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2. Zhang, D., Y. Zhang, L. Zheng, Y. Zhan and L. He, 2013. Graphene oxide/poly-L-lysine assembled layer for adhesion and electrochemical impedance detection of leukemia K562 cancer cells. Biosensors Bioelectronics, 42: 112-118.
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3. Zhang, D., Y. Zhang and L. He, 2013. Sensitive voltammetric determination of baicalein at thermally reduced graphene oxide modified glassy carbon electrode. Electroanalysis, 25: 2136-2144.
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4. Zhan, Y., Y. Chen, R. Liu, H. Zhang and Y. Zhang, 2013. Potentiation of paclitaxel activity by curcumin in human breast cancer cell by modulating apoptosis and inhibiting EGFR signaling. Arch. Pharm. Res., 10.1007/s12272-013-0311-3.
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5. Wang, Y., N. Wang, L. Wu, W. Lu and Y. Zhang, 2013. Simultaneous determination of four components in Baige capsule by HPLC: Application to pharmacokinetics and tissue distribution of normal and middle cerebral artery occlusion rats. Biomed. Chromatography, 10.1002/bmc.3067.
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6. Wang, N., Y. Zhang, L. Wu, Y. Wang and Y. Cao et al., 2013. Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition. Neuropharmacology, 79: 282-289.
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7. Wang, N., L. Zheng, Y. Zhan and Y. Zhang, 2013. A novel taspine derivative suppresses human liver tumor growth and invasion in vitro and in vivo. Oncol. Lett., 6: 855-859.
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8. Wang, N., L. Wu, Y. Cao, Y. Wang and Y. Zhang, 2013. The protective activity of imperatorin in cultured neural cells exposed to hypoxia re-oxygenation injury via anti-apoptosis. Fitoterapia, 90: 38-43.
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9. Wang, C., J. Dong, Y. Zhang, F. Wang and H. Gao et al., 2013. Design, synthesis and biological evaluation of biphenyl urea derivatives as novel VEGFR-2 inhibitors. Med. Chem. Commun., 4: 1434-1438.
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10. Pan, X., F. Wang, Y. Zhang, H. Gao, Z. Hu, S. Wang and J. Zhang, 2013. Design, synthesis and biological activities of Nilotinib derivates as antitumor agents. Bioorganic Med. Chem., 21: 2527-2534.
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11. Niu, X., T. Fan, W. Li, H. Huang, Y. Zhang and W. Xing, 2013. Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice. Toxicol. Applied Pharmacol., 267: 256-265.
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12. Luo, W., X. Wang, L. Zheng, Y. Zhan, D. Zhang, J. Zhang and Y. Zhang, 2013. Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway. J. Cell. Mol. Med., 17: 1316-1324.
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13. Li, W., T. Fan, Y. Zhang, T. Fan, P. Zhou, X. Niu and L. He, 2013. Houttuynia cordata Thunb. volatile oil exhibited anti-inflammatory effects in vivo and inhibited nitric oxide and tumor necrosis factor-a production in lps-stimulated mouse peritoneal macrophages in vitro. Phytotherapy Res., 27: 1629-1639.
14. Zheng, L., X. He, W. Ma, B. Dai, Y. Zhan and Y. Zhang, 2012. Ta1722, an anti-angiogenesis inhibitor targeted on VEGFR-2 against human hepatoma. Biomed. Pharmacotherapy, 66: 499-505.
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15. Zhang, Y.M., B.L. Dai, L. Zheng, Y.Z. Zhan and J. Zhang et al., 2012. A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation. Cell Death Dis., Vol. 3. 10.1038/cddis.2012.145.
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16. Zhang, J., Y. Zhang, X. Pan, C. Wang, Z. Hu, S. Wang and L. He, 2012. Facile synthesis and biological evaluation of novel symmetrical biphenyls as antitumor agents. Med. Chem., 8: 145-150.
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17. Zhan, Y., Y. Zhang, C. Liu, J. Zhang and W.W. Smith et al., 2012. A novel taspine derivative, HMQ1611, inhibits breast cancer cell growth via estrogen receptor α and EGF receptor signaling pathways. Cancer Prevention Res., 5: 864-873.
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18. Lu, W., B. Dai, W. Ma and Y. Zhang, 2012. A novel taspine analog, HMQ1611, inhibits growth of non-small cell lung cancer by inhibiting angiogenesis. Oncol. Lett., 4: 1109-1113.
