Dr. Chi Shing William Cho
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Dr. Chi Shing William Cho

Scientific Officer
Department of Clinical Oncology, Cancer Research Unit, Queen Elizabeth Hospital, Hong Kong

Highest Degree
Ph.D. in Chinese Medicine from The Hong Kong Baptist University, Hong Kong

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Biography

Dr. William Cho is currently working as Scientific Officer at The Hong Kong Baptist University, Hong Kong. He has completed his Ph.D. in Biomedical Sciences from same University. His main area of interest focuses on Biomedical Sciences, and Molecular Sciences. His area of expertise includes Cancer, Proteomics, Chinese Medicine, MicroRNA, and Oncology. He is author and co-author of 102 journal papers.

Area of Interest:

Biomedical Sciences
100%
Cancer
62%
Chinese Medicine
90%
MicroRNA
75%
Oncology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
145
Abstracts
0

Selected Publications

  1. Tsang, H.F., A.C.S. Yu, N. Jin, A.K.Y. Yim and W.M.S. Leung et al., 2022. The clinical application of metagenomic next-generation sequencing for detecting pathogens in bronchoalveolar lavage fluid: Case reports and literature review. Expert Rev. Mol. Diagn., 22: 575-582.
    CrossRef  |  Direct Link  |  
  2. Tsang, H.F., A.C.S. Yu, H.T. Wong, W.M.S. Leung and J. Chiou et al., 2022. Whole genome amplicon sequencing and phylogenetic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from lineage B.1.36.27 isolated in Hong Kong. Expert Rev. Mol. Diagn., 22: 119-124.
    CrossRef  |  Direct Link  |  
  3. Song, Z., S. Lian, S. Mak, M.Z.Y. Chow and C. Xu et al., 2022. Deep RNA sequencing revealed fusion junctional heterogeneity may predict crizotinib treatment efficacy in ALK-rearranged NSCLC. J. Thoracic Oncol., 17: 264-276.
    CrossRef  |  Direct Link  |  
  4. Ahmed, I., V. Ma, Y. Liu, M.S. Khan and Z. Liu et al., 2021. Lithium from breast-milk inhibits thyroid iodine uptake and hormone production, which are remedied by maternal iodine supplementation. Bipolar Disord., 23: 615-625.
    CrossRef  |  Direct Link  |  
  5. Javed, Z., F.A. Shah, S. Rajabi, Q. Raza and Z. Iqbal et al., 2020. LncRNAs as potential therapeutic targets in thyroid cancer. Asian Pac. J. Cancer Prev., 21: 281-287.
    CrossRef  |  Direct Link  |  
  6. Cho, W.C.S., K.P. Tse, R.K.C. Ngan, W. Cheuk and V.W.S. Ma et al., 2020. Genomic characterization reveals potential biomarkers in nasopharyngeal carcinoma patients with relapse. Expert Rev. Mol. Diagn., 20: 1149-1159.
    CrossRef  |  Direct Link  |  
  7. Xue, V.W., M.T. Cheung, P.T. Chan, L.L.Y. Luk and V.H. Lee et al., 2019. Non-invasive potential circulating mRNA markers for colorectal adenoma using targeted sequencing. Sci. Rep., Vol. 9. 10.1038/s41598-019-49445-x.
    CrossRef  |  Direct Link  |  
  8. Xue, V.W., S.S.M. Ng, W.W. Leung, B.B.Y. Ma and W.C.S. Cho et al., 2018. The effect of centrifugal force in quantification of colorectal cancer-related mrna in plasma using targeted sequencing. Front. Genet., Vol. 9. 10.3389/fgene.2018.00165.
    CrossRef  |  Direct Link  |  
  9. Hui, T.H., Y.H. Tang, Z. Yan, T.C. Yip and H.W. Fong et al., 2018. Cadherin- and rigidity-dependent growth of lung cancer cells in a partially confined microenvironment. ACS Biomater. Sci. Eng., 4: 446-455.
    CrossRef  |  Direct Link  |  
  10. Zinger, A., W.C. Cho and A. Ben-Yehuda, 2017. Cancer and aging-the inflammatory connection. Aging Dis., 8: 611-627.
    CrossRef  |  Direct Link  |  
  11. Xue, J., J. Yang, M. Luo, W.C. Cho and X. Liu, 2017. MicroRNA-targeted therapeutics for lung cancer treatment. Expert Opin. Drug Discov., 12: 141-157.
    CrossRef  |  Direct Link  |  
  12. Wong, Y.K., H.F. Tsang, V.W. Xue, C.M. Chan and T.C. Au et al., 2017. Applications of digital PCR in precision medicine. Expert Rev. Precis. Med. Drug Dev., 2: 177-186.
    CrossRef  |  Direct Link  |  
  13. Wong, J.H., S.W.S. Cho, T B. Ng, R.F.C. Chi and C. Tam et al., 2017. Apoptosis and anti-cancer drug discovery: The power of medicinal fungi and plants. Curr. Med. Chem., Vol. 24. 10.2174/0929867324666170720165005.
    CrossRef  |  Direct Link  |  
  14. Wang, E., W.C.S. Cho, S.C.C. Wong and S. Liu, 2017. Disease biomarkers for precision medicine: Challenges and future opportunities. Genom. Proteomics Bioinform., 15: 57-58.
