Dr. Zulkhairi Bin Hj Amom
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Dr. Zulkhairi Bin Hj Amom

Deputy Dean
Faculty of Health Sciences, Universiti Teknologi Mara, Malaysia


Highest Degree
Ph.D. in Biomedicine from Universiti Kebangsaan Malaysia, Malaysia

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Area of Interest:

Pharmacology and Toxicology
100%
Alternative Medicine
62%
Clinical Nutritionist
90%
Medicinal Plants
75%
Biotechnology
55%

Research Publications in Numbers

Books
0
Chapters
2
Articles
71
Abstracts
0

Selected Publications

  1. Dasiman, R., M.A. Malek, E.A. Bahari, F.N. Zakaria and N.K. Hashim et al., 2020. Effect of Croton caudatus geiseler aqueous root extract on reproductive and biochemical parameters in male Wistar rats. Indones. Biomed. J., 12: 251-260.
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  2. Ahmad, V.N., Z. Amom, I.M. Amin, N.B. Ruslan, N.M. Zain and M.A.A. Rahim, 2020. Pathogenesis of atherosclerosis and alpha lipoic acid as a potential therapeutic agent against atherosclerosis-A review. J. Health Transl. Med., 23: 42-48.
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  3. Jagadeesan, S., S.M. Chiroma, M.T.H. Baharuldin, C.N.M. Taib, Z. Amom, M.I. Adenan and M.A.M. Moklas, 2019. Centella asiatica prevents chronic unpredictable mild stress-induced behavioral changes in rats. Biomed. Res. Ther., 6: 3233-3243.
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  4. Chiroma, S.M., M.T.H. Baharuldin, C.N.M. Taib, Z. Amom, S. Jagadeesan, M.I. Adenan and M.A.M. Moklas, 2019. Protective effect of Centella asiatica against D-galactose and aluminium chloride induced rats: Behavioral and ultrastructural approaches. Biomed. Pharmacother., 109: 853-864.
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  5. Chiroma, S.M., M.T.H. Baharuldin, C.N.M. Taib, Z. Amom and S. Jagadeesan et al., 2019. Centella asiatica Protects d-Galactose/AlCl3 mediated alzheimer's disease-like rats via PP2A/GSK-3β signaling pathway in their hippocampus. Int. J. Mol. Sci., Vol. 20. 10.3390/ijms20081871.
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  6. Chiroma, S.M., M. Baharuldin, T.C. Mat., Z. Amom and S. Jagadeesan et al., 2019. Protective effects of centella asiatica on cognitive deficits induced by D-gal/AlCl3 via inhibition of oxidative stress and attenuation of acetylcholinesterase level. Toxics, Vol. 7. 10.3390/toxics7020019.
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  7. Chiroma, S.M., T.H. Baharuldin, C. Norma, M. Taib, Z. Amom and M.A. Mohd, 2018. Inflammation in Alzheimer’s disease: A friend or foe? Biomed. Res. Ther., 5: 2552-2564.
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  8. Chiroma, S.M., M.M.A. Mohd, C.N.M. Taib, M.T.H. Baharuldin and Z. Amon, 2018. D-galactose and aluminium chloride induced rat model with cognitive impairments. Biomed. Pharmacother., 103: 1602-1608.
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  9. Chiroma, S.M., M.A.M. Moklas, C.M. Norma, M.H. Taufik, Z. Amon, S. Jagadeesan and B. Ibrahim, 2017. Neuro-therapeutic benefits of centella asiatica on some neurodegenerative diseases: A review. Res. J. Pharm. Biol. Chem., 8: 549-556.
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  10. Suliman, N.A., M.A.M. Moklas, C.N. Mat Taib, M.I. Adenan, M.T. Hidayat Baharuldin, R. Basir and Z. Amom, 2016. Morphine antidependence of Erythroxylum cuneatum (Miq.) Kurz in neurotransmission processes in vitro. Evidence-Based Complement. Altern. Med., Vol. 2016. 10.1155/2016/3517209.
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  11. Ismail, M.A.H., E.A. Bahari, F.S. Ibrahim, R. Dasiman and Z. Amom, 2016. Effects of gynura procumbens extract on liver function test of hypercholesterolemia induced rabbits. J. Teknol., 78: 49-54.
  12. Hussain, R.M., N.F. Abdullah and Z. Amom, 2016. Killing of Staphylococcus aureus by allylpyrocatechol is potentiated by induction of intracellular oxidative stress and inhibition of catalase activity. J. Integrat. Med., 14: 456-464.
