Dr. Dengshun Miao
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Dr. Dengshun Miao

Professor
Nanjing Medical University, Nanjing, Jiangsu, China


Highest Degree
Ph.D. in Human Anatomy from University of Sheffield, United Kingdom

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Area of Interest:

Biomedical Sciences
100%
Human Anatomy
62%
Orthopaedic Surgery
90%
Molecular Biology
75%
Osteoporosis
55%

Research Publications in Numbers

Books
0
Chapters
5
Articles
167
Abstracts
61

Selected Publications

  1. Liu, B., J. Zhang, J. Zhang, X. Ji, R. Wang, A. Gong and D. Miao, 2024. Metformin prevents mandibular bone loss in a mouse model of accelerated aging by correcting dysregulated AMPK-mTOR signaling and osteoclast differentiation. J. Orthop. Transl., 46: 129-142.
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  2. Yang, R., J. Li, J. Zhang, Q. Xue and R. Qin et al., 2023. 17β-estradiol plays the anti-osteoporosis role via a novel ESR1-Keap1-Nrf2 axis-mediated stress response activation and Tmem119 upregulation. Free Radical Biol. Med., 195: 231-244.
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  3. Xie, C., C. Liang, R. Wang, K. Yi and X. Zhou et al., 2023. Resveratrol suppresses lung cancer by targeting cancer stem-like cells and regulating tumor microenvironment. J. Nutr. Biochem., Vol. 112. 10.1016/j.jnutbio.2022.109211.
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  4. Wang, P., C. Yang, J. Lu, Y. Ren, D. Goltzman and D. Miao, 2023. Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway. J. Orthop. Transl., 40: 13-26.
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  5. Li, J., J. Zhang, Q. Xue, B. Liu and R. Qin et al., 2023. Pyrroloquinoline quinone alleviates natural aging-related osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation. Aging Cell, Vol. 22. 10.1111/acel.13912.
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  6. Yang, R., J. Zhang, J. Li, R. Qin and J. Chen et al., 2022. Inhibition of Nrf2 degradation alleviates age-related osteoporosis induced by 1,25-Dihydroxyvitamin D deficiency. Free Radical Biol. Med., 178: 246-261.
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  7. Li, Y., Y. Wei, H. Li, H. Che, D. Miao, C. Ma and Y. Ren, 2022. Exogenous parathyroid hormone alleviates intervertebral disc degeneration through the sonic hedgehog signalling pathway mediated by CREB. Oxid. Med. Cell. Longevity, Vol. 2022. 10.1155/2022/9955677.
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  8. Miao, D. and D. Goltzman, 2021. Probing the scope and mechanisms of calcitriol actions using genetically modified mouse models. JBMR Plus, Vol. 5. 10.1002/jbm4.10434.
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  9. Yu, S., P. Li, B. Li, D. Miao and Q. Deng, 2020. RelA promotes proliferation but inhibits osteogenic and chondrogenic differentiation of mesenchymal stem cells. FEBS Lett., 594: 1368-1378.
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  10. Yang, X., Z. Zhou, Z. Mao, M. Shen, N. Chen and D. Miao, 2020. Role of p53 deficiency in socket healing after tooth extractions. J. Mol. Histol., 51: 55-65.
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  11. Yang, R., J. Chen, J. Zhang, R. Qin and R. Wang et al., 2020. 1,25-dihydroxyvitamin D protects against age-related osteoporosis by a novel VDR-Ezh2-p16 signal axis. Aging Cell, Vol. 19. 10.1111/acel.13095.
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  12. Yan, Y., C. Xiang, Z. Yang, D. Miao and D. Zhang, 2020. Rho kinase inhibition by fasudil attenuates adriamycin-induced chronic heart injury. Cardiovasc. Toxicol., 20: 351-360.
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  13. Sun, H., W. Qiao, M. Cui, C. Yang and R. Wang et al., 2020. The polycomb protein Bmi1 plays a crucial role in the prevention of 1,25(OH)2D deficiency-induced bone loss. J. Bone Mineral Res., 35: 583-595.
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  14. Chen, H., H. Chen, J. Liang, X. Gu and J. Zhou et al., 2020. TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency. Exp. Mol. Med., 52: 130-151.
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  15. Che, H., J. Li, Y. Li, C. Ma and H. Liu et al., 2020. P16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle. eLife, Vol. 9. 10.7554/elife.52570.
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  16. Zhang, H., Y. Gao, Y. Wang, Y. Yan, Z. Yang, D. Miao and D. Zhang, 2019. The effects of parathyroid hormone-related peptide on cardiac angiogenesis, apoptosis, and function in mice with myocardial infarction. J. Cell. Biochem., 120: 14745-14755.
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  17. Yan, Y., D. Miao, Z. Yang and D. Zhang, 2019. Loss of p27kip1 suppresses the myocardial senescence caused by estrogen deficiency. J. Cell. Biochem., 120: 13994-14003.
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  18. Wang, R., X. Xue, Y. Wang, H. Zhao, Y. Zhang, H. Wang and D. Miao, 2019. BMI1 deficiency results in female infertility by activating p16/p19 signaling and increasing oxidative stress. Int. J. Biol. Sci., 15: 870-881.
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  19. Wang, H., Z. Hu, J. Wu, Y. Mei and Q. Zhang et al., 2019. Sirt1 promotes osteogenic differentiation and increases alveolar bone mass via Bmi1 activation in mice. J. Bone Mineral Res., 34: 1169-1181.
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  20. Li, X., X. Zhao, C. Li, S. Liu and F. Yan et al., 2019. Inhibitor of ghrelin receptor reverses gefitinib resistance in lung cancer. Hum. Cell, 32: 360-366.
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  21. He, X., J. Wang, J. Chen, L. Han and X. Lu et al., 2019. lncRNA UCA1 predicts a poor prognosis and regulates cell proliferation and migration by repressing p21 and SPRY1 expression in GC. Mol. Ther. Nucleic Acids, 18: 605-616.
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  22. Geng, Q., H. Gao, R. Yang, K. Guo and D. Miao, 2019. Pyrroloquinoline quinone prevents estrogen deficiency-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence. Int. J. Biol. Sci., 15: 58-68.
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  23. Chen, L., R. Yang, W. Qiao, W. Zhang and J. Chen et al., 2019. 1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of p16/p53-senescence signaling. Aging Cell, Vol. 18. 10.1111/acel.12951.
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  24. Chen, G., Y. Zhang, S. Yu, W. Sun and D. Miao, 2019. Bmi1 overexpression in mesenchymal stem cells exerts antiaging and antiosteoporosis effects by inactivating p16/p19 signaling and inhibiting oxidative stress. Stem Cells, 37: 1200-1211.
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