Dr. Shaoyong  Ke

Dr. Shaoyong Ke

Research Scientist
Hubei Academy of Agricultural Sciences, China

Highest Degree
Ph.D. in Applied Chemistry from East China University of Science & Technology, China

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Area of Interest:

Applied Chemistry
Drug Discovery
Multicomponents Reaction
Organic Chemistry

Selected Publications

  1. Li, S., H. Li, C. Chen, X. Yue, X. Cao and S. Ke, 2013. Novel aroylhydrazine-amide derivatives bearing pyridine core: synthesis, characterisations and selective colorimetric recognition properties. Supramol. Chem., 25: 384-392.
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  2. Ke, S., Z.G. Zhang, T. Long, Y. Liang and Z.W. Yang, 2013. Novel salicylamide derivatives incorporating neonicotinoid pharmacophore: Design, synthesis, characterization and biological evaluation. Med. Chem. Res., 22: 3621-3628.
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  3. Ke, S., Y. Wei, Z. Yang, K. Wang, Y. Liang and L. Shi, 2013. Novel cycloalkylthiophene-imine derivatives bearing benzothiazole scaffold: Synthesis, characterization and antiviral activity evaluation. Bioorg. Med. Chem. Lett., 23: 5131-5134.
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  4. Ke, S., Y. Wei, L. Shi and Yang Q., Z. Yang, 2013. Synthesis of novel steroid derivatives derived from dehydroepiandrosterone as potential anticancer agents. Anticancer Agents Med. Chem., 13: 1291-1298.
    PubMed  |  
  5. Shi, L., R. Hu, Y. Wei, Y. Liang, Z. Yang and S. Ke, 2012. Anthranilic acid-based diamides derivatives incorporating aryl-isoxazoline pharmacophore as potential anticancer agents: Design, synthesis and biological evaluation. Eur. J. Med. Chem., 54: 549-556.
    CrossRef  |  
  6. Li, S., X. Cao, C. Chen and S. Ke, 2012. Novel salicylic acid-oriented thiourea-type receptors as colorimetric chemosensor: Synthesis, characterizations and selective naked-eye recognition properties. Spectrochim. Acta Part A: Mol. Biomol. Spectrosc., 96: 18-23.
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  7. Ke, S., L. Shi, X. Cao, Q. Yang, Y. Liang and Z. Yang, 2012. Heterocycle-functional gramine analogues: Solvent-and catalyst-free synthesis and their inhibition activities against cell proliferation. Eur. J. Med. Chem., 54: 248-254.
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  8. Ke, S., Y.N. Zhang, W. Shu, Z. Zhang and L. Shi et al., 2011. Structural diversity-guided convenient construction of functionalized polysubstituted butenolides and lactam derivatives. C. R. Chim., 14: 1071-1079.
    CrossRef  |  
  9. Ke, S., X. Cao, Y. Liang, K. Wang and Z. Yang, 2011. Synthesis and biological properties of dihydro-oxadiazine-based heterocyclic derivatives. Mini Rev. Med. Chem., 11: 642-657.
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  10. Cao, X., C. Chen, W. Lu and S. Ke, 2011. Chiralβ-arylalkyl-1 H-1, 2, 4-triazoles as demethylase inhibitors: Biological evaluation and its stereoselective interaction with sterol 14α-demethylase from Penicillium digitatum. Pestic. Biochem. Phys., 99: 189-193.
    CrossRef  |  
  11. Ke, S., T.T. Sun, Z.G. Zhang, Y.N. Zhang, Y. Liang, K. Wang and Z. Yang, 2010. Spirodiclofen analogues as potential lipid biosynthesis inhibitors: A convenient synthesis, biological evaluation and structure-activity relationship. Bull. Korean Chem. Soc., 31: 2315-2321.
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  12. Cao, X.F., T.T. Sun and S. Ke, 2010. Progress in the studies on synthesis and biological properties of butenolide and its derivatives. 30 Chin. J. Org. Chem.,: 1113-1125.
  13. Ke, S.Y., X.H. Qian, F.Y. Liu, N. Wang, Q. Yang and Z. Li, 2009. Novel 4 H-1, 3, 4-oxadiazin-5 (6 H)-ones with hydrophobic and long alkyl chains: Design, synthesis and bioactive diversity on inhibition of monoamine oxidase, chitin biosynthesis and tumor cell. Eur. J. Med. Chem., 44: 2113-2121.
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  14. Ke, S., X. Qian, F. Liu, N. Wang, F. Fan, Z. Li and Q. Yang, 2009. Diacylhydrazine derivatives as novel potential chitin biosynthesis inhibitors: Design, synthesis and structure-activity relationship. Eur. J. Med. Chem., 44: 2985-2993.
    CrossRef  |  
  15. Ke, S., F. Liu, N. Wang, Q. Yang and X. Qian, 2009. 1, 3, 4-Oxadiazoline derivatives as novel potential inhibitors targeting chitin biosynthesis: Design, synthesis and biological evaluation. Bioorg. Med. Chem. Lett., 19: 332-335.
    CrossRef  |  
  16. Ke, S., Z. Li and X. Qian, 2008. 1, 3, 4-Oxadiazole-3 (2 H)-carboxamide derivatives as potential novel class of monoamine oxidase (MAO) inhibitors: Synthesis, evaluation and role of urea moiety. Bioorg. Med. Chem., 16: 7565-7572.
    CrossRef  |  
  17. Ke, S.Y. and S.J. Xue, 2006. Synthesis and herbicidal activity of N-(o-fluorophenoxyacetyl) thioureas derivatives and related fused heterocyclic compounds. Arkivoc, 10: 63-68.
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  18. Xue, S., S. Ke, L. Yan, Z. Cai and Y. Wei, 2005. A trifluoromethyl substituted organoimido derivative of the hexametalate cluster: Synthesis, crystal structure and bioactivity of [Mo 6 O 17(NAr) 2] 2−(Ar= o-CF 3 C 6 H 4). J. Inorg. Biochem., 99: 2276-2281.
    CrossRef  |