    CrossRef  |  Direct Link  |  
  15. Tosi, U., C.S. Marnell, R. Chang, W.C. Cho, R. Ting, U.B. Maachani and M.M. Souweidane, 2017. Advances in molecular imaging of locally delivered targeted therapeutics for central nervous system tumors. Int. J. Mol. Sci., Vol. 18, No. 2. 10.3390/ijms18020351.
    CrossRef  |  Direct Link  |  
  16. Tortorella, L., G. Vizzielli, D. Fusco, W.C. Cho, R. Bernabei, G. Scambia and G. Colloca, 2017. Ovarian cancer management in the oldest old: Improving outcomes and tailoring treatments. Aging Dis., 8: 677-684.
    CrossRef  |  Direct Link  |  
  17. Tong, C.W.S., W.K.K. Wu, H.H.F. Loong, W.C.S. Cho and K.K.W. To, 2017. Drug combination approach to overcome resistance to EGFR tyrosine kinase inhibitors in lung cancer. Cancer Lett., 405: 100-110.
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  18. Pizzamiglio, S., M. de Bortoli, E. Taverna, M. Signore and S. Veneroni et al., 2017. Expression of iron-related proteins differentiate non-cancerous and cancerous breast tumors. Int. J. Mol. Sci., Vol. 18, No. 2. 10.3390/ijms18020410.
    CrossRef  |  Direct Link  |  
  19. Liu, X. and W.C. Cho, 2017. Precision medicine in immune checkpoint blockade therapy for non-small cell lung cancer. Clin. Transl. Med., Vol. 6. 10.1186/s40169-017-0136-7.
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  20. Liu, G., F. Pei, F. Yang, L. Li and A.D. Amin et al., 2017. Role of autophagy and apoptosis in non-small-cell lung cancer. Int. J. Mol. Sci., Vol. 18, No. 2. 10.3390/ijms18020367.
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  21. Kyrochristos, I.D., G.K. Glantzounis, D.E. Ziogas, I. Gizas and D. Schizas et al., 2017. From clinical standards to translating next-generation sequencing research into patient care improvement for hepatobiliary and pancreatic cancers. Int. J. Mol. Sci., Vol. 18. 10.3390/ijms18010180.
    CrossRef  |  Direct Link  |  
  22. Heo, E.J., Y.J. Cho, W.C. Cho, J.E. Hong and H.K. Jeon et al., 2017. Patient-derived xenograft models of epithelial ovarian cancer for preclinical studies. Cancer Res. Treat., 49: 915-926.
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  23. Garcovich, S., G. Colloca, P. Sollena, B. Andrea and L. Balducci et al., 2017. Skin cancer epidemics in the elderly as an emerging issue in geriatric oncology. Aging Dis., 8: 643-661.
    CrossRef  |  Direct Link  |  
  24. Fu, P., F. Chen, Q. Pan, X. Zhao, C. Zhao, W.C.S. Cho and H. Chen, 2017. The different functions and clinical significances of caveolin-1 in human adenocarcinoma and squamous cell carcinoma. OncoTargets Ther., 10: 819-835.
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  25. Deng, S., Q. Zhao, L. Zhen, C. Zhang and C. Liu et al., 2017. Neonatal heart-enriched miR-708 promotes proliferation and stress resistance of cardiomyocytes in rodents. Theranostics, 7: 1953-1965.
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  26. Chow, J.C.H., K.M. Cheung and W.C.S. Cho, 2017. Atezolizumab in non-small cell lung cancer: The era of precision immuno-oncology. Ann. Transl. Med., Vol. 5, No. 12. 10.21037/atm.2017.03.89.
    CrossRef  |  Direct Link  |  
  27. Cho, W.C., 2017. Mass spectrometry-based proteomics in cancer research. Expert Rev. Proteomics, 14: 725-727.
    CrossRef  |  Direct Link  |  
  28. Cheung, K.M., J.C.H. Chow and W.C.S. Cho, 2017. Characterizing advanced or metastatic adenocarcinoma of lung-one step closer? Transl. Cancer Res., 6: S498-S501.
    CrossRef  |  Direct Link  |  
  29. Chen, J., S. Chi, F. Li, J. Yang, W.C. Cho and X. Liu, 2017. Biologics-induced interstitial lung diseases in rheumatic patients: Facts and controversies. Expert Opin. Biol. Ther., 17: 265-283.
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  30. Chan, L.W., F. Wang, F. Meng, L. Wang and S.C.C. Wong et al., 2017. MiR-30 family potentially targeting PI3K-SIAH2 predicted interaction network represents a novel putative theranostic panel in non-small cell lung cancer. Front. Genet., Vol. 8. 10.3389/fgene.2017.00008.
    CrossRef  |  Direct Link  |  
  31. Babashah, S., B. Bakhshinejad, M.T. Birgani, K. Pakravan and W.C. Cho, 2017. Regulation of microRNAs by phytochemicals: A promising strategy for cancer chemoprevention. Curr. Cancer Drug Targets, Vol. 17. 10.2174/1568009617666170623124710.
    CrossRef  |  PubMed  |  Direct Link  |  
  32. Aunan, J.R., W.C. Cho and K. Soreide, 2017. The biology of aging and cancer: A brief overview of shared and divergent molecular hallmarks. Aging Dis., 8: 628-642.
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  33. Agrawal, M. and W.C. Cho, 2017. Molecular diagnostics in the detection of neurodegenerative disorders. Front. Mol. Biosci., Vol. 4. 10.3389/fmolb.2017.00010.
