Biography

David Gonzalez was born in Montevideo, Uruguay in 1965. In his country he attended Universidad de la Repåblica where he achieved his Master´s degree in 1994. He then pursued graduate studies in the USA, and was awarded a Ph.D. from the University of Florida in 1999 in the complementary fields of organic chemistry and biocatalysis.

Dr. Gonzalez returned to Uruguay in 1999 and joined the Faculty of Universidad de la Repåblica. He has continued working in the boundary between biocatalysis and organic chemistry focusing the application of enzymes to the construction of chiral organic molecules. These topics are relevant to green chemistry and David Gonzalez has become involved in the field particularly in developing green alternatives amenable for developing and emerging countries.

In 2008, David Gonzalez was elected Chemistry Coordinator for PEDECIBA, a University and Government joint program for the development of basic science in Uruguay. As Chemistry Coordinator he has attended the General Assembly Meeting of IUPAC in 2009 in Glasgow where he participated as observer in the Green Chemistry Subcommittee. Dr. Gonzalez is actively involved in international cooperation. He collaborates with IFS as an adviser and participated as invited speaker in International Workshops organized jointly by IFS and OPCW in 2008 and 2010. As representative of the University in the National Authority of OPCW in Uruguay he has actively promoted the development of chemistry and promoted conferences, projects and scholarships in all fields of chemistry within the region and bilateral cooperation between Uruguay and South Africa. From 2013 to 2018 he served at the OPCW SAB and got involved in promoting green chemistry and studied the convergence of chemistry and biology in issues relevant to the OPCW. In 2014 he was elected representative of the Researchers at the central PEDECIBA council and in 2016 was appointed to preside the Central Committee for Continuous Education of his University. From 2017 to 2019 he worked as Director of Science and Knowledge at the Ministry of Education where he implemented several changes and a reformulation of the office. In March 2019 he was elected by researchers and students to be Academic Director of PEDECIBA for a four-year period with the mission to strength basic science research, graduate education and promote science literacy among the Uruguayan society. In 2021 he was appointed as full profesor of Organic Chemistry and designed responsible of the biocatalysis and Biotransformations Laboratory at Facultad de QuØmica.

Area of Interest:

Biomedical Sciences

100%

Organic Chemistry

62%

Chemistry

90%

Toxicology

75%

Biotransformation

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
55

Abstracts
0

Selected Publications

RodrØguez, P., D. Gonzalez and S.R. Giordano, 2023. Detection of Endophytes by Cultivation Method. In: Endophytic Microbes: Isolation, Identification, and Bioactive Potentials, Sankaranarayanan, A., N. Amaresan and M.K. Dwivedi (Eds.), Humana, New York, ISBN: 978-1-0716-2826-3, pp: 33-42.
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Gonzalez, D., E. Botto, S.R. Giordano and P.R. Bonnecarrere, 2023. Screening of Endophytes for Biocatalytic Tools. In: Endophytic Microbes: Isolation, Identification, and Bioactive Potentials, Sankaranarayanan, A., N. Amaresan and M.K. Dwivedi (Eds.), Humana, New York, ISBN: 978-1-0716-2826-3, pp: 193-208.
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Sovera, V., S. MartØnez, D. Umpierrez, M.A. Vila, D. Gonzalezet al., 2022. Synthesis of azido-dienediols by enzymatic dioxygenation of benzylazides: An experimental and theoretical study. European. J. Organic. Chem., Vol. 2022. 10.1002/ejoc.202101156.
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Schapiro, V., M. Brovetto, I. Carrera, D. Gamenara, D. GonzÌlez, E. Pandolfi and G. Seoane, 2022. Achievements, challenges, and scope of thirty years of work on the biotransformation of arenes and their synthetic applications. Asian J. Org. Chem., Vol. 11. 10.1002/ajoc.202200530.
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Timperley, C.M., J.E. Forman, M. Abdollahi, A.S. Al-Amri and A. Bauliget al., 2021. Advice on assistance and protection provided by the scientific advisory board of the organisation for the prohibition of chemical weapons: Part 3. On medical care and treatment of injuries from sulfur mustard. Toxicology, Vol. 463. 10.1016/j.tox.2021.152967.
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Timperley, C.M., M. Abdollahi, A.S. Al-Amri, A. Baulig and D. Benachouret al., 2019. Advice on assistance and protection by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 2. On preventing and treating health effects from acute, prolonged, and repeated nerve agent exposure, and the identification of medical countermeasures able to reduce or eliminate the longer term health effects of nerve agents. Toxicology, 413: 13-23.
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Vitelio, C., A. Bellomo, M. Brovetto, G. Seoane and D. Gonzalez, 2004. Concise chemoenzymatic synthesis of epi-inositol. Carbohydr. Res., 339: 1773-1778.
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T. Hudlicky, U. Rinner, D. Gonzalez, H. Akgun, S. Schilling et al., 2003. Total synthesis and biological evaluation of amaryllidaceae alkaloids: Narciclasine, ent-7-deoxypancratistatin, regioisomer of 7-deoxypancratistatin, 10b-epi-deoxypancratistatin, and truncated derivatives. J. Org. Chem., 68: 674-674.
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Hudlicky, T., U. Rinner, D. Gonzalez, H. Akgun and S. Schilling et al., 2002. Total synthesis and biological evaluation of Amaryllidaceae Alkaloids: Narciclasine, ent-7-Deoxypancratistatin, Regioisomer of 7-Deoxypancratistatin, 10b-epi-Deoxypancratistatin, and truncated derivatives¹. J. Org. Chem., 67: 8726-8743.
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Reddy, G.D., O. Wiest, T. Hudlicky, V. Schapiro and D. Gonzalez, 1999. Electron transfer catalyzed [2 + 2] cycloreversion of benzene dimers. J. Org. Chem., 64: 2860-2863.
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Gonzalez, D., T. Martinot and T. Hudlicky, 1999. A short chemoenzymatic synthesis of (+)-narciclasine. Tetrahedron Lett., 40: 3077-3080.
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Hudlicky, T., D. Gonzalez, M. Stabile, M.A.A. Endoma and M. Deluca et al., 1998. New metabolites from the microbial oxidation of fluorinated aromatic compounds. J. Fluorine Chem., 89: 23-30.
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Butora, G., 1998. Toward a practical synthesis of morphine. The first several generations of a radical cyclization approach. Synthesis, 1998: 665-681.
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Gonzalez, D., V. Schapiro, G. Seoane, T. Hudlicky and K. Abboud, 1997. Chemoenzymatic synthesis of unnatural amino acids via modified claisen rearrangement of glycine enolates. Approach to morphine synthesis. J. Org. Chem., 62: 1194-1195.
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Gonzalez, D., V. Schapiro, G. Seoane and T. Hudlicky, 1997. New metabolites from toluene dioxygenase dihydroxylation of oxygenated biphenyls. Tetrahedron: Asymmetry, 8: 975-977.
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