Dr. Maria Helena Andrade Santana
Research ScientistUniversidade Estadual de Campinas, Brazil
Highest Degree
Ph.D. in Mechanical Engineering from Universidade Estadual de Campinas, Brazil
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Universidade Estadual de Campinas, Brazil
Biography
Dr. Maria Helena obtained her Masters degree in Science and Technology of Food from University of Campinas (1980) and DSc at Mechanical Engineering from University of Campinas, Brazil, and Post-doctoral studies at Chemical Engineering from North Carolina State University (USA) (1993). Then she started as Assistant Professor at the School of Chemical Engineering of the University of Campinas (1972). Presently is full Professor at the School of Chemical Engineering from the University of Campinas., teaches in undergraduate and graduate levels. She also coordinates the Laboratory for Development of Biotechnological Processes, where develops researches in three main areas: 1. Encapsulation and controlled release of drugs and cosmetics using nanop or micro particles and/or fibers. 2. Submerged fermentation and solid fermentation for production of hyaluronic acidc and humic acids. 3. Preparation and characterization of platelet-rich plasma for applications in regenerative therapies. She was elected member of the National Academy of Engineering (2014). She has 100 publication in scientific journals as well as 73 proceeding as author/co-author. She is also supervising several PhD and Masters Students.
Area of Interest:
Pharmacology and Toxicology
100%
Fermentation
62%
Micro-structured Biomaterials
90%
Platelet Rich Plasma
75%
Pharmaceutical Applications
55%
Research Publications in Numbers
Books
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Chapters
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Articles
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Selected Publications
- Severino, P., M. Szymanski, M. Favaro, A.R. Azzoni and M.V. Chaud et al., 2015. Development and characterization of a cationic lipid nanocarrier as non-viral vector for gene therapy. Eur. J. Pharmaceut. Sci., 66: 78-82.
CrossRef | Direct Link | - Severino, P., T. Andreani, A. Jager, M.V. Chaud, M.H.A. Santana, A.M. Silva and E.B. Souto, 2014. Solid lipid nanoparticles for hydrophilic biotech drugs: Optimization and cell viability studies (Caco-2 & HEPG-2 cell lines). Eur. J. Med. Chem., 81: 28-34.
CrossRef | Direct Link | - Severino, P., C.F. Da Silva, T.C.T. Dalla Costa, H. Silva, M.V. Chaud, M.H.A. Santana and E.B. Souto, 2014. In vivo absorption of didanosine formulated in pellets composed of chitosan microspheres. In vivo, 28: 1045-1050.
Direct Link | - Rodrigues, A.A., J.F. Lana, A.C. Luzo, M.H. Santana, A.G. Perez, D.B. Lima-Silva and W.D. Belangero, 2014. Platelet-Rich Plasma and Tissue Engineering. In: Platelet-Rich Plasma: Regenerative Medicine: Sports Medicine, Orthopedic and Recovery of Musculoskeletal Injuries, Lana, J.F.S.D., M.H.A. Santana, W.D. Belangero and A.C.M. Luzo (Eds.). Springer, Berlin, Germany, ISBN: 978-3-642-40116-9, pp: 139-151.
Direct Link | - Quinalia, M.B. and M.H.A. Santana, 2014. Elasticity of liposomes sized by shearing and incorporation of CH8 nitrochalcone. Adv. Sci. Eng. Med., 6: 618-624.
CrossRef | Direct Link | - Perez, A.G.M., J.F.S. Lana, A.A. Rodrigues, A.C.M. Luzo, W.D. Belangero and M.H.A. Santana, 2014. Relevant aspects of centrifugation step in the preparation of platelet-rich plasma. ISRN Hematol. 10.1155/2014/176060.
CrossRef | Direct Link | - Perez, A.G., J.F. Lana, A.A. Rodrigues, A.C. Luzo, W.D. Belangero and M.H. Santana, 2014. Challenges and a Feasible Strategy for Studies and Standardization of Platelet-Rich Plasma. In: Platelet-Rich Plasma: Regenerative Medicine: Sports Medicine, Orthopedic and Recovery of Musculoskeletal Injuries, Lana, J.F.S.D., M.H.A. Santana, W.D. Belangero and A.C.M. Luzo (Eds.). Springer, Berlin, Germany, ISBN: 978-3-642-40116-9, pp: 119-138.