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  34. Zhang, B., S.M. Deng, L.C. Guo, J.J. Dong and Y.B. Zhu et al., 2016. Effect of gemcitabine on the uptake of 18F-fluorodeoxyglucose and 18F-fluorothymidine in lung adenocarcinoma A549 cells and the animal tumor model. J. Cancer Res. Therapeut., 12: 271-276.
    CrossRef  |  Direct Link  |  
  35. Yang, Y., Y. Du, X. Liu and W.C. Cho, 2016. Involvement of non-coding RNAs in the signaling pathways of colorectal cancer. Adv. Exp. Med. Biol., 937: 19-51.
    CrossRef  |  Direct Link  |  
  36. Yang, J., J. Chen, J. Wei, X. Liu and W.C. Cho, 2016. Immune checkpoint blockade as a potential therapeutic target in non-small cell lung cancer. Expert Opin. Biol. Ther., 16: 1209-1223.
    CrossRef  |  Direct Link  |  
  37. Yang, J., J. Chen, J. He, J. Li, J. Shi, W.C. Cho and X. Liu, 2016. Wnt signaling as potential therapeutic target in lung cancer. Expert Opin. Therapeut. Targets, 20: 999-1015.
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  38. Wang, F., F. Meng, L. Wang, S.C. Wong, W. Cho and L.W. Chan, 2016. Associations of mRNA:microRNA for the shared downstream molecules of EGFR and alternative tyrosine kinase receptors in non-small cell lung cancer. Front. Genet., Vol. 7. 10.3389/fgene.2016.00173.
    CrossRef  |  Direct Link  |  
  39. Tafsiri, E., M. Darbouy, M.B. Shadmehr, W.C. Cho and M. Karimipoor, 2016. Abberent expression of oncogenic and tumor-suppressive microRNAs and their target genes in human adenocarcinoma alveolar basal epithelial cells. J. Cancer Res. Therapeut., 12: 395-400.
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  40. Sun, H.L., Y.Q. Pan, B.S. He, Z.L. Nie and K. Lin et al., 2016. Prognostic performance of lymphocyte-to-monocyte ratio in diffuse large B-cell lymphoma: An updated meta-analysis of eleven reports. OncoTargets Ther., 9: 3017-3023.
    CrossRef  |  Direct Link  |  
  41. Song, G., H. Ni, L. Zou, S. Wang, F. Tian, H. Liu and W.C. Cho, 2016. Expression of CD40 is a positive prognostic factor of diffuse large B-cell lymphoma treated with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone). OncoTargets Ther., 9: 3799-3805.
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  42. Singh, D., W.C. Cho and G. Upadhyay, 2016. Drug-induced liver toxicity and prevention by herbal antioxidants: An overview. Front. Physiol., Vol. 6. 10.3389/fphys.2015.00363.
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  43. Sin, T.K., F. Wang, F. Meng, S.C. Wong and W. Cho et al., 2016. Implications of MicroRNAs in the treatment of gefitinib-resistant non-small cell lung cancer. Int. J. Mol. Sci., Vol. 17, No. 2. 10.3390/ijms17020237.
    CrossRef  |  Direct Link  |  
  44. Ni, H., R. Tong, L. Zou, G. Song and W.C. Cho, 2016. MicroRNAs in diffuse large B-cell lymphoma. Oncol. Lett., 11: 1271-1280.
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  45. Meng, F., F. Wang, L. Wang, S.C. Wong, W. Cho and L.W. Chan, 2016. MiR-30a-5p overexpression may overcome EGFR-inhibitor resistance through regulating PI3K/AKT signaling pathway in non-small cell lung cancer cell lines. Front. Genet., Vol. 7. 10.3389/fgene.2016.00197.
    CrossRef  |  PubMed  |  Direct Link  |  
  46. Liu, X., Q. Fu, Y. Du, Y. Yang and W.C. Cho, 2016. MicroRNA as regulators of cancer stem cells and chemoresistance in colorectal cancer. Curr. Cancer Drug Targets, 16: 738-754.
    CrossRef  |  Direct Link  |  
  47. Liu, X., B. He, W.C. Cho, Y. Pan and J. Chen et al., 2016. A systematic review on the association between the Helicobacter pylori vacA i genotype and gastric disease. FEBS Open Bio, 6: 409-417.
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  48. Kim, H.J., A. Yoon, J.Y. Ryu, Y.J. Cho and J.J. Choi et al., 2016. c-MET as a potential therapeutic target in ovarian clear cell carcinoma. Scient. Rep., Vol. 6. 10.1038/srep38502.
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  49. Hou, J., F. Meng, L.W. Chan, W. Cho and S.C. Wong, 2016. Circulating plasma microRNAs as diagnostic markers for NSCLC. Front. Genet., Vol. 7. 10.3389/fgene.2016.00193.
    CrossRef  |  Direct Link  |  
  50. He, B.S., T. Xu, Y.Q. Pan, H.J. Wang and W.C. Cho et al., 2016. Nucleotide excision repair pathway gene polymorphisms are linked to breast cancer risk in a Chinese population. Oncotarget, 7: 84872-84882.
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  51. Fu, Q., Y. Du, C. Yang, D. Zhang and N. Zhang et al., 2016. An oncogenic role of miR-592 in tumorigenesis of human colorectal cancer by targeting Forkhead Box O3A (FoxO3A). Expert Opin. Therapeut. Targets, 20: 771-782.