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  13. Bahari, E.A., M.A.H. Ismail, R. Dasiman, N. Haron and Z. Amom, 2016. The effect of phyllanthus comphocarpus Hook. F. aqueous extract supplementation on androgenic hormonal level and histological testes morphometry. J. Teknol., 78: 55-60.
  14. Abdullah, N.F., R.M. Hussain and Z. Amom, 2016. Effect of APC on killing of Staphylococcus aureus by oxidative stress agents. J. Teknol., 78: 39-44.
  15. Zamree, M.S., S.K. Ihsan, K.A. Khairul, K.N. Mohd and M.A. Rasadah et al., 2015. Lipid lowering and anti-atherosclerotic properties of Tinospora crispa aqueous extract on high-cholesterol diet-induced hyperlipidemic rabbits. Afr. J. Biotechnol., 14: 2604-2610.
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  16. Haron, N., N. Abu Hasan, S.N. Camalxaman, E. Mohamed, A.S. Rambely and Z. Amom, 2015. Protective effect of Stevia rebaudiana leaf extract on hemolytic behaviour of human erythrocyte in hydrogen peroxide-induced oxidative stress. Esteem Acad. J.: Eng. Sci. Technol., 11: 1-13.
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  17. Zulkhairi, H.A., A. Azrina and M.E. Norhaizan, 2014. Therapeutic Utility of Malaysian Rice. In: Current Trends in Medicinal Botany, Iqbal, M. and A. Ahmad (Eds.)., I.K. Intnl Pub Hse Pvt. Ltd, India, pp: 213-238.
  18. Hassan, M.K.N., R.M. Ali, Z.H. Amom and M.S.M. Arshad, 2014. Kesan apigenin, berberin dan rutin terhadap metabolisme kolesterol pada sel kanser hep G2. [Effect of apigenin, berberine and rutin on cholesterol metabolism in Hep G2 cancer cell]. Sains Malaysiana, 43: 559-566.
  19. Bahari, E.A., N.E. Zaaba, N. Haron, R. Dasiman and Z. Amom, 2014. Antioxidant activity characterization, phytochemical screening and proximate analysis of cermela hutan (Phyllanthus gomphocarpus Hook. F) roots and leaves. Med. Sci. Monitor Basic Res., 20: 170-175.
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  20. Saleem, A.M., H.M. Taufik, A.M. Jais, S. Fakurazi and M.A. Moklas et al., 2013. Involvement of monoaminergic system in the antidepressant-like effect of aqueous extract of Channa striatus in mice. Eur. Rev. Med. Pharmacol. Sci., 17: 2019-2022.
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  21. Moklas, M.A.M., N.A. Suliman, C.N.M. Taib, M.T.H. Baharuldin and S. Fakurazi et al., 2013. Sedative, cognitive impartment and anxiolytic effects of acute Mitragyna speciosa in rodents. J. US-China Med. Sci., 10: 37-44.
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  22. Kamalruazman, D., S. Afiqah, B.E. Anuar, A.R.N. Syahida and S.N. Jannah et al., 2013. Hepatoxicity, nephrotoxicity and anti-infertility activities of aqueous extract of Croton caudatus Geiseler (leaves) in male rat model. Asia Pac. J. Mol. Biol. Biotechnol., Vol. 21. .
  23. Ikhtifar, M.R.M., B.E. Anuar, S. Afiqah, D. Kamalruazman, D. Razif, I.F. Shafeera and A. Zulkhairi, 2013. Antioxidant, total phenolic and total flavanoid content in various parts of Croton caudatus geiseler. Asia Pac. J. Mol. Biol. Biotechnol., Vol. 21. .
  24. Esa, N.M., K.K.A. Kadir, Z. Amom and A. Azlan, 2013. Antioxidant activity of white rice, brown rice and germinated brown rice (in vivo and in vitro) and the effects on lipid peroxidation and liver enzymes in hyperlipidaemic rabbits. Food Chem., 141: 1306-1312.
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  25. Camalxaman, S.N., Z.M. Zain, Z. Amom, M. Mustakim, E. Mohamed and A.S. Rambely, 2013. In vitro antimicrobial activity of Vigna radiate (L) Wilzeck extracts against gram negative enteric bacteria. World Applied Sci. J., 21: 1490-1494.
