Dr. Zainul Amiruddin Zakaria
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Dr. Zainul Amiruddin Zakaria

Senior Lecturer
Universiti Putra Malaysia, Malaysia


Highest Degree
Ph.D. in Pharmacology from Universiti Putra Malaysia, Malaysia

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Area of Interest:

Pharmacology and Toxicology
100%
Pharmacology
62%
Anti Inflammatory
90%
Anti-Cancer
75%
Anti Ulcer
55%

Research Publications in Numbers

Books
0
Chapters
3
Articles
219
Abstracts
0

Selected Publications

  1. Zakaria, Z.A., M.H.A. Rahim, M.H.M. Sani, M.H. Omar, S.M. Ching, A.A. Kadir and Q.U. Ahmed, 2019. Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway. BMC Complement. Altern. Med., Vol. 19. 10.1186/s12906-019-2486-8.
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  2. Taha, M., F. Rahim, M. Ali, M.N. Khan and M.A. Alqahtani et al., 2019. Synthesis of chromen-4-one-oxadiazole substituted analogs as potent β-glucuronidase inhibitors. Molecules, Vol. 24. 10.3390/molecules24081528.
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  3. Roheem, F.O., M. Soad, S. Zaiton, Q.U. Ahmed, S.A.A. Shah, J. Latip and Z.A. Zakaria, 2019. Evaluation of the enzyme inhibitory and antioxidant activities of Entada spiralis stem bark and isolation of the active constituents. Molecules, Vol. 24. 10.3390/molecules24061006.
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  4. Marmaya, N.H., Z.A. Zakaria and M.N.M. Desa, 2019. Gen Y consumers’ intention to purchase Halal food in Malaysia: A PLS-SEM approach. J. Islamic Market. 10.1108/JIMA-08-2018-0136.
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  5. Chin, V.K., A.M.Y. Asyran, Z.A. Zakaria, W.O. Abdullah and P.P. Chong et al., 2019. TREM-1 modulation produces positive outcome on the histopathology and cytokines release profile of Plasmodium berghei-infected mice. J. Parasitic Dis., 43: 139-153.
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  6. Almandil, N.B., M. Taha, R.K. Farooq, A. Alhibshi and M. Ibrahim et al., 2019. Synthesis of thymidine phosphorylase inhibitor based on quinoxaline derivatives and their molecular docking study. Molecules, Vol. 24. 10.3390/molecules24061002.
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  7. Zarizal, S., C.C. Yeo, G.M. Faizal, C.H. Chew and Z.A. Zakaria et al., 2018. Nasal colonisation, antimicrobial susceptibility and genotypic pattern of Staphylococcus aureus among agricultural biotechnology students in Besut, Terengganu, east coast of Malaysia. Trop. Med. Int. Health, 23: 905-913.
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  8. Zakaria, Z.A., M.H.A. Rahim, R.A.J. Roosli, M.H.M. Sani and M.H. Omar et al., 2018. Antinociceptive activity of methanolic extract of Clinacanthus nutans leaves: Possible mechanisms of action involved. Pain Res. Manage., Vol. 2018. 10.1155/2018/9536406.
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  9. Tohid, S.F.M., Z.A. Zakaria, A.A. Baharuddin and R.A.J. Roosli, 2018. Dicranopteris linearis extract inhibits the proliferation of human breast cancer cell lines (MDA-MB-231) via induction of S-phase arrest and apoptosis. Pharm. Biol., 56: 422-432.
  10. Salehi, B., S. Albayrak, H. Antolak, D. Kregiel and E. Pawlikowska et al., 2018. Aloe genus plants: From farm to food applications and phytopharmacotherapy. Int. J. Mol. Sci., Vol. 19.Aloe genus plants: From farm to food applications and phytopharmacotherapy. Int. J. Mol. Sci., Vol. 19. 10.3390/ijms19092843.
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  11. Nordin, M.L., A.A. Kadir, Z.A. Zakaria, R. Abdullah and M.N.H. Abdullah, 2018. In vitro investigation of cytotoxic and antioxidative activities of Ardisia crispa against breast cancer cell lines, MCF-7 and MDA-MB-231. BMC Complement. Alter. Med., Vol. 18. 10.1186/s12906-018-2153-5.
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  12. Khan, M.S.A., N. Ahmed, M. Arifuddin, Z.A. Zakaria and M.M. Al-Sanea et al., 2018. Anti-nociceptive mechanisms of flavonoids-rich methanolic extract from Terminalia coriacea (Roxb.) Wight & Arn. leaves. Food Chem. Toxicol., 115: 523-531.
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  13. Bello, R.O., V.K. Chin, M.F.A.R. Isnadi, R. Abd Majid and M.A. Abdullah et al., 2018. The role, involvement and function(s) of interleukin-35 and interleukin-37 in disease pathogenesis. Int. J. Mol. Sci., Vol. 19. 10.3390/ijms19041149.
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  14. Azemi, A.K., M.H.A. Rahim, S.S. Mamat, A.M.M. Jais and Z.A. Zakaria, 2018. Antiulcer activity of chloroform: methanol extract of Channa striatus fillet. Pak. J. Pharm. Sci., 31: 143-151.
  15. Zakaria, Z.A., N.D. Mahmood, S.S. Mamat, N. Nasir and M.H. Omar, 2017. Endogenous antioxidant and LOX-mediated systems contribute to the hepatoprotective activity of aqueous partition of methanol extract of Muntingia calabura L. leaves against paracetamol intoxication. Front. Pharmacol., Vol. 8. 10.3389/fphar.2017.00982.
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  16. Zakaria, Z.A., F.H. Kamisan, M.H. Omar, N.D. Mahmood, F. Othman, S.S.A. Hamid and M.N. Somchit, 2017. Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system. BMC Complement. Altern. Med., Vol. 17. 10.1186/s12906-017-1781-5.
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  17. Suhaimy, N.W.I., A.K.N. Azmi, N. Mohtarrudin, M.H. Omar and S.F.M. Tohid et al., 2017. Semipurified ethyl acetate partition of methanolic extract of Melastoma malabathricum leaves exerts gastroprotective activity partly via its antioxidant-antisecretory-anti-inflammatory action and synergistic action of several flavonoid-based compounds. Oxidat. Med. Cell. Longevity, Vol. 2017. 10.1155/2017/6542631.
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  18. Sharifi-Rad, M., E. Varoni, B. Salehi, J. Sharifi-Rad and K. Matthews et al., 2017. Plants of the genus Zingiber as a source of bioactive phytochemicals: From tradition to pharmacy. Molecules, Vol. 22. 10.3390/molecules22122145.
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  19. Pung, H.P., N.M. Azis, A.R. Abdul Rachman, T.Z.M.T. Jamaluddin and S.A. Nordin et al., 2017. Presence of methicillin resistance and heteroresistance among coagulase negative staphylococci (CoNS) isolates obtained from health sciences students at a public university. Trop. Biomed., 34: 84-88.
  20. Nordin, M.L., A. Abdul Kadir, Z.A. Zakaria, F. Othman, R. Abdullah and M.N.H. Abdullah, 2017. Cytotoxicity and apoptosis induction of Ardisia crispa and its solvent partitions against Mus musculus mammary carcinoma cell line (4T1). Evidence-Based Complement. Alter. Med., Vol. 2017. 10.1155/2017/9368079.
    CrossRef  |  
  21. Nasir, N.L.M., N.E. Kamsani, N. Mohtarrudin, F. Othman, S.F.M. Tohid and Z.A. Zakaria, 2017. Anticarcinogenic activity of Muntingia calabura leaves methanol extract against the azoxymethane-induced colon cancer in rats involved modulation of the colonic antioxidant system partly by flavonoids. Pharm. Biol., 55: 2102-2109.
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  22. Moshawih, S., M.S. Cheema, Z. Ahmad, Z.A. Zakaria and M.N. Hakim, 2017. A comprehensive review on Cosmos caudatus (Ulam Raja): Pharmacology, ethnopharmacology and phytochemistry. Int. Res. J. Educ. Sci., 1: 14-31.
  23. Jarrar, Q.B., M.N. Hakim, M.S. Cheema and Z.A. Zakaria, 2017. Comparative utrastructural hepatic alterations induced by free and liposome-encapsulated mefenamic acid. Ultrastruct. Pathol., 41: 335-345.
  24. Jarrar, Q.B., A. Zuraini, A. Abdul Kadir, Z.A. Zakaria and M.N. Hakim, 2017. Liposome encapsulation: A promising approach to enhance and safe mefenamic acid therapy. Int. Res. J. Educ. Sci., 1: 32-41.
  25. Jamila, N., N. Khan, A.A. Khan, I. Khan and S.N. Khan et al., 2017. In vivo carbon tetrachloride-induced hepatoprotective and in vitro cytotoxic activities of Garcinia hombroniana (seashore mangosteen). Afr. J. Tradit. Complement. Altern. Med., 14: 374-382.
