Area of Interest:

Pharmacology and Toxicology

100%

Dose Individualization

62%

Clinical Trial Simulations

90%

Pharmacotherapeutics

75%

Drug Development

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
0

Abstracts
0

Selected Publications

Lee, J.B., A. Zgair, D.A. Taha, X. Zang and L. Kagan et al., 2017. Quantitative analysis of lab-to-lab variability in Caco-2 permeability assays. Eur. J. Pharm. Biopharm., 114: 38-42.
CrossRef |
Jeon, J.S., J.J. Oh, H.C. Kwak, H.Y. Yun and H.C. Kim et al., 2017. Age-related changes in sulfur amino acid metabolism in male C57bl/6 mice. Biomol. Ther., 10.4062/biomolther.2017.054.
CrossRef |
Chang, M.J., B. Jin, J.W. Chae, H.Y. Yun and E.S. Kim et al., 2017. Population pharmacokinetics of moxifloxacin, cycloserine, p-aminosalicylic acid and kanamycin for the treatment of multi-drug-resistant tuberculosis. Int. J. Antimicrob. Agents, 49: 677-687.
CrossRef |
Chae, J.W., H.Y. Yun, H.Y. Eom, E.J. Jeong, T.S. Koo, K.I. Kwon and J.H. Lee, 2017. Development of a LC-MS/MS method for the determination of CKD-712 in rat plasma: Application to a pharmacokinetic study in rats. J. Chromatogr. B, 1061: 123-127.
CrossRef |
Chae, J.W., Y.L. Teo, H.K. Ho, J. Lee and H.M. Back et al., 2016. BSA and ABCB1 polymorphism affect the pharmacokinetics of sunitinib and its active metabolite in Asian mRCC patients receiving an attenuated sunitinib dosing regimen. Cancer Chemother. Pharmacol., 78: 623-632.
Direct Link |
Noh, K., S.S. Beom, K. Kwang-il, Y. Hwi-yeol, K. Eunyoung, C.J. Tae and K. Wonku, 2015. Absolute bioavailability and metabolism of aceclofenac in rats. Arch. Pharm. Res., 38: 68-72.
CrossRef | Direct Link |
Noh, K., J. Yoo-Jeong, K. Kwang-il, K. Eunyoung, C.J. Tae, Y. Hwi-yeol and K. Wonku, 2015. Quantitative determination of amisulpride in rat plasma by HPLC-MS/MS. Arch. Pharmacal Res., 38: 63-67.
CrossRef | PubMed | Direct Link |
Kim, M.G., I.W. Kim, B. Choi, N. Han, H.Y. Yun, S. Park and J.M. Oh, 2015. Population pharmacokinetics of cyclosporine in hematopoietic stem cell transplant patients: Consideration of genetic polymorphisms. Ann. Pharmacother., 49: 622-630.
CrossRef |
Hyun-moon, B., S. Byungjeong, C. Jung-woo, Y. Hwi-yeol, Y.M. Jin and K. Kwang-il, 2015. Determination of matrine in rat plasma after oral administration of novel korean herbal medicine KIOM-MA128 and application of PK. J. Anal. Methods Chem., 10.1155/2015/431632.
CrossRef | Direct Link |
Hyun-moon, B., L. Jong-Hwa, Y. Hwi-yeol and K. Kwang-il, 2015. Development of QTc prolongation model incorporating circadian rhythm using harmonic model. Xenobiotica, 45: 420-427.
CrossRef | Direct Link |
Chang, M.J., J.W. Chae, H.Y. Yun, J.I. Lee and H.D. Choi et al., 2015. Effects of type 2 diabetes mellitus on the population pharmacokinetics of rifampin in tuberculosis patients. Tuberculosis, 95: 54-59.
CrossRef |
Back, H.M., J.H. Lee, J.W. Chae, B. Song, J.W. Seo, H.Y. Yun and K.I. Kwon, 2015. A novel HPLC-MS/MS method for the simultaneous determination of astemizole and its major metabolite in dog or monkey plasma and application to pharmacokinetics. J. Pharm. Biomed. Anal., 114: 121-126.
CrossRef |
Jung-woo, C., S. Jeong-won, M. Bimit, Y. Hwi-yeol and K. Kwang-il et al., 2014. A simple pharmacokinetic model of alendronate developed using plasma concentration and urine excretion data from healthy men. Drug Dev. Ind. Pharm., 44: 1325-1329.
CrossRef | Direct Link |
Hwi-yeol, Y., K. Wonku, L. Buyng-yo, P. Sunkyung, Y. Young-Ran, Y.M. Jun and K. Kwang-il, 2014. Semi-Mechanistic modelling and simulation of inhibition of platelet aggregation by antiplatelet agents. Basic Clin. Pharmacol. Toxicol., 115: 352-359.
CrossRef | PubMed | Direct Link |