Direct Link | - Perez, A.G., A.A. Rodrigues, A.C. Luzo, J.F. Lana, W.D. Belangero and M.H. Santana, 2014. Fibrin network architectures in pure platelet-rich plasma as characterized by fiber radius and correlated with clotting time. J. Mater. Sci.: Mater. Med., 25: 1967-1977.
CrossRef | Direct Link | - Motta, F.L. and M.H.A. Santana, 2014. Solid-state fermentation for humic acids production by a Trichoderma reesei strain using an oil palm empty fruit bunch as the substrate. Applied Biochem. Biotechnol., 172: 2205-2217.
CrossRef | Direct Link | - Motta, F.L. and M.H.A. Santana, 2014. Comparison of humic acids production by Trichoderma viride and Trichoderma reesei using the submerged fermentation of oil palm empty fruit bunch. Afr. J. Biotechnol., 13: 1067-1074.
Direct Link | - Martinez, R.M., A.A.M. Shimojo and M.H.A. Santana, 2014. Rheological properties of citrus pectin dispersions and its blends with polyquaternium-7 and colloidal particles. J. Applied Polym. Sci., Vol. 131, No. 15. 10.1002/app.40583.
CrossRef | Direct Link | - Lana, J.F., A. Weglein, E. Vicente, A.G. Perez and A.A. Rodrigues et al., 2014. Platelet Rich Plasma and Its Growth Factors: The State of the Art. In: Platelet-Rich Plasma: Regenerative Medicine: Sports Medicine, Orthopedic and Recovery of Musculoskeletal Injuries, Lana, J.F.S.D., M.H.A. Santana, W.D. Belangero and A.C.M. Luzo (Eds.). Springer, Berlin, Germany, ISBN: 978-3-642-40116-9, pp: 1-59.
Direct Link | - De Melo Barbosa, R., C.L.L. Finkler, P. Severino and M.H.A. Santana, 2014. Influence of polyethylene glycol-8-lauryl ester in the structural lipid of the elastic liposomes. Afr. J. Pharm. Pharmacol., 8: 969-977.
Direct Link | - Bastos, R.G., F.L. Motta and M.H.A. Santana, 2014. Oxygen transfer in solid-state cultivation under controlled moisture conditions. Applied Biochem. Biotechnol., 174: 708-718.
CrossRef | Direct Link | - Souto, E.B., P. Severino, R. Basso and M.H.A. Santana, 2013. Encapsulation of Antioxidants in Gastrointestinal-Resistant Nanoparticulate Carriers. In: Oxidative Stress and Nanotechnology: Methods and Protocols, Armstrong, D. and D.J. Bharali (Eds.). Chapter 3, Humana Press, New York, USA., ISBN: 978-1-62703-474-6, pp: 37-46.
Direct Link | - Shimojo, A.A.M., A.M.B. Pires, L.G. de la Torre and M.H.A. Santana, 2013. Influence of particle size and fluid fraction on rheological and extrusion properties of crosslinked hyaluronic acid hydrogel dispersions. J. Applied Polym. Sci., 128: 2180-2185.
CrossRef | Direct Link | - Severino, P., J.F. Fangueiro, S.V. Ferreira, R. Basso and M.V. Chaud et al., 2013. Nanoemulsions and nanoparticles for non-melanoma skin cancer: Effects of lipid materials. Clin. Translational Oncol., 15: 417-424.
CrossRef | Direct Link | - Severino, P., E.B. Souto, S.C. Pinho and M.H.A. Santana, 2013. Hydrophilic coating of mitotane-loaded lipid nanoparticles: Preliminary studies for mucosal adhesion. Pharmaceut. Dev. Technol., 18: 577-581.