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  26. Hasan, M.M., Q.U. Ahmed, S.Z.M. Soad, M. Taher and J. Latip et al., 2017. Flavonoids from Tetracera indica Merr. induced adipocyte differentiation and exert glucose uptake activities in 3T3-L1 adipocyte cells. BMC Complement. Altern. Med., Vol. 17. 10.1186/s12906-017-1929-3.
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  27. Hamidon, H., D. Susanti, M. Taher and Z.A. Zakaria, 2017. Garcinia atroviridis-A review on phytochemicals and pharmacological properties. Marmara Pharm. J., 21: 38-47.
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  28. Halim, S.Z., Z.A. Zakaria, M.H. Omar, N. Mohtarrudin, I.R. Abdul Wahab and M.N.H. Abdullah, 2017. Synergistic gastroprotective activity of methanolic extract of a mixture of Melastoma malabathricum and Muntingia calabura leaves in rats. BMC Complement. Altern. Med., Vol. 17. 10.1186/s12906-017-1992-9.
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  29. Deny, S., N. Attoumani, M. Taher, M.F. Rezali, M.H. Sohrab, C.M. Hasan and Z.A. Zakaria, 2017. A conformational isomer of soulattrolide from the stem bark of Calophyllum symingtonianum and its antibacterial activity. Nat. Prod. Sci., 24: 47-53.
  30. Azis, H.A., M. Taher, A.S. Ahmed, W.M.A.W. Sulaiman, D. Susanti, S.R. Chowdhury and Z.A. Zakaria, 2017. In vitro and in vivo wound healing studies of methanolic fraction of Centella asiatica extract. S. Afr. J. Bot., 108: 163-174.
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  31. Zakaria, Z.A., T. Balan, A.K. Azemi, M.H. Omar and N. Mohtarrudin et al., 2016. Mechanism(s) of action underlying the gastroprotective effect of ethyl acetate fraction obtained from the crude methanolic leaves extract of Muntingia calabura. BMC Complement. Altern. Med., Vol. 16. 10.1186/s12906-016-1041-0.
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  32. Zakaria, Z.A., M.H.M. Sani, A. Abdul Kadir, T.L. Kek and M.Z. Salleh, 2016. Antinociceptive effect of semi-purified petroleum ether partition of Muntingia calabura leaves. Rev. Bras. Farmacogn., 26: 408-419.
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  33. Zakaria, Z.A., M.H. Abdul Rahim, N. Motaruddin, A.K. Arifah, M.S. Cheema, A. Zuraini and S.F.M. Tohid, 2016. Acute and subchronic oral toxicity studies of methanol extract of Clinacanthus nutans Lindau in mice. Afr. J. Tradit. Complement. Altern. Med., 13: 210-222.
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  34. Zakaria, Z.A., F. Yahya, S.S. Mamat, N.D. Mahmood and N. Mohtarrudin et al., 2016. Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: Involvement of the antioxidant mechanisms. BMC Complement. Altern. Med., Vol. 16. 10.1186/s12906-016-1110-4.
    CrossRef  |  
  35. Zakaria, Z.A., E.S. Jaios, M.H. Omar, S. Abd. Rahman and S.S.A. Hamid et al., 2016. Antinociception of semi-purified petroleum ether partition derived from crude methanol extract of Melastoma malabathricum leaves and its possible mechanisms of action in animal models. BMC Complement. Altern. Med., Vol. 16. 10.1186/s12906-016-1478-1.
    CrossRef  |  
  36. Zakaria, Z.A., A.S.N. Zainol, A. Sahmat, N.I. Salleh and A. Hizami et al., 2016. Gastroprotective activity of chloroform extract of Muntingia calabura and Melastoma malabathricum leaves extracts. Pharm. Biol., 54: 812-826.
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  37. Wan Zainulddin, N.W., Z. Zabidi, F.H. Kamisan, F. Yahya and N.A. Ismail et al., 2016. Anti-ulcer activity of the aqueous extract of Melastoma malabathricum L. leaf in rats. Pak. J. Pharm. Sci., 29: 35-38.
    Direct Link  |  
  38. Taher, M., T.M. Zakaria, D. Susanti and Z.A. Zakaria, 2016. Hypoglycaemic activity of ethanolic extract of Garcinia mangostana Linn. in normoglycaemic and streptozotocin-induced diabetic rats. BMC Complementary Alter. Med., Vol. 16. 10.1186/s12906-016-1118-9.
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  39. Selverajah, M., Z.A. Zakaria, K. Long, Z. Ahmad, A. Yaacob and M.N. Somchit, 2016. Anti-ulcerogenic activity of virgin coconut oil contribute to the stomach health of humankind. Tang, 6: 12-18.
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  40. Messaoudi, D., H. Bouriche, S.S. Mamat, A. Senator and Z.A. Zakaria, 2016. Evaluation of hepatoprotective effect of Algerian Santolina chamaecyparissus against acute exposure to paracetamol. Der Pharm. Lett., 8: 1-7.
  41. Jaios, E.S., S. Abdul Rahman, S.M. Ching, A.K. Arifah, M.N. Desa and Z.A. Zakaria, 2016. Mechanisms of antinociceptive activity exerted by orally administered methanol extract of Melastoma malabathricum leaves. Braz. J. Pharmacogn., 26: 586-594.
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  42. Hamidon, H., M. Taher, J.M. Jaffri, T.M.F.S.T. Zakaria and W.M.A. Wan Sulaiman et al., 2016. Cytotoxic and anti-inflammatory activities of Garcinia xanthochymus extracts on cell lines. Makara J. Health Res., 20: 11-17.
  43. Dyary, H.O., A.K. Arifah, R.S.K. Sharma, A. Rasedee and M.S. Aspollah et al., 2016. Acute toxicological assessment of seashore mangosteen (Garcinia hombroniana) aqueous extract. J. Vet. Malaysia, 28: 4-11.
    Direct Link  |  
  44. Ching, S.M., V. Ramachandran, L.T. Gew, S.M.S. Lim and W.A. Wan Sulaiman et al., 2016. Complementary alternative medicine use among patients with dengue fever in the hospital setting: A cross-sectional study in Malaysia. BMC Complement. Altern. Med., Vol. 16. 10.1186/s12906-016-1017-0.
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  45. Abdul Rahim, M.H., Z.A. Zakaria, M.H. Mohd Sani, M.H. Omar and Y. Yakob et al., 2016. Methanolic extract of Clinacanthus nutans exerts antinociceptive activity via the opioid/nitric oxide-mediated, but cGMP-independent, pathways. Evidence-Based Complement. Alter. Med. 10.1155/2016/1494981.
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  46. Zakaria, Z.A., T. Balan, S.S. Mamat, N. Mohtarrudin, T.L. Kek and M.Z. Salleh, 2015. Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves. BMC Complement. Altern. Med., Vol. 15. 10.1186/s12906-015-0638-z.
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  47. Taher, M., M.Z.A.M. Amiroudine, T.M.F.S.T. Zakaria, D. Susanti and S.J.A. Ichwan et al., 2015. α-Mangostin improves glucose uptake and inhibits adipocytes differentiation in 3T3-L1 cells via PPARγ, GLUT4 and leptin expressions. Evidence-Based Complement. Altern. Med., Vol. 2015. 10.1155/2015/740238.
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  48. Selvarajah, M., Z. Ahmad, Z.A. Zakaria, H.S. Chiong, Y.K. Yong, K. Long and M.N. Hakim, 2015. Comparative investigation into the anti-ulcer activity of virgin coconut oil and coconut oil in pylorous ligated animal model. TANG: Humanitas Med., Vol. 5, No. 4. 10.5667/tang.2015.0030.
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  49. Sani, M.H.M., M. Taher, D. Susanti, T.L. Kek, M.Z. Salleh and Z.A. Zakaria, 2015. Mechanisms of α-mangostin-induced antinociception in a rodent model. Biol. Res. Nursing, 17: 68-77.
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  50. Safren, S.R., A.R. Abdul Rachman, Y.K. Cheah, Z.A. Zakaria, Z. Suhaili, N. Mohd Taib and M.N.M. Desa, 2015. Comparative phenotypic and genotypic properties of Pseudomonas aeruginosa isolates from clinical and environmental sources. Asia Pacific Environ. Occup. Health J., 1: 54-61.
  51. Rofiee, M.S., M.I.M. Yusof, E. Abdul Hisam, Z. Bannur and Z.A. Zakaria et al., 2015. Isolating the metabolic pathways involved in the hepatoprotective effect of Muntingia calabura against CCl4-induced liver injury using LC/MS Q-TOF. J. Ethnopharmacol., 166: 109-118.
