Dr. Hugo F. Miranda Guzman
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Dr. Hugo F. Miranda Guzman

Senior Lecturer
University of Chile, Chile


Highest Degree
Ph.D. in Pharmacology from Emory University, USA

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Biography

Dr. Hugo F. Miranda Guzman is currently working as Senior Lecturer of Pharmacology, School of Medicine, Universidad de Chile, Universidad Andres Bello, Santiago, Chile. He obtained his Ph.D. in Pharmacology from Emory University, Atlanta, Georgia, USA. He is also serving as referee of many journals. He has published 123 articles as well as 2 books contributed as writer/co-writer.

Area of Interest:

Pharmacology and Toxicology
100%
Immunopharmacology
62%
Neuropharmacology
90%
Inflammation
75%
Pharmacodynamics
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Miranda, H.F., V. Noriega, P. Zanetta, J.C. Prieto, J.C. Prieto-Rayo, N. Aranda and F. Sierralta, 2014. Isobolographic analysis of the opioid-opioid interactions in a tonic and a phasic mouse model of induced nociceptive pain. J. Biomed. Sci., Vol. 21. 10.1186/s12929-014-0062-6.
    CrossRef  |  Direct Link  |  
  2. Miranda, H.F., V. Noriega, R.J. Zepeda, F. Sierralta and J.C. Prieto, 2013. Systemic synergism between codeine and morphine in three pain models in mice. Pharmacol. Rep., 65: 80-88.
    PubMed  |  Direct Link  |  
  3. Miranda, H.F., V. Noriega, P. Zanetta and J.C. Prieto, 2013. Isobolographic analysis in mice of the interaction of gabapentin and nortriptyline in relieving orofacial pain. J. Orofac. Pain, 27: 361-366.
    Direct Link  |  
  4. Zepeda, R.J., R. Castillo, R. Rodrigo, J.C. Prieto and I. Aramburu et al., 2012. Effect of carvedilol and nebivolol on oxidative stress-related parameters and endothelial function in patients with essential hypertension. Basic Clin. Pharmacol. Toxicol., 111: 309-316.
    CrossRef  |  Direct Link  |  
  5. Miranda, H.F., V. Noriega, R.J. Zepeda, F. Sierralta and J.C. Prieto, 2012. Synergism between fentanyl and tramadol in tonic inflammatory pain: The orofacial formalin test. Inflammation, 35: 1132-1137.
    CrossRef  |  
  6. Miranda, H.F., V. Noriega and J.C. Prieto, 2012. Previous administration of naltrexone did not change synergism between paracetamol and tramadol in mice. Pharmacol. Biochem. Behav., 102: 72-76.
    CrossRef  |  Direct Link  |  
  7. Miranda, H.F., M.A. Romero and M.M. Puig, 2012. Antinociceptive and anti-exudative synergism between dexketoprofen and tramadol in a model of inflammatory pain in Fundam. Clin. Pharmacol., 26: 373-382.
    CrossRef  |  Direct Link  |  
  8. Miranda, H.F., V. Noriega, L. Olavarria, R.J. Zepeda, F. Sierralta and J.C. Prieto, 2011. Antinociception and Anti‐inflammation induced by simvastatin in algesiometric assays in mice. Basic Clin. Pharmacol. Toxicol., 109: 438-442.
    CrossRef  |  
  9. Miranda, H.F., V. Noriega, F. Sierralta and J.C. Prieto, 2011. Interaction between dexibuprofen and dexketoprofen in the orofacial formalin test in mice. Pharmacol. Biochem. Behav., 97: 423-427.
    CrossRef  |  Direct Link  |  
  10. Miranda, H.F., A. Romero and M.M. Puig, 2011. Synergy between dexketoprofen and tramadol in a model of inflammatory pain in mice. Fund. Clin. Pharmacol., 25: 551-558.
  11. Gonzalez, C., C. Zegpi, V. Noriega, J.C. Prieto and H.F. Miranda, 2011. Synergism between dexketoprofen and meloxicam in an orofacial formalin test was not modified by opioid antagonists. Pharmacol. Rep., 63: 433-440.
    CrossRef  |  Direct Link  |  
  12. Garcia, G.G., H.F. Miranda, V. Noriega, F. Sierralta and L. Olavarria et al., 2011. Antinociception induced by atorvastatin in different pain models. Pharmacol. Biochem. Behav., 100: 125-129.
    CrossRef  |  Direct Link  |  