CrossRef | Direct Link | - Perez, A.G., R. Lichy, J.F.S. Lana, A.A. Rodrigues, A.C.M. Luzo, W.D. Belangero and M.H.A. Santana, 2013. Prediction and modulation of platelet recovery by discontinuous centrifugation of whole blood for the preparation of pure platelet-rich plasma. BioRes. Open Access, 2: 307-314.
CrossRef | Direct Link | - Oliveira, A.H., C.C. Ogrodowski, A.C.D. Macedo, M.H.A. Santana and L.R. Goncalves, 2013. Cashew apple juice as microbial cultivation medium for non-immunogenic hyaluronic acid production. Braz. J. Microbiol., 44: 1097-1104.
CrossRef | Direct Link | - Lana, J.F.S.D., M.H.A. Santana, W.D. Belangero and A.C.M. Luzo, 2013. Platelet-Rich Plasma: Regenerative Medicine: Sports Medicine, Orthopedic and Recovery of Musculoskeletal Injuries. Springer, New York, USA., ISBN-13: 9783642401176, Pages: 377.
- Kido, H.W., P. Oliveira, N.A. Parizotto, M.C. Crovace and E.D. Zanotto et al., 2013. Histopathological, cytotoxicity and genotoxicity evaluation of Biosilicate® glass-ceramic scaffolds. J. Biomed. Mater. Res. Part A, 101: 667-673.
CrossRef | Direct Link | - Grando, C.R.C., C.A. Guimaraes, L.P. Mercuri, J.D.R. Matos and M.H.A. Santana, 2013. Preparation and characterization of solid lipid nanoparticles loaded with racemic mitotane. J. Colloid Sci. Biotechnol., 2: 140-145.
CrossRef | Direct Link | - Ferrari, F.A., F.L. Motta, R.G. Bastos and M.H.A. Santana, 2013. The solid-state cultivation of Streptococcus zooepidemicus in polyurethane foam as a strategy for the production of hyaluronic acid. Applied Biochem. Biotechnol., 170: 1491-1502.
CrossRef | Direct Link | - De Melo Barbosa, R., C.L. Luna Finkler, M.V.L. Bentley and M.H.A. Santana, 2013. Physicochemical characterization of surfactant incorporating vesicles that incorporate colloidal magnetite. J. Liposome Res., 23: 47-53.
CrossRef | Direct Link | - Benedini, L.J. and M.H.A. Santana, 2013. Effects of soy peptone on the inoculum preparation of Streptococcus zooepidemicus for production of hyaluronic acid. Bioresour. Technol., 130: 798-800.
CrossRef | Direct Link | - Severino, P., T. Andreani, A.S. Macedo, J.F. Fangueiro, M.H.A. Santana, A.M. Silva and E.B. Souto, 2012. Current state-of-art and new trends on lipid nanoparticles (SLN and NLC) for oral drug delivery. J. Drug Delivery. 10.1155/2012/750891.
CrossRef | Direct Link | - Severino, P., S.C. Pinho, E.B. Souto and M.H.A. Santana, 2012. Crystallinity of Dynasan® 114 and Dynasan® 118 matrices for the production of stable Miglyol®-loaded nanoparticles. J. Thermal Anal. Calorimetry, 108: 101-108.
CrossRef | Direct Link | - Severino, P., M.H.A. Santana and E.B. Souto, 2012. Optimizing SLN and NLC by 22 full factorial design: Effect of homogenization technique. Mater. Sci. Eng.: C, 32: 1375-1379.
CrossRef | Direct Link | - Severino, P., L.F. Moraes, B. Zanchetta, E.B. Souto and M.H.A. Santana, 2012. Elastic liposomes containing benzophenone-3 for sun protection factor enhancement. Pharmaceut. Dev. Technol., 17: 661-665.
CrossRef | Direct Link | - Severino, P., H. Silva, E.B. Souto, M.H.A. Santana and T.C.T. Dalla Costa, 2012. Analysis of in vivo absorption of didanosine tablets in male adult dogs by HPLC. J. Pharmaceut. Anal., 2: 29-34.