    CrossRef  |  Direct Link  |  
  52. Fruci, D., W.C.S. Cho, P. Romania, V. Nobili, F. Locatelli and A. Alisi, 2016. Drug transporters and multiple drug resistance in the most common pediatric solid tumors. Curr. Drug Metab., 17: 308-316.
    CrossRef  |  PubMed  |  Direct Link  |  
  53. Zuo, Z., M. Huang, I. Kanfer, M.S. Chow and W.C. Cho, 2015. Herb-drug interactions: Systematic review, mechanisms and therapies. Evid.-Based Complem. Altern. Med., Vol. 2015. .
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  54. Zhu, Y., X. Song, J. Wang, Y. Li and Y. Yang et al., 2015. Placental mesenchymal stem cells of fetal origin deposit epigenetic alterations during long-term culture under serum-free condition. Expert Opin. Biol. Ther., 15: 163-180.
    CrossRef  |  Direct Link  |  
  55. Yu, H.W. and W.C. Cho, 2015. The role of microRNAs in toxicology. Arch. Toxicol., 89: 319-325.
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  56. Yu, H.W. and W.C. Cho, 2015. The emerging role of miRNAs in combined cancer therapy. Expert Opin. Biol. Ther., 15: 923-925.
    CrossRef  |  Direct Link  |  
  57. Yang, W.C., C.L. Chang, C.R. Li, S. Nammi and W. Cho, 2015. Complementary and alternative medicine for diabetes 2014. Evid. Based Compl. Altern. Med., Vol. 2015. 10.1155/2015/685248.
    CrossRef  |  Direct Link  |  
  58. Yang, C., K. Jin, Y. Tong and W.C. Cho, 2015. Therapeutic potential of cancer stem cells. Med. Oncol., Vol. 32. 10.1007/s12032-015-0619-6.
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  59. Wei, J., F. Li, J. Yang, X. Liu and W.C. Cho, 2015. MicroRNAs as regulators of airborne pollution-induced lung inflammation and carcinogenesis. Arch. Toxicol., 89: 677-685.
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  60. Wang, J., Y. Du, X. Liu, W.C. Cho and Y. Yang, 2015. MicroRNAs as regulator of signaling networks in metastatic colon cancer. Biomed. Res. Int., Vol. 2015. 10.1155/2015/823620.
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  61. Wang, F., W.C. Cho, L.W. Chan, S.C. Wong and N.B. Tsui et al., 2015. Gene network exploration of crosstalk between apoptosis and autophagy in chronic myelogenous leukemia. Biomed. Res. Int., Vol. 2015. 10.1155/2015/459840.
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  62. Turchinovich, A., A.G. Tonevitsky, W.C. Cho and B. Burwinkel, 2015. Check and mate to exosomal extracellular miRNA: New lesson from a new approach. Front. Mol. Biosci., Vol. 2. 10.3389/fmolb.2015.00011.
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  63. Maes, E., W.C. Cho and G. Baggerman, 2015. Translating clinical proteomics: The importance of study design. Expert Rev. Proteomics, 12: 217-219.
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  64. Lu, A., C. Xue, Z. Bian and W.C. Cho, 2015. TCM Zheng classification and clinical trials 2014. Evid-Based Complem. Altern. Med., Vol. 2015. 10.1155/2015/538989.
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  65. Lopez Villar, E., X. Wang, L. Madero and W.C. Cho, 2015. Application of oncoproteomics to aberrant signalling networks in changing the treatment paradigm in acute lymphoblastic leukaemia. J. Cell. Mol. Med., 19: 46-52.
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  66. Liu, C.Z., S.F. Zhou, S.B. Guimaraes, W.C. Cho and G.X. Shi, 2015. Acupuncture and oxidative stress. Evid.-Based Complem. Altern. Med., Vol. 2015. .
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  67. Lianos, G.D., A. Mangano, W.C. Cho, G. Dionigi and D.H. Roukos, 2015. Circulating tumor DNA: New horizons for improving cancer treatment. Future Oncol., 11: 545-548.
    PubMed  |  
  68. Lianos, G.D., A. Mangano, W.C. Cho and D.H. Roukos, 2015. From standard to new genome-based therapy of gastric cancer. Expert Rev. Gastroenterol. Hepatol., 9: 1023-1026.
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  69. Li, F., J. He, J. Wei, W.C. Cho and X. Liu, 2015. Diversity of epithelial stem cell types in adult lung. Stem Cells Int., Vol. 2015. 10.1155/2015/728307.
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  70. Ji, X.W., T.Y. Zhou, Y. Lu, M.J. Wei, W. Lu and W.C. Cho, 2015. Breast cancer treatment and sulfotransferase. Expert Opin. Therapeut. Targets, 19: 821-834.
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  71. Han, F., J. He, F. Li, J. Yang, J. Wei, W.C. Cho and X. Liu, 2015. Emerging roles of microRNAs in EGFR-targeted therapies for lung cancer. Biomed. Res. Int., Vol. 2015. 10.1155/2015/672759.
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  72. Gurda, G.T., L. Zhang, Y. Wang, L. Chen and S. Geddes et al., 2015. Utility of five commonly used immunohistochemical markers TTF-1, Napsin A, CK7, CK5/6 and P63 in primary and metastatic adenocarcinoma and squamous cell carcinoma of the lung: A retrospective study of 246 fine needle aspiration cases. Clin. Transl. Med., Vol. 4. .
