Dr. Soriano Ursua Marvin Antonio
My Social Links

Dr. Soriano Ursua Marvin Antonio

Professor
Instituto Politecnico Nacional, Mexico


Highest Degree
Ph.D. in Medicine from Instituto Politecnico Nacional, Mexico

Share this Profile

Area of Interest:

Medicine
100%
Medicinal Chemistry
62%
Molecular Modelling
90%
Neurology
75%
Drug Targets
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Soriano-Ursua, M.A., M. Bello, C.F. Hernandez-Martinez, I. Santillan-Torres and R. Guerrero-Ramirez et al., 2019. Cell-based assays and molecular dynamics analysis of a boron-containing agonist with different profiles of binding to human and guinea pig beta2 adrenoceptors. Eur. Biophys. J., 48: 83-97.
    CrossRef  |  Direct Link  |  
  2. Demianenko, E., A. Rayevsky, M.A. Soriano-Ursua and J.G. Trujillo-Ferrara, 2019. Theoretical coupling and stability of boronic acid adducts with catecholamines. Lett. Drug Des. Discov., 16: 467-475.
    CrossRef  |  Direct Link  |  
  3. Correa-Basurto, A.M., A. Romero-Castro, J. Correa-Basurto, M. Hernandez-Rodriguez and M.A. Soriano-Ursua et al., 2019. Pharmacokinetics and tissue distribution of N-(2-hydroxyphenyl)-2-propylpentanamide in Wistar rats and its binding properties to human serum albumin. J. Pharmaceut. Biomed. Anal., 162: 130-139.
    CrossRef  |  Direct Link  |  
  4. Coaviche-Yoval, A., H. Luna, R. Tovar-Miranda, M.A. Soriano-Ursua and J.G. Trujillo-Ferrara, 2019. Synthesis and biological evaluation of novel 2,3-disubstituted benzofuran analogues of GABA as neurotropic agents. Med. Chem., 15: 77-86.
    CrossRef  |  Direct Link  |  
  5. Segura-Uribe, J.J., E.D. Farfan-Garcia, C. Guerra-Araiza, F.J. Cipres-Flores, P. Garcia-dela Torre and M.A. Soriano-Ursua, 2018. Differences in brain regions of three mice strains identified by label-free micro-Raman. Spectrosc. Lett., 51: 356-366.
    CrossRef  |  Direct Link  |  
  6. Pinto-Almazan, R., J.J. Segura-Uribe, M.A. Soriano-Ursua, E.D. Farfan-Garcia, J.M. Gallardo and C. Guerra-Araiza, 2018. Effect of tibolone pretreatment on kinases and phosphatases that regulate the expression and phosphorylation of Tau in the hippocampus of rats exposed to ozone. Neural Regener. Res., 13: 440-448.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Ocampo-Nestor, A.L., R.M. Lopez-Mayorga, E.F. Castillo-Henkel, I.I. Padilla-Martinez, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2018. Design, synthesis and in vitro evaluation of a Dopa-organoboron compound that acts as a bladder relaxant through non-catecholamine receptors. Mol. Diversity, (In Press). 10.1007/s11030-018-9883-7.
    CrossRef  |  Direct Link  |  
  8. Lopez-Cabrera, Y., E.L. Castillo-Garcia, J.A. Altamirano-Espino, T. Perez-Capistran, E.D. Farfan-Garcia, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2018. Profile of three boron-containing compounds on the body weight, metabolism and inflammatory markers of diabetic rats. J. Trace Elem. Med. Biol., 50: 424-429.
    CrossRef  |  Direct Link  |  
  9. Farfan-Garcia, E.D., E.L. Castillo-Garcia and M.A. Soriano-Ursua, 2018. More than boric acid: Increasing relevance of boron in medicine. World J. Transl. Med., 7: 1-4.
    CrossRef  |  Direct Link  |  
  10. Bello, M., C. Guadarrama-Garcia, L.M. Velasco-Silveyra, E.D. Farfan-Garcia and M.A. Soriano-Ursua, 2018. Several effects of boron are induced by uncoupling steroid hormones from their transporters in blood. Med. Hypotheses, 118: 78-83.
    CrossRef  |  Direct Link  |  
  11. Andrade-Jorge, E., L.A. Sanchez-Labastida, M.A. Soriano-Ursua, J.A. Guevara-Salazar and J.G. Trujillo-Ferrara, 2018. Isoindolines/isoindoline-1,3-diones as AChE inhibitors against Alzheimer's disease, evaluated by an improved ultra-micro assay. Med. Chem. Res., 27: 2187-2198.
