Eunus S. Ali
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Eunus S. Ali

Postdoc
Northwestern University


Highest Degree
Ph.D. in Biochemistry, Molecular Biology and Cell Biology from Flinders University, Adelaide, Australia

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Area of Interest:

Biochemistry and Molecular Biology
100%

Research Publications in Numbers

Books
0
Chapters
0
Articles
30
Abstracts
0

Selected Publications

  1. Soflaee, M.H., R. Kesavan, U. Sahu, A. Tasdogan and E. Villa, et al., 2022. Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway. Nat. Commun., Vol. 13. 10.1038/s41467-022-30362-z.
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  2. Ali, E.S., A. Lipońska, B.P. O’Hara, D.R. Amici and M.D. Torno, 2022. The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis. Mol. Cell, 82: 3284-3298.
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  3. Villa, E., U. Sahu, B.P. O’Hara, E.S. Ali and K.A. Helmin et al., 2021. mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis. Mol. Cell, 10.1016/j.molcel.2021.03.009.
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  4. Shireman, J.M., F. Atashi, G. Lee, E.S. Ali and M.R. Saathoff et al., 2021. De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma. Brain, 144: 1230-1246.
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  5. Ali, E.S., U. Sahu, E. Villa, B.P. O’Hara and P. Gao et al., 2020. ERK2 phosphorylates PFAS to mediate posttranslational control of de novo purine synthesis. Mol. Cell, 78: 1178-1191.e6.
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  6. Ali, E.S., G.Y. Rychkov and G.J. Barritt, 2020. Targeting Ca2+ signaling in the initiation, promotion and progression of hepatocellular carcinoma. Cancers, 10.3390/cancers12102755.
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  7. Villa, E., E. Ali, U. Sahu and I. Ben-Sahra, 2019. Cancer cells tune the signaling pathways to empower de novo synthesis of nucleotides. Cancers, 10.3390/cancers11050688.
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  8. Saathoff, M., J. Shireman, E. Ali, C. Park, I. Ben-Sahra and A. Ahmed, 2019. DRES-09. regulatory effects of the ciliary gtpase ARL13B on purine metabolism in GBM. Neuro-Oncol., Vol. 21. 10.1093/neuonc/noz175.297.
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  9. Ali, E.S., G.Y. Rychkov and G.J. Barritt, 2019. Deranged hepatocyte intracellular Ca2+ homeostasis and the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma. Cell Calcium, Vol. 82. 10.1016/j.ceca.2019.102057.
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  10. Ali, E.S. and N. Petrovsky, 2019. Calcium signaling as a therapeutic target for liver steatosis. Trends Endocrinol. Metab., 30: 270-281.
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  11. Ahmed, A.U., J. Shireman, F. Atashi, M. Saathoff and E. Ali et al., 2019. OS6.1 targeting purine metabolism to overcome therapeutic resistance in glioblastoma. Neuro-Oncol., Vol. 21. 10.1093/neuonc/noz126.039.
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  12. Tam, K.C., E. Ali, J. Hua, T. Chataway and G.J. Barritt, 2018. Evidence for the interaction of peroxiredoxin-4 with the store-operated calcium channel activator STIM1 in liver cells. Cell Calcium, 74: 14-28.
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  13. Paz, M.F.C.J., M.V.O.B.D. Alencar, A.L.G. Junior, K.D.C. Machado and M.T. Islam et al., 2018. Correlations between risk factors for breast cancer and genetic instability in cancer patients-a clinical perspective study. Front. Genet., Vol. 8. 10.3389/fgene.2017.00236.
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  14. Paz, M.F.C.J., A.L. Gomes Jr., M.V.O.B. de Alencar, S. Tabrez and M.T. Islam et al., 2018. Effect of diets, familial history and alternative therapies on genomic instability of breast cancer patients. Applied Biochem. Biotechnol., (In Press). 10.1007/s12010-018-2918-9.
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  15. Paz, M.F.C.J., A.L. Gomes, M.T. Islam, S. Tabrez and N.R. Jabir et al., 2017. Assessment of chemotherapy on various biochemical markers in breast cancer patients. J. Cell. Biochem., 119: 2923-2928.
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  16. Ali, E.S., G.Y. Rychkov and G.J. Barritt, 2017. Metabolic disorders and cancer: hepatocyte store-operated Ca2+ channels in nonalcoholic fatty liver disease. Adv. Exp. Med. Biol., 993: 595-621.
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  17. Ali, E.S., J. Hua, C.H. Wilson, G.A. Tallis, F.H. Zhou, G.Y. Rychkov and G.J. Barritt, 2016. The glucagon-like peptide-1 analogue exendin-4 reverses impaired intracellular Ca2+ signalling in steatotic hepatocytes. Biochim. Biophys. Acta., 1863: 2135-2146.
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  18. Ali, E.S., H. Rajapaksha, J.M. Carr and N. Petrovsky, 2016. Norovirus drug candidates that inhibit viral capsid attachment to human histo-blood group antigens. Antiviral Res., 133: 14-22.
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  19. Wilson, C.H., E.S Ali, N. Scrimgeour, A.M Martin and J. Hua et al., 2015. Steatosis inhibits liver cell store-operated Ca2+ entry and reduces ER Ca2+ through a protein kinase c-dependent mechanism. Biochem. J., 466: 379-390.
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  20. Lundborg, M., E. Ali and G. Widmalm, 2013. An in silico virtual screening study for the design of norovirus inhibitors: fragment-based molecular docking and binding free energy calculations. Carbohydr. Res., 378: 133-138.
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  21. Chervona, Y., M.N. Hall, A. Arita, F. Wu and H. Sun et al., 2012. Associations between arsenic exposure and global posttranslational histone modifications among adults in Bangladesh. Cancer Epidemiol. Biomarkers Prev., 21: 2252-2260.
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