CrossRef | Direct Link | - Severino, P., G.G. de Oliveira, H.G. Ferraz, E.B. Souto and M.H.A. Santana, 2012. Preparation of gastro-resistant pellets containing chitosan microspheres for improvement of oral didanosine bioavailability. J. Pharmaceut. Anal., 2: 188-192.
CrossRef | Direct Link | - Rosada, R.S., C.L. Silva, M.H.A. Santana, C.R. Nakaie and L.G. de la Torre, 2012. Effectiveness, against tuberculosis, of pseudo-ternary complexes: Peptide-DNA-cationic liposome. J. Colloid Interface Sci., 373: 102-109.
CrossRef | Direct Link | - Motta, F.L. and M.H.A. Santana, 2012. Biomass production from Trichoderma viride in nonconventional oat medium. Biotechnol. Prog., 28: 1245-1250.
CrossRef | Direct Link | - De Paula Rigoletto, T., C.L. Silva, M.H.A. Santana, R.S. Rosada and L.G. de la Torre, 2012. Effects of extrusion, lipid concentration and purity on physico-chemical and biological properties of cationic liposomes for gene vaccine applications. J. Microencapsulation, 29: 759-769.
CrossRef | Direct Link | - De Macedo, A.C. and M.H.A. Santana, 2012. Hyaluronic acid depolymerization by ascorbate-redox effects on solid state cultivation of Streptococcus zooepidemicus in cashew apple fruit bagasse. World J. Microbiol. Biotechnol., 28: 2213-2219.
CrossRef | Direct Link | - Bicudo, R.C.S. and M.H.A. Santana, 2012. Production of Hyaluronic Acid (HA) nanoparticles by a continuous process inside microchannels: Effects of non-solvents, organic phase flow rate and HA concentration. Chem. Eng. Sci., 84: 134-141.
CrossRef | Direct Link | - Bicudo, R.C.S. and M.H.A. Santana, 2012. Effects of organic solvents on hyaluronic acid nanoparticles obtained by precipitation and chemical crosslinking. J. Nanosci. Nanotechnol., 12: 2849-2857.
CrossRef | Direct Link | - Severino, P., S.C. Pinho, E.B. Souto and M.H. Santana, 2011. Polymorphism, crystallinity and hydrophilic-lipophilic balance of stearic acid and stearic acid-capric/caprylic triglyceride matrices for production of stable nanoparticles. Colloids Surf. B: Biointerfaces, 86: 125-130.
CrossRef | Direct Link | - Pires, A. and M.H.A. Santana, 2011. Rheological aspects of microbial hyaluronic acid. J. Applied Polym. Sci., 122: 126-133.
CrossRef | Direct Link | - De Paula Rigoletto, T., M.E.D. Zaniquelli, M.H.A. Santana and L.G. de la Torre, 2011. Surface miscibility of EPC/DOTAP/DOPE in binary and ternary mixed monolayers. Colloids Surf. B: Biointerfaces, 83: 260-269.
CrossRef | Direct Link | - Da Silva, C.F., P. Severino, F. Martins and M.H.A. Santana, 2011. Didanosine-loaded chitosan microspheres: Optimization of fabrication process. Latin Am. J. Pharm., 30: 1037-1040.
Direct Link | - Teixeira, Z., B. Zanchetta, B.A. Melo, L.L. Oliveira and M.H.A. Santana et al., 2010. Retinyl palmitate flexible polymeric nanocapsules: characterization and permeation studies. Colloids Surf. B: Biointerfaces, 81: 374-380.
CrossRef | Direct Link | - Pires, A.M.B., S.Y. Eguchi and M.H.A. Santana, 2010. The influence of mineral ions on the microbial production and molecular weight of hyaluronic acid. Applied Biochem. Biotechnol., 162: 2125-2135.
CrossRef | Direct Link | - Pires, A.M.B., A.C. Macedo, S.Y. Eguchi and M.H.A. Santana, 2010. Microbial production of hyaluronic acid from agricultural resource derivatives. Bioresour. Technol., 101: 6506-6509.