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  26. Anuar, B.E., S. Afiqah, D. Kamalruazman, A.R.N. Syahida and S.N. Jannah et al., 2013. Sperm analysis on rats treated with aqueous extract of Croton caudatus geiseler (roots). Asia Pac. J. Mol. Biol. Biotechnol., Vol. 21. .
  27. Shakirin, F.H., A. Azlan, A. Ismail, Z. Amom and L.C. Yuon, 2012. Protective effect of pulp oil extracted from Canarium odontophyllum Miq. fruit on blood lipids, lipid peroxidation and antioxidant status in healthy rabbits. Oxidat. Med. Cell. Longevity, Vol. 12. .
  28. Shakirin, F.H., A. Azlan, A. Ismail, Z. Amom and L.C. Yuon, 2012. Antiatherosclerotic effect of Canarium odontophyllum Miq. fruit parts in rabbits fed high cholesterol diet. Evidence-Based Complement. Alternat. Med., 10.1155/2012/838604.
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  29. Nurulhuda, M.H., A. Azlan, A. Ismail, Z. Amom and F.H. Shakirin, 2012. Cholesterol-lowering and Artherosclerosis Inhibitory Effect of Sibu Olive in Cholesterol Fed-rabbit Asian J. Biochem., 7: 80-89.
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  30. Nursakinah, I., H.A. Zulkhairi, M. Norhafizah, B. Hasnah and D. Razif, 2012. Nutritional content and in vitro antioxidant potential of Garcinia atroviridis (Asam gelugor) leaves and fruits. Malaysian J. Nutr., 18: 363-371.
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  31. Moklas, M.A.M., Z. Amom, M.T.H. Baharuldin, C.N.M. Taib and F.N. Zakaria et al., 2012. Chronic Delta-9-tetrahydrocannabinol induces monoamine release but not conditioned place preference. Open Behav. Sci. J., 6: 31-36.
  32. Kamarazaman, I.S., Z.H. Amom, R.M. Ali, A.M. Akim and K.F. Azman et al., 2012. Protective effects of Tinospora crispa extracts on H2O2-induced oxidative stress and TNF-α-induced inflammation on Human Umbilical Vein Endothelial Cells (HUVECs). J. Med. Plants Res., 6: 3013-3021.
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  33. Ihsan, S.K., H.A. Zulkhairi, M.A. Rasadah, M.A. Abdah and F.A. Khairunnur et al., 2012. Inhibitory properties of Tinospora crispa extract on TNF-α induced inflammation on human umbilical vein endothelial cells (HUVECs). Int. J. Trop. Med., 7: 24-29.
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  34. Azman, K.F., Z. Amom, A. Azlan, N.M. Esa, R.M. Ali, Z.M. Shah and K.K.A. Kadir, 2012. Antiobesity effect of Tamarindus indica L. pulp aqueous extract in high-fat diet-induced obese rats. J. Natural Med., 66: 333-342.
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  35. Amom, Z., M.K.N. Hasan, M.T.H. Baharuldin, K.K. Abdul Kadir and Z.M. Shah et al., 2012. Assessment of antioxidative properties of aqueous leaf extract of Anacardium occidentale L. on human umbilical vein endothelial cells. Res. J. Med. Plants, 6: 597-606.
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  36. Zakaria, Z.A., M.L. Zakaria, Z. Amom and M.N.M. Desa, 2011. Antimicrobial activity of the aqueous extract of selected Malaysian herbs. Afr. J. Microbiol. Res., 5: 5379-5383.
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  37. Saleem, A.M., M.T. Hidayat, A.M. Mat Jais, S. Fakurazi, M.A. Mohamad Moklas, M.R. Sulaiman and Z. Amom, 2011. Antidepressant-like effect of aqueous extract of Channa striatus fillet in mice models of depression. Eur. Rev. Med. Pharmacol. Sci., 15: 795-802.
    PubMed  |  
  38. Rusydi, M.R.M., C.W. Noraliza, A. Azrina and A. Zulkhairi, 2011. Nutritional changes in germinated legumes and rice varieties. Int. Food Res. J., 18: 703-713.
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  39. Mahalingam, D., A.K. Radhakrishnan, Z. Amom, N. Ibrahim and K. Nesaretnam, 2011. Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers. Eur. J. Clin. Nutr., 65: 63-69.
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  40. Ihsan, S.K., A. Zulkhairi, M.A. Abdah, J.A. Daryl and I. Noramalina et al., 2011. Antioxidant properties of aqueous and methanol extract from Tinospora crispa and its ability to attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells. Res. J. Bio. Sci., 6: 230-236.