  13. Arrau, S., C. Delporte, C. Cartagena, M. Rodriguez-Diaz and P. Gonzalez et al., 2011. Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice. J. Ethnopharmacol., 133: 164-167.
    CrossRef  |  PubMed  |  Direct Link  |  
  14. Romero, A., H.F. Miranda and M.M. Puig, 2010. Antinociceptive effects of morphine, fentanyl, tramadol and their combination, in morphine-tolerant mice. Pharmacol. Biochem. Behav., 97: 363-369.
    CrossRef  |  Direct Link  |  
  15. Romero, A., H.F. Miranda and M.M. Puig, 2010. Analysis of the opioid-opioid combinations according to the nociceptive stimulus in mice. Pharmacol. Res., 61: 511-518.
    CrossRef  |  Direct Link  |  
  16. Munoz, J., C. Navarro, V. Noriega, G. Pinardi and F. Sierralta et al., 2010. Synergism between COX-3 inhibitors in two animal models of pain. Inflammopharmacology, 18: 65-71.
    CrossRef  |  
  17. Zegpi, C., C. Gonzalez, G. Pinardi and H.F. Miranda, 2009. The effect of opioid antagonists on synergism between dexketoprofen and tramadol. Pharmacol. Res., 60: 291-295.
    CrossRef  |  
  18. Miranda, H.F., M.M. Puig, M.A. Romero and J.C. Prieto, 2009. Effects of tramadol and dexketoprofen on analgesia and gastrointestinal transit in mice. Fund. Clin. Pharmacol., 23: 81-88.
    CrossRef  |  
  19. Miranda, H.F., F. Sierralta and J.C. Prieto, 2009. Synergism between NSAIDs in the orofacial formalin test in mice. Pharmacol. Biochem. Behav., 92: 314-318.
    CrossRef  |  
  20. Miranda, H.F. and G. Pinardi, 2009. Lack of effect of naltrindole on the spinal synergism of morphine and non-steroidal anti-inflammatory drugs (NSAIDS). J. Physiol. Pharmacol., 60: 71-76.
    Direct Link  |  
  21. Miranda, H.F. and G. Pinardi, 2009. Lack of effect of naltrexone on the spinal synergism between morphine and non steroidal anti-inflammatory drugs. Pharmacol. Reports, 61: 268-274.
    Direct Link  |  
  22. Prieto, J.C., G. Pinardi, J. Zamorano, E. Larrain and R.J. Zepeda et al., 2008. Lack of effect of atorvastatin or pravastatin on the endothelium-dependent relaxation in segments of human vessels. Int. J. Pharmacol., 4: 208-212.
    CrossRef  |  Direct Link  |  
  23. Miranda, H.F., J.C. Prieto, M.M. Puig and G. Pinardi, 2008. Isobolographic analysis of multimodal analgesia in an animal model of visceral acute pain. Pharmacol. Biochem. Behav., 88: 481-486.
    CrossRef  |  Direct Link  |  
  24. Backhouse, N., C. Delporte, C. Apablaza, M. Fariasa and L. Goity et al., 2008. Antinociceptive activity of Buddleja globosa (matico) in several models of pain. J. Ethnopharmacol., 119: 160-165.
    CrossRef  |  
  25. Prieto, J.C., G. Pinardi, J. Zamorano, E. Larrain and C. Bermudez et al., 2007. [Modification of phenylephrine induced contraction of human vessel rings by L-arginine and L-arginine methyl ester]. Revista Medica de Chile, 135: 1231-1236, (In Spanish).
    PubMed  |  
  26. Miranda, H.F., M.M. Puig, C. Dursteler, J.C. Prieto and G. Pinardi, 2007. Dexketoprofen-induced antinociception in animal models of acute pain: Synergy with morphine and paracetamol. Neuropharmacology, 52: 291-296.
    CrossRef  |  Direct Link  |  
  27. Dursteler, C., H.F. Miranda, R. Poveda, A. Mases, E. Planas and M.M. Puig, 2007. Synergistic interaction between dexamethasone and tramadol in a murine model of acute visceral pain. Fund. Clin. Pharmacol., 21: 515-520.
    CrossRef  |  
  28. Delporte, C., N. Backhouse, V. Inostroza, M.C. Aguirre and N. Peredo et al., 2007. Analgesic activity of Ugni molinae(murtilla) in mice models of acute pain. J. ethnopharmacol., 112: 162-165.
    CrossRef  |  Direct Link  |  
  29. Miranda, H.F., M.M. Puig, J.C. Prieto and G. Pinardi, 2006. Synergism between paracetamol and nonsteroidal anti-inflammatory drugs in experimental acute pain. Pain, 121: 22-28.
    CrossRef  |  Direct Link  |  
  30. Prieto, J.C., M. Quevedo, H.F. Miranda and G. Pinardi, 2005. Hypotensive effect of dopamine: Synergism induced by fenoldopam or levodopa. Acta cardiol., 60: 253-257.