CrossRef | Direct Link | - Pires, A.M.B. and M.H.A. Santana, 2010. Metabolic effects of the initial glucose concentration on microbial production of hyaluronic acid. Applied Biochem. Biotechnol., 162: 1751-1761.
CrossRef | Direct Link | - De Souza, A.O.., C.L. Silva, N. Duran and M.H. Andrade-Santana, 2010. Antimycobacterial and cytotoxicity activities of free and liposome-encapsulated 3-(4'-bromo [1,1'-biphenyl-4-yl)-3-(4-bromo-phenyl)-N, N-dimethyl-2-propen-1-amine. Quimica Nova, 33: 871-874.
CrossRef | Direct Link | - Re, M.I., M.H.A. Santana and M.A. d'Davila, 2009. Encapsulation Technologies for Modifying Food Performance. In: Innovation in Food Engineering: New Techniques and Products, Passos, M.L. and C.P. Ribeiro (Eds.). Chapter 7, CRC Press, Boca Raton, FL., USA., ISBN-13: 9781420086065, pp: 224-275.
- De la Torre, L.G., R.S. Rosada, A.P.F. Trombone, F.G. Frantz, A.A. Coelho-Castelo, C.L. Silva and M.H.A. Santana, 2009. The synergy between structural stability and DNA-binding controls the antibody production in EPC/DOTAP/DOPE liposomes and DOTAP/DOPE lipoplexes. Colloids Surf. B: Biointerfaces, 73: 175-184.
CrossRef | Direct Link | - Da Silva, C.F., P. Severino, F. Martins, M.V. Chaud and M.H.A. Santana, 2009. The intestinal permeation of didanosine from granules containing microspheres using the everted gut sac model. J. Microencapsulation, 26: 523-528.
CrossRef | Direct Link | - Souza, P.R., C.R. Zarate-Blades, J.I. Hori, S.G. Ramos and D.S. Lima et al., 2008. Protective efficacy of different strategies employing Mycobacterium leprae heat-shock protein 65 against tuberculosis. Expert Opin. Biol. Therapy, 8: 1255-1264.
CrossRef | Direct Link | - Rosada, R.S., L.G. Torre, F.G. Frantz, A.P. Trombone and C.R. Zarate-Blades et al., 2008. Protection against tuberculosis by a single intranasal administration of DNA-hsp65 vaccine complexed with cationic liposomes. BMC Immunol., Vol. 9. 10.1186/1471-2172-9-38.
CrossRef | Direct Link | - Martins, F., S.C. Pinho, T.C. Zollner, R.L. Zollner, M. de Cuyper and M.H.A. Santana, 2008. Surface-modified magnetic colloids for affinity adsorption of immunoglobulins. J. Magnetism Magn. Mater., 320: 1867-1870.
CrossRef | Direct Link | - De Pinho, S.C., R.L. Zollner, M. De Cuyper and M.H.A. Santana, 2008. Adsorption of antiphospholipid antibodies on affinity magnetoliposomes. Colloids Surf. B: Biointerfaces, 63: 249-253.
CrossRef | Direct Link | - Torre, L.G., A.L. Carneiro, R.S. Rosada, C.L. Silva and M.H.A. Santana, 2007. A mathematical model describing the kinetic of cationic liposome production from dried lipid films adsorbed in a multitubular system. Braz. J. Chem. Eng., 24: 477-486.
CrossRef | Direct Link | - Da Silva, C.F., F. Martins and M.H.A. Santana, 2007. Adsorption isotherms of mucin on granules containing chitosan microspheres. Adsorption Sci. Technol., 25: 781-789.
CrossRef | Direct Link | - Zancanella, P., M.A. Pianovski, B.H. Oliveira, S. Ferman and G.C. Piovezan et al., 2006. Mitotane associated with cisplatin, etoposide, and doxorubicin in advanced childhood adrenocortical carcinoma: Mitotane monitoring and tumor regression. J. Pediatr. Hematol./Oncol., 28: 513-524.
