Dr. Lingling  Zhang
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Dr. Lingling Zhang

Professor
Anhui Medical University, China


Highest Degree
M.D. in Clinical Pharmacology from Anhui Medical University, China

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Area of Interest:

Pharmacology and Toxicology
100%
Immune-Pharmacology
62%
Molecular Pharamcology
90%
Clinical Pharmacology
75%
Anti-Inflammatory
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Zhang, L., P. Li, S. Song, Y. Liu and Q. Wang et al., 2013. Comparative efficacy of TACI-Ig with TNF-alpha inhibitor and methotrexate in DBA/1 mice with collagen-induced arthritis. Eur. J. Pharmacol., 708: 113-123.
    CrossRef  |  
  2. Song, S.S., B. Huang, Q.T. Wang, Y.J. Wu and J.J. Fu et al., 2013. BF02, a recombinant TNFR2 fusion protein, alleviates rats with adjuvant arthritis by regulating T lymphocytes. Acta Pharmacol. Sin., 34: 414-423.
    Direct Link  |  
  3. Liu, D., P. Li, S. Song, Y. Liu and Q. Wang et al., 2012. Pro-apoptotic effect of Epigallo-catechin-3-gallate on B lymphocytes through regulating BAFF/PI3K/Akt/mTOR signaling in rats with collagen-induced arthritis. Eur. J. Pharmacol., 690: 214-225.
    CrossRef  |  
  4. Li, P.P., D.D. Liu, Y.J. Liu, S.S. Song and Q.T. Wang et al., 2012. BAFF/BAFF-R involved in antibodies production of rats with collagen-induced arthritis via PI3K-Akt-mTOR signaling and the regulation of paeoniflorin. J. Ethnopharmacol., 141: 290-300.
    CrossRef  |  
  5. Zhao, W., T. Tong, L. Wang, P.P. Li, Y. Chang, L.L. Zhang and W. Wei, 2011. Chicken type II collagen induced immune tolerance of mesenteric lymph node lymphocytes by enhancing beta2-adrenergic receptor desensitization in rats with collagen-induced arthritis. Int. Immunopharmacol., 11: 12-18.
    CrossRef  |  
  6. Wang, Q.T., Ma Y.K., D.D. Liu, L.L. Zhang and W. Wei, 2011. The roles of B cells and their interactions with fibroblast-like synoviocytes in pathogenesis of rheumatoid arthritis. Int. Arch. Allergy Immunol., 155: 205-211.
    CrossRef  |  PubMed  |  
  7. Wang, Q.T., L.L. Zhang, H.X. Wu and W. Wei, 2011. The expression change of β-arrestins in fibroblast-like synoviocytes from rats with collagen-induced arthritis and the effect of total glucosides of paeony. J. Ethnopharmacol., 133: 511-516.
    CrossRef  |  
  8. Wang, D., Y. Chang, Y. Wu, L. Zhang and S. Yan et al., 2011. Therapeutic effects of TACI‐Ig on rat with adjuvant arthritis. Clin. Exp. Immunol., 163: 225-234.
    CrossRef  |  
  9. Liu, Y., L. Zhang, Y. Wu, T. Tong and W. Zhao et al., 2011. Therapeutic effects of TACI-Ig on collagen-induced arthritis by regulating T and B lymphocytes function in DBA/1 mice. Eur. J. Pharmacol., 654: 304-314.
    CrossRef  |  
  10. Chang, Y., Y. Wu, D. Wang, W. Wei and Q. Qin et al., 2011. Therapeutic effects of TACI-Ig on rats with adjuvant-induced arthritis via attenuating inflammatory responses. Rheumatology, 50: 862-870.
    CrossRef  |  
  11. Zhang, L.L., Y.J. Liu, T. Tong, Y.Q. Wu and W. Wei, 2010. Establish methods and evaluation indexes of collagen-induced arthritis model in DBA/1 mice. Chin. Pharmacol. Bull., 26: 1108-1111.
  12. Zhang, L.L. and W. Wei, 2010. Implication of BAFF / BAFF-R regulating B lymphocyte function through the PI3K/Akt/mTOR signaling pathway in the pathogenesis of rheumatoid arthritis. Chin. Pharmacol. Bull., 26: 847-850.
  13. Tong, T., W. Zhao, Y.Q. Wu, Y. Chang and Q.T. Wang et al., 2010. Chicken type II collagen induced immune balance of main subtype of helper T cells in mesenteric lymph node lymphocytes in rats with collagen-induced arthritis. Inflammation Res., 59: 369-377.
    CrossRef  |  
  14. Wei, W., L.L. Zhang, J.H. Xu, F. Xiao and C.D. Bao et al., 2009. A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis. Arthritis Res. Therapy, 11: R180-R180.
    Direct Link  |  
  15. Zhang, L.L., W. Wei, Q.T. Wang, J.Y. Chen and Y. Chen, 2008. The cross-talk between MEK1/2-ERK1/2 signaling and G protein - couple signaling by synoviocytes in collagen-induced arthritis rats. Chin. Med. J., 121: 2278-2283.
    PubMed  |  
  16. Zhang, L.L., W. Wei, N.P. Wang, Q.T. Wang and J.Y. Chen et al., 2008. Paeoniflorin suppresses inflammatory mediator production and regulates G protein-coupled signaling in fibroblast-like synoviocytes of collagen induced arthritic rats. Inflammation Res., 57: 388-395.
    CrossRef  |  
  17. Zhang, L.L., W. Wei, F. Xiao, J.H. Xu, C.D. Bao, L.Q. Ni and X.F. Li, 2008. Randomized, double -blind, multi -center, controlled clinical trial of chicken type II collagen in rheumatoid arthritis Arthritis Rheum, 59: 905-910.
  18. Wu, H., W. Wei, L. Song, L. Zhang, Y. Chen and X. Hu, 2007. Paeoniflorin induced immune tolerance of mesenteric lymph node lymphocytes via enhancing β 2-adrenergic receptor desensitization in rats with adjuvant arthritis. Int. Immunopharmacol., 7: 662-673.
    CrossRef  |  
  19. Zhang, L.L., W. Wei, S.X. Yan, X.Y. Hu and W.Y. Sun, 2004. Therapeutic effects of glucosides of Cheanomeles speciosa on collagen-induced arthritis in mice. Acta Pharmacol. Sinica, 25: 1495-1501.
    PubMed  |