  41. Fazil, M.N.F., Z. Amom, N.M. Esa, M.K.N. Hasan, K.K.A. Kadir, Z.M. Shah and S.M. Arshad, 2011. Toxicity screening and hypocholesterolemic effect evaluation of aqueous extract of Anacardium occidentale Linn. in hypercholesterolemic induced rabbits. Int. J. Phytomed., 3: 192-197.
  42. Fazali F., A. Zulkhairi, M.E. Nurhaizan, N.H. Kamal, M.S. Zamree and M.A. Shahidan, 2011. Phytochemical screening, In vitro and In vivo antioxidant activities of aqueous extract of Anacardium occidentale linn. and its effects on endogenous antioxidant enzymes in hypercholesterolemic induced rabbits. Res. J. Biol. Sci., 6: 69-74.
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  43. Esa, N.M., K.K. Abdul Kadir, Z. Amom and A. Azlan, 2011. Improving the lipid profile in hypercholesterolemia-induced rabbit by supplementation of germinated brown rice. J. Agric. Food Chem., 59: 7985-7991.
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  44. Amom, Z., K.F. Azman, N.A. Ismail, Z. Shah and M.S.M. Arshad, 2011. An aqueous extract of tinospora crispa possesses antioxidative properties and reduces atherosclerosis in hypercholesterolemic‐induced rabbits. J. Food Biochem., 35: 1083-1098.
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  45. Al-Naqeep, G., A.S. Al-Zubairi, M. Ismail, Z.H. Amom and N.M. Esa, 2011. Antiatherogenic potential of Nigella sativa seeds and oil in diet-induced hypercholesterolemia in rabbits. Evidence-Based Complemen. Altern. Med., .
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  46. Zulkhairi, H.A., A.F. Khairunnuur, M.R.N. Hafipah, A. Azrina and M.A. Rasadah et al., 2010. An aqueous extract of Citrus mitis possesses antioxidative properties and improves plasma lipid profiles in rat induced with high cholesterol diet. J. Med. Plants Res., 4: 49-57.
  47. Khairunnuur, F.A., A. Zulkhairi, I. Hairuszah, A. Azrina and I. Nursakinah et al., 2010. Hypolipidemic and weight reducing properties from Tamarindus indica L. pulp extract in diet-induced obese rats. Int. J. Pharmacol., 6: 216-223.
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  48. Hasan, N.S., Z.H. Amom, A.I. Nor, N. Mokhtarrudin, N.M. Esa and A. Azlan, 2010. Nutritional composition and in vitro evaluation of the antioxidant properties of various dates extracts (Phoenix dactylifera L.) from libya. Asian J. Clin. Nutr., 2: 208-214.
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  49. Hasan, N.S., Z.H. Amom, A.I. Nor, D.J. Arapoc and A. Azrina, 2010. The role of dates (Phoenix dactylifera) aqueous extract in improving the plasma lipid profiles of diet-induced hypercholesterolemic rabbits. Res. J. Biol. Sci., 5: 632-637.
  50. Hafizah, A.H., Z. Zaiton, A. Zulkhairi, A.M. Ilham, M.M.N.N. Anita and A.M. Zaleha, 2010. Piper sarmentosum as an antioxidant on oxidative stress in human umbilical vein endothelial cells induced by hydrogen peroxide. J. Zhejiang Univ. Sci. B, 11: 357-365.
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  51. Azlan, A., K.N. Prasad, H.E. Khoo, N. Abdul-Aziz, A. Mohamad, A. Ismail and Z. Amom, 2010. Comparison of fatty acids, vitamin E and physicochemical properties of Canarium odontophyllum Miq. (dabai), olive and palm oils. J. Food Composit. Anal., 23: 772-776.
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  52. Khairunnuur, F.A., A. Zulkhairi, A. Azrina, M.A.M. Moklas, S. Khairullizam, M.S. Zamree and M.A. Shahidan, 2009. Nutritional composition, in vitro antioxidant activity and Artemia salina L. lethality of pulp and seed of Tamarindus indica L. extracts. Malysian J. Nutr., 15: 65-75.
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  53. Kamal, N.H.M., A. Zulkhairi, A.H. Hafizah, F. Fazali and A.K.K. Kamilah et al., 2009. Anacardium occidentale aqueous extract attenuates hydrogen peroxide-induced oxidative injury and inhibits inflammatory mediators expression in TNF-α-induced human umbilical vein endothelial cells during initial stage of atherogenesis. Res. J. Biol. Sci., 4: 1230-1235.