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  52. Fong, L.Y., C.T. Ng, Z.A. Zakaria, M.T.H. Baharuldin, A.K. Arifah, M.N. Hakim and A. Zuraini, 2015. Asiaticoside inhibits TNF-α-induced endothelial hyperpermeability of human aortic endothelial cells. Phytother. Res., 29: 1501-1508.
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  53. Dyary, H.O., A.K. Arifah, R.S.K. Sharma, A. Rasedee and M.M. Aspollah et al., 2015. In vivo antitrypanosomal activity of Garcinia hombroniana aqueous extract. Res. Vet. Sci., 100: 226-231.
    CrossRef  |  Direct Link  |  
  54. Balan, T., M.H.M. Sani, S.H.M. Ahmad, V. Suppaiah, N. Mohtarrudin and Z.A. Zakaria, 2015. Antioxidant and anti-inflammatory activities contribute to the prophylactic effect of semi-purified fractions obtained from the crude methanol extract of Muntingia calabura leaves against gastric ulceration in rats. J. Ethnopharmacol., 164: 1-15.
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  55. Azis, H.A., M. Taher, D. Susanti and Z.A. Zakaria, 2015. In vitro wound healing activity of Sapium indicum willd leaf extracts. Afr. J. Tradit. Complement. Altern. Med., 12: 126-132.
    CrossRef  |  Direct Link  |  
  56. Zakaria, Z.A., T. Balan, V. Suppaiah, S. Ahmad and F. Jamaludin, 2014. Mechanism(s) of action involved in the gastroprotective activity of Muntingia calabura. J. Ethnopharmacol., 151: 1184-1193.
    CrossRef  |  Direct Link  |  
  57. Zakaria, Z.A., M.H.M. Sani, M.S. Cheema, A.A. Kader, T.L. Kek and M.Z. Salleh, 2014. Antinociceptive activity of methanolic extract of Muntingia calabura leaves: Further elucidation of the possible mechanisms. BMC Complementary Altern. Med., Vol. 14. 10.1186/1472-6882-14-63.
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  58. Teh, L.K., Z. Bannur, Z.A. Zakaria, H.M.H. Fazleen and M.Z. Salleh, 2014. Single Nucleotide Polymorphism (SNPs) analysis of mu-opioid receptors (OPRM1) using Denaturing High Performance Liquid Chromatography (DHPLC) among the intravenous drug users. Int. J. Pharm. Pharmaceut. Sci., 6: 281-287.
    Direct Link  |  
  59. Somchit, M.N., N.A. Mohamed, Z. Ahmad, Z.A. Zakaria, L. Shamsuddin, M.S.O. Fauzee and A.A. Kadir, 2014. Anti-inflammatory and anti-pyretic properties of Spirulina platensis and Spirulina lonar: A comparative study. Pak. J. Pharm. Sci., 27: 1277-1280.
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  60. Mahmood, N.D., S.S. Mamat, F.H. Kamisan, F. Yahya and M.F.F. Kamarolzaman et al., 2014. Amelioration of paracetamol-induced hepatotoxicity in rat by the administration of methanol extract of Muntingia calabura L. leaves. BioMed Res. Int., Vol. 2014. 10.1155/2014/695678.
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  61. Mahmood, N.D., N.L.M. Nasir, M.S. Rofiee, S.F.M. Tohid and S.M. Ching et al., 2014. Muntingia calabura: A review of its traditional uses, chemical properties and pharmacological observations. Pharm. Biol., 52: 1598-1623.
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  62. Kooi, O.K., C.Y. Ling, R. Rodzi, F. Othman, N. Mohtarrudin, Z. Suhaili and Z.A. Zakaria, 2014. Chemopreventive activity of methanol extract of Melastoma malabathricum leaves in DMBA-induced mouse skin carcinogenesis. Afr. J. Tradit. Complement. Altern. Med., 11: 66-70.
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  63. Kamisan, F.H., F. Yahya, S.S. Mamat, M.F.F. Kamarolzaman and N. Mohtarrudin et al., 2014. Effect of methanol extract of Dicranopteris linearis against carbon tetrachloride-induced acute liver injury in rats. BMC Complement. Altern. Med., Vol. 14. 10.1186/1472-6882-14-123.
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  64. Kamarolzaman, M.F.F., F. Yahya, S.S. Mamat, K.F. Jakius and N.D. Mahmood et al., 2014. Gastroprotective activity and mechanisms of action of Bauhinia purpurea Linn (Leguminoseae) leaf methanol extract. Trop. J. Pharmaceut. Res., 13: 1889-1898.
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  65. Ismail, N.A., S. Din, N. Syafawati, S.S. Mamat and Z. Zabidi et al., 2014. Effect of aqueous extract of Dicranopteris linearis leaves against paracetamol and carbon tetrachloride-induced liver toxicity in rats. Pak. J. Pharm. Sci., 27: 831-835.
    Direct Link  |  
  66. Goh, J.Z., H.S. Chiong, A. Zuraini, A.K. Arifah and Z.A. Zakaria et al., 2014. Rapid spectrophotometric determination, characterization and anti-inflammatory efficacy evaluation of nanoencapsulated diclofenac sodium. J. Drug Deliv. Sci. Technol., 24: 361-366.
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  67. Dyary, H.O., A.K. Arifah, R.S. Sharma, A. Rasedee and M.S. Mohd-Aspollah et al., 2014. Antitrypanosomal screening and cytotoxic effects of selected medicinal plants. Trop. Biomed., 31: 89-96.
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  68. Bannur, Z., M.Z. Salleh, H. Hashim, T. Hennessy and M.N. Azmi et al., 2014. Metabolomics and pharmacogenetics based 5-fluorouracil monitoring in colorectal cancer patients. Int. J. Pharm. Pharmaceut. Sci., 6: 288-295.
  69. Bannur, Z., L.K. Teh, T. Hennesy, W.R.W. Rosli and N. Mohamad et al., 2014. The differential metabolite profiles of acute lymphoblastic leukaemic patients treated with 6-mercaptopurine using untargeted metabolomics approach. Clin. Biochem., 47: 427-431.
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  70. Balan, T., M.H.M. Sani, V. Suppaiah, N. Mohtarrudin, Z. Suhaili, Z. Ahmad and Z.A. Zakaria, 2014. Antiulcer activity of Muntingia calabura leaves involves the modulation of endogenous nitric oxide and nonprotein sulfhydryl compounds. Pharmaceut. Biol., 52: 410-418.
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  71. Zulkifli, M.H., L.K. Teh, L.S. Lee, Z.A. Zakaria and M.Z. Salleh, 2013. Draft genome sequence of Klebsiella pneumoniae isolate PR04. Genome Announc., Vol. 1, No. 4. 10.1128/genomeA.00418-13.
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  72. Zakaria, Z.A., M.H. Sani, M.F. Mohammat, N.S. Mansor and Z. Shaameri et al., 2013. Antinociceptive activity of a synthetic oxopyrrolidine-based compound, ASH21374 and determination of its possible mechanisms. Can. J. Physiol. Pharmacol., 91: 1143-1153.
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  73. Yusof, M.I.M., M.Z. Salleh, T.L. Kek, N. Ahmat, N.F.N. Azmin and Z.A. Zakaria, 2013. Activity-guided isolation of bioactive constituents with antinociceptive activity from Muntingia calabura L. leaves using the formalin test. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/715074.
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  74. Yong, Y.K., Z.A. Zakaria, A.A. Kadir, M.N. Somchit, G.E.C. Lian and Z. Ahmad, 2013. Chemical constituents and antihistamine activity of Bixa orellana leaf extract. BMC Complementary Altern. Med., Vol. 13. 10.1186/1472-6882-13-32.
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  75. Yong, Y.K., N. Sulaiman, M.N. Hakim, G.E.C. Lian, Z.A. Zakaria, F. Othman and Z. Ahmad, 2013. Suppressions of serotonin-induced increased vascular permeability and leukocyte infiltration by Bixa orellana leaf extract. BioMed Res. Int., Vol. 2013. 10.1155/2013/463145.
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  76. Yahya, F., S.S. Mamat, M.F.F. Kamarolzaman, A.A. Seyedan and K.F. Jakius et al., 2013. Hepatoprotective activity of methanolic extract of Bauhinia purpurea leaves against paracetamol-induced hepatic damage in rats. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/636580.
    CrossRef  |  Direct Link  |  
  77. Teh, L.K., S. Hamzah, H. Hashim, Z. Bannur and Z.A. Zakaria et al., 2013. Potential of dihydropyrimidine dehydrogenase genotypes in personalizing 5-fluorouracil therapy among colorectal cancer patients. Therapeut. Drug Monit., 35: 624-630.
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  78. Suhaili, Z.B., S.A. Johari, M.H. Sajili, A. Yahya, Z.A. Zakaria, M.N.M. Desa and A.M. Ali, 2013. In silico PCR verification and simplex real-time PCR detection of methicillin-resistant Staphylococcus aureus (MRSA) from east coast Malaysian clinical isolates. Walailak J. Sci. Technol. (WJST)., 10: 237-246.
