Dr. Luciana Scotti
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Dr. Luciana Scotti

Senior Scientist
Federal University of Paraiba, Brazil

Highest Degree
Ph.D. in Pharmacy from Federal University of Paraiba, Brazil

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Biography

Dr. Luciana Scotti is currently working as Senior Researcher. She has completed her Ph.D. in Pharmacy from Federal University of Paraiba, Brazil. Her main area of interest focuses on Molecular Sciences and Computer Sciences. Her area of expertise includes Bioinformatics, Neglected Disease, Molecular Modeling, QSAR, and Natural Products. She has published 35 research articles in journals as well as 1 book and 2 chapters in book contributed as author/co-author.

Area of Interest:

Molecular Sciences
100%
Bioinformatics
62%
Molecular Modeling
90%
Natural Products
75%
Neglected Disease
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Scotti, L., H. Ishiki, F.J.B. Mendonca, M.S. Da Silva and M.T. Scotti, 2015. In-silico analyses of natural products on Leishmania enzyme targets. Mini Rev. Med. Chem., 15: 253-269.
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  2. Mendonca, J., F.J.B., L. Scotti, H. Ishiki, S.P.S. Botelho, M.S. Da Silva and M.T. Scotti, 2015. Benzo-and Thienobenzo-Diazepines: Multi-target drugs for CNS disorders. Mini Rev. Med. Chem., 15: 630-647.
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  3. Soares, G.C.D.S., L.D.M. De Silva, H.D.A. Carlos, L. Scotti and M.T. Scotti, 2014. Quantitative structure-sorption relationships of pesticides used in the sugarcane industry in the Northern coastal area of Paraiba State, Brazil. Atla-Alternat. Lab. Anim., 42: 81-90.
  4. Scotti, L., M.T. Scotti, V.B. Silva, S.R.L. Santos, S.C.H. Cavalcanti and F.J.B. Mendonca, Jr., 2014. Chemometric studies on potential larvicidal compounds against Aedes aegypti. Med. Chem., 10: 201-210.
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  5. Scotti, L., M.T. Scotti, H. Ishiki, , F.J.B. Mendonca, Jr., J.F. Tavares and M.S. da Silva, 2014. Prediction of anticancer activity of diterpenes isolated from the paraiban flora through a PLS model and molecular surfaces. Natural Product Commun., 9: 609-612.
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  6. Scotti, L., F.J.B. Mendonca, Jr., M.S. da Silva, I.R. Pitta and M.T. Scotti, 2014. Biochemical changes evidenced in Alzheimer's disease: A mini-review. Lett. Drug Design Discovery, 11: 240-248.
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  7. Scotti, L., E. de Oliveira Lima, M.S. da Silva, H. Ishiki and I. de Oliveira Lima et al., 2014. Docking and PLS studies on a set of Thiophenes RNA polymerase inhibitors against Staphylococcus aureus. Curr. Topics Med. Chem., 14: 64-80.
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  8. Luis, J.A., T.M. De Aquino, B.F. Lira, F.A. Petronio Filho, M.T. Scotti, L. Scotti and F.J. Mendonca, Jr., 2014. Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1, 3-thiazolium-and 1, 3, 4-thiadiazolium-5-methylthio-and 5-tioacetate derivatives. Acta Pharmaceut., 64: 233-245.
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  9. Ishiki, H., F.J.B. Mendonca, Jr., P.F. Santos, J.F. Tavares, M.S. Silva and M.T. Scotti, 2014. Theoretical research into anticancer activity of diterpenes isolated from the paraiban flora. Natural Prod. Commun., 9: 911-914.
  10. Guimaraes, A.G., L. Scotti, M.T. Scotti, F.J.B. Mendonca, Jr. and N.S.R. Melo et al., 2014. Evidence for the involvement of descending pain-inhibitory mechanisms in the attenuation of cancer pain by carvacrol aided through a docking study. Life Sci., 116: 8-15.
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  11. De Araujo, R.S.A., F.Q.S. Guerra, E. de O. Lima, C.A. de Simone and J.F. Tavares et al., 2013. Synthesis, Structure-Activity Relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity. Int. J. Mol. Sci., 14: 1293-1309.
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  12. Souza, B., T. De Oliveira, T. Aquino, M. de Lima and I. Pitta et al., 2012. Preliminary antifungal and cytotoxic evaluation of synthetic cycloalkyl [b] thiophene derivatives with PLS-DA analysis. Acta Pharmaceut., 62: 221-236.