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  54. Azrina, A., P.H. Lim, I. Amin and A. Zulkhairi, 2009. Vitamin E and fatty acid composition of blended palm oils. J. Food Agric. Environ., 7: 256-262.
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  55. Azlan, A., N.N.M. Nasir, Z. Amom and A. Ismail, 2009. Physical properties of skin, flesh and kernel of Canarium odontophyllum fruit. J. Food, Agric. Environ., 7: 55-57.
  56. Amom, Z., H. Bahari, Z.M. Shah, M. Arshad and M. Shahidan et al., 2009. Potential of Tinospora crispa as a hypocholesterolemic agent in rabbits. Malaysian J. Med. Health Sci., 5: 1-10.
  57. Amom, Z., H. Bahari, S. Isemaail, N.A. Ismail, Z.M. Shah and M.S. Arsyad, 2009. Nutritional composition, antioxidant ability and flavonoids content of Tinospora crispa stem. Adv. Nat. Applied Sci., 3: 88-94.
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  58. Zulkhairi, A., Z. Zaiton, M. Jamaluddin, F. Sharida and T.H.B. Mohd et al., 2008. Alpha lipoic acid posses dual antioxidant and lipid lowering properties in atherosclerotic-induced New Zealand White rabbit. Biomed. Pharmacother., 62: 716-722.
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  59. Zulkhairi, A., M.A. Abdah, N.H.M. Kamal, I. Nursakinah and M.A.M. Moklas et al., 2008. Biological properties of Tinospora crispa (Akar Patawali) and its antiproliferative activities on selected human cancer cell lines. Malaysian J. Nutr., 14: 173-187.
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  60. Moklas, M.A.A., A.R. Nurul Rauddzah, M.T. Hidayat, F. Sharida, N.F. Idayu, A. Zulkhairi and M. Shamima, 2008. A preliminary toxicity study of mitragynine, an alkaloid from Mitragynine speciosa Korth and its effect on locomotor activity in rats. Adv. Med. Dental Sci., 2: 56-60.
  61. Kamilah, A.B.K., A. Azlan, Z. Amom, N.M. Esa and M. Ismail, 2008. Nutritional composition of germinated brown rice porridge. Food, 2: 57-60.
  62. Amom, Z., Z. Zakaria, J. Mohamed, A. Azlan and H. Bahari et al., 2008. Lipid lowering effect of antioxidant alpha-lipoic acid in experimental atherosclerosis. J. Clin. Biochem. Nutr., 43: 88-94.
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  63. Kamilah, A.K.K., I. Maznah, A. Zulkhairi, M.E. Norhaizan and A. Azrina, 2007. Chemical composition and antioxidant activity of white and brown rice. Malaysian J. Med. Sci., 14: 139-139.
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  64. Hidayat, M., A.A.R. Taufik, M.J. Hidatul, I. Abd. Manan and M. Amin et al., 2007. Therapeutic role of theobroma cacao in depressive disorders model on mice. Malaysian J. Med. Sci., 14: 106-106.
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  65. Hasnah, B., A. Zulkhairi, O. Fauziah, I. Maznah, H.M. Taufik, M.S. Zamree and M.A. Shahidan, 2007. Anti-atherogenic and antioxidant potency of tinospora crispa in rabbits fed with high fat diet. Malaysian J. Med. Sci., 14: 101-101.
  66. Zulkhairi, A., B. Hasnah, Z. Zaiton, M. Jamaludin, A. Zanariyah, K.A.K. Khairul and H.M. Taufik, 2006. Atheromatous plaque formation in rabbit aorta fed with high cholesterol diet. Malaysian J. Nutr., 12: 213-220.
  67. Amom, Z.H., H.M. Noor, L. Ling, M.T. Hidayat and H. Bahari, 2006. Effects of Anacardium occidentale Linn. leaves extract in diabetic rats. Malaysian J. Med. Sci., 14: 153-153.
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  68. Nizar, A.B., A. Zulkhairi, M.A. Abdah and R. Asmah, 2004. Screening of the antioxidant activities of Tinospora crispa (Patawali) extract. Curr. Trends Perspect., 3: 323-332.
  69. Zulkhairi, A., Z. Zaiton, O. Khairul, A. Zanariyah and M. Jamaluddin, 2001. The effect of ∞-Lipoic acid in blood lipid levels and malondialdehyde in atherosclerotic-induced New Zealand white rabbit. Malaysian J. Med. Sci., 8: 46-52.
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