CrossRef | Direct Link | - Oliveira, B.F., M.H.A. Santana and M.I. Re, 2006. Spray-dried chitosan microspheres as a pDNA carrier. Drying Technol., 24: 373-382.
CrossRef | Direct Link | - Milagre, H.M.s., C.D.f. Milagre, P.J.s. Moran, M.H.A. Santana and J.A.R. Rodrigues, 2006. Asymmetric bioreduction of ethyl 3-halo-2-oxo-4-phenylbutanoate by Saccharomyces cerevisiae immobilized in Ca-alginate beads with double gel layer. Org. Process Res. Dev., 10: 611-617.
CrossRef | Direct Link | - De Moraes, N., J. Ambrosio, C.A. de Magalhaes, E. Christine and W. Quintilio et al., 2006. Poly-lactide-co-glycolide microparticle sizes: A rational factorial design and surface response analysis. J. Nanosci. Nanotechnol., 6: 2403-2407.
CrossRef | Direct Link | - Pinto, L.M., L.F. Fraceto, M.H.A. Santana, T.A. Pertinhez, S. Oyama Jr. and E. de Paula, 2005. Physico-chemical characterization of benzocaine-β-cyclodextrin inclusion complexes. J. Pharmaceut. Biomed. Anal., 39: 956-963.
CrossRef | Direct Link | - Oliveira, B., M.H.A. Santana and M.I. Re, 2005. Spray-dried chitosan microspheres cross-linked with D, L-glyceraldehyde as a potential drug delivery system: Preparation and characterization. Braz. J. Chem. Eng., 22: 353-360.
CrossRef | Direct Link | - Ogrodowski, C.S., C.O. Hokka and M.H.A. Santana, 2005. Production of hyaluronic acid by Streptococcus. Applied Biochem. Biotechnol., 122: 753-761.
CrossRef | Direct Link | - Milagre, H.M., C.D. Milagre, P.J. Moran, M.H.A. Santana and J.A.R. Rodrigues, 2005. Reduction of ethyl benzoylformate mediated by Saccharomyces cerevisiae entrapped in alginate fibers with double gel layers in a continuously operated reactor. Enzyme Microb. Technol., 37: 121-125.
CrossRef | Direct Link | - Zanin, M.H., I.C. Torriani, R.L. Zollner and M.H. Santana, 2004. Physical characterization of surface-modified liposomes by incorporation of gangliosides designed for immunotherapies. Colloids Surf. A: Physicochem. Eng. Aspects, 251: 175-182.
CrossRef | Direct Link | - Pinto, L.M., R. Pereira, E. de Paula, G. de Nucci, M.H.A. Santana and J.L. Donato, 2004. Influence of liposomal local anesthetics on platelet aggregation in vitro. J. Liposome Res., 14: 51-59.
CrossRef | Direct Link | - Maia, J.L., M.H.A. Santana and M.I. Re, 2004. The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation process. Braz. J. Chem. Eng., 21: 1-12.
CrossRef | Direct Link | - De Cuyper, M., S. Lievens, G. Flo, M. Cokelaere, C. Peleman, F. Martins and M.H.A. Santana, 2004. Receptor-mediated biological responses are prolonged using hydrophobized ligands. Biosens. Bioelectron., 20: 1157-1164.
CrossRef | Direct Link | - De Cuyper, M., A. Crabbe, J. Cocquyt, P. Van der Meeren, F. Martins and M.H.A. Santana, 2004. PEGylation of phospholipids improves their intermembrane exchange rate. Phys. Chem. Chem. Phys., 6: 1487-1492.
CrossRef | Direct Link | - De Araujo, D.R., C.M. Cereda, G.B. Brunetto, L.M. Pinto, M.H.A. Santana and E. de Paula, 2004. Encapsulation of mepivacaine prolongs the analgesia provided by sciatic nerve blockade in mice. Can. J. Anesthesia, 51: 566-572.
CrossRef | Direct Link | - Carneiro, A.L. and M.H.A. Santana, 2004. Production of liposomes in a multitubular system useful for scaling up of processes. Prog. Colloid Polym. Sci., 128: 273-277.
