tubulin. Oncol. Rep., 23: 1145-1151.
  15. Stark, N., M. Gridling, S. Madlener, S. Bauer and A. Lackner et al., 2009. A polar extract of the Maya healing plant Anthurium schlechtendalii (Aracea) exhibits strong In vitro anticancer activity. Int. J. Mol. Med., 24: 513-521.
    CrossRef  |  PubMed  |  
  16. Kizaibek, M., B. Kopp, S. Prinz, R. Popescu and H. Upur, 2009. Antiproliferative activity of individual herbs of abnormal savda Munziq on HL-60 cells. Sci. Technol. Rev., 27: 94-98.
    Direct Link  |  
  17. Gridling, M., N. Stark, S. Madlener, A. Lackner and R. Popescu et al., 2009. In vitro anti-cancer activity of two ethno-pharmacological healing plants from Guatemala Pluchea odorata and Phlebodium decumanum. Int. J. Oncol., 34: 1117-1128.
    CrossRef  |  PubMed  |  Direct Link  |  
  18. Bader, Y., S. Madlener, S. Strasser, S. Maier and P. Saiko et al., 2008. Stilbene analogues affect cell cycle progression and apoptosis independently of each other in an MCF-7 array of clones with distinct genetic and chemoresistant backgrounds. Oncol. Rep., 19: 801-810.
    PubMed  |  Direct Link  |  
  19. Popescu, R. and C.E. Gard, 2005. Phytochemical research on Rhododendron kotschyi Simk. (Ericaceae) homeopathic tincture. Timisoara Med. J., 55: 346-347.