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  73. Chan, L.W., X. Lin, G. Yung, T. Lui and Y.M. Chiu et al., 2015. Novel structural co-expression analysis linking the NPM1-associated ribosomal biogenesis network to chronic myelogenous leukemia. Scient. Rep., Vol. 5. 10.1038/srep10973.
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  74. Bowman, L.C. and W.C. Cho, 2015. The role of acupuncture and the cancer challenge. Med. Acupuncture, 27: 135-136.
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  75. Yang, M., D.D. Xu, Y. Zhang, X. Liu, R. Hoeven and W.C. Cho, 2014. A systematic review on natural medicines for the prevention and treatment of Alzheimer's disease with meta-analyses of intervention effect of ginkgo. Am. J. Chin. Med., 42: 505-521.
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  76. Xu, Y., Q. Deng, B. He, Y. Pan and R. Li et al., 2014. The diplotype Fas-1377A/-670G as a genetic marker to predict a lower risk of breast cancer in Chinese women. Tumour Biol., 35: 9147-9161.
  77. Xiao, L., T. Xiao, Z.M. Wang, W.C. Cho and Z.Q. Xiao, 2014. Biomarker discovery of nasopharyngeal carcinoma by proteomics. Expert Rev. Proteomics, 11: 215-225.
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  78. Wang, F., S.C. Wong, L.W. Chan, W.C. Cho, S.P. Yip and B.Y. Yung, 2014. Multiple regression analysis of mRNA-miRNA associations in colorectal cancer pathway. Biomed. Res. Int., Vol. 2014. 10.1155/2014/676724.
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  79. Wang, F., L.W. Chan, W. Cho, P. Tang and J. Yu et al., 2014. Novel approach for coexpression analysis of E2F1-3 and MYC target genes in chronic myelogenous leukemia. BioMed. Res. Int., Vol. 2014. 10.1155/2014/439840.
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  80. Wang, F., L.W. Chan, H.K. Law, W.C. Cho and P. Tang et al., 2014. Exploring microRNA-mediated alteration of EGFR signaling pathway in non-small cell lung cancer using an mRNA: miRNA regression model supported by target prediction databases. Genomics, 104: 504-511.
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  81. Tsang, H., C.L. Chan, K. Chen, W.C. Cho and M.S. Lee, 2014. Scientific basis of mind-body interventions. Evid.-Based Complem. Altern. Med., Vol. 2014. 10.1155/2014/706892.
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  82. Song, G., W.C. Cho, L. Gu, B. He, Y. Pan and S. Wang, 2014. Increased CD59 protein expression is associated with the outcome of patients with diffuse large B-cell lymphoma treated with R-CHOP. Med. Oncol., Vol. 31. 10.1007/s12032-014-0056-y.
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  83. Song, G., L. Gu, J. Li, Z. Tang and H. Liu et al., 2014. Serum microRNA expression profiling predict response to R-CHOP treatment in diffuse large B cell lymphoma patients. Ann. Hematol., 93: 1735-1743.
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  84. Song, G., G. Song, H. Ni, L. Gu and H. Liu et al., 2014. Deregulated expression of miR-224 and its target gene: CD59 predicts outcome of diffuse large B-cell lymphoma patients treated with R-CHOP. Curr. Cancer Drug Targets, 14: 659-670.
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  85. Skvortsov, S., P. Debbage, W.C. Cho, P. Lukas and I. Skvortsova, 2014. Putative biomarkers and therapeutic targets associated with radiation resistance. Expert Rev. Proteomics, 11: 207-214.
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  86. Rossi, M., N. Amodio, M.T. Di Martino, P. Tagliaferri, P. Tassone and W.C. Cho, 2014. MicroRNA and multiple myeloma: From laboratory findings to translational therapeutic approaches. Curr. Pharm. Biotechnol., 15: 459-467.
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  87. Reumer, A., E. Maes, I. Mertens, W.C. Cho and B. Landuyt et al., 2014. Colorectal cancer biomarker discovery and validation using LC-MS/MS-based proteomics in blood: Truth or dare? Expert Rev. Proteomics, 11: 449-463.
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  88. Ma, H., C. Liang, G. Wang, S. Jia and Q. Zhao et al., 2014. MicroRNA-mediated cancer metastasis regulation via heterotypic signals in the microenvironment. Curr. Pharm. Biotechnol., 15: 455-458.
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  89. Ma, C., Y. Li, M. Li, G. Deng and X. Wu et al., 2014. MicroRNA-124 negatively regulates TLR signaling in alveolar macrophages in response to mycobacterial infection. Mol. Immunol., 62: 150-158.
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  90. Lopez Villar, E., D. Wu, W.C. Cho, L. Madero and X. Wang, 2014. Proteomics‐based discovery of biomarkers for paediatric acute lymphoblastic leukaemia: Challenges and opportunities. J. Cell. Mol. Med., 18: 1239-1246.
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  91. Long, C., S.B. Wu and W.C. Cho, 2014. Chemical basis of traditional medicines and new potential applications. Evid.-Based Complem. Altern. Med., Vol. 2014. .