CrossRef | Direct Link | - Cabral, E.C.M., R.L. Zollner and M.H.A. Santana, 2004. Preparation and characterization of liposomes entrapping allergenic proteins. Braz. J. Chem. Eng., 21: 137-146.
CrossRef | Direct Link | - Alves, G.P. and M.H.A. Santana, 2004. Phospholipid dry powders produced by spray drying processing: Structural, thermodynamic and physical properties. Powder Technol., 145: 139-148.
CrossRef | Direct Link | - Zollner, T.C.A., R.D.L. Zollner, M. De Cuyper and M.H.A. Santana, 2003. Adsorption of isotype "E" antibodies on affinity magnetoliposomes. J. Dispersion Sci. Technol., 24: 615-622.
CrossRef | Direct Link | - Soares, C.M., M.H.A. Santana, G.M. Zanin and H.F. de Castro, 2003. Covalent coupling method for lipase immobilization on controlled pore silica in the presence of nonenzymatic proteins. Biotechnol. Prog., 19: 803-807.
CrossRef | Direct Link | - Hasan, S.D., W. Gambale, R.L. Zollner and M.H. Santana, 2003. Fungi allergens produced by solid-state fermentation process. Applied Biochem. Biotechnol., 106: 403-412.
CrossRef | Direct Link | - Cabral, E.C.M., P.T. Hennies, C.R.D. Correia, R.L. Zollner and M.H.A. Santana, 2003. Preparation and characterization of diacetylene polymerized liposomes for detection of autoantibodies. J. Liposome Res., 13: 199-211.
CrossRef | Direct Link | - Biloti, D.N., M.H.A. Santana and F.B.T. Pessine, 2003. Lipid membrane with low proton permeability. Biochimica Biophysica Acta (BBA)-Biomembr., 1611: 1-4.
CrossRef | Direct Link | - Soares, C.M., H.F. De Castro, M.H.A. Santana and G.M. Zanin, 2002. Intensification of lipase performance for long-term operation by immobilization on controlled pore silica in presence of polyethylene glycol. Applied Biochem. Biotechnol., 98: 863-874.
CrossRef | Direct Link | - De Cuyper, M., M. Hodenius, Z.G. Lacava, R.B. Azevedo, M.D.F. da Silva, P.C. Morais and M.H.A. Santana, 2002. Attachment of water-soluble proteins to the surface of (magnetizable) phospholipid colloids via NeutrAvidin-derivatized phospholipids. J. Colloid Interface Sci., 245: 274-280.
CrossRef | Direct Link | - Rocha, F.M., S.C. de Pinho, R.L. Zollner and M.H.A. Santana, 2001. Preparation and characterization of affinity magnetoliposomes useful for the detection of antiphospholipid antibodies. J. Magnetism Magn. Mater., 225: 101-108.
CrossRef | Direct Link | - Moraes, A.M., P.T.V. Rosa, M.H.A. SANTANA and R.G. Carbonell, 2001. Microparticulated Agents for Neutron Capture Therapy. In: Microspheres, Microcapsules and Liposomes, Volume 3: Radiolabeled and Magnetic Particulates in Medicine and Biology, Arshady, R. (Ed.). Citus Book, London, UK., ISBN-13: 978-0953218738, pp: 362-391.
- Hennies, P.T., M.H. Santana and C.R. Correia, 2001. Synthesis of the diacetylenic phospholipids 1, 2-(10',12'-heptadecadiynoyl)-sn-glycero-3-phophatidylcholine and 1,2-(4',6'-tricosadiynoyl)-sn-glycero-3-phophatidylcholine. J. Braz. Chem. Soc., 12: 64-72.
CrossRef | Direct Link | - De Castro, A.R.B., P.T. Fonseca, J.G. Pacheco, J.C.V. Da Silva, E.G.L. Da Silva and M.H.A. Santana, 2001. L-edge inner shell spectroscopy of nanostructured Fe3O4. J. Magnetism Magn. Mater., 233: 69-73.
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