    CrossRef  |  Direct Link  |  
  12. Andrade-Jorge, E., J. Bribiesca-Carlos, F.J. Martinez-Martinez, M.A. Soriano-Ursua, I.I. Padilla-Martinez and J.G. Trujillo-Ferrara, 2018. Crystal structure, DFT calculations and evaluation of 2-(2-(3,4-dimethoxyphenyl)ethyl)isoindoline-1,3-dione as AChE inhibitor. Chem. Cent. J., Vol. 12. 10.1186/s13065-018-0442-1.
    CrossRef  |  Direct Link  |  
  13. Andrade-Jorge, E., A.K. Garcia-Avila, A.L. Ocampo-Nestor, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2018. Advances of bioinformatics applied to development and evaluation of boron-containing compounds. Curr. Org. Chem., 22: 298-306.
    CrossRef  |  Direct Link  |  
  14. Perez-Rodriguez, M., E. Garcia-Mendoza, E.D. Farfan-Garcia, B.C. Das and F.J. Cipres-Flores et al., 2017. Not all boronic acids with a five-membered cycle induce tremor, neuronal damage and decreased dopamine. NeuroToxicology, 62: 92-99.
    CrossRef  |  Direct Link  |  
  15. Perez, T., E.D. Farfan-Garcia, M.A. Soriano-Ursua, L. Manuel-Apolinar and M.C. Castillo et al., 2017. Effects of hydrogen peroxide on phenylephrine-induced contraction of abdominal or thoracic aorta from adult rats. Int. J. Clin. Exp. Pathol., 10: 5105-5116.
    Direct Link  |  
  16. Ocampo-Nestor, A.L., J.G. Trujillo-Ferrara, A. Abad-Garcia, C. Reyes-Lopez, S. Geninatti-Crich and M.A. Soriano-Ursua, 2017. Boron's journey: Advances in the study and application of pharmacokinetics. Expert Opin. Therapeut. Patents, 27: 203-215.
    CrossRef  |  Direct Link  |  
  17. Neri-Bazan, R.M., J. Garcia-Machorro, D. Mendez-Luna, L.E. Tolentino-Lopez and F. Martinez-Ramos et al., 2017. Design, in silico studies, synthesis and in vitro evaluation of oseltamivir derivatives as inhibitors of neuraminidase from influenza A virus H1N1. Eur. J. Med. Chem., 128: 154-167.
    CrossRef  |  Direct Link  |  
  18. Julia, J., C.F.F. Jimena, F.G.E. Dalet, T.F.J. Guadalupe and S.U.M. Antonio, 2017. Scope of lipid nanoparticles in neuroscience: Impact on the treatment of neurodegenerative diseases. Curr. Pharmaceut. Des., 23: 3120-3133.
    CrossRef  |  Direct Link  |  
  19. Garcia-Avila, A.K., E.D. Farfan-Garcia, J.A. Guevara-Salazar, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2017. Scope of translational medicine in developing boron-containing compounds for therapeutics. World J. Transl. Med., 6: 1-9.
    CrossRef  |  Direct Link  |  
  20. Garrido-Acosta, O., S.E. Meza-Toledo, L. Anguiano-Robledo, M.A. Soriano-Ursua, J. Correa-Basurto, A. Davood and G. Chamorro-Cevallos, 2016. Anticonvulsant and toxicological evaluation of parafluorinated/chlorinated derivatives of 3-hydroxy-3-ethyl-3-phenylpropionamide. BioMed Res. Int., Vol. 2016. 10.1155/2016/3978010.
    CrossRef  |  Direct Link  |  
  21. Farfan-Garcia, E.D., N.T. Castillo-Mendieta, F.J. Cipres-Flores, I.I. Padilla-Martinez, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2016. Current data regarding the structure-toxicity relationship of boron-containing compounds. Toxicol. Lett., 258: 115-125.
    CrossRef  |  Direct Link  |  
  22. Farfan-Garcia, E.D., M. Perez-Rodriguez, C. Espinosa-Garcia, N.T. Castillo-Mendieta and M. Maldonado-Castro et al., 2016. Disruption of motor behavior and injury to the CNS induced by 3-thienylboronic acid in mice. Toxicol. Applied Pharmacol., 307: 130-137.
    CrossRef  |  Direct Link  |  
  23. Soriano-Ursua, M.A., J.G. Trujillo-Ferrara, J.A. Arias-Montano and R. Villalobos-Molina, 2015. Insights into a defined secondary binding region on β-adrenoceptors and putative roles in ligand binding and drug design. MedChemComm, 6: 991-1002.
