Dr. Deiske Adeliene Sumilat
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Dr. Deiske Adeliene Sumilat

Research Scientist
Sam Ratulangi University, Indonesia

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Biography

Faculty of Fisheries and Marine SciencesSam Ratulangi University Kampus Unsrat Bahu 95115.Manado Indonesia

Lingkungan 3, Malalayang 1. Malalayang Manado 95162 Indonesia

Area of Interest:

Pharmacology and Toxicology
100%
Marine Pharmaceutical Sciences
62%
Marine Natural Products
90%
Marine Invertebrates
75%
Marine Derived Fungi
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Wewengkang, D.S., H. Yamazaki, M. Takahashi, T. Togashi, H. Rotinsulu, D.A. Sumilat and M. Namikoshi, 2019. Production of an α-pyrone metabolite and microbial transformation of isoflavones by an Indonesian Streptomyces sp. J. Asian Natural Prod. Res., 10.1080/10286020.2019.1635588.
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  2. Sumilat, D.A., T. Oda, D.S. Wewengkang, M. Namikoshi and H. Yamazaki, 2019. Inhibition of interleukin-8 production in interleukin-1 stimulated human monocytic THP-1 cells by N, N didesmethylgrossularine-1 obtained from an ascidian Polycarpa aurata collected in North Sulawesi. IOP Confer. Ser.: Mater. Sci. Eng., Vol. 567. 10.1088/1757-899X/567/1/012021.
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  3. Sumilat, D.A., J.R. Rimper, E.T. Opa and D. Kurnia, 2019. The potential of marine ascidians as sources of natural antioxidant and antibacterial agents from Manado, North Sulawesi. Aquacult. Aquarium Conserv. Legisl., 12: 373-377.
    Direct Link  |  
  4. Sumilat, D.A., D.S. Wewengkang, H. Rotinsulu, H. Yamazaki, T. Oda, K. Ukai and M. Namikoshi, 2018. Bioactivity of extracts from ascidians collected in North Sulawesi as seeds of marine-derived drugs. Aquacult. Aquarium Conserv. Legisl., 11: 516-524.
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  5. Sinjal, C.A., R.M. Rompas, D.A. Sumilat and E. Suryanto, 2018. Antioxidant and photoprotective activity of brown seaweed from North Sulawesi coast. Int. J. ChemTech Res., 11: 121-133.
    CrossRef  |  
  6. Rotinsulu, H., H. Yamazaki, S. Sugai, N. Iwakura, D.S. Wewengkang, D.A. Sumilat and M. Namikoshi, 2018. Cladosporamide A, a new protein tyrosine phosphatase 1B inhibitor, produced by an Indonesian marine sponge-derived Cladosporium sp. J. Nat. Med., 72: 779-783.
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  7. Kapojos, M.M., D.B. Abdjul, H. Yamazaki, T. Ohshiro and H. Rotinsulu et al., 2018. Callyspongiamides A and B, sterol O-acyltransferase inhibitors, from the Indonesian marine sponge Callyspongia sp. Bioorg. Med. Chem. Lett., 28: 1911-1914.
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  8. Kapojos, M.M., D.B. Abdjul, H. Yamazaki, R. Kirikoshi and O. Takahashi et al., 2018. Protein tyrosine phosphatase 1B inhibitory polybromobiphenyl ethers and monocyclofarnesol-type sesquiterpenes from the Indonesian marine sponge Lamellodysidea cf. herbacea. Phytochem. Lett., 24: 10-14.
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  9. Abdjul, D.B., H. Yamazaki, S.I. Kanno, R. Kirikoshi and A. Tomizawa et al., 2018. Absolute structures of wedelolide derivatives and structure–activity relationships of protein tyrosine Phosphatase 1B inhibitory ent-kaurene diterpenes from aerial parts of Wedelia spp. collected in Indonesia and Japan. Chem. Pharm. Bull., 66: 682-687.
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  10. Tatsuta, T., M. Hosono, H. Rotinsulu, D.S. Wewengkang, D.A. Sumilat, M. Namikoshi and H. Yamazaki, 2017. Lissoclibadin 1, a polysulfur aromatic alkaloid from the Indonesian ascidian Lissoclinum cf. badium, induces caspase-dependent apoptosis in human colon cancer cells and suppresses tumor growth in nude mice. J. Natural Prod., 80: 499-502.