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  79. Sufian, A.S., K. Ramasamy, N. Ahmat, Z.A. Zakaria and M.I.M. Yusof, 2013. Isolation and identification of antibacterial and cytotoxic compounds from the leaves of Muntingia calabura L. J. Ethnopharmacol., 146: 198-204.
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  80. Siew-Mooi, C., R. Vasudevan, Z.A. Zakaria and F. Paimin, 2013. Frequency of complementary and alternative medicine usage among Malaysian hypertensive subjects. Life Sci. J., 10: 2226-2231.
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  81. Seyyedan, A., F. Yahya, M.F.F. Kamarolzaman, Z. Suhaili and M.N.M. Desa et al., 2013. Review on the ethnomedicinal, phytochemical and pharmacological properties of Piper sarmentosum: Scientific justification of its traditional use. TANG: Humanitas Med., Vol. 3, No. 3. 10.5667/tang.2013.0002.
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  83. Raduan, S.Z., M.W.H. Abdul Aziz, A.H. Roslida, Z.A. Zakaria, A. Zuraini and M.N. Hakim, 2013. Anti-inflammatory effects of Hibiscus rosa-sinensis L. and Hibiscus rosa-sinensis var. alba ethanol extracts. Int. J. Pharm. Pharmaceut. Sci., 5: 754-762.
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  84. Mamat, S.S., M.F.F. Kamarolzaman, F. Yahya, N.D. Mahmood and M.S. Shahril et al., 2013. Methanol extract of Melastoma malabathricum leaves exerted antioxidant and liver protective activity in rats. BMC Complementary Altern. Med., Vol. 13. 10.1186/1472-6882-13-326.
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  86. Khalid, M.I.H., L.K. Teh, L.S. Lee, Z.A. Zakaria and M.Z. Salleh, 2013. Genome sequence of Proteus mirabilis strain PR03, isolated from a local hospital in Malaysia. Genome Announc., Vol. 1, No. 3. 10.1128/genomeA.00327-13.
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  88. Hamzah, S., L.K. Teh, J.S.K. Siew, G. Ahmad, H.S. Wong, Z.A. Zakaria and M.Z. Salleh, 2013. Pharmacogenotyping of CYP3A5 in predicting dose-adjusted trough levels of tacrolimus among Malaysian kidney-transplant patients. Can. J. Physiol. Pharmacol., 92: 50-57.
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  89. Goh, J.Z., S.N. Tang, A. Zuraini, Z.A. Zakaria and A.A. Kadir et al., 2013. Enhanced anti-inflammatory effects of nanoencapsulated diclofenac. Eur. J. Inflamm., 11: 855-861.
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  90. Chiong, H.S., Y.K. Yong, Z. Ahmad, M.R. Sulaiman, Z.A. Zakaria, K.H. Yuen and M.N. Hakim, 2013. Cytoprotective and enhanced anti-inflammatory activities of liposomal piroxicam formulation in lipopolysaccharide-stimulated RAW 264.7 macrophages. Int. J. Nanomed., 8: 1245-1255.
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  91. Ching, S.M., Z.A. Zakaria, F. Paimin and M. Jalalian, 2013. Complementary alternative medicine use among patients with type 2 diabetes mellitus in the primary care setting: A cross-sectional study in Malaysia. BMC Complement. Altern. Med., Vol. 13. 10.1186/1472-6882-13-148.
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  92. Adam, Y., A.A. Nasaruddin, A. Zuraini, A.K. Arifah, M.S.O. Fauzee, Z.A. Zakaria and M.N. Somchit, 2013. Diuretic activity of roots from Carica papaya L. and Ananas comosus L. Int. J. Pharmaceut. Sci. Rev. Res., 23: 163-167.
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  93. Zakaria, Z.A., N.H. Sodri, H. Hassan, K. Anuar and C.A. Fatimah, 2012. Effects of various receptor antagonists on the peripheral antinociceptive activity of aqueous extracts of Dicranopteris linearis, Melastoma malabathricum and Bauhinia purpurea leaves in mice. TANG: Humanitas Med., Vol. 2, No. 4. 10.5667/tang.2012.0017.
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  94. Zakaria, Z.A., M.K. Hussain, A.S. Mohamad, F.C. Abdullah and M.R. Sulaiman, 2012. Anti-inflammatory activity of aqueous extract of Ficus deltoidea. Biol. Res. Nurs., 14: 90-97.
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  95. Zakaria, Z.A., E.E. Abdul Hisam, M. Norhafizah, M.S. Rofiee, F. Othman, A.H. Hasiah and M. Vasudevan, 2012. Methanol extract of Bauhinia purpurea leaf possesses Anti-ulcer activity. Med. Principles Pract., 21: 476-482.
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  97. Yassir, M.A., A.K. Arifah, H. Yaakub, A. Zuraini, Z.A. Zakaria and M.N. Somchit, 2012. Effect of breed on cis-9, trans-11 and trans-10, cis-12 Conjugated Linoleic Acids (CLA) concentrations in milk fat of dairy cattle and the relationship of these CLA with other unsaturated C18 fatty acids. Pertanika J. Trop. Agric. Sci., 35: 165-172.
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  99. Teh, L.K., I.M. Langmia, M.H.F. Haslinda, H.A. Ngow and M.J. Roziah et al., 2012. Clinical relevance of VKORC1 (G-1639A and C1173T) and CYP2C9*3 among patients on warfarin. J. Clin. Pharm. Therapeut., 37: 232-236.
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  100. Teh, L.K., H. Hashim, Z.A. Zakaria and M.Z. Salleh, 2012. Polymorphisms of UGT1A1*6, UGT1A1*27 and UGT1A1*28 in three major ethnic groups from Malaysia. Indian J. Med. Res., 136: 249-259.
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  101. Teh, L.K., A.F. Izuddin, Z.A. Zakaria and M.Z. Salleh, 2012. Tridimensional personalities and polymorphism of dopamine D2 receptor among heroin addicts. Biol. Res. Nurs., 14: 188-196.
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  102. Tasrip, N.A., M.N.M. Desa, C.Y. Kqueen, N.Z.M. Zin and Z.A. Zakaria et al., 2012. A comparison between aerial mass colors, antibacterial activities and RAPD fingerprints of soil isolates of streptomyces. J. Biol. Sci., 12: 218-224.
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  103. Somchit, N., J.H. Chung, A. Yaacob, Z. Ahmad, Z.A. Zakaria and A.A. Kadir, 2012. Lack of hepato- and nephrotoxicity induced by antifungal drug voriconazole in laboratory rats. Drug Chem. Toxicol., 35: 304-309.
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  104. Somchit, M.N., J.H. Mak, A.A. Bustamam, A. Zuraini, A.K. Arifah, Y. Adam and Z.A. Zakaria, 2012. Zerumbone isolated from Zingiber zerumbet inhibits inflammation and pain in rats. J. Med. Plants Res., 6: 177-180.
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  105. Sani, M.H.M., Z.A. Zakaria, T. Balan, L.K. Teh and M.Z. Salleh, 2012. Antinociceptive activity of methanol extract of Muntingia calabura leaves and the mechanisms of action involved. Evidence-Based Complementary Altern. Med., Vol. 2012. 10.1155/2012/890361.
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  106. Pihie, L., A. Hawariah, Z.A. Zakaria and F. Othman, 2012. Antiproliferative and proapoptotic effects of Labisia pumila ethanol extract and its active fraction in human melanoma HM3KO cells. Evidence-Based Complement. Altern. Med., Vol. 2012. 10.1155/2012/123470.
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  107. Khan, M.S.A., A.M.M. Jais, Z.A. Zakaria, N. Mohtarruddin and M. Ranjbar et al., 2012. Wound healing potential of leathery Murdah, Terminalia coriacea (Roxb.) wight and ARN. Phytopharmacology, 3: 158-168.
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  108. Joffry, S.M., N.J. Yob, M.S. Rofiee, M.M.R.M.M. Affandi and F. Othman et al., 2012. Melastoma malabathricum (L.) Smith: A review of its ethnomedicinal, chemical and pharmacological uses. Evidence-Based Complement. Altern. Med., Vol. 2012. 10.1155/2012/258434.
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  109. Din, S.S., S.S. Mamat, N.A. Ismail, W.N.W. Zainulddin and Z. Zabidi et al., 2012. Effect of chloroform extract of traditional Dicranopteris linearis leaves against paracetamol- and CCl4-induced liver toxicity in rats. TANG: Humanitas Med., Vol. 2, No. 4. 10.5667/tang.2012.0026.
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  110. Ali, Y.M., A.A. Kadir, Z. Ahmad, H. Yaakub, Z.A. Zakaria and M.N.H. Abdullah, 2012. Free radical scavenging activity of conjugated linoleic acid as single or mixed isomers. Pharmaceut. Biol., 50: 712-719.
