Dr. Byeong  Jae Lee

Dr. Byeong Jae Lee

Professor
Seoul National University Hospital, South Korea


Highest Degree
Ph.D. in Molecular Genetics from Seoul National University Hospital, South Korea

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Area of Interest:

Biomedical Sciences
100%
Molecular Biology
62%
Genetics
90%
Medicine
75%
Biological Sciences
55%

Selected Publications

  1. Na, J., J. Jung, J. Bang, Q. Lu and B.A. Carlson et al., 2018. Selenophosphate synthetase 1 and its role in redox homeostasis, defense and proliferation. Free Radic. Biol. Med., 127: 190-197.
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  2. Carlson, B.A., B.J. Lee, P.T. Tsuji, P.R. Copeland, U. Schweizer, V.N. Gladyshev and D.L. Hatfield, 2018. Selenocysteine tRNA[Ser]Sec, the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification and Sequencing. In: Selenoproteins: Methods and Protocols, Chavatte, L. (Ed.). Humana Press, New York, USA., ISBN: 9781493972579, pp: 43-60.
  3. Wu, C., H. Liu, F.E. Zhang, W. Shao and L. Yang et al., 2017. Long noncoding RNA expression profile reveals lncRNAs signature associated with extracellular matrix degradation in kashin-beck disease. Scient. Rep., Vol. 7. 10.1038/s41598-017-17875-0.
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  4. Tobe, R., B.A. Carlson, J.H. Huh, N.P. Castro and X.M. Xu et al., 2016. Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals. Biochem. J., 473: 2141-2154.
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  5. Gladyshev, V.N., E.S. Arner, M.J. Berry, R. Brigelius-Flohe and E.A. Bruford et al., 2016. Selenoprotein gene nomenclature. J. Biol. Chem., 291: 24036-24040.
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  6. Tobe, R., B.A. Carlson, P.A. Tsuji, B.J. Lee, V.N. Gladyshev and D.L. Hatfield, 2015. Differences in redox regulatory systems in human lung and liver tumors suggest different avenues for therapy. Cancers, 7: 2262-2276.
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  7. Carlson, B.A., R. Tobe, P.A. Tsuji, M.H. Yoo and L. Feigenbaum et al., 2015. Selenocysteine tRNA[Ser]Sec: The Central Component of Selenoprotein Biosynthesis. In: Diversity of Selenium Functions in Health and Disease, Brigelius-Flohe, R. and H. Sies (Eds.). CRC Press, USA., ISBN-13: 9781482251272, pp: 55-82.
  8. Ben, S.B., B. Peng, G.C. Wang, C. Li and H.F. Gu et al., 2015. Overexpression of selenoprotein SelK in BGC-823 cells inhibits cell adhesion and migration. Biochemistry (Moscow), 80: 1344-1353.
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  9. Bang, J., M. Jang, J.H. Huh, J.W. Na and M. Shim et al., 2015. Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway. Biochem. Biophys. Res. Commun., 456: 884-890.
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  10. Bang, J., J.H. Huh, J.W. Na, Q. Lu and B.A. Carlson et al., 2015. Cell proliferation and motility are inhibited by G1 phase arrest in 15-kDa selenoprotein-deficient Chang liver cells. Mol. Cells, 38: 457-465.
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  11. Kim, M., Z. Chen, M.S. Shim, M.S. Lee and J.E. Kim et al., 2013. SUMO modification of NZFP mediates transcriptional repression through TBP binding. Mol. Cells, 35: 70-78.
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  12. Lee, K.H., H. Kim, B.J. Lee and K. Park, 2012. Identification of methylation-dependent regulatory elements for intergenic miRNAs in human H4 cells. Biochem. Biophys. Res. Commun., 420: 391-396.
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  13. Shim, M.S., J.Y. Kim, K.H. Lee, H.K. Jung and B.A. Carlson et al., 2011. l(2)01810 is a novel type of glutamate transporter that is responsible for megamitochondrial formation. Biochem. J., 439: 277-286.
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  14. Lee, K.H., M.S. Shim, J.Y. Kim, H.K. Jung and E. Lee et al., 2011. Drosophila selenophosphate synthetase 1 regulates vitamin B6 metabolism: Prediction and confirmation. BMC Genom., Vol. 12. 10.1186/1471-2164-12-426.
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  15. Kim, J.Y., B.A. Carlson, X.M. Xu, Y. Zeng and S. Chen et al., 2011. Inhibition of selenocysteine tRNA[Ser]Sec aminoacylation provides evidence that aminoacylation is required for regulatory methylation of this tRNA. Biochem. Biophys. Res. Commun., 409: 814-819.