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  92. Lo, T.S., K.D. Hammer, M. Zegarra and W.C. Cho, 2014. Methenamine: A forgotten drug for preventing recurrent urinary tract infection in a multidrug resistance era. Expert Rev. Anti-Infect. Ther., 12: 549-554.
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  93. Liu, N., R.X. Cui, Y. Sun, R. Guo and Y.P. Mao et al., 2014. A four-miRNA signature identified from genome-wide serum miRNA profiling predicts survival in patients with nasopharyngeal carcinoma. Int. J. Cancer, 134: 1359-1368.
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  94. Lianos, G.D., K. Vlachos, O. Zoras, C. Katsios, W.C. Cho and D.H. Roukos, 2014. Potential of antibody-drug conjugates and novel therapeutics in breast cancer management. Onco Targets Ther., 7: 491-500.
    CrossRef  |  Direct Link  |  
  95. Li, Y., C. Liang, H. Ma, Q. Zhao and L. Li et al., 2014. miR-221/222 promotes S-phase entry and cellular migration in control of basal-like breast cancer. Molecules, 19: 7122-7137.
    CrossRef  |  Direct Link  |  
  96. Jayaram, S., M.K. Gupta, R.V. Polisetty, W.C. Cho and R. Sirdeshmukh, 2014. Towards developing biomarkers for glioblastoma multiforme: A proteomics view. Expert Rev. Proteomics, 11: 621-639.
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  97. Huang, Y., R. Regazzi and W.C. Cho, 2014. Out of darkness: Long non-coding RNAs come of age. Front. Genet., Vol. 5. .
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  98. Hao, Q. and W.C. Cho, 2014. Battle against cancer: An everlasting saga of p53. Int. J. Mol. Sci., 15: 22109-22127.
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  99. Eddouks, M., D. Chattopadhyay, V. De Feo and W.C. Cho, 2014. Medicinal plants in the prevention and treatment of chronic diseases 2013. Evid.-Based Complem. Altern. Med., Vol. 2014. 10.1155/2014/180981.
    CrossRef  |  Direct Link  |  
  100. Cremona, M., V. Espina, D. Caccia, S. Veneroni and M. Colecchia et al., 2014. Stratification of clear cell renal cell carcinoma by signaling pathway analysis. Expert Rev. Proteomics, 11: 237-249.
    CrossRef  |  Direct Link  |  
  101. Cho, W.C., M.S. Lee, L. Lao and G. Litscher, 2014. Systematic review and meta-analysis in Chinese medicine. Evid.-Based Complem. Altern. Med., Vol. 2014. .
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  102. Cho, W.C., E. Wang, F.M. Marincola, K. Yao, H. Cai, J. Li and X. Li, 2014. TGFβR2 is a major target of miR-93 in nasopharyngeal carcinoma aggressiveness. Mol. Cancer, Vol. 13. .
    Direct Link  |  
  103. Cho, W.C., 2014. Proteomics in translational cancer research: Biomarker discovery for clinical applications. Expert Rev. Proteomics, 11: 131-133.
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  104. Chen, H., H.Y. Lan, D.H. Roukos and W.C. Cho, 2014. Application of microRNAs in diabetes mellitus. J. Endocrinol., 222: R1-R10.
    CrossRef  |  Direct Link  |  
  105. Badr, H.A., D.M. AlSadek, A.A. Darwish, A.I. ElSayed and B.O. Bekmanov et al., 2014. Lectin approaches for glycoproteomics in FDA-approved cancer biomarkers. Expert Rev. Proteomics, 11: 227-236.
    CrossRef  |  Direct Link  |  
  106. Avital, I., A. Stojadinovic, H. Wang, C. Mannion, W.C. Cho, J. Wang and Y.G. Man, 2014. Isolation of stem cells using spheroids from fresh surgical specimen: An analytic mini-review. Cancer Genom. Proteomics, 11: 57-65.
    Direct Link  |  
  107. Zheng, Z., W.C. Cho, L. Xu, J. Wang and D.M. Sze, 2013. Lessons learnt from evidence-based approach of using Chinese herbal medicines in liver cancer. Evidence-Based Complement. Alternative Med. 10.1155/2013/656351.
    CrossRef  |  Direct Link  |  
  108. Yu, H.W.H., D.M.Y. Sze and W.C. Cho, 2013. MicroRNAs involved in anti-tumour immunity. Int. J. Mol. Sci., 14: 5587-5607.
    CrossRef  |  Direct Link  |  
  109. Yang, W.C., S. Nammi, P.B. Jeppesen and W. Cho, 2013. Complementary and alternative medicine for diabetes. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/831068.
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  110. Yang, C., J. Peng, W. Jiang, Y. Zhang and X. Chen et al., 2013. mTOR activation in immature cells of primary nasopharyngeal carcinoma and anti-tumor effect of rapamycin in vitro and in vivo. Cancer Lett., 341: 186-194.
    CrossRef  |  Direct Link  |  
  111. Xu, D.D., H.M. Lam, R. Hoeven, C.B. Xu, A.W. Leung and W.C. Cho, 2013. Photodynamic therapy induced cell death of hormone insensitive prostate cancer PC-3 cells with autophagic characteristics. Photodiagnosis Photodyn. Ther., 10: 278-287.
    CrossRef  |  Direct Link  |  
  112. Wu, N., C. Liu, C. Bai, Y.P. Han, W.C. Cho and Q. Li, 2013. Over-expression of deubiquitinating enzyme USP14 in lung adenocarcinoma promotes proliferation through the accumulation of β-catenin. Int. J. Mol. Sci., 14: 10749-10760.