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  111. Abdul Hisam, E.E., Z.A. Zakaria, N. Mohtaruddin, M.S. Rofiee, H.A. Hamid and F. Othman, 2012. Antiulcer activity of the chloroform extract of Bauhinia purpurea leaf. Pharmaceut. Biol., 50: 1498-1507.
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  112. Zin, N.Z.M., N.A. Tasrip, M.N.M. Desa, C.Y. Kqueen, Z.A. Zakaria, R.A. Hamat and M.N. Shamsudin, 2011. Characterization and antimicrobial activities of two Streptomyces isolates from soil in the periphery of Universiti Putra Malaysia. Trop. Biomed., 28: 651-660.
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  113. Zakaria, Z.A., M.S. Rofiee, M.N. Somchit, A. Zuraini and M.R. Sulaiman et al., 2011. Hepatoprotective activity of dried- and fermented-processed virgin coconut oil. Evid.-Based Complement. Altern. Med., Vol. 2011. 10.1155/2011/142739.
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  114. Zakaria, Z.A., M.S. Rofiee, L.K. Teh, M.Z. Salleh, M.R. Sulaiman and M.N. Somchit, 2011. Bauhinia purpurea leaves' extracts exhibited in vitro antiproliferative and antioxidant activities. Afr. J. Biotechnol., 10: 65-74.
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  115. Zakaria, Z.A., M.S. Rofiee, A.M. Mohamed, L.K. The and M.Z. Salleh, 2011. In vitro antiproliferative and antioxidant activities and total phenolic contents of the extracts of Melastoma malabathricum leaves. J. Acupuncture Meridian Stud., 4: 248-256.
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  116. Zakaria, Z.A., M.N. Somchit, A.M. Jais, L.K. Teh, M.Z. Salleh and K. Long, 2011. In vivo antinociceptive and anti-inflammatory activities of dried and fermented processed virgin coconut oil. Med. Principles Pract., 20: 231-236.
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  117. Zakaria, Z.A., M.L. Zakaria, Z. Amom and M.N.M. Desa, 2011. Antimicrobial activity of the aqueous extract of selected Malaysian herbs. Afr. J. Microbiol. Res., 5: 5379-5383.
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  118. Zakaria, Z.A., E.E. Abdul Hisam, M.S. Rofiee, M. Norhafizah, M.N. Somchit, L.K. The and M.Z. Salleh, 2011. In vivo antiulcer activity of the aqueous extract of Bauhinia purpurea leaf. J. Ethnopharmacol., 137: 1047-1054.
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  119. Zakaria, Z.A., A.M. Mohamed, N.S.M. Jamil, M.S. Rofiee and M.N. Somchit et al., 2011. In vitro cytotoxic and antioxidant properties of the aqueous, chloroform and methanol extracts of Dicranopteris linearis Leaves. Afr. J. Biotechnol., 10: 273-282.
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  120. Zakaria, Z.A., A.M. Mohamed, N.M. Jamil, M.S. Rofiee and M.K. Hussain et al., 2011. In vitro antiproliferative and antioxidant activities of the extracts of Muntingia calabura leaves. Am. J. Chin. Med., 39: 183-200.
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  121. Yob, N.J., S.M. Jofrry, M.M. Affandi, L.K. Teh, M.Z. Salleh and Z.A. Zakaria, 2011. Zingiber zerumbet (L.) smith: A review of its ethnomedicinal, chemical and pharmacological uses. Evidence-Based Complement. Altern. Med., Vol. 2011. 10.1155/2011/543216.
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  122. Teh, L.K., S.H.M. Dom, Z.A. Zakaria and M.Z. Salleh, 2011. A systematic review of the adverse effects of tacrolimus in organ transplant patients. Afr. J. Pharm. Pharmacol., 5: 764-771.
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  123. Suhaili, Z., C.C. Yeo, H.N. Yasin, N.A. Badaludin and Z.A. Zakaria, 2011. Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria. Afr. J. Microbiol. Res., 5: 5147-5154.
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  124. Somchit, M.N., Y. Adam, H.C. Yee, A. Zuraini, A.K. Arifah and Z.A. Zakaria, 2011. Anti-fungal activity of Ardisia crispa (Thunb.) A. DC. against several fungi responsible for athletes foot. Afr. J. Microbiol. Res., 5: 2008-2010.
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  125. Somchit, M.N., H. Hassan, Z. Ahmad, L.C. Chong, Z. Mohamed and Z.A. Zakaria, 2011. In vitro anti-fungal and anti-bacterial activity of Drymoglossum piloselloides L. Presl. against several fungi responsible for Athlete's foot and common pathogenic bacteria. Afr. J. Microbiol. Res., 5: 3537-3541.
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  126. Rofiee, M.S., Z.A. Zakaria, M.N. Somchit, A. Zuraini and A.K. Arifah et al., 2011. Involvement of CYP450 system in hepatoprotective activity of Malaysian Agricultural Research and Development Institute (MARDI)-produced virgin coconut oils. Afr. J. Pharm. Pharmacol., 5: 2526-2536.
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  127. Pihie, A.H.L., F. Othman and Z.A. Zakaria, 2011. Anticarcinogenic activity of Labisia pumila against 7, 12-dimethylbenz (a) anthracene (DMBA)/croton oil-induced mouse skin carcinogenesis. Afr. J. Pharm. Pharmacol., 5: 823-832.
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  128. Perimal, E.K., M.N. Akhtar, A.S. Mohamad, M.H. Khalid and O.H. Ming et al., 2011. Zerumbone-induced antinociception: Involvement of the L-arginine-nitric oxide-cGMP-PKC-K+ATP channel pathways. Basic Clin. Pharmacol. Toxicol., 108: 155-162.
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  129. Ong, H.M., A.S. Mohamad, N.A. Makhtar, M.H. Khalid and S. Khalid et al., 2011. Antinociceptive activity of methanolic extract of Acmella uliginosa (Sw.) Cass. J. Ethnopharmacol., 133: 227-233.
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  130. Khan, M.S.A., S.A. Hussain, A.M.M. Jais, Z.A. Zakaria and M. Khan, 2011. Anti-ulcer activity of Ficus religiosa stem bark ethanolic extract in rats. J. Med. Plants Res., 5: 354-359.
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  131. Khan, M.S.A., A.M.M. Jais, M. Khan, Z.A. Zakaria and M. Ranjbar, 2011. Gastroprotective effect of Tabernaemontana divaricata (L). R.Br. flower methanolic extract in rats. Pharmacologyonline, 2: 24-35.
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  132. Chiong, H.S., M.N. Hakim, M.R. Sulaiman, Z.A. Zakaria, A. Zuraini, S.G.M. Ong and K.H. Yuen, 2011. Development and characterisation study of liposomes-encapsulated piroxicam. Int. J. Drug Deliv., 3: 64-73.
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  133. Ang, K.P., H.K. Tan, M. Selvaraja, A.A. Kadir and M.N. Somchit et al., 2011. Cryptotanshinone attenuates in vitro oxLDL-induced pre-lesional atherosclerotic events. Planta Med., 77: 1782-1787.
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  134. Akim, A.M., L.C. Ling, A. Rahmat and Z.A. Zakaria, 2011. Antioxidant and anti-proliferative activities of roselle juice on Caov-3, MCF-7, MDA-MB-231 and HeLa cancer cell lines. Afr. J. Pharm. Pharmacol., 5: 957-965.
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  135. Achenef, M.B., A.K. Arifah, Y.M. Goh, A.Q. Sazili and O. Fauziah et al., 2011. Conjugated linoleic acids in cattle slaughtered for human consumption. J. Anim. Vet. Adv., 10: 38-42.
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  136. Zakaria, Z.A., Z. Ahmad, M.N. Somchit, A.K. Arifah and M.R. Sulaiman et al., 2010. Antihypercholesterolemia property and fatty acid composition of MARDI-produced virgin coconut oils. Afr. J. Pharm. Pharmacol., 4: 636-644.
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  137. Zakaria, Z.A., H. Patahuddin, A.S. Mohamad, D.A. Israf and M.R. Sulaiman, 2010. In vivo anti-nociceptive and anti-inflammatory activities of the aqueous extract of the leaves of Piper sarmentosum. J. Ethnopharmacol., 128: 42-48.
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  138. Zakaria, Z.A., A.S. Sufian, K. Ramasamy, N. Ahmat and M.R. Sulaiman et al., 2010. In vitro antimicrobial activity of Muntingia calabura extracts and fractions. Afr. J. Microbiol. Res., 4: 304-308.
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  139. Zakaria, Z.A., A.S. Mohamed, C.T. Chear, W.Y. Yew, D.A. Israf and M.R. Sulaiman, 2010. Antiinflammatory and antinociceptive activities of Zingiber zerumbet methanol extract in experimental model systems. Med. Principles Practice, 19: 287-294.