    CrossRef  |  Direct Link  |  
  24. Soriano-Ursua, M.A., J.A. Arias-Montano, J. Correa-Basurto, C.F. Hernandez-Martinez and Y. Lopez-Cabrera et al., 2015. Insights on the role of boron containing moieties in the design of new potent and efficient agonists targeting the β2 adrenoceptor. Bioorg. Med. Chem. Lett., 25: 820-825.
    CrossRef  |  Direct Link  |  
  25. Mendez, J.P., J.C. Zenteno, A. Coronel, M.A. Soriano-Ursua and E.Y. Valencia-Villalvazo et al., 2015. Triallelic digenic mutation in the prokineticin 2 and GNRH receptor genes in two brothers with normosmic congenital hypogonadotropic hypogonadism. Endocr. Res., 40: 166-171.
    CrossRef  |  Direct Link  |  
  26. Madrigal-Santillan, E., M. Bautista, J.A. Gayosso-De-Lucio, Y. Reyes-Rosales and A. Posadas-Mondragon et al., 2015. Hepatoprotective effect of Geranium schiedeanum against ethanol toxicity during liver regeneration. World J. Gastroenterol., 21: 7718-7729.
    CrossRef  |  PubMed  |  Direct Link  |  
  27. Soriano-Ursua, M.A., E.D. Farfan-Garcia, Y. Lopez-Cabrera, E. Querejeta and J.G. Trujillo-Ferrara, 2014. Boron-containing acids: Preliminary evaluation of acute toxicity and access to the brain determined by Raman scattering spectroscopy. Neurotoxicology, 40: 8-15.
    CrossRef  |  
  28. Soriano-Ursua, M.A., B.C. Das and J.G. Trujillo-Ferrara, 2014. Boron-containing compounds: Chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy. Expert Opin. Therapeut. Patents, 24: 485-500.
    CrossRef  |  Direct Link  |  
  29. Segura-Cabrera, A., C.A. Garcia-Perez, F.J. Cipres-Flores, R.I. Cuevas-Hernandez, J.G. Trujillo-Ferrara, J. Correa-Basurto and M.A. Soriano-Ursua, 2014. Molecular dynamics simulations to explore the active/inactive conformers of guinea pig β2 adrenoceptor for the selective design of agonists or antagonists. Mol. Simul., 40: 1244-1254.
    CrossRef  |  Direct Link  |  
  30. Ramirez-San Juan, E., M.A. Soriano-Ursua, J. Espinosa-Raya, J. Correa-Basurto and J.G. Trujillo-Ferrara et al., 2014. Anticonvulsant effects of bis-1, 4-dihydropyridines and the probable role of L-type calcium channels suggested by docking simulations. Med. Chem. Res., 23: 5149-5159.
    CrossRef  |  Direct Link  |  
  31. Soriano-Ursua, M.A., J.G. Trujillo-Ferrara, J. Correa-Basurto and S. Vilar, 2013. Recent structural advances of β1 and β2 adrenoceptors yield keys for ligand recognition and drug design. J. Med. Chem., 56: 8207-8223.
    CrossRef  |  
  32. Soriano-Ursua, M.A., E.D. Farfan-Garcia and J.G. Trujillo-Ferrara, 2013. Notable advances in medicine from the structural biology of catecholamine-receptors. Acta Med. Politecnica, 1: 17-22.
  33. Soriano-Ursua, M.A., D. McNaught-Flores, J. Correa-Basurto, J.A. Arias-Montano, J.G. Trujillo-Ferrara, 2013. Histamine modulates isoproterenol efficacy at the β2 adrenoceptor: Inferences regarding allosteric modulation by imidazole-containing compounds. Biochem. Physiol., Vol. 2. 10.4172/2168-9652.1000114.
    CrossRef  |  
  34. Martinez-Ramos, F., Y. Fonseca-Sabater, M.A. Soriano-Ursua, E. Torres and M.C. Rosales-Hernandez et al., 2013. O-Alkylselenenylated benzoic acid accesses several sites in serum albumin according to fluorescence studies, Raman spectroscopy and theoretical simulations. Protein Pept. Lett., 20: 705-714.
    Direct Link  |  
  35. Farfan-Garcia, E.D., J.G. Trujillo-Ferrara, M.C. Castillo-Hernandez, C.H. Guerra-Araiza and M.A. Soriano-Ursua, 2013. Insights into the structural biology of GPCRs impacts drug design for CNS neurodegenerative processes. Neural. Regene. Res., 8: 2290-2302.
  36. Castro, J.J., J.P. Mendez, R.M. Coral-Vazquez, M.A. Soriano-Ursua and P. Damian-Matsumura et al., 2013. In vitro and molecular modeling analysis of two mutant desert hedgehog proteins associated with 46,XY gonadal dysgenesis. DNA Cell Biol., 32: 524-530.
