Dr. Soo Wan Chae
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Dr. Soo Wan Chae

Professor
Chonbuk National University,South Korea

Highest Degree
PostDoc. in Physiology from Cornell University Medical School, Korea

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Area of Interest:

Pharmacology and Toxicology
100%
Clinical Dentistry
62%
Medicine
90%
Health
75%
Pharmacology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Park, B.M., H. Chun, S.W. Chae and S.H. Kim, 2017. Fermented garlic extract ameliorates monocrotaline-induced pulmonary hypertension in rats. J. Funct. Foods, 30: 247-253.
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  2. Lee, H.Y., M.R. Oh, E.S. Jung, Y.S. Lee and D.S. Kim et al., 2017. Mulberry and its main components protect against oxidized low-density lipoprotein-induced endothelial nitric oxide synthase uncoupling. J. Funct. Foods, 29: 295-302.
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  3. Kim, H., Y.J. Kim, H.Y. Jeong, J.Y. Kim, E.K. Choi, S.W. Chae and O. Kwon, 2017. A standardized extract of the fruit of Hovenia dulcis alleviated alcohol-induced hangover in healthy subjects with heterozygous ALDH2: A randomized, controlled, crossover trial. J. Ethnopharmacol., 209: 167-174.
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  4. Khan, M.M., B.Q. Tran, Y.J. Jang, S.H. Park and W.E. Fondrie et al., 2017. Assessment of the therapeutic potential of persimmon leaf extract on prediabetic subjects. Mol. Cells, 40: 466-475.
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  5. Bae, U.J., M.R. Oh, T.S. Jung, S.W. Chae and B.H. Park, 2017. Decursin and decursinol angelate-rich Angelica gigas Nakai extract suppresses de novo lipogenesis and alleviates nonalcoholic fatty liver disease and dyslipidemia in mice fed a high fat diet. J. Funct. Foods, 31: 208-216.
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  6. Bae, U.J., M.R. Oh, J. Park, J.S. Park and E.Y. Bae et al., 2017. Supplementation with Lycium chinense fruit extract attenuates methionine choline-deficient diet-induced steatohepatitis in mice. J. Funct. Foods, 31: 1-8.
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  7. Tamang, J.P., D.H. Shin, S.J. Jung and S.W. Chae, 2016. Functional properties of microorganisms in fermented foods. Front. Microbiol., Vol. 7. 10.3389/fmicb.2016.00578.
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  8. Park, E.O., M.R. Oh, E.K. Choi, D.H. Shin and J.K. Doo et al., 2016. Mixed grain containing giant embryonic brown rice improves postprandial glycaemic response in healthy subjects. Nutr. Dietet., 73: 132-138.
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  9. Park, C.M., H.M. Kim, D.H. Kim, H.J. Han and H. Noh et al., 2016. Ginsenoside re inhibits osteoclast differentiation in mouse bone marrow-derived macrophages and zebrafish scale model. Mol. Cells, 39: 855-861.
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  10. Park, B.M., S.A. Cha, H.Y. Kim, D.K. Kang and K. Yuan et al., 2016. Fermented garlic extract decreases blood pressure through nitrite and sGC-cGMP-PKG pathway in spontaneously hypertensive rats. J. Funct. Foods, 22: 156-165.
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  11. Lee, J.H., W.S. Chong, J.K. Park, T.S. Park, S.W. Chae and M.G. Kim, 2016. Rooibos™: Automated schedule broadcast software for clinical pharmacology studies. Transl. Clin. Pharmacol., 24: 127-131.
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  12. Kwak, D.H. and S.W. Chae, 2016. Solid thickening and methane production of livestock wastewater using dissolved carbon dioxide flotation. Water Qual. Res. J., 51: 17-25.
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  13. Jung, S.J., M.J. Kim and S.W. Chae, 2016. Quality and functional characteristics of kimchi made with organically cultivated young Chinese cabbage (olgari-baechu). J. Ethnic Foods, 3: 150-158.
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  14. Jeon, J.Y., S.W. Chae and M.G. Kim, 2016. Population pharmacokinetics of aripiprazole in healthy Korean subjects. Int. J. Clin. Pharmacol. Therapeut., 54: 293-304.
    CrossRef  |  PubMed  |  Direct Link  |  
  15. Jang, S.H., J. Park, S.H. Jang, S.W. Chae and S.J. Jung et al., 2016. In vitro stimulation of NK cells and lymphocytes using an extract prepared from mycelial culture of Ophiocordyceps sinensis. Immune Network, 16: 140-145.