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  140. Zakaria, Z.A., A.S. Mohamad, M.S. Ahmad, A.F. Mokhtar and D.A. Israf, N.H. Lajis and M.R. Sulaiman, 2010. Preliminary analysis of the anti-inflammatory activity of essential oils of Zingiber zerumbet. Biol. Res. Nurs., 13: 425-432.
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  141. Zakaria, Z.A., A.M. Desa, K. Ramasamy, N. Ahmat, A.S. Mohamad, D.A. Israf and M.R. Sulaiman, 2010. Lack of antimicrobial activities of Dicranopteris linearis extracts and fractions. Afr. J. Microbiol. Res., 4: 71-75.
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  142. Yassir, M.A., A.K. Arifah, H. Yaakub, A. Zuraini and Z.A. Zakaria, 2010. Comparison of Conjugated linoleic acid and other fatty acid content of milk fat of mafriwal and jersey cows. J. Anim. Vet. Adv., 9: 1318-1323.
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  143. Tham, C.L., C.Y. Liew, K.W. Lam, A.S. Mohamad and M.K. Kim et al., 2010. A synthetic curcuminoid derivative inhibits nitric oxide and proinflammatory cytokine synthesis. Eur. J. Pharmacol., 628: 247-254.
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  144. Teh, L.K., M.K. Zahri, Z.A. Zakaria, R. Ismail and M.Z. Salleh, 2010. Mutational analysis of CYP2C8 in hypertensive patients using denaturing high performance liquid chromatography. J. Clin. Pharm. Therapeut., 35: 723-728.
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  145. Sulaiman, M.R., Z.A. Zakaria, A.S. Mohamad, M. Ismail, M.T. Hidayat, D.A. Israf and M. Adilius, 2010. Antinociceptive and anti-inflammatory effects of the ethanol extract of Alpinia conchigera rhizomes in various animal models. Pharma. Biol., 48: 861-868.
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  146. Sulaiman, M.R., Z.A. Zakaria, A. Abdul-Rahman, A.S. Mohamad and M.N. Desa et al., 2010. Antinociceptive and antiedematogenic activities of andrographolide isolated from Andrographis paniculata in animal models. Biol. Res. Nurs., 11: 293-301.
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  147. Sulaiman, M.R., T.A.S.T. Mohamad, W.M.S. Mossadeq, S. Moin and M. Yusof et al., 2010. Antinociceptive activity of the essential oil of zingiber zerumbet. Planta Medica, 76: 107-112.
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  148. Sulaiman, M.R., E.K. Perimal, M.N. Akhtar, A.S. Mohamad and M.H. Khalid et al., 2010. Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice. Fitoterapia, 81: 855-858.
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  149. Somchit, M.N., R.A. Rashid, A. Abdullah, A. Zuraini and Z.A. Zakaria et al., 2010. In vitro antimicrobial activity of leaves of Acalypha indica Linn (Euphorbiaceae). Afr. J. Microbiol. Res., 4: 2133-2136.
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  150. Ponto, T., A.Z. Musa, N.I. Ismail, A.B. Abdul Majeed, N.H. Marmaya and Z.A. Zakaria, 2010. A prospective study on the pattern of medication use for schizophrenia in the outpatient pharmacy department, Hospital Tengku Ampuan Rahimah, Selangor, Malaysia Methods Findings Clin. Exp. Pharmacol., 32: 427-432.
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  151. Mohamad, A.S., M.N. Akhtar, Z.A. Zakaria, E.K. Perimal and S. Khalid et al., 2010. Antinociceptive activity of a synthetic chalcone, flavokawin B on chemical and thermal models of nociception in mice. Eur. J. Pharmacol., 647: 103-109.
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  152. Merawin, L.T., A.K. Arifah, R.A. Sani, M.N. Somchit, Z. Ahmad, S. Ganabadi and Z.A. Zakaria, 2010. Screening of microfilaricidal effects of plant extracts against Dirofilaria immitis. Res. Vet. Sci., 88: 142-147.
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  153. Liew, C.Y., C.L. Tham, K.W. Lam, A.S. Mohamad and M.K. Kim et al., 2010. A synthetic hydroxypropenone inhibits nitric oxide, prostaglandin E2 and proinflammatory cytokine synthesis. Immunopharmacol. Immunotoxicol., 32: 495-506.
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  155. Israf, D.A., C.L. Tham, A. Syahida, N.H. Lajis, M.R. Sulaiman, A.S. Mohamad and Z.A. Zakaria, 2010. Atrovirinone inhibits proinflammatory mediator synthesis through disruption of NF-κB nuclear translocation and MAPK phosphorylation in the murine monocytic macrophage RAW 264.7. Phytomedicine, 17: 732-739.
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  156. Harasstani, O.A., S. Moin, C.L. Tham, C.Y. Liew and N. Ismail et al., 2010. Flavonoid combinations cause synergistic inhibition of proinflammatory mediator secretion from lipopolysaccharide-induced RAW 264.7 cells. Inflamm. Res., 59: 711-721.
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  157. Zuraini, A., A.H. Hasiah, H.M. Khairi, M.N. Somchit, S. Faizah and Z.A. Zakaria, 2009. Selective In vitro cytotoxic effects of piroxicam and mefenamic acid on several cancer cells lines. Res. J. Pharmacol., 3: 15-18.
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  158. Zakaria, Z.A., N.I.A. Rahman, Y.W. Loo, A.H.A. Ayub and M.R. Sulaiman et al., 2009. Antinociceptive and anti-inflammatory activities of the chloroform extract of Bauhinia purpurea L. (Leguminosae) leaves in animal models. Int. J. Trop. Med., 1: 140-145.
  159. Zakaria, Z.A., M.R. Sulaiman, N.A. Morsid, A. Aris, H. Zainal, N.H.M. Pojan and G.H. Kumar, 2009. Antinociceptive, anti-inflammatory and antipyretic effects of Solanum nigrum aqueous extract in animal models. Meth. Find. Exp. Clin. Pharmacol., 31: 81-88.
  160. Zakaria, Z.A., G.H. Kumar, R.R.M. Nor, M.R. Sulaiman and C.A. Fatimah et al., 2009. Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Corchorus capsularis leaves in experimental animal models. Pharm. Biol., 47: 104-110.
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  161. Sulaiman, M.R., Z.A. Zakaria, M. Adilius, A.S. Mohamad, M. Ismail and D.A. Israf, 2009. Antinociceptive and anti-inflammatory effects of the ethanol extract of Alpinia conchigera Griff. leaves in various animal models. Meth. Find. Exp. Clin. Pharmacol., 31: 241-247.
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  162. Sulaiman, M.R., Z.A. Zakaria, H.S. Chiong, S.K. Lai, D.A. Israf and T.A. Shah, 2009. Antinociceptive and anti-inflammatory effects of Stachytarpheta jamaicensis (L.) Vahl (Verbenaceae) in experimental animal models. Med. Principles Pract., 18: 272-279.
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  163. Sulaiman, M.R., E.K. Perimal, Z.A. Zakaria, F. Mokhtar, M.N. Akhtar, N.H. Lajis and D.A. Israf, 2009. Preliminary analysis of the antinociceptive activity of zerumbone. Fitoterapia, 80: 230-232.
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  164. Somchit, N., C.S. Ngee, A. Yaakob, Z. Ahmad and Z.A. Zakaria, 2009. Effects of cytochrome P450 inhibitors on itraconazole and fluconazole induced cytotoxicity in hepatocytes. J. Toxicol., Vol. 2009. 10.1155/2009/912320.
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  165. Shaik Mossadeq, W.M., M.R. Sulaiman, T.A. Tengku Mohamad, H.S. Chiong and Z.A. Zakaria et al., 2009. Anti-inflammatory and antinociceptive effects of Mitragyna speciosa Korth methanolic extract. Med. Princ. Pract., 18: 378-384.
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  166. Adam, Y., M.N. Somchit, M.R. Sulaiman, A.A. Nasaruddin, A. Zuraini, A.A. Bustamam and Z.A. Zakaria, 2009. Diuretic properties of Orthosiphon stamineus Benth. J. Ethnopharmacol., 124: 154-158.
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  167. Achenef, M.B., A.K. Arifah, Y.M. Goh, A.Q. Sazili and O. Fauziah et al., 2009. Conjugated linoleic acid in rumen liquor: Their relation with other carbon 18 fatty acids and rumen pH. J. Biol. Sci., 9: 567-572.
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  168. Zakaria, Z.A., Z.D.F. Abdul Ghani, G.H. Kumar, R.N.S.R.M. Nor and M.R. Sulaiman et al., 2008. Antinociceptive, Anti-Inflammatory and Anti-Pyretic Properties of Aqueous Leaf Extract of Dicranopteris linearis and Corchorus capsularis in Experimental Animal Models. In: Plant, Man and Health: Past, Present and Future, Shyun, C.Y. and N.M. Mustafa (Eds.)., Forest Research Institute of Malaysia, Kepong, Selangor, Malaysia, pp: 41-45.