    CrossRef  |  Direct Link  |  
  113. Wu, K., R.S. Huang, L. House and W.C. Cho, 2013. Next-generation sequencing for lung cancer. Future Oncol., 9: 1323-1336.
    CrossRef  |  Direct Link  |  
  114. Wang, Y., Y. Li, X. Liu and W.C. Cho, 2013. Genetic and epigenetic studies for determining molecular targets of natural product anticancer agents. Curr. Cancer Drug Targets, 13: 506-518.
    Direct Link  |  
  115. Wang, Y., G. Deng, X. Liu and W.C. Cho, 2013. Monoclonal antibodies in lung cancer. Expert Opin. Biol. Ther., 13: 209-226.
    CrossRef  |  Direct Link  |  
  116. Qian, B., S.A. Nag, Y. Su, S. Voruganti, J.J. Qin, R. Zhang and W.C. Cho, 2013. miRNAs in cancer prevention and treatment and as molecular targets for natural product anticancer agents. Curr. Cancer Drug Targets, 13: 519-541.
    Direct Link  |  
  117. Lu, A., A. Bensoussan, J. Liu, Z. Bian and W.C. Cho, 2013. TCM Zheng classification and clinical trials. Evidence-Based Complement. Alternative Med. 10.1155/2013/723659.
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  118. Li, X., H. Xu, C. Xu, M. Lin and X. Song et al., 2013. The Yin-Yang of DNA damage response: Roles in tumorigenesis and cellular senescence. Int. J. Mol. Sci., 14: 2431-2448.
    CrossRef  |  Direct Link  |  
  119. Li, S.G., H.Y. Chen, C.S. Ou-Yang, X.X. Wang, Z.J. Yang, Y. Tong and W.C. Cho, 2013. The efficacy of Chinese herbal medicine as an adjunctive therapy for advanced non-small cell lung cancer: A systematic review and meta-analysis. PLoS One, Vol. 8. 10.1371/journal.pone.0057604.
    CrossRef  |  Direct Link  |  
  120. Jiang, B., J. Mason, A. Jewett, J. Qian and Y. Ding et al., 2013. Cell budding from normal appearing epithelia: A predictor of colorectal cancer metastasis? Int. J. Biol. Sci., 9: 119-133.
    CrossRef  |  Direct Link  |  
  121. Gu, L., G. Song, L. Cheng, Z. Nie and B. He et al., 2013. Inhibition of miR-21 induces biological and behavioral alterations in diffuse large b-cell lymphoma. Acta Haematol., 130: 87-94.
    CrossRef  |  Direct Link  |  
  122. Gu, H., X. Zhan, G. Zhang, L. Yan and W.C. Cho et al., 2013. Mapping the interactome of overexpressed RAF kinase inhibitor protein in a gastric cancer cell line. BMC Cancer, Vol. 13. 10.1186/1471-2407-13-536.
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  123. Delpu, Y., P. Cordelier, W.C. Cho and J. Torrisani, 2013. DNA methylation and cancer diagnosis. Int. J. Mol. Sci., 14: 15029-15058.
    CrossRef  |  Direct Link  |  
  124. Cho, W.C., 2013. Targeting signaling pathways in lung cancer therapy. Expert Opin. Ther. Targets, 17: 107-111.
    CrossRef  |  Direct Link  |  
  125. Cho, W.C., 2013. Emerging techniques in molecular detection of circulating tumor cells. Expert Rev. Mol. Diagnostics, 14: 131-134.
    CrossRef  |  Direct Link  |  
  126. Cho, W.C. and D.H. Roukos, 2013. Trastuzumab emtansine for advanced HER2-positive breast cancer and beyond: Genome landscape-based targets. Expert Rev. Anticancer Ther., 13: 5-8.
    Direct Link  |  
  127. Chen, H.Y., S.G. Li, W.C. Cho and Z.J. Zhang, 2013. The role of acupoint stimulation as an adjunct therapy for lung cancer: A systematic review and meta-analysis. BMC Complementary Alternative Med., Vol. 13. 10.1186/1472-6882-13-362.
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  128. Bazzan, A.J., A.B. Newberg, W.C. Cho and D.A. Monti, 2013. Diet and nutrition in cancer survivorship and palliative care. Evidence-Based Complementary Alternative Med., Vol. 2013. 10.1155/2013/917647.
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  129. Alisi, A., W.C. Cho, F. Locatelli and D. Fruci, 2013. Multidrug resistance and cancer stem cells in neuroblastoma and hepatoblastoma. Int. J. Mol. Sci., 14: 24706-24725.
    CrossRef  |  Direct Link  |  
  130. Zhong, L.L., H.Y. Chen, W.C. Cho, X.M. Meng and Y. Tong, 2012. The efficacy of Chinese herbal medicine as an adjunctive therapy for colorectal cancer: A systematic review and meta-analysis. Complement Ther. Med., 20: 240-252.
    CrossRef  |  Direct Link  |  
  131. Xu, D.D., R. Hoeven, R. Rong and W.C. Cho, 2012. Rhynchophylline protects cultured rat neurons against methamphetamine cytotoxicity. Evid. Based Complement Altern. Med., 10.1155/2012/636091.