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  16. Ben, S.B., Q.Y. Wang, L. Xia, J.Z. Xia and J. Cui et al., 2011. Selenoprotein dSelK in Drosophila elevates release of Ca2+ from endoplasmic reticulum by upregulating expression of inositol 1,4,5-tris-phosphate receptor. Biochemistry (Moscow), 76: 1030-1036.
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  17. Kim, J.Y., K.H. Lee, M.S. Shim, H. Shin and X.M. Xu et al., 2010. Human selenophosphate synthetase 1 has five splice variants with unique interactions, subcellular localizations and expression patterns. Biochem. Biophys. Res. Commun., 397: 53-58.
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  18. Kim, E.A., J.E. Kim, K.S. Sung, D.W. Choi, B.J. Lee and C.Y. Choi, 2010. Homeodomain-Interacting Protein Kinase 2 (HIPK2) targets β-catenin for phosphorylation and proteasomal degradation. Biochem. Biophys. Res. Commun., 394: 966-971.
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  19. Shim, M.S., J.Y. Kim, H.K. Jung, K.H. Lee and X.M. Xu et al., 2009. Elevation of glutamine level by selenophosphate synthetase 1 knockdown induces megamitochondrial formation in Drosophila cells. J. Biol. Chem., 284: 32881-32894.
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  20. Kim, H., B.J. Lee, M.H. Lee, S.G. Hong and P.D. Ryu, 2009. Mechanisms of selective antimicrobial activity of gaegurin 4. Korean J. Physiol. Pharmacol., 13: 39-47.
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  21. Carlson, B.A., B.J. Lee and D.L. Hatfield, 2008. Ribosomal frameshifting in response to hypomodified tRNAs in Xenopus oocytes. Biochem. Biophys. Res. Commun., 375: 86-90.
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  22. Kim, S.S., M.S. Shim, J. Chung, D.Y. Lim and B.J. Lee, 2007. Purification and characterization of antimicrobial peptides from the skin secretion of Rana dybowskii. Peptides, 28: 1532-1539.
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  23. Carlson, B.A., M.E. Moustafa, A. Sengupta, U. Schweizer and R. Shrimali et al., 2007. Selective restoration of the selenoprotein population in a mouse hepatocyte selenoproteinless background with different mutant selenocysteine tRNAs lacking Um34. J. Biol. Chem., 282: 32591-32602.
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  24. Park, E., Y.K. Chae, J.Y. Lee, B.J. Lee and Y.M. Kim, 2006. Expression and purification of a cathelicidin-derived antimicrobial peptide, CRAMP. J. Microbiol. Biotechnol., 16: 1429-1433.
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  25. Lee, S.M., M. Kim, E.P. Moon, B.J. Lee, J.Y. Choi and J. Kim, 2006. Genomic structure and transcriptional studies on the mouse ribosomal protein S3 gene: Expression of U15 small nucleolar RNA. Gene, 368: 12-20.
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  26. Eun, S.Y., H.K. Jang, S.K. Han, P.D. Ryu, B.J. Lee, K.H. Han and S.J. Kim, 2006. A helix-induced oligomeric transition of gaegurin 4, an antimicrobial peptide isolated from a Korean frog. Mol. Cells, 21: 229-236.
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  27. Chen, C.L., M.S. Shim, J. Chung, H.S. Yoo and J.M. Ha et al., 2006. G-rich, a Drosophila selenoprotein, is a Golgi-resident type III membrane protein. Biochem. Biophys. Res. Commun., 348: 1296-1301.
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  28. Kim, S., S.S. Kim and B.J. Lee, 2005. Correlation between the activities of α-helical antimicrobial peptides and hydrophobicities represented as RP HPLC retention times. Peptides, 26: 2050-2056.
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  29. Won, H.S., S.S. Kim, S.J. Jung, W.S. Son, B. Lee and B.J. Lee, 2004. Structure-activity relationships of antimicrobial peptides from the skin of Rana esculenta inhabiting in Korea. Mol. Cells, 17: 469-476.
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  30. Kim, H.J., S.S. Kim, M.H. Lee, B.J. Lee and P.D. Ryu, 2004. Role of C-terminal heptapeptide in pore-forming activity of antimicrobial agent, gaegurin 4. J. Pept. Res., 64: 151-158.