  169. Zakaria, Z.A., Z.D. Ghani, R.N. Nor, H.K. Gopalan and M.R. Sulaiman et al., 2008. Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Dicranopteris linearis leaves in experimental animal models. J. Nat. Med., 62: 179-187.
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  170. Zakaria, Z.A., M.N. Somchit, M.R. Sulaiman, A.M. Mat Jais and C.A. Fatimah, 2008. Effects of various opioid and non-pioid antagonists, pH and enzymes on Muntingia calabura antinociception in mice. Res. J. Pharmacol., 2: 31-37.
  171. Zakaria, Z.A., G.H. Kumar, A.J. Mat, M.R. Sulaiman and M.N. Somchit, 2008. Antinociceptive, antiinflammatory and antipyretic properties of Channa striatus fillet aqueous and lipid-based extracts in rats. Meth. Find. Exp. Clin. Pharmacol., 30: 355-362.
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  172. Zakaria, Z.A., A.M. Mohamed, N.S.M. Jamil, M.S. Rofiee and C.A. Fatimah et al., 2008. In vitro anticancer activity of various extracts of the Malaysian, available but neglected, plants (Muntingia calabura and Dicranopteris linearis) against Mcf-7 And Ht-29 cancer cell lines. E-Pharmanexus, 1: 10-17.
  173. Sulaiman, M.R., Z.A. Zakaria, S. Moin, M.N. Somchit, D.A. Israf and Y.S. Chai, 2008. Anti-inflammatory and antinociceptive effects of Lonicera japonica Thunb. Res. J. Pharmacol., 2: 38-42.
  174. Sulaiman, M.R., Z.A. Zakaria, I.A. Daud, F.N. Ng, Y.C. Ng and M.T. Hidayat, 2008. Antinociceptive and anti-inflammatory activities of the aqueous extract of Kaempferia galanga leaves in animal models. J. Nat. Med., 62: 221-227.
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  175. Sulaiman, M.R., Z.A. Zakaria, A. Kamaruddin, F.M. Teoh, D.A. Israf and S. Moin, 2008. Antinociceptive and antiinflammatory activities of the aqueous extract of Trigonopleura malayana resin in experimental animal models. Meth. Find. Exp. Clin. Pharmacol., 30: 691-696.
    Direct Link  |  
  176. Sulaiman, M.R., R. Lihan and Z.A. Zakaria, 2008. Antinociceptive and anti-inflammatory Activities of Tinospora crispa in various animal models. Int. J. Trop. Med., 3: 66-69.
    Direct Link  |  
  177. Sulaiman, M.R., M.K. Hussin, Z.A. Zakaria, M.H. Khalid, C.Y. See, M.N. Somchit and D.A. Israf, 2008. Anti-inflammatory and antinociceptive activities of Ficus deltoidea aqueous axtract in mice and rats. Fitoterapia, 79: 557-561.
  178. Moin, S., D.A. Israf, M.N. Somchit, A.S. Bujarimin, Z.A. Zakaria and M.R. Sulaiman, 2008. Evaluation of Moringa oleifera aqueous extract for antinociceptive and anti-inflammatory activities in animal models. Pharm. Biol., 46: 838-845.
  179. Jais, A.M.M., Z.A. Zakaria, A. Luo and Y.X. Song, 2008. In vitro antifungal activity of Haruan (Channa striatus) crude extracts. Int. J. Trop. Med., 3: 43-48.
  180. Alias, A., M.R. Sulaiman, S. Moin and Z.A. Zakaria, 2008. Antinociceptive and anti-inflammatory effects of Sida rhombifolia L. in various animal models. Res. J. Pharmacol., 2: 13-16.
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  181. Zakaria, Z.A., S. Mustapha, M.R. Sulaiman, A.M.M. Jais, M.N. Somchit and F.C. Abdullah, 2007. The antinociceptive action of aqueous extract from Muntingia calabura leaves: The role of opioid receptors. Med. Princ. Prac., 16: 130-136.
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  182. Zakaria, Z.A., R.N.S.R.M. Nor, G.H. Kumar, Z.D.F.A. Ghani and C.A. Fatimah et al, 2007. Antinociceptive, Anti-inflammatory and anti-pyretic properties of Melastoma malabathricum leaves aqueous extract in experimental animals. Can. J. Physiol. Pharmacol., 84: 1291-1299.
  183. Zakaria, Z.A., N.A.M.N. Hazalin, S.N.H.M. Zaid, M.A. Ghani, M.H. Hassan, H.K. Gopalan and M.R. Sulaiman, 2007. Antinociceptive, anti-inflammatory and antipyretic effects of Muntingia calabura aqueous extract in animal models. J. Nat. Med., 61: 443-448.
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  184. Zakaria, Z.A., M.R. Sulaiman, G. Hanan-Kumar, Z.D.F. Abdul-Ghani and R.N.S. Raden-Mohd-Nor et al., 2007. Antinociceptive and anti-inflammatory properties of Corchorus capsularis leaves chloroform extract in experimental animal models. Yakugaku Zasshi, 127: 359-365.
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  185. Zakaria, Z.A., M.H. Hassan, M.N.H. Nurul Aqmar, M. Abd Ghani and S.N.H.M. Zaid et al., 2007. Effects of various nonopioid receptor antagonists on the antinociceptive activity of Muntingia calabura extracts in mice. Methods Find. Exp. Clin. Pharmacol., 29: 515-520.
  186. Zakaria, Z.A., L.Y. Wen, N.I.A. Rahman, A.H.A. Ayub, M.R. Sulaiman and H.K. Gopalan, 2007. Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals. Med. Principles Pract., 16: 443-449.
    CrossRef  |  Direct Link  |  
  187. Zakaria, Z.A., H.G. Kumar, N.H. Siti, M. Zaid and M.A. Ghani et al., 2007. Analgesic and antipyretic actions of Muntingia calabura leaves chloroform extract in animal models. Oriental Pharm. Exp. Med., 7: 34-40.
    Direct Link  |  
  188. Zakaria, Z.A., H. Zaiton, E.F.P. Henie, A.M. Mat Jais and E.N.H.E. Zainuddin, 2007. In vitro antibacterial activity of Averrhoa belimbi leaves and fruits extracts. Int. J. Trop. Med., 2: 96-100.
  189. Zakaria, Z.A., A.M. Mat Jais, Y.M. Goh, M.R. Sulaiman and M.N. Somchit, 2007. Amino acid and fatty acid composition of an aqueous extract of Channa striatus (Haruan) that exhibits antinociceptive activity. Clin. Exp. Pharmacol. Physiol., 34: 198-204.
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  190. Zakaria, Z.A., A.M. Mat Jais, M. Mastura, S.H. Mat Jusoh and A.M. Mohamed et al., 2007. In vitro antistaphylococcal activity of the extracts of several neglected plants in Malaysia. Int. J. Pharmacol., 3: 428-431.
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  191. Zakaria, Z.A., 2007. Free radical scavenging activity of some plants available in Malaysia. Iran. J. Pharmacol. Ther., 6: 87-91.
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  192. Sulaiman, M.R., S. Sainan, Z.A. Zakaria, M.N. Somchit, D.A. Israf, S. Moin and T.A.S.T. Mohamad, 2007. Antinociceptive profile of the ethanolic extract of Andrographis paniculata in mice. Oriental Pharm. Exp. Med., 7: 390-394.
  193. Somchit, M.N., S.S. Rahmah, A. Zuraini, A.A. Bustamam, Z.A. Zakaria and L. Shamsuddin, 2007. Gastroprotective activity of Spirulina platensis in acetic acid and ethanol induced ulcers in rats. J. Nat. Remedies, 7: 37-42.
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  194. Zuraini, A., M.N. Somchit, M.H. Solihah, Y.M. Goh and A.K. Arifah et al., 2006. Fatty acid and amino acid composition of three local Malaysian Channa spp. fish. Food Chem., 97: 674-678.
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  195. Zakaria, Z.A., Z.D.F. Abdul-Ghani, R.N.S. Raden-Mohd. N.G. Hanan-Kumar, M.R. Sulaiman and C.A. Fatimah, 2006. Antinociceptive and anti-inflammatory activities of Dicranopteris linearis leaves chloroform extract in experimental animals. Yakugaku Zasshi, 126: 1197-1203.
    Direct Link  |  
  196. Zakaria, Z.A., R.N.S.R.M. Nor, M.R. Sulaiman, Z.D.F.A. Ghani, G.H. Kumar and C.A. Fatimah, 2006. Antinociceptive and anti-inflammatory properties of Melastoma malabathricum leaves chloroform extract in experimental animals. J. Pharmacol. Toxicol., 1: 337-345.
