Dr. Bingbing Dai
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Dr. Bingbing Dai

Researcher
University of Texas MD Anderson Cancer Center, USA

Highest Degree
Ph.D. in Biochemistry and Molecular Biology from Shanghai Jiao Tong University, China

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Area of Interest:

Molecular Sciences
100%
Experimental Cancer Therapeutics
62%
Target Cancer Therapy
90%
Drug Resistance
75%
Pharmacogenomics
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
47
Abstracts
10

Selected Publications

  1. Zhang, P., L. Ying, R. Xu, S. Ge and W. Mei et al., 2010. Tumor-specific, hypoxia-regulated, WW domain-containing oxidoreductase-expressing adenovirus inhibits human non-small cell lung cancer growth in vivo. Hum. Gene Ther, 21: 27-39.
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  2. Meng, J., B. Dai, B. Fang, B.N. Bekele and W.G. Bornmann et al., 2010. Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo. PLoS One., 5: e14124-e14124.
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  3. Dai, B., R.O. Pieper, D.W. Li, M. Liu and K.D. Aldape et al., 2010. FoxM1B regulates NEDD4-1 expression, leading to cellular transformation and full malignant phenotype in immortalized human astrocytes. Cancer Res., 70: 2951-2961.
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  4. Meng, J., H. Peng, B. Dai, W. Guo and L. Wang et al., 2009. High level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886). Cancer Biol. Ther., 8: 2073-2080.
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  5. Li, Q., N. Zhang, Z. Jia, X. Le and B. Dai et al., 2009. Critical role and regulation of transcription factor FoxM1 in human gastric cancer angiogenesis and progression. Cancer Res., 69: 3501-3509.
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  6. Zhang, Y., N. Zhang, B. Dai, M. Liu, K. Xie, R. Sawaya and S. Huang, 2008. FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells. Cancer Res., 68: 8733-8742.
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  7. Li, K., R. Cai, B. Dai, X.Q. Zhang and H.J. Wang et al., 2007. SATB1 regulates SPARC expression in K562 cell line through binding to a specific sequence in the third intron. Biochem. Biophys. Res. Commun., 356: 6-12.
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  8. Dai, B., S.H. Kang, W. Gong, M. Liu, K.D. Aldape, R. Sawaya and S. Huang, 2007. Aberrant FoxM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells. Oncogene, 26: 6212-6219.
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  9. Liu, M., B. Dai, S.H. Kang, K. Ban and F.J. Huang et al., 2006. FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells. Cancer Res., 66: 3593-3602.
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  10. Zhao, Q., N. Chen, W.M. Wang, J. Lu and B. Dai, 2004. Effect of transforming growth factor-beta on activity of connective tissue growth factor gene promoter in mouse NIH/3T3 fibroblasts. Acta Pharmacol. Sin., 25: 485-489.
    PubMed  |