Dr. Jindong Li
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Dr. Jindong Li

Assistant Professor
Department of Pharmacy, Taizhou People’s Hospital, Taizhou, Jiangsu, Chin


Highest Degree
Ph.D. in Clinical Pharmacology from Xuzhou Medical College, China

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Area of Interest:

Biomedical Sciences
100%
Natural Medicine
62%
Pharmacology
90%
Medicinal Chemistry
75%
Bioorganic Reactions
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
47
Abstracts
0

Selected Publications

  1. Ling, Y., J. Li and L. Zhou, 2023. Smoking-related epigenetic modifications are associated with the prognosis and chemotherapeutics of patients with bladder cancer. Int. J. Immunopathol. Pharmacol., Vol. 37. 10.1177/03946320231166774.
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  2. Hu, C., T. Guo, Y. Zou, J. Gao and Y. Gao et al., 2023. Discovery of dual S-RBD/NRP1-targeting peptides: Structure-based virtual screening, synthesis, biological evaluation, and molecular dynamics simulation studies. J. Enzyme Inhib. Med. Chem., Vol. 38. 10.1080/14756366.2023.2212327.
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  3. Yin, S., S. Mei, Z. Li, Z. Xu and Y. Wu et al., 2022. Non-covalent cyclic peptides simultaneously targeting Mpro and NRP1 are highly effective against Omicron BA.2.75. Front. Pharmacol., Vol. 13. 10.3389/fphar.2022.1037993.
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  4. Xu, Z., Y. Zou, X. Gao, M.M. Niu, J. Li, L. Xue and S. Jiang, 2022. Dual-targeting cyclic peptides of receptor-binding domain (RBD) and main protease (Mpro) as potential drug leads for the treatment of SARS-CoV-2 infection. Front. Pharmacol., Vol. 13. 10.3389/fphar.2022.1041331.
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  5. Wang, Y., H. Zhang, J. Li, M.M. Niu, Y. Zhou and Y. Qu, 2022. Discovery of potent and noncovalent KRASG12D inhibitors: Structure-based virtual screening and biological evaluation. Front. Pharmacol., Vol. 13. 10.3389/fphar.2022.1094887.
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  6. Chen, L., N. Wei, Y. Jiang, C. Yuan and L. Xu et al., 2022. Comparative pharmacokinetics of seven bioactive components after oral administration of crude and processed Qixue Shuangbu prescription in chronic heart failure rats by microdialysis combined with UPLC-MS/MS. J. Ethnopharmacol., Vol. 303. 10.1016/j.jep.2022.116035.
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  7. Chen, L., H. Chen, Q. Yang, Y. Jiang and L. Liu et al., 2022. Guizhi fuling capsule inhibits uterine fibroids growth by modulating Med12-mediated Wnt/β-Catenin signaling pathway. J. Ethnopharmacol., Vol. 290. 10.1016/j.jep.2022.115115.
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  8. Zhen, X., L. Jindong, Z. Yang, R. Yashi and G. Wei et al., 2021. Activation of Nrf2 pathway by dimethyl fumarate attenuates renal ischemia-reperfusion injury. Transplant. Proc., 53: 2133-2139.
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  9. Chen, K., J. Qu, H. Chen, J. Wang and H. Hua et al., 2021. Investigating the medicinal potential, material basis and mechanism of Polygoni Orientalis fructus based on multi-technology integrated network pharmacology. Phytomedicine, Vol. 91. 10.1016/j.phymed.2021.153685.
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  10. Yao, H., X. Zhang, N. Zhang, J. Li, Y. Li and Q. Wei, 2020. Wikstromol from Wikstroemia indica induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway. J. Nat. Med., 75: 178-185.
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  11. Yao, H., N. Zhang, W. Zhang, J. Li, H. Hua and Y. Li, 2020. Discovery of polypodiside as a Keap1-dependent Nrf2 activator attenuating oxidative stress and accumulation of extracellular matrix in glomerular mesangial cells under high glucose. Bioorg. Medic. Chem., 10.1016/j.bmc.2020.115833.
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  12. Yao, H., N. Zhang, W. Zhang, J. Li, H. Hua and Y. Li, 2020. Discovery of a coumarin derivative as Nrf2 activator mitigating oxidative stress and fibrosis in mesangial cells under high glucose. Bioorg. Medic. Chem. Lett., 10.1016/j.bmcl.2020.127490.
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