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  31. Jin, J.S., S. Baek, H. Lee, M.Y. Oh and Y.E. Koo et al., 2004. A DNA replication-related element downstream from the initiation site of Drosophila selenophosphate synthetase 2 gene is essential for its transcription. Nucleic Acids Res., 32: 2482-2493.
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  32. Carlson, B.A., S.V. Novoselov, E. Kumaraswamy, B.J. Lee, M.R. Anver, V.N. Gladyshev and D.L. Hatfield, 2004. Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function. J. Biol. Chem., 279: 8011-8017.
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  33. Kwon, S.Y., P. Badenhorst, F.J. Martin-Romero, B.A. Carlson and B.M. Paterson et al., 2003. The Drosophila selenoprotein BthD is required for survival and has a role in salivary gland development. Mol. Cell. Biol., 23: 8495-8504.
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  34. Kumaraswamy, E., B.A. Carlson, F. Morgan, K. Miyoshi and G.W. Robinson et al., 2003. Selective removal of the selenocysteine tRNA[Ser]Sec gene (Trsp) in mouse mammary epithelium. Mol. Cell. Biol., 23: 1477-1488.
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  35. Kim, S.S., S. Kim, E. Kim, B. Hyun, K.K. Kim and B.J. Lee, 2003. Synergistic inhibitory effect of cationic peptides and antimicrobial agents on the growth of oral streptococci. Caries Res., 37: 425-430.
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  36. Kim, S., S.S. Kim, Y.J. Bang, S.J. Kim and B.J. Lee, 2003. In vitro activities of native and designed peptide antibiotics against drug sensitive and resistant tumor cell lines. Peptides, 24: 945-953.
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  37. Kim, M., J. Choi, B.A. Carlson, J.K. Han and K. Rhee et al., 2003. A novel TBP-interacting zinc finger protein functions in early development of Xenopus laevis. Biochem. Biophys. Res. Commun., 306: 1106-1111.
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  38. Kim, M., C.H. Park, M.S. Lee, B.A. Carlson, D.L. Hatfield and B.J. Lee, 2003. A novel TBP-interacting zinc finger protein represses transcription by inhibiting the recruitment of TFIIA and TFIIB. Biochem. Biophys. Res. Commun., 306: 231-238.
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  39. Kim, H.D., C.Y. Jang, K. Seong, H.C. Sung, J.Y. Lee, B.J. Lee and J. Kim, 2003. Human rpS3 is involved in DNA repair and cell cycle control. J. Photosci., 10: 195-198.
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  40. Chung, J.Y., N.Y. Choi, M.S. Shim, D.W. Choi and H.S. Kang et al., 2003. Construction of deletion map of 16q by LOH analysis from HCC patients and physical map on 16q 23.3-24.1 region. Genom. Inform., 1: 101-107.
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  41. Won, H.S., S.H. Park, H.E. Kim, B. Hyun, M. Kim, B.J. Lee and B.J. Lee, 2002. Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4. Eur. J. Biochem., 269: 4367-4374.
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  42. Lim, Y., S.M. Lee, M. Kim, J.Y. Lee, E.P. Moon, B.J. Lee and J. Kim, 2002. Complete genomic structure of human rpS3: Identification of functional U15bsnoRNA in the fifth intron. Gene, 286: 291-297.
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  43. Jeong, D.W., T.S. Kim, Y.W. Chung, B.J. Lee and I.Y. Kim, 2002. Selenoprotein W is a glutathione-dependent antioxidant in vivo. FEBS Lett., 517: 225-228.
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  44. Park, S., S.H. Park, H.C. Ahn, S. Kim, S.S. Kim, B.J. Lee and B.J. Lee, 2001. Structural study of novel antimicrobial peptides, nigrocins, isolated from Rana nigromaculata. FEBS Lett., 507: 95-100.
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  45. Moustafa, M.E., B.A. Carlson, M.A. El-Saadani, G.V. Kryukov and Q.A. Sun et al., 2001. Selective inhibition of selenocysteine tRNA maturation and selenoprotein synthesis in transgenic mice expressing isopentenyladenosine-deficient selenocysteine tRNA. Mol. Cell. Biol., 21: 3840-3852.
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  46. Martin-Romero, F.J., G.V. Kryukov, A.V. Lobanov, B.A. Carlson, B.J. Lee, V.N. Gladyshev and D.L. Hatfield, 2001. Selenium metabolism in Drosophila: Selenoproteins, selenoprotein mRNA expression, fertility and mortality. J. Biol. Chem., 276: 29798-29804.
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  47. Kwon, J.Y., J. Kim-Ha, B.J. Lee and J. Lee, 2001. The MED-7 transcriptional mediator encoded by let-49 is required for gonad and germ cell development in Caenorhabditis elegans. FEBS Lett., 508: 305-308.