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  13. Scotti, M.T., V. Emerenciano, M.J. Ferreira, L. Scotti, R. Stefani, M.S. da Silva and F.J.B. Mendonca, Jr., 2012. Self-organizing maps of molecular descriptors for sesquiterpene lactones and their application to the chemotaxonomy of the asteraceae family. Molecules, 17: 4684-4702.
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  14. Scotti, L., M.T. Scotti, E. de Oliveira Lima, M.S. da Silva and M. do Carmo Alves de Lima et al., 2012. Experimental methodologies and evaluations of computer-aided drug design methodologies applied to a series of 2-aminothiophene derivatives with antifungal activities. Molecules, 17: 2298-2315.
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  15. Scotti, L., J.F. Tavares, M.S.D. Silva, E.V. Falcao, G.C.D.S. Soares and M.T. Scotti, 2012. Chemotaxonomy of three genera of the annonaceae family using self-organizing maps and 13C NMR data of diterpenes. Quimica Nova, 35: 2146-2152.
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  16. Scotti, L., H. Ishiki, M.J.P. Ferreira, F.J.B. Mendonca, Jr., V. de P Emerenciano, M.S Silva and M.T. Scotti, 2012. In silico methods applied in food chemistry: A short review with bitter and mutagenic compounds. Lett. Drug Design Discovery, 9: 527-534.
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  17. Rossini, M., M.T. Scotti, M.V. Correia, H.H. Fokoue and L. Scotti et al., 2012. Sesquiterpene lactones with anti-hepatitis C virus activity using molecular descriptors. Lett. Drug Design Discovery, 9: 881-890.
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  18. Dos Anjos, J.V.D., R.M. Srivastava, J.H. Costa-Silva, L. Scotti and M.T. Scotti et al., 2012. Comparative computational studies of 3, 4-Dihydro-2, 6-diaryl-4-oxo-pyrimidine-5-carbonitrile derivatives as potential antinociceptive agents. Molecules, 17: 809-819.
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  19. Correia, M.V., H.H. Fokoue, M.J.P. Ferreira, L. Scotti and M.T. Scotti et al., 2012. Self-organizing maps as a good tool for classification of subfamily Astereoideae. J. Med. Plants Res., 6: 1207-1218.
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  20. Scotti, L., M.B. Fernandes, E. Muramatsu, V.D.P. Emereciano, J.F. Tavares, M.S.D. Silva and M.T. Scotti, 2011. 13C NMR spectral data and molecular descriptors to predict the antioxidant activity of flavonoids. Braz. J. Pharm. Sci., 47: 241-249.
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  21. Scotti, L., M.B. Fernandes, E. Muramatsu, K.F. Pasqualoto and V.D.P. Emereciano et al., 2011. Self-organizing maps and VolSurf approach to predict aldose reductase inhibition by flavonoid compounds. Braz. J. Pharmacogn., 21: 170-180.
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  22. Fernandes, M.B., M. Rossini, R. Stefani, L. Tavares and V. de Paulo Emerenciano et al., 2011. Volsurf descriptors to analyse anti-HCV and cytotoxic activities of sesquiterpene lactones from asteraceae family. Lett. Drug Design Discovery, 8: 44-58.
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  23. Scotti, L., E.I. Ferreira, M.S.D. Silva and M.T. Scotti, 2010. Chemometric studies on natural products as potential inhibitors of the NADH oxidase from Trypanosoma cruzi using the VolSurf approach. Molecules, 15: 7363-7377.
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  24. Scotti, L., M.T. Scotti, K.F.M. Pasqualoto, V.D.S. Bolzani and E.I. Ferreira, 2009. Molecular physicochemical parameters predicting antioxidant activity of Brazilian natural products. Rev. Brasil. Farmacognosia, 19: 908-913.
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  25. Scotti, L., M.T. Scotti, H.M. Ishiki, M.J.P. Ferreira, V.P. Emerenciano and E.I. Ferreira, 2008. QSAR Analisys: A New Method IN Food Research. In: Progress in Food Chemistry, Koeffer, E.N. (Ed.). Nova Science Publishers, Inc, USA., pp: 201-215.
  26. Scotti, L., M.T. Scotti, H.M. Ishiki, M.J. Ferreira and V.P. Emerenciano et al., 2007. Quantitative elucidation of the structure-bitterness relationship of cynaropicrin and grosheimin derivatives. Food Chem., 105: 77-83.
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  27. Scotti, L., F.J.B. Mendonca Junior, D.R.M. Moreira, M.S. da Silva, I.R. Pitta and M.T. Scotti, 2002. SAR, QSAR and docking of anticancer flavonoids and variants: A review. Curr. Top. Med. Chem., 12: 2785-2809.
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