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  16. Chung, Y.C., Y. Cui, M.G. Kim, Y.J. Kim, K.H. Lee and S.W. Chae, 2016. Early predictors of a clinical response at 8 weeks in patients with first-episode psychosis treated with paliperidone ER. J. Psychopharmacol., 30: 810-818.
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  17. Choi, E.K., M.H. Ko, S.H. Park, K.C. Ha and H.I. Baek et al., 2016. Eriobotrya japonica improves cognitive function in healthy adolescents: A 12-week, randomized double-blind, placebo-controlled clinical trial. Int. J. Pharmacol., 12: 370-378.
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  18. Baek, H.I., K.C. Ha, H.M. Kim, E.K. Choi and E.O. Park et al., 2016. Randomized, double-blind, placebo-controlled trial of Ficus carica paste for the management of functional constipation. Asia Pac. J. Clin. Nutr., 25: 487-496.
  19. Bae, U.J., E.K. Choi, M.R. Oh, S.J. Jung and J. Park et al., 2016. Angelica gigas ameliorates hyperglycemia and hepatic steatosis in C57BL/KsJ-db/db mice via activation of AMP-activated protein kinase signaling pathway. Am. J. Chin. Med., 44: 1627-1638.
  20. Yook, J.S., M. Kim, P.B. Pichiah, S.J. Jung, S.W. Chae and Y.S. Cha, 2015. The antioxidant properties and inhibitory effects on HepG2 cells of chicory cultivated using three different kinds of fertilizers in the absence and presence of pesticides. Molecules, 20: 12061-12075.
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  21. Park, S.Y., S.J. Jung, K.C. Ha, H.S. Sin, S.H. Jang, H.J. Chae and S.W. Chae, 2015. Anti-inflammatory effects of Cordyceps mycelium (Paecilomyces hepiali, CBG-CS-2) in Raw264.7 murine macrophages. Orient. Pharm. Exp. Med., 15: 7-12.
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  22. Lim, J.H., E.S. Jung, E.K. Choi, D.Y. Jeong and S.W. Jo et al., 2015. Supplementation with Aspergillus oryzae-fermented kochujang lowers serum cholesterol in subjects with hyperlipidemia. Clin. Nutr., 34: 383-387.
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  23. Lee, H.Y., S.H. Park, S.W. Chae, N.K. Soung and M.J. Oh et al., 2015. Aqueous ginseng extract has a preventive role in RANKL-induced osteoclast differentiation and estrogen deficiency-induced osteoporosis. J. Funct. Foods, 13: 192-203.
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  24. Jung, S.J., M.G. Kim, T.S. Park, Y.G. Kim, W.O. Song and S.W. Chae, 2015. Rice-based Korean meals (bibimbap and kimbap) have lower glycemic responses and postprandial-triglyceride effects than energy-matched Western meals. J. Ethnic Foods, 2: 154-161.
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  25. Jang, S.H., S.H. Kim, H.Y. Lee, S.H. Jang and H. Jang et al., 2015. Immune-modulating activity of extract prepared from mycelial culture of Chinese caterpillar mushroom, Ophiocordyceps sinensis (Ascomycetes). Int. J. Med. Mushrooms, 17: 1189-1199.
    CrossRef  |  PubMed  |  Direct Link  |  
  26. Choi, E.K., S.H. Park, K.C. Ha, S.O. Noh and S.J. Jung et al., 2015. Clinical trial of the hypolipidemic effects of a brown alga ecklonia cava extract in patients with hypercholesterolemia. Int. J. Pharmacol., 11: 798-805.
  27. Chae, S.W., F. Mitsunaga, S.J. Jung, K.C. Ha, H.S. Sin, S.H. Jang and S. Nakamura, 2015. Mechanisms underlying the antifatigue effects of the mycelium extract of Cordyceps (Paecilomyces hepiali, CBG-CS-2) in mice in the forced swimming test. Food Nutr. Sci., 6: 287-298.
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  28. Baek, H.I., S.Y. Jung, K.C. Ha, H.M. Kim and E.K. Choi et al., 2015. Effect of Chongkukjang on histamine-induced skin wheal response: A randomized, double-blind, placebo-controlled trial. J. Ethnic Foods, 2: 52-57.