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  48. Carlson, B.A., J.F. Mushinski, D.W. Henderson, S.Y. Kwon, P.F. Crain, B.J. Lee and D.L. Hatfield, 2001. 1-Methylguanosine in place of Y base at position 37 in phenylalanine tRNA is responsible for its shiftiness in retroviral ribosomal frameshifting. Virology, 279: 130-135.
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  49. Carlson, B.A., F.J. Martin-Romero, E. Kumaraswany, M.E. Moustafa, H. Zhi, D.L. Hatfield and B.J. Lee, 2001. Mammalian Selenocysteine tRNA. In: Selenium: Its Molecular Biology and Role in Human Health, Hatfield, D.L. (Ed.). Chapter 3, Kluwer Academic Publishers, Norwell, MA., USA., ISBN-13: 9781461356394, pp: 23-32.
  50. Park, S.H., Y.K. Kim, J.W. Park, B. Lee and B.J. Lee, 2000. Solution structure of the antimicrobial peptide gaegurin 4 by 1H and 15N nuclear magnetic resonance spectroscopy. Eur. J. Biochem., 267: 2695-2704.
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  51. Kwon, S.Y., B.A. Carlson, J.M. Park and B.J. Lee, 2000. Structural organization and expression of the gaegurin 4 gene of Rana rugosa. Biochim. Biophys. Acta (BBA)-Gene Struct. Express., 1492: 185-190.
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  52. Kumaraswamy, E., A. Malykh, K.V. Korotkov, S. Kozyavkin and Y. Hu et al., 2000. Structure-expression relationships of the 15-kDa selenoprotein gene: Possible role of the protein in cancer etiology. J. Biol. Chem., 275: 35540-35547.
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  53. Kim, L.K., T. Matsufuji, S. Matsufuji, B.A. Carlson, S.S. Kim, D.L. Hatfield and B.J. Lee, 2000. Methylation of the ribosyl moiety at position 34 of selenocysteine tRNA[Ser]Sec is governed by both primary and tertiary structure. RNA, 6: 1306-1315.
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  54. Kim, K.W., J.Y. Jhoo, K.U. Lee, D.Y. Lee and J.H. Lee et al., 2000. No association between alpha-1-antichymotrypsin polymorphism and Alzheimer's disease in Koreans. Am. J. Med. Genet., 91: 355-358.
    PubMed  |  
  55. Kim, K.W., J.H. Jhoo, K.U. Lee, D.Y. Lee and J.H. Lee et al., 2000. No association between Presenilin 1 (PS1) intronic polymorphism and sporadic Alzheimer's disease in Koreans. J. Neural Transmission, 107: 1191-1120.
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  56. Carlson, B.A., S.Y. Kwon, B.J. Lee and D. Hatfield, 2000. Yeast asparagine (Asn) tRNA without Q base promotes eukaryotic frameshifting more efficiently than mammalian Asn tRNAs with or without Q base. Mol. Cells, 10: 113-118.
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  57. Baek, H.J., S.Y. Kwon, S. Kim, S.S. Kim and U. Oh et al., 2000. Ligand binding inhibitors of A1 adenosine receptor from Rana rugosa are phospholipase A2s. Eur. J. Biochem., 267: 1340-1346.
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  58. Zhou, X., S.I. Park, M.E. Moustafa, B.A. Carlson and P.F. Crain et al., 1999. Selenium metabolism in Drosophila: Characterization of the selenocysteine tRNA population. J. Biol. Chem., 274: 18729-18734.
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  59. Xu, X.M., X. Zhou, B.A. Carlson, L.K. Kim, T.L. Huh, B.J. Lee and D.L. Hatfield, 1999. The zebrafish genome contains two distinct selenocysteine tRNA[Ser]sec genes. FEBS Lett., 454: 16-20.
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  60. Xu, X.M., B.A. Carlson, L.K. Kim, B.J. Lee, D.L. Hatfield and A.M. Diamond, 1999. Analysis of selenocysteine (Sec) tRNA[Ser]Sec genes in Chinese hamsters. Gene, 239: 49-53.
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  61. Sun, Q.A., Y. Wu, F. Zappacosta, K.T. Jeang, B.J. Lee, D.L. Hatfield and V.N. Gladyshev, 1999. Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases. J. Biol. Chem., 274: 24522-24530.