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  11. Sumilat, D.A., H. Yamazaki, S.I. Kanno, R. Saito, Y. Watanabe and M. Namikoshi, 2017. Biphenyl ether derivatives with protein tyrosine phosphatase 1B inhibitory activity from the freshwater fungus Phoma sp. J. Antibiot., 7: 331-333.
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  12. Sumilat, D.A., H. Yamazaki, K. Endo, H. Rotinsulu, D.S. Wewengkang, K. Ukai and M. Namikoshi, 2017. A new biphenyl ether derivative produced by Indonesian ascidian-derived Penicillium albobiverticillium. J. Natural Med., 71: 776-779.
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  13. Rotinsulu, H., H. Yamazaki, T. Miura, S. Chiba, D.S. Wewengkang, D.A. Sumilat and M. Namikoshi, 2017. A 2, 4'-linked tetrahydroxanthone dimer with protein tyrosine phosphatase 1B inhibitory activity from the Okinawan freshwater Aspergillus sp. J. Antibio., 70: 967-969.
    Direct Link  |  
  14. Maarisit, W., H. Yamazaki, S.I. Kanno, A. Tomizawa and H. Rotinsulu et al., 2017. A tetramic acid derivative with protein tyrosine phosphatase 1B inhibitory activity and a new nortriterpene glycoside from the Indonesian marine sponge Petrosia sp. Bioorg. Med. Chem. Lett., 27: 999-1002.
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  15. Maarisit, W., D.B. Abdjul, H. Yamazaki, H. Kato and H. Rotinsulu et al., 2017. Anti-mycobacterial alkaloids, cyclic 3-alkyl pyridinium dimers, from the Indonesian marine sponge Haliclona sp. Bioorg. Med. Chem. Lett., 27: 3503-3506.
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  16. Abdjul, D.B., H. Yamazaki, W. Maarisit, H. Rotinsulu and D.S. Wewengkang et al., 2017. Oleanane triterpenes with protein tyrosine phosphatase 1B inhibitory activity from aerial parts of Lantana camara collected in Indonesia and Japan. Phytochemistry, 144: 106-112.
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  17. Abdjul, D.B., H. Yamazaki, W. Maarisit, F. Losung and H. Rotinsulu et al., 2017. Eudesmanolide sesquiterpenes and protein tyrosine phosphatase 1B inhibitory ent-kaurene diterpenes from aerial parts of Indonesian Wedelia prostate. Phytochem. Lett., 20: 191-195.
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  18. Abdjul, D.B., H. Yamazaki, S.I. Kanno, D.S. Wewengkang and H. Rotinsulu et al., 2017. Furanoterpenes, new types of protein tyrosine phosphatase 1B inhibitors, from two Indonesian marine sponges, Ircinia and Spongia spp. Bioorg. Med. Chem. Lett., 27: 1159-1161.
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  19. Abdjul, D.B., H. Yamazaki, S.I. Kanno, A. Tomizawa and H. Rotinsulu et al., 2017. An anti-mycobacterial bisfunctionalized sphingolipid and new bromopyrrole alkaloid from the Indonesian marine sponge Agelas sp. J. Natural Med., 71: 531-536.
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  20. Yamazaki, H., W. Nakayama, O. Takahashi, R. Kirikoshi and Y. Izumikawa et al., 2015. Verruculides A and B, two new protein tyrosine phosphatase 1B inhibitors from an Indonesian ascidian-derived Penicillium verruculosum. Bioorg. Med. Chem. Lett., 25: 3067-3090.
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  21. Yamazaki, H., O. Takahashi, S.I. Kanno, T. Nakazawa and S. Takahashi et al., 2015. Absolute structures and bioactivities of euryspongins and eurydiene obtained from the marine sponge Euryspongia sp. collected at Iriomote Island. Bioorg. Med. Chem., 23: 797-802.
    CrossRef  |  Direct Link  |  
  22. Yamazaki, H., T. Nakazawa, D.A. Sumilat, O. Takahashi, K. Ukai, S. Takahashi and M. Namikoshi, 2013. Euryspongins A-C, three new unique sesquiterpenes from a marine sponge Euryspongia sp. Bioorg. Med. Chem. Lett., 23: 2151-2154.
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  23. Yamazaki, H., D.A. Sumilat, S.I. Kanno, K. Ukai and H. Rotinsulu et al., 2013. A polybromodiphenyl ether from an Indonesian marine sponge Lamellodysidea herbacea and its chemical derivatives inhibit protein tyrosine phosphatase 1B, an important target for diabetes treatment. J. Natural Med., 67: 730-735.
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