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  29. Baek, H.I., S.W. Kim, K.C. Ha, H.M. Kim and B.O. So et al., 2015. Effectiveness of Hizikia fusiformis extract on erosive gastritis: A 4-week, randomized, double-blind and placebo-controlled trial. Int. J. Pharmacol., 11: 719-725.
  30. Bae, U.J., S.H. Park, S.Y. Jung, B.H. Park and S.W. Chae, 2015. Hypoglycemic effects of aqueous persimmon leaf extract in a murine model of diabetes. Mol. Med. Rep., 12: 2547-2554.
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  31. Yadav, R.K., S.W.Chae, H.R. Kim and H.J. Chae, 2014. Endoplasmic reticulum stress and cancer. J. Cancer Prev., 19: 75-88.
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  32. Park, S.H., T.L. Huh, S.Y. Kim, M.R. Oh, P.B.T. Pichiah, S.W. Chae and Y.S. Cha, 2014. Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): A randomized, double-blind, placebo-controlled trial. Obesity, 22: 63-71.
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  33. Park, S.H., M.R. Oh, E.K. Choi, M.G. Kim and K.C. Ha et al., 2014. An 8-wk, randomized, double-blind, placebo-controlled clinical trial for the antidiabetic effects of hydrolyzed ginseng extract. J. Ginseng Res., 38: 239-243.
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  34. Oh, M.R., S.H. Park, S.Y. Kim, H.I. Back and M.G. Kim et al., 2014. Postprandial glucose-lowering effects of fermented red ginseng in subjects with impaired fasting glucose or type 2 diabetes: A randomized, double-blind, placebo-controlled clinical trial. BMC Complement. Altern. Med., Vol. 14. 10.1186/1472-6882-14-237.
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  35. Jung, S.J., S.H. Park, E.K. Choi, Y.S. Cha and B.H. Cho et al., 2014. Beneficial effects of Korean traditional diets in hypertensive and type 2 diabetic patients. J. Med. Food, 17: 161-171.
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  36. Jung, S.J., B.O. So, S.W. Shin, S.O. Noh, E.S. Jung and S.W. Chae, 2014. Physiochemical and quality characteristics of young radish (Yulmoo) kimchi cultivated by organic farming. J. Korean Soc. Food Sci. Nutr., 43: 1197-1206.
  37. Jung, E.S., S.H. Park, E.K. Choi, B.H. Ryu and B.H. Park et al., 2014. Reduction of blood lipid parameters by a 12-wk supplementation of aged black garlic: A randomized controlled trial. Nutrition, 30: 1034-1039.
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  38. Jeon, J.Y., S.Y. Lee, Y.J. Im, E.Y. Kim and Y. Kim et al., 2014. Comparison of the pharmacokinetics, safety and tolerability of vitamin D3 in DP-R206 (150-mg Ibandronate/24,000-IU vitamin D3 tablet) and as monotherapy (24,000 IU) in healthy male Korean adults. Clin. Therapeut., 36: 48-57.
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  39. Chung, Y.C., H.M. Jin, Y. Cui, D.S. Kim and J.M. Jung et al., 2014. Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults. J. Funct. Foods, 10: 465-474.
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  40. Chae, S.W., F. Mitsunaga, S.J. Jung, K.C. Ha and H.S. Sin et al., 2014. Nutrigenomic study on immunomodulatory function of cordyceps mycelium extract (Paecilomyces hepiali) in mitomycin C-treated mice. Food Nutr. Sci., 5: 2217-2224.
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  41. Chae, S.W., B.O. So and B.C. Ju, 2014. A study on establishing an analysis system for an agro-medical convergence R&D project. Korean J. Tourism Res., 29: 155-175.
  42. Cha, Y.S., Y. Park, M. Lee, S.W. Chae, K. Park, Y. Kim and H.S. Lee, 2014. Doenjang, a Korean fermented soy food, exerts antiobesity and antioxidative activities in overweight subjects with the PPAR-γ2 C1431T polymorphism: 12-week, double-blind randomized clinical trial. J. Med. Food, 17: 119-127.
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  43. Lee, M., S.W. Chae, Y.S. Cha, M.S. Cho, H.Y. Oh and M.K. Kim, 2013. Development of a Korean Diet Score (KDS) and its application assessing adherence to Korean healthy diet based on the Korean Food Guide Wheels. Nutr. Res. Pract., 7: 49-58.
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  44. Kwak, D.H., M.S. Kim, J.S. Kim, Y.Y. Oh and S.O. Noh et al., 2013. Evaluation of methane yield on mesophilic-dry anaerobic digestion of piggery manure mixed with chaff for agricultural area. Adv. Chem. Eng. Sci., 3: 227-235.