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19. Li, W., T. Fan, Y. Zhang, X. Niu and W. Xing, 2012. Effect of Chelerythrine against endotoxic shock in mice and its modulation of inflammatory mediators in peritoneal macrophages through the modulation of Mitogen-Activated Protein Kinase (MAPK) pathway. Inflammation, 35: 1814-1824.
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20. He, H.Z., N. Wang, J. Zhang, L. Zheng and Y.M. Zhang, 2012. Tas13D inhibits growth of SMMC-7721 cell via suppression VEGF and EGF expression. Asian Pac. J. Cancer Prev., 13: 2009-2014.
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21. He, H., Y. Zhan, Y. Zhang, J. Zhang and L. He, 2012. Synthesis of novel taspine diphenyl derivatives as fluorescence probes and inhibitors of breast cancer cell proliferation. Luminescence, 27: 310-314.
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22. Zhang, Y., Q. Jiang, N. Wang, B. Dai, Y. Chen and L. He, 2011. Effects of taspine on proliferation and apoptosis by regulating caspase-3 expression and the ratio of Bax/Bcl-2 in A431 cells. Phytotherapy Res., 25: 357-364.
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23. Zhang, Y., L. Zheng, J. Zhang, B. Dai, N. Wang, Y. Chen and L. He, 2011. Anti-tumor activity of taspine by modulating EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo. Planta Med., 77: 1774-1781.
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24. Zhang, Y., J. Zhang, B. Dai, N. Wang and L. He, 2011. Anti-proliferative and apoptotic effects of the novel taspine derivative tas41 in the Caco-2 cell line. Environm. Toxicol. Pharmacol., 31: 406-415.
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25. Zhang, J., Y. Zhang, X. Pan, S. Wang and L. He, 2011. Synthesis and cytotoxic evaluation of novel symmetrical taspine derivatives as anticancer agents. Med. Chem., 7: 286-294.
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26. Zhan, Y., Y. Zhang, Y. Chen, N. Wang, L. Zheng and L. He, 2011. Activity of taspine isolated from Radix et Rhizoma Leonticis against estrogen-receptor-positive breast cancer. Fitoterapia, 82: 896-902.
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27. Zhan, Y., M. Sun, Y. Chen and Y. Zhang, 2011. Determination of taspine using HPLC-MS and its effect on EGFR in A431 and HEK293/EGFR cells. Chromatographia, 74: 383-389.
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28. Li, W., P. Zhou, Y. Zhang and L. He, 2011. Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity. J. Ethnopharmacol., 133: 922-927.
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29. Zhou, Y., W. Luo, L. Zheng, M. Li and Y. Zhang, 2010. Construction of recombinant FGFR1 containing full-length gene and its potential application. Plasmid, 64: 60-67.
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30. Zhang, Y., Y. Qu, J. Zhang and X. Wang, 2010. Ardipusilloside I purified from Ardisia pusilla competitively binds VEGFR and induces apoptosis in NCI-H460 cells. Phytomedicine, 17: 519-526.
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31. Zhang, J., Y. Zhang, Y. Shan, N. Li, W. Ma and L. He, 2010. Synthesis and preliminary biological evaluation of novel taspine derivatives as anticancer agents. Eur. J. Med. Chem., 45: 2798-2805.
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32. Zhang, J., Y. Zhang, S. Zhang, S. Wang and L. He, 2010. Discovery of novel taspine derivatives as antiangiogenic agents. Bioorganic Med. Chem. Lett., 20: 718-721.
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33. Wang, S., S. Meng, Y. Zhang, H. Du and L. He, 2010. A new A431/CMC-online-HPLC/MS method for screening anti-EGFR antagonists from Radix Sophorae Flavescentis. J. Chromatography A, 1217: 5246-5252.
34. Wang, S., M. Sun, Y. Zhang, J. Zhang and L. He, 2010. EGFR/cell membrane chromatography-online-high performance liquid chromatography/mass spectrometry method for screening EGFR antagonists from Radix Angelicae Pubescentis. Sci. China-Chem., 53: 2357-2362.
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35. Sun, M., J. Ren, H. Du, Y. Zhang, J. Zhang, S. Wang and L. He, 2010. A combined A431 cell membrane chromatography and online high performance liquid chromatography/mass spectrometry method for screening compounds from total alkaloid of Radix Caulophylli acting on the human EGFR. J. Chromatography B, 878: 2712-2718.
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36. Li, M., S. Wang, Y. Zhang and L. He, 2010. An online coupled cell membrane chromatography with LC/MS method for screening compounds from Aconitum carmichaeli Debx. acting on VEGFR-2. J. Pharm. Biomed. Anal., 53: 1