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  197. Zakaria, Z.A., R. Valsala, M.R. Sulaiman, M.N. Somchit and C.A. Fatimah, 2006. The Heat-Stable Antinociceptive Activity of Aqueous Extract of Muntingia calabura Leaves Mediated Via Opioid Receptor. In: Malaysian Medicinal Plants: Chemistry and Biological Activity, Ahmad, F., Z. Assim, L. Din and I.M. Said (Eds.). Universiti Malaysia, Sarawak, Malaysia, pp: 93-98.
  198. Zakaria, Z.A., M.R. Sulaiman, A.M. Mat Jais, M.N. Somchit, V.J. Kogilla, R. Ganesh and C.A. Fatimah, 2006. The involvements of L-arginine/nitric oxide/cyclic-guanosine monophosphate pathway in Muntingia calabura aqueous extract antinociception in mice. Fundam. Clin. Pharmacol., 20: 365-372.
  199. Zakaria, Z.A., M.R. Sulaiman, A.K. Arifah, A.M.M. Jais and M.N. Somchit et al., 2006. The anti-inflammatory and antipyretic activities of Corchorus olitorius in rats. J. Pharmacol. Toxicol., 1: 139-146.
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  200. Zakaria, Z.A., M.N. Somchit, M.R. Sulaiman, A.M. Mat Jais and C.A. Fatimah, 2006. Effects of l-Arginine, l-NAME, methylene blue and their combinations on Corchorus olitorius. Aqueous extract antinociception in mice. Pharm. Biol., 44: 430-439.
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  201. Zakaria, Z.A., M.N. Somchit, H. Zaiton, A.M. Mat Jais and M.R. Sulaiman et al., 2006. The in vitro antibacterial activity of Corchorus olitorius extracts. Int. J. Pharmacol., 2: 213-215.
    CrossRef  |  Direct Link  |  
  202. Zakaria, Z.A., M. Neelendran, S. Pubalan, M.R. Sulaiman and C.A. Fatimah, 2006. Effects of opioid and non-opioid antagonists, pH and enzymes on Corchorus olitorius antinociception in mice. Oriental Pharm. Exp. Med., 6: 186-195.
    Direct Link  |  
  203. Zakaria, Z.A., I. Reezal, A.M.M. Jais, M.N. Somchit amd M.R. Sulaiman et al., 2006. The anti-inflammatory, anti-pyretic and wound healing activities of Cocos nucifera (MATAG Types) fresh juice and kernel extract in experimental animals. J. Pharmacol. Toxicol., 1: 516-526.
    CrossRef  |  Direct Link  |  
  204. Zakaria, Z.A., H.M. Khairi, M.N. Somchit, M.R. Sulaiman and A.M.M. Jais et al., 2006. The in vitro antibacterial activity and brine shrimp toxicity of Manihot esculenta var. Sri Pontian (Euphorbiacea) extract. Int. J. Phamacol., 2: 216-220.
    CrossRef  |  Direct Link  |  
  205. Zakaria, Z.A., H.K. Gopalan, H. Zainal, N.H.M. Pojan, N.A. Morsid, A. Aris and M.R. Sulaiman, 2006. Antinociceptive, anti-inflammatory and antipyretic effects of Solanum nigrum chloroform extract in animal models. Yakugaku Zasshi, 126: 1171-1178.
    CrossRef  |  Direct Link  |  
  206. Zakaria, Z.A., H. Zaiton, E.F.P. Henie, A.M.M. Jais and D. Kasthuri et al., 2006. The in vitro antibacterial activity of Corchorus olitorius and Muntingia calabura extracts. J. Pharmacol. Toxicol., 1: 108-114.
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  207. Zakaria, Z.A., C.A. Fatimah, M. Safarul, R. Valsala, M.R. Sulaiman and A.M. Mat Jais, 2006. Influence of Temperature on the Opioid-Mediated Antinociceptive Activity of Corchorus olitorius L. in Mice. In: Malaysian Medicinal Plants: Chemistry and Biological Activity, Ahmad, F., Z. Assim, L. Din and I.M. Said (Eds.). Universiti Malaysia, Sarawak, Malaysia, pp: 83-88.
  208. Zakaria, Z.A., C.A. Fatimah, A.M. Mat-Jais, H. Zaiton and E.F.P. Henie et al., 2006. The in vitro antibacterial activity of Muntingia calabura extracts. Int. J. Pharmacol., 2: 290-293.
  209. Zakaria, Z.A., A.M. Mat Jais, M.R. Sulaiman, S.S.P. Mohamed Isa and S. Riffin, 2006. The in vitro antibacterial activity of methanol and ethanol extracts of Carica papaya flowers and Mangifera indica leaves. J. Pharmacol. Toxicol., 1: 278-283.
    CrossRef  |  Direct Link  |  
  210. Zakaria, Z.A., A.M. Mat Jais, M.N. Somchit, M.R. Sulaiman and C.A. Fatimah, 2006. Report on some of the physical properties of bioactive compounds responsible for the Channa striatus fillet extract antinociceptive activity. J. Boil. Sci., 6: 680-686.
    CrossRef  |  Direct Link  |  
  211. Zakaria, Z.A., A.M. Mat Jais, E.F.P. Henie, H. Zaiton, M.N. Somchit, M.R. Sulaiman and F.O. Faizal, 2006. The in vitro antibacterial activity of Tinosprora crispa extracts. J. Boil. Sci., 6: 398-401.
    CrossRef  |  Direct Link  |  
  212. Zakaria, Z.A., A.K. Arifah, A.M.M. Jais, M.R. Sulaiman and M.N. Somchit, 2006. G09 Amino acid and fatty acid compositions of the aqueous extract of channa striatus. J. Vet. Pharmacol. Therapeut., 29: 208-209.
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  213. Solihah, M.H., M.N. Somchit, A.D.A. Zuraini, A.K. Arifah, M.S. Zakaria, M.R. Sulaiman and A.M.M. Jais, 2006. Analgesic activity of three Channa spp. fish extracts. Oriental Pharm. Exp. Med., 6: 349-354.
    Direct Link  |  
  214. Zakaria, Z.A., M.R. Sulaiman, M.N. Somchit, A.M. Mat Jais and D.I. Ali, 2005. The effects of L-arginine, D-arginine, L-name and methylene blue on Channa striatus-induced peripheral antinociception in mice. J. Pharm. Pharm. Sci., 8: 199-206.
    Direct Link  |  
  215. Zakaria, Z.A., M.R. Sulaiman, M.N. Somchit and A.M. Mat Jais, 2005. Evaluation of the onset and offset time of aqueous supernatant of haruan (Channa striatus) fillet antinociception administered subcutaneously in mice. Pak. J. Biol. Sci., 8: 466-469.
    CrossRef  |  Direct Link  |  
  216. Zakaria, Z.A., M.R. Sulaiman, M.N. Somchit and A.M. Mat Jais, 2005. Effects of various antagonists on Haruan (Channa striatus) fillet extract antinociception in mice. Can. J. Physiol. Pharmacol., 83: 635-642.
    Direct Link  |  
  217. Zakaria, Z.A., M. Safarul, R. Valsala, M.R. Sulaiman, C.A. Fatimah and A.M. Mat-Jais, 2005. Influence of temperature on the opioid-mediated antinociceptive activity of Corchorus olitorius L. in mice. Naunyn Schmiedeberg's Arch. Pharmacol., 372: 55-62.
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  218. Zakaria, Z.A., M.R. Sulaiman, M.N. Somchit, A.M. Mat Jais and D.A. Israf, 2004. Non-opioid antinociceptive activity of fresh Haruan (Channa striatus) fillet extract. J. Manage. Sci., 2: 6-11.
  219. Zakaria, Z.A., M.R. Sulaiman, M.N. Somchit and A.M. Mat Jais, 2004. Effects of α-amylase, protease and lipase on Haruan (Channa striatus) mucus extracts antinociceptive activity. J. Manage. Sci., 2: 9-15.
  220. Zakaria, Z.A., M.R. Sulaiman, A.M.M. Jais and M.N. Somchit, 2004. Effects of -amylase, protease and lipase on haruan (Channa striatus) mucus extract antinociceptive activity in mice. Pak. J. Biol. Sci., 7: 2202-2207.
    CrossRef  |  Direct Link  |  
  221. Zakaria, Z.A., M.N. Somchit, M.R. Sulaiman and A.M. Mat Jais, 2004. Preliminary investigation on the antinociceptive properties of haruan (Channa striatus) fillet extracted with various solvent systems. Pak. J. Biol. Sci., 7: 1706-1710.
    CrossRef  |  Direct Link  |  
  222. Zakaria, Z.A., M.R. Sulaiman, M.N. Somchit, E.C. Justin, A.M. Mat Jais and D.A. Israf, 2003. The role of peripheral L-arginine/nitric oxide/cyclic-GMP pathway in Haruan (Channa striatus)-induced antinociception. J. Manage. Sci., 1: 15-25.