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  45. Kim, Y., S.H. Han, J.Y. Jeon, M.H. Hwang and Y.J. Im et al., 2013. Validation of LC-MS/MS method for determination of ginsenoside Rg1 in human plasma. Anal. Sci. Technol., 26: 221-227.
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  46. Kim, Y., N. Ha, S.H. Han, J.Y. Jeon and M. Hwang et al., 2013. Confirmation of schizandrin as a marker compound in Jangsu omija powder. J. Korean Soc. Food Sci. Nutr., 42: 244-248.
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  47. Kim, S.W., K.C. Ha, E.K. Choi, S.Y. Jung and M.G. Kim et al., 2013. The effectiveness of fermented turmeric powder in subjects with elevated alanine transaminase levels: A randomised controlled study. BMC Complementary Altern. Med., Vol. 13. 10.1186/1472-6882-13-58.
    CrossRef  |  
  48. Kim, J.S., Y. Kim, S.H. Han, J.Y. Jeon and M. Hwang et al., 2013. Development and validation of an LC-MS/MS method for determination of compound K in human plasma and clinical application. J. Ginseng Res., 37: 135-141.
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  49. Jeon, J.Y., Y.J. Im, Y. Kim, S.M. Han and M.J. Jo et al., 2013. Pharmacokinetic properties and bioequivalence of candesartan cilexetil in Korean healthy volunteers. Drug Dev. Ind. Pharm., 39: 1296-1299.
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  50. Im, J., C. Hwang, Y. Lim, S. Chae and B. Cho et al., 2013. Acquisition of voice signal using PVDF vibration sensor for finding relationship between voices and energy expenditure. Int. J. Bio-Sci. Bio-Technol., 5: 103-112.
    Direct Link  |  
  51. Huang, G.B., T. Zhao, S.S. Muna, H.M. Jin and J.I. Park et al., 2013. Therapeutic potential of Gastrodia elata Blume for the treatment of Alzheimer's disease. Neural Regener. Res., 8: 1061-1070.
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  52. Cha, Y.S., S.R. Kim, J.A. Yang, H.I. Back and M.G. Kim et al., 2013. Kochujang, fermented soybean-based red pepper paste, decreases visceral fat and improves blood lipid profiles in overweight adults. Nutr. Metab., Vol. 10. 10.1186/1743-7075-10-24.
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  53. Oh, H.G., H.Y. Lee, J.H. Kim, Y.R. Kang and D.I. Moon et al., 2012. Effects of male silkworm pupa powder on the erectile dysfunction by chronic ethanol consumption in rats. Lab. Anim. Res., 28: 83-90.
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  54. Lee, M., S. Chae, Y. Cha and Y. Park, 2012. Supplementation of Korean fermented soy paste Doenjang reduces visceral fat in overweight subjects with mutant uncoupling protein-1 allele. Nutr. Res., 32: 8-14.
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  55. Lee, H.Y., J.H. Kim, H.W. Jeung, C.U. Lee and D.S. Kim et al., 2012. Effects of Ficus carica paste on loperamide-induced constipation in rats. Food Chem. Toxicol., 50: 895-902.
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  56. Lee, G.H., H.R. Kim, S.Y. Han, B. Bhandary and D.S. Kim et al., 2012. Gastrodia elata blume and its pure compounds protect BV-2 microglial-derived cell lines against β-amyloid: The involvement of GRP78 and CHOP. Biol. Res., 45: 403-410.
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  57. Lee, C.S., J.H. Lee, M. Oh, K.M. Choi and M.R. Jeong et al., 2012. Preventive effect of Korean red ginseng for acute respiratory illness: A randomized and double-blind clinical trial. J. Korean Med. Sci., 27: 1472-1478.
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  58. Kang, Y.R., H.Y. Lee, J.H. Kim, D.I. Moon and M.Y. Seo et al., 2012. Anti-obesity and anti-diabetic effects of Yerba Mate (Ilex paraguariensis) in C57BL/6J mice fed a high-fat diet. Lab. Anim. Res., 28: 23-29.
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  59. Ha, K.C., M.G. Kim, M.R. Oh, E.K. Choi and H.I. Back et al., 2012. A placebo-controlled trial of Korean red ginseng extract for preventing influenza-like illness in healthy adults. BMC Complementary Altern. Med., Vol. 12. 10.1186/1472-6882-12-10.