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  62. Kim, S.H., J.Y. Kim, B.J. Lee and S.J. Kim, 1999. Synthesis and characterization of GGN4 and its tryptophan substituted analogue peptides. J. Biochem. Mol. Biol., 32: 12-19.
  63. Kim, K.W., J.H. Jhoo, K.U. Lee, D.Y. Lee and J.H. Lee et al., 1999. Association between apolipoprotein E polymorphism and Alzheimer's disease in Koreans. Neurosci. Lett., 277: 145-148.
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  64. Kim, H.J., S.K. Han, J.B. Park, P.D. Ryu, H.J. Baek and B.J. Lee, 1999. Gaegurin 4, a peptide antibiotic of frog skin, forms voltage-dependent channels in planar lipid bilayers. J. Pept. Res., 53: 1-7.
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  65. Huh, J.R., J.M. Park, M. Kim, B.A. Carlson, D.L. Hatfield and B.J. Lee, 1999. Recruitment of TBP or TFIIB to a promoter proximal position leads to stimulation of RNA polymerase II transcription without activator proteins both in vivo and in vitro. Biochem. Biophys. Res. Commun., 256: 45-51.
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  66. Hatfield, D., V. Gladyshev, J.M. Park, I.I. Sang and H.S. Chittum et al., 1999. Biosynthesis of Selenocysteine and its Incorporation into Proteins as the 21st Amino Acid. In: Comprehensive Natural Products Chemistry, Volume 4: Amino Acids, Peptides, Porphyrins and Alkaloids, Kelly, J.W. (Ed.). Elsevier Sci. Ltd., New York, USA., ISBN: 0-08-043156-9, pp: 353-380.
  67. Gladyshev, V.N., M. Krause, X.M. Xu, K.V. Korotkov and G.V. Kryukov et al., 1999. Selenocysteine-containing thioredoxin reductase in C. elegans. Biochem. Biophys. Res. Commun., 259: 244-249.
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  68. Gladyshev, V.N., F.J. Martin-Romero, X.M. Xu, E. Kumaraswamy, B.A. Carlson, D.L. Hatfield and B.J. Lee, 1999. Molecular biology of selenium and its role in cancer, AIDS and other human diseases. Recent Res. Dev. Biochem., 1: 145-167.
  69. Carlson, B.A., S.Y. Kwon, M. Chamorro, S. Oroszlan, D.L. Hatfield and B.J. Lee, 1999. Transfer RNA modification status influences retroviral ribosomal frameshifting. Virology, 255: 2-8.
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  70. Cao, Y., H.L. Kang, X. Xu, M. Wang and S.H. Dho et al., 1999. A 12-Mb complete coverage BAC contig map in human chromosome 16p13.1-p11.2. Genome Res., 9: 763-774.
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  71. Moustafa, M.E., M.A. El-Saadani, K.M. Kandeel, D.B. Mansur, B.J. Lee, D.L. Hatfield and A.M. Diamond, 1998. Overproduction of selenocysteine tRNA in Chinese hamster ovary cells following transfection of the mouse tRNA[Ser]Sec gene. RNA, 4: 1436-1443.
    Direct Link  |  
  72. Lee, K.H., S.Y. Hong, J.E. Oh, B.J. Lee and B.S. Choi, 1998. Antimicrobial activity and conformation of gaegurin-6 amide and its analogs. Peptides, 19: 1653-1658.
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  73. Han, S.J., B.J. Lee and H.S. Kang, 1998. Purification and characterization of the nuclear ribonuclease P of Aspergillus nidulans. Eur. J. Biochem., 251: 244-251.
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  74. Chittum, H.S., W.S. Lane, B.A. Carlson, P.P. Roller, F.D.T. Lung, B.J. Lee and D.L. Hatfield, 1998. Rabbit β-globin is extended beyond its UGA stop codon by multiple suppressions and translational reading gaps. Biochemistry, 37: 10866-10870.
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  75. Park, S.J., J.M. Park, B.J. Lee and K.H. Min, 1997. Role of the amino acid residues in the catalysis of catechol 2,3-dioxygenase from Pseudomonas putida SU10 as probed by chemical modification and random mutagenesis. J. Microbiol., 35: 300-308.
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  76. Park, S.I., J.M. Park, H.S. Chittum, E.S. Yang, B.A. Carlson, B.J. Lee and D.L. Hatfield, 1997. Selenocysteine tRNAs as central components of selenoprotein biosynthesis in eukaryotes. Biomed. Environ. Sci., 10: 116-124.
    PubMed  |  
  77. Park, J.M., J.Y. Lee, D.L. Hatfield and B.J. Lee, 1997. Differential mode of TBP utilization in transcription of the tRNA[Ser]Sec gene and TATA-less class III genes. Gene, 196: 99-103.