    CrossRef  |  Direct Link  |  
  132. Wu, K., L. House, W. Liu and W.C. Cho, 2012. Personalized targeted therapy for lung cancer. Int. J. Mol. Sci., 13: 11471-11496.
    CrossRef  |  Direct Link  |  
  133. Qi, C.F., Y.S. Kim, S. Xiang, Z. Abdullaev and T.A. Torrey, et al., 2012. Characterization of ARF-BP1/HUWE1 interactions with CTCF, MYC, ARF and p53 in MYC-driven B cell neoplasms. Int. J. Mol. Sci., 13: 6204-6219.
    CrossRef  |  Direct Link  |  
  134. Ozdemir, V. and W.C. Cho, 2012. Theranostics: Rethinking postgenomic diagnostics. Expert Rev. Mol. Diagn, 2: 783-785.
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  135. Lopez, E. and W.C. Cho, 2012. Phosphoproteomics and lung cancer research. Int. J. Mol. Sci., 13: 12287-12314.
    CrossRef  |  Direct Link  |  
  136. Liu, N., N.Y. Chen, R.X. Cui, W.F. Li and Y. Li, et al., 2012. Prognostic value of a microRNA signature in nasopharyngeal carcinoma: A microRNA expression analysis. Lancet. Oncol., 13: 633-641.
    CrossRef  |  Direct Link  |  
  137. Ling, C.Q., J.H. Chiu, B. Oh and W.C. Cho, 2012. Natural products for liver diseases: Basic, clinical and translational research. Evidence-Based Complement. Alternative Med. 10.1155/2012/794343.
    CrossRef  |  Direct Link  |  
  138. Li, T. and W.C. Cho, 2012. MicroRNAs: Mechanisms, functions and progress. Genom. Prot. Bioinformat., 10: 237-238.
  139. Jiang, W., J. Peng, Y. Zhang, W.C. Cho and K. Jin, 2012. The implications of cancer stem cells for cancer therapy. Int. J. Mol. Sci., 13: 16636-16657.
    CrossRef  |  Direct Link  |  
  140. Jiang, B., J. Mason, A. Jewett, W.C. Cho and Y. Man, 2012. Tube-like structures with co-expression of D2-40 and CD34: Newly formed vasculatures? Int. J. Biol. Sci., 8: 1206-1216.
    CrossRef  |  Direct Link  |  
  141. He, Y., X. Zhao, W.C. Cho, J. Gao, L. Fan, G. Yang, H. Chen, 2012. Quantum dots-based immunofluorescent imaging of stromal fibroblasts caveolin-1 and light chain 3B expression and identification of their clinical significance in human gastric cancer. Int. J. Mol. Sci., 13: 13764-13780.
    CrossRef  |  Direct Link  |  
  142. He, B., Y. Pan, W.C. Cho, Y. Xu and L. Gu et al., 2012. The association between four genetic variants in microRNAs (rs11614913, rs2910164, rs3746444, rs2292832) and cancer risk: Evidence from published studies. PLoS One, Vol. 7. 10.1371/journal.pone.0049032.
    CrossRef  |  Direct Link  |  
  143. Eddouks, M., D. Chattopadhyay, V. De Feo and W.C. Cho, 2012. Medicinal plants in the prevention and treatment of chronic diseases. Evid. Based Complement. Altern. Med., 10.1155/2012/458274.
    CrossRef  |  Direct Link  |  
  144. Cho, W.C., D.E. Ziogas, C. Katsios and D.H. Roukos, 2012. Emerging personalized oncology: Sequencing and systems strategies. Future Oncol., 8: 637-641.
  145. Cho, W.C., 2012. Tumor diversity: Implementing NGS into clinic. Gastric Breast Cancer, 11: 121-126.
  146. Cho, W.C., 2012. Science and technology: Revealing genome networks for improving health. Gastric Breast Cancer, 11: 58-64.
    CrossRef  |  Direct Link  |  
  147. Cho, W.C., 2012. Personalized medicine through genome science and network biology advances. Gastric Breast Cancer, 11: 216-220.
  148. Cho, W.C., 2012. MicroRNAs as therapeutic targets and their potential applications in cancer therapy. Expert Opin. Ther. Targets, 16: 747-759.
    CrossRef  |  Direct Link  |  
  149. Cho, W.C., 2012. Great potential of microRNAs as predictive and prognostic markers for cancer. Expert Rev. Mol. Diagn., 12: 315-315.
    Direct Link  |  
  150. Cho, W.C., 2012. Exploiting the therapeutic potential of microRNAs in human cancer. Expert Opin.Ther. Targets, 16: 345-350.
    CrossRef  |  Direct Link  |  
  151. Cho, W.C., 2012. The up and down of KRAS testing for personalized colorectal cancer treatment. Gastric Breast Cancer, 11: 29-31.
    CrossRef  |  Direct Link  |  
  152. Chen, X., R. Andersson, W.C. Cho, D. Christiani and R. Coico et al., 2012. The international effort: Building the bridge for Translational Medicine: Report of the 1st International Conference of Translational Medicine (ICTM). Clin. Trans. Med., Vol. 1. 10.1186/2001-1326-1-15.
    CrossRef  |  Direct Link  |  
  153. Chan, L.W., F.F. Wang and W.C. Cho , 2012. Genomic sequence analysis of EGFR regulation by microRNAs in lung cancer. Curr. Top. Me. Chem., 12: 920-926.
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