    CrossRef  |  Direct Link  |  
  60. Chung, Y.C., C.H. Park, H.K. Kwon, Y.M. Park and Y.S. Kim et al., 2012. Improved cognitive performance following supplementation with a mixed-grain diet in high school students: A randomized controlled trial. Nutrition, 28: 165-172.
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  61. Cha, Y.S., J. Yang, H.I. Back, S.R. Kim and M.G. Kim et al., 2012. Visceral fat and body weight are reduced in overweight adults by the supplementation of Doenjang, a fermented soybean paste. Nutr. Res. Pract., 6: 520-526.
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  62. Bhandary, B., H.Y. Lee, H.I. Back, S.H. Park and M.G. Kim et al., 2012. Immature Rubus coreanus shows a free radical-scavenging effect and inhibits cholesterol synthesis and secretion in liver cells. Indian J. Pharmaceut. Sci., 74: 211-216.
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  63. Bhandary, B., G.H. Lee, B.O. So, S.Y. Kim and M.G. Kim et al., 2012. Rubus coreanus inhibits oxidized-LDL uptake by macrophages through regulation of JNK activation. Am. J. Chin. Med., 40: 967-978.
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  64. Bhandary, B., G.H. Lee, A. Marahatta, H.Y. Lee and S.Y. Kim et al., 2012. Water extracts of immature Rubus coreanus regulate lipid metabolism in liver cells. Biol. Pharmaceut. Bull., 35: 1907-1913.
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  65. Bhandary, B., C.S. Piao, D.S. Kim, G.H. Lee, S.W. Chae, H.R. Kim and H.J. Chae, 2012. The protective effect of rutin against ischemia/reperfusion-associated hemodynamic alteration through antioxidant activity. Arch. Pharmacal Res., 35: 1091-1097.
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  66. Piao, C.S., D.S. Kim, K.C. Ha, H.R. Kim, H.J. Cha and S.W. Chae, 2011. The protective effect of epigallocatechin-3 gallate on ischemia/reperfusion injury in isolated rat hearts: An ex vivo approach. Korean J. Physiol. Pharmacol., 15: 259-266.
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  67. Oh, H.G., J.W. Park, Y.R. Kang, J.H. Kim and M.Y. Seo et al., 2011. Improving effects of multigrain feed on endurance. J. Korean Soc. Food Sci. Nutr., 40: 1700-1707.
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  68. Oh, H.G., H.Y. Lee, M.Y. Seo, Y.R. Kang and J.H. Kim et al., 2011. Effects of Ficus carica paste on constipation induced by a high-protein feed and movement restriction in beagles. Lab. Anim. Res., 27: 275-281.
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  69. Lee, G.H., D.S. Kim, M.J. Chung, S.W. Chae, H.R. Kim and H.J. Chae, 2011. Lysyl oxidase-like-1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved. Oncol. Lett., 2: 831-838.
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  70. Kwon, D.Y., H.J. Yang, M.J. Kim, H.J. Kang and H.J. Kim et al., 2011. Influence of the Chungkookjang on histamine-induced wheal and flare skin response: A randomized, double-blind, placebo controlled trial. BMC Complement. Altern. Med., Vol. 11. 10.1186/1472-6882-11-125.
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  71. Kim, M.G., K.C. Ha, H.I. Back, S.Y. Kim and J.W. Kim et al., 2011. Effects of polycan on bone metabolism in healthy perimenopausal women: A 12-week randomized, double-blind, placebo-controlled study. Korean J. Clin. Pharm., 21: 297-304.
  72. Jung, S.J., S.W. Chae, H.S. Sohn, S.B. Kim and J.O. Rho et al., 2011. Actual status of constipation and life factors affecting constipation by diagnosis of Rome in female university students in Korea. Korean J. Nutr., 44: 428-442.
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  73. Jeon, J.Y., M. Hwang, Y.J. Im, Y. Kim and S.M. Han et al., 2011. Pharmacokinetic propertiese of entecavir 1 mg in Korean healthy volunteers. Korean J. Clin. Pharm., 21: 224-227.
  74. Back, H.I., S.R. Kim, J.A. Yang, M.G. Kim, S.W. Chae and Y.S. Cha, 2011. Effects of Chungkookjang supplementation on obesity and atherosclerotic indices in overweight/obese subjects: A 12-week, randomized, double-blind, placebo-controlled clinical trial. J. Med. Food, 14: 532-537.
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