    Direct Link  |  
  31. Pinardi, G., J.C. Prieto and H.F. Miranda, 2005. Analgesic synergism between intrathecal morphine and cyclooxygenase-2 inhibitors in mice. Pharmacol. Biochem. Behav., 82: 120-124.
    CrossRef  |  Direct Link  |  
  32. Miranda, H.F., J.C. Prieto and G. Pinardi, 2005. Spinal synergy between nonselective cyclooxygenase inhibitors and morphine antinociception in mice. Brain Res., 1049: 165-170.
    CrossRef  |  
  33. Miranda, H.F., E. Silva and G. Pinardi, 2004. Synergy between the antinociceptive effects of morphine and NSAIDs. Can. J. Physiol. Pharmacol., 82: 331-338.
    CrossRef  |  PubMed  |  
  34. Miranda, H.F. and G. Pinardi, 2004. Isobolographic analysis of the antinociceptive interactions of clonidine with nonsteroidal anti-inflammatory drugs. Pharmacol. Res., 50: 273-278.
    CrossRef  |  
  35. Pinardi, G., F. Sierralta and H.F. Miranda, 2003. Atropine reverses the antinociception of nonsteroidal anti-inflammatory drugs in the tail-flick test of mice. Pharmacol. Biochem. Behav., 74: 603-608.
    PubMed  |  Direct Link  |  
  36. Miranda, H.F., I. Lemus and G. Pinardi, 2003. Effect of the inhibition of serotonin biosynthesis on the antinociception induced by nonsteroidal anti-inflammatory drugs. Brain Res. Bull., 61: 417-425.
    CrossRef  |  Direct Link  |  
  37. Pinardi, G., F. Sierralta and H.F. Miranda, 2002. Adrenergic mechanisms in antinociceptive effects of non steroidal anti-inflammatory drugs in acute thermal nociception in mice. Inflamm. Res., 51: 219-222.
    CrossRef  |  Direct Link  |  
  38. Miranda, H.F., J. Lopez, F. Sierralta, A. Correa and G. Pinardi, 2002. NSAID antinociception measured in a chemical and a thermal assay in mice. Pain Res. Manag., 6: 190-196.
    PubMed  |  Direct Link  |  
  39. Miranda, H.F., F. Sierralta and G. Pinardi, 2002. Neostigmine interactions with non steroidal anti‐inflammatory drugs. Br. J. pharmacol., 135: 1591-1597.
    CrossRef  |  
  40. Miranda, H.F., F. Sierralta and G. Pinardi, 2002. Carbachol interactions with nonsteroidal anti-inflammatory drugs. Can. J. Physiol. Pharmacol., 80: 1173-1179.
    PubMed  |  Direct Link  |  
  41. Pinardi, G., F. Sierralta and H.F. Miranda, 2001. Interaction between the antinociceptive effect of ketoprofen and adrenergic modulatory systems. Inflammation, 25: 233-239.
    CrossRef  |  
  42. Pesce, M.E., X. Acevedo, D. Bustamante, H.F. Miranda and G. Pinardi, 2001. Effects of Ketoconazole on oestrus cycle and convulsant action of pentylenetetrazol in mice. Pharmacol. toxicol., 89: 312-314.
    CrossRef  |  
  43. Miranda, H.F., F. Sierralta and G. Pinardi, 2001. An isobolographic analysis of the adrenergic modulation of diclofenac antinociception. Anesth. Analg., 93: 430-435.
    PubMed  |  Direct Link  |  
  44. Miranda, H.F. and P.G. Pharmacol, 2001. Interactions of prazosin with non-steroidal anti-inflammatory drugs. Rev. Commun., 11: 253-262.
  45. Lopez, J., A. Correa, H.F. Miranda and G. Pinardi, 2001. Nitric oxide modulation of noradrenergic neurotrasmission in the vas deferens of the rat. Pharmacol. Rev. Commun., 11: 143-148.
  46. Quevedo, M., J.C. Prieto, H.F. Miranda and G. Pinardi, 2000. Isobolographic analysis of the interaction between fenoldopam and levodopa on arterial blood pressure of the rat. J. Cardiovasc. Pharmacol., 36: 413-415.
    Direct Link  |  
  47. Pesce, M.E., X. Acevedo, D. Bustamante, H.F. Miranda and G. Pinardi, 2000. Progesterone and testosterone modulate the convulsant actions of pentylenetetrazol and strychnine in mice. Pharmacol. Toxicol., 87: 116-119.
    PubMed  |  
  48. Lopez, J., A. Correa, G. Pinardi and H.F. Miranda, 2000. Cholinergic receptor subtypes in the urinary bladder of the rat in situ. Pharmacol. Rev. Commun., 11: 65-70.