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  78. Park, J.M., D.L. Hatfield and B.J. Lee, 1997. Cross-competition for TATA-binding protein between TATA boxes of the selenocysteine tRNA[Ser]Sec promoter and RNA polymerase II promoters. Mol. Cells, 7: 72-77.
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  79. Kim, J.Y., J.M. Park and B.J. Lee, 1997. High-level expression and efficient purification of the antimicrobial peptide gaegurin 4 in E. coli. Protein Pept. Lett., 4: 391-396.
  80. Hori, K., D. Hatfield, F. Maldarelli, B.J. Lee and K.A. Clouse, 1997. Selenium supplementation suppresses tumor necrosis factor α-induced human immunodeficiency virus type 1 replication in vitro. AIDS Res. Hum. Retroviruses, 13: 1325-1332.
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  81. Chittum, H.S., K.E. Hill, B.A. Carlson, B.J. Lee, R.F. Burk and D.L. Hatfield, 1997. Replenishment of selenium deficient rats with selenium results in redistribution of the selenocysteine tRNA population in a tissue specific manner. Biochim. Biophys. Acta (BBA)-Mol. Cell Res., 1359: 25-34.
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  82. Chittum, H.S., H.J. Baek, A.M. Diamond, P. Fernandez-Salguero and F. Gonzalez et al., 1997. Selenocysteine tRNA[Ser]Sec levels and selenium-dependent glutathione peroxidase activity in mouse embryonic stem cells heterozygous for a targeted mutation in the tRNA[Ser]Sec gene. Biochemistry, 36: 8634-8639.
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  83. Baek, H.J., H.S. Chittum, E.S. Yang, S.I. Park and J.M. Park et al., 1997. Response of the selenocysteine tRNA population to selenium in mammals and Xenopus oocytes. Nucleic Acids Symp. Ser., 36: 157-158.
  84. Park, J.M., E.S. Yang, D.L. Hatfield and B.J. Lee, 1996. Analysis of the selenocysteine tRNA[SER]SEC gene transcription in vitro using Xenopus oocyte extracts. Biochem. Biophys. Res. Commun., 226: 231-236.
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  85. Lee, Y.C., B.J. Lee, D.S. Hwang and H.S. Kang, 1996. Purification and characterization of mitochondrial ribonuclease P from Aspergillus nidulans. Eur. J. Biochem., 235: 289-296.
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  86. Lee, Y.C., B.J. Lee and H.S. Kang, 1996. The RNA component of mitochondrial ribonuclease P from Aspergillus nidulans. Eur. J. Biochem., 235: 297-303.
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  87. Lee, B.J., S.I. Park, J.M. Park, H.S. Chittum and D.L. Hatfield, 1996. Molecular biology of selenium and its role in human health. Mol. Cells, 6: 509-520.
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  88. Han, H.Y., C.K. Kim, Y.K. Park, J.E. Ka, B.J. Lee and K.H. Min, 1996. Construction of genetically engineered microorganisms for overexpression of xylE gene encoding catechol 2, 3-dioxygenase and the functional stability of the recombinant plasmid pSW3a containing xylE in aquatic environment. J. Microbiol., 34: 341-348.
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  89. Yoon, J.H., B.J. Lee and H.S. Kang, 1995. The Aspergillus uvsH gene encodes a product homologous to yeast RAD18 and Neurospora UVS-2. Mol. Gen. Genet. MGG, 248: 174-181.
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  90. Park, J.M., J.Y. Lee, H.M. Moon and B.J. Lee, 1995. Molecular cloning of cDNAs encoding precursors of frog skin antimicrobial peptides from Rana rugosa. Biochim. Biophys. Acta (BBA)-Gene Struct. Express., 1264: 23-25.
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  91. Park, J.M., I.S. Choi, S.G. Kang, J.Y. Lee, D.L. Hatfield and B.J. Lee, 1995. Upstream promoter elements are sufficient for selenocysteine tRNA[Ser]Sec gene transcription and to determine the transcription start point. Gene, 162: 13-19.
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  92. Ohama, T., J.E. Jung, S.I. Park, K.A. Clouse, B.J. Lee and D. Hatfield, 1995. Identification of new selenocysteine tRNA[Ser]Sec isoacceptors in human cell lines. Biochem. Mol. Biol. Int., 36: 421-427.
    PubMed  |  
  93. Lee, J.Y., J.M. Park and B.J. Lee, 1995. Construction of assay system for the determination of human immunodeficiency virus type 1 ribosomal frameshifting efficiency in yeast cells. Mol. Cells, 5: 342-347.
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  94. Kim, B.C., J.Q. Kim, J.M. Park and B.J. Lee, 1995. Zinc-dependent cytidine deaminase activity associated with the cloned human apolipoprotein B mRNA editing protein. Mol. Cells, 5: 282-286.
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  95. Park, J.M., J.E. Jung and B.J. Lee, 1994. Antimicrobial peptides from the skin of a Korean frog, Rana rugosa. Biochem. Biophys. Res. Commun., 205: 948-954.
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  96. Oh, H.E., J.M. Park and B.J. Lee, 1994. Functional identification of the protein synthesized from a cDNA encoding the putative TATA-binding protein of Xenopus laevis. Mol. Cells, 4: 231-236.
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  97. Kim, Y.J., B.J. Lee and K.H. Min, 1994. Cloning and nucleotide sequence analysis of xylE encoding catechol 2,3-dioxygenase from Pseudomonas putida SU10. Korean J. Microbiol., 32: 471-479.
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  98. Jung, J.E., V. Karoor, M.G. Sandbaken, B.J. Lee and T. Ohama et al., 1994. Utilization of selenocysteyl-tRNA[Ser]Sec and seryl-tRNA[Ser]Sec in protein synthesis. J. Biol. Chem., 269: 29739-29745.
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  99. Kumar, A., H.R. Kim, R.W. Sobol, S.P. Becerra and B.J. Lee et al., 1993. Mapping of nucleic acid binding in proteolytic domains of HIV-1 reverse transcriptase. Biochemistry, 32: 7466-7474.
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  100. Mitchell, A., A.E. Bale, B.J. Lee, D. Hatfield and H. Harley et al., 1992. Regional localization of the selenocysteine tRNA gene (TRSP) on human chromosome 19. Cytogenet. Genome Res., 61: 117-120.
    CrossRef  |  Direct Link  |  
  101. Hatfield, D.L., J.E. Jung, B.J. Lee and I.S. Choi, 1992. Aminoacyl-tRNA (Anticodon): Codon Adaptation in Higher Eucaryotes. In: Transfer RNA in Protein Synthesis, Hatfield, D., B.J. Lee and R.M. Pirtle (Eds.). Chapter 4, CRC Press, Boca Raton, FL., USA., ISBN-13: 9780849356988, pp: 113-124.
  102. Hatfield, D., I.S. Choi, B.J. Lee and J.E. Jung, 1992. Selenocysteine, a New Addition to the Universal Genetic Code. In: Transfer RNA in Protein Synthesis, Hatfield, D., B.J. Lee and R.M. Pirtle (Eds.). Chapter 9, CRC Press, Boca Raton, FL., USA., ISBN-13: 9780849356988, pp: 269-278.
  103. Hatfield, D., B.J. Lee and R.M. Pirtle, 1992. Transfer RNA in Protein Synthesis. CRC Press, Boca Raton, FL., USA., ISBN-13: 9780849356988, Pages: 448.
  104. Sobol, R.W., R.J. Suhadolnik, A. Kumar, B.J. Lee, D.L. Hatfield and S.H. Wilson, 1991. Localization of a polynucleotide binding region in the HIV-1 reverse transcriptase: Implications for primer binding. Biochemistry, 30: 10623-10631.
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  105. Hatfield, D.L., B.J. Lee, N.M. Price and T.C. Stadtman, 1991. Selenocysteyl-tRNA occurs in the diatom Thalassiosira and in the ciliate Tetrahymena. Mol. Microbiol., 5: 1183-1186.
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  106. Hatfield, D., B.J. Lee, L. Hampton and A.M. Diamond, 1991. Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells. Nucleic Acids Res., 19: 939-943.
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  107. Lee, B.J., M. Rajagopalan, Y.S. Kim, K.H. You, K.B. Jacobson and D. Hatfield, 1990. Selenocysteine tRNA[Ser]Sec gene is ubiquitous within the animal kingdom. Mol. Cell. Biol., 10: 1940-1949.
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  108. Hatfield, D.L., D.W. Smith, B.J. Lee, P.J. Worland and S. Oroszlan, 1990. Structure and function of suppressor tRNAs in higher eukaryote. Crit. Rev. Biochem. Mol. Biol., 25: 71-96.
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  109. Hatfield, D., B.J. Lee, D.W.E. Smith and S. Oroszlan, 1990. Role of Nonsense, Frameshift and Missense Suppressor tRNAs in Mammalian Cells. In: Progress in Molecular and Subcellular Biology, Jeanteur, P., Y. Kuchino, W.E.G. Muller and P.L. Paine (Eds.). Springer, Berlin, Germany, ISBN: 978-3-642-75178-3, pp: 115-146.
  110. Diamond, A.M., Y. Montero-Puerner, B.J. Lee and D. Hatfield, 1990. Selenocysteine inserting tRNAs are likely generated by tRNA editing. Nucleic Acids Res., 18: 6727-6727.
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  111. Lee, B.J., S.G. Kang and D. Hatfield, 1989. Transcription of Xenopus selenocysteine tRNASer (formerly designated opal suppressor phosphoserine tRNA) gene is directed by multiple 5'-extragenic regulatory elements. J. Biol. Chem., 264: 9696-9702.
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  112. Lee, B.J., P.J. Worland, J.N. Davis, T.C. Stadtman and D.L. Hatfield, 1989. Identification of a selenocysteyl-tRNASer in mammalian cells that recognizes the nonsense codon, UGA. J. Biol. Chem., 264: 9724-9727.
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  113. Hatfield, D.L., B.J. Lee, Y.X. Feng, J.G. Levin, A. Rein and S. Oroszlan, 1989. Mechanisms of Ribosomal Frameshifting for Synthesis of the Protease in HIV and other Retroviruses and the Possible Use of Hypomodified tRNAs in the Frameshift Event. In: Proteases of Retroviruses, Kostka, V. (Ed.). Walter De Gruyter & Co., New York, USA., ISBN-13: 9780899255170, pp: 25-34.
  114. Hatfield, D., Y.X. Feng, B.J. Lee, A. Rein, J.G. Levin and S. Oroszlan, 1989. Chromatographic analysis of the aminoacyl-tRNAs which are required for translation of codons at and around the ribosomal frameshift sites of HIV, HTLV-1 and BLV. Virology, 173: 736-742.
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  115. McBride, O.W., A. Mitchell, B.J. Lee, G. Mullenbach and D. Hatfield, 1988. Gene for selenium-dependent glutathione peroxidase maps to human chromosomes 3, 21 and X. BioFactors, 1: 285-292.
    PubMed  |  
  116. Lee, B.J., P. de la Pena, J.A. Tobian, M. Zasloff and D. Hatfield, 1987. Unique pathway of expression of an opal suppressor phosphoserine tRNA. Proc. Natl. Acad. Sci. USA., 84: 6384-6388.
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  117. Lee, B.J., D.H. Lee, Y.J. Kim and H.S. Kang, 1986. Construction of a phylogenetic tree from tRNA sequences. Korean J. Microbiol., 24: 400-405.
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  118. Lee, B.J. and H.S. Kang, 1986. Studies on the organization and expression of tRNA genes in Aspergillus nidulans. VI. The molecular structure of tRNAArg gene of A. nidulans. Korean J. Microbiol., 24: 204-210.
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  119. Lee, B.J. and H.S. Kang, 1986. Studies on the organization and expression of tRNA genes in Aspergillus nidulans. V. The molecular structure of tRNAArg in Aspergillus nidulans. Korean J. Microbiol., 24: 79-85.
  120. Kim, Y.J., B.J. Lee and H.S. Kang, 1986. Studies on the organization and expression of tRNA genes in Aspergillus nidulans. IV. The structure of tRNAAsp gene of Aspergillus nidulans. Korean Biochem. J., 19: 117-124.
  121. Kim, Y.J., B.J. Lee and H.S. Kang, 1986. Studies on the organization and expression of tRNA genes in Aspergillus nidulans. III. The structure of tRNAAsp of Aspergillus nidulans. Korean Biochem. J., 19: 112-116.
  122. Lee, Y.E., B.J. Lee and H.S. Kang, 1985. Characterization of plasmids of Zymomonas mobilis and construction of E. coli-Zymomonas shuttle vector. Korean J. Microbiol., 23: 56-63.
  123. Lee, B.J. and H.S. Kang, 1983. Studies on organization and transcription of Aspergillus nidulans tRNA genes. Cloning of A. nidulans total tRNA genes in Escherichia coli. Korean J. Microbiol., 21: 229-237.
  124. Kim, J., B.J. Lee and H.S. Kang, 1983. Studies on the organization and transcription of Aspergillus nidulans tRNA genes separation and characterization of A. nidulans tRNAs on two-dimensional polyacrylamide gel electrophoresis (I). Korean Biochem. J., 16: 296-306.