    CrossRef  |  Direct Link  |  
  37. Soriano-Ursua, M.A., D.A. McNaught-Flores, G. Nieto-Alamilla, A. Segura-Cabrera, J. Correa-Basurto, J.A. Arias-Montano and J.G. Trujillo-Ferrara, 2012. Cell-based and in-silico studies on the high intrinsic activity of two boron-containing salbutamol derivatives at the human β-adrenoceptor. Bioorg. Med. Chem., 20: 933-941.
    CrossRef  |  
  38. Amezcua-Gutierrez, M.A., F.J. Cipres-Flores, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2012. Clinical implications of recent insights into the structural biology of β adrenoceptor. Curr. Drug Targets, 13: 1336-1346.
    CrossRef  |  
  39. Soriano-Ursua, M.A., T. Mancilla-Percino, J. Correa-Basurto, E. Querejeta and J.G. Trujillo-Ferrara, 2011. Give boron a chance: Boron containing compounds reach ionotropic and metabotropic transmembrane receptors. Mini Rev. Med. Chem., 11: 1031-1038.
    Direct Link  |  
  40. Soriano-Ursua, M.A., J.O. Ocampo-Lopez, K. Ocampo-Mendoza, J.G. Trujillo-Ferrara and J. Correa-Basurto, 2011. Theoretical study of 3-D molecular similarity and ligand binding modes of orthologous human and rat D2 dopamine receptors. Comput. Biol. Med., 41: 537-545.
    CrossRef  |  
  41. Soriano-Ursua, M.A., J. Correa-Basurto, J.G. Trujillo-Ferrara and A.J. Kaumann, 2011. Homology model and docking studies on porcine β2 adrenoceptor: Description of two binding sites. J. Mol. Model., 17: 2525-2538.
    CrossRef  |  
  42. Lopez-Hernandez, L.B., D. van Heusden, M.A. Soriano-Ursua, L. Figuera-Villanueva and N.A. Vazquez-Cardenas et al., 2011. Genotype-phenotype discordance in a Duchenne muscular dystrophy patient due to a novel mutation: Insights into the shock absorber function of dystrophin. Rev. Neurol., 52: 720-724.
    Direct Link  |  
  43. Soriano-Ursua, M.A., J.G. Trujillo-Ferrara, J. Alvarez-Cedillo and J. Correa-Basurto, 2010. Docking studies on a refined human β2 adrenoceptor model yield theoretical affinity values in function with experimental values for R-ligands but not for S-antagonists. J. Mol. Model., 16: 401-409.
    CrossRef  |  
  44. Soriano-Ursua, M.A., J.G. Trujillo-Ferrara and J. Correa-Basurto, 2010. Scope and difficulty in generating theoretical insights regarding ligand recognition and activation of the β2 adrenergic receptor. J. Med. Chem., 53: 923-932.
    CrossRef  |  
  45. Soriano-Ursua, M.A., J. Correa-Basurtoa, I. Valencia-Hernandez, M.A. Amezcua-Gutierrez, I.I. Padilla-Martinez, J.G. Trujillo-Ferrara, 2010. Design, synthesis and in vitro evaluation of (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenyl hydrogen phenylboronate: A novel salbutamol derivative with high intrinsic efficacy on the β2 adrenoceptor. Bioorg. Med. Chem. Lett., 20: 5623-5629.
    CrossRef  |  
  46. Soriano-Ursua, M.A., J. Correa-Basurto, J. Romero-Huerta, O. Elizalde-Solis, L.A. Galicia-Luna and J.G. Trujillo-Ferrara, 2010. Pharmacokinetic parameters and a theoretical study about metabolism of BR-AEA (a salbutamol derivative) in rabbit. J. Enzyme Inhibition Med. Chem., 25: 340-346.
    CrossRef  |  Direct Link  |  
  47. Soriano-Ursua, M.A., J.G. Trujillo-Ferrara and J. Correa-Basurto, 2009. Homology modeling and Flex-ligand docking studies on the guinea pig β2 adrenoceptor: Structural and experimental similarities/differences with the human β2. J. Mol. Model., 15: 1203-1211.
    CrossRef  |  
  48. Soriano-Ursua, M.A., I. Valencia-Hernandez, M.G. Arellano-Mendoza, J. Correa-Basurto and J.G. Trujillo-Ferrara, 2009. Synthesis, pharmacological and in silico evaluation of 1-(4-di-hydroxy-3, 5-dioxa-4-borabicyclo [4.4. 0] deca-7, 9, 11-trien-9-yl)-2-(tert-butylamino) etanol, a compound designed to act as a β2 adrenoceptor agonist. Eur. J. Med. Chem., 44: 2840-2846.
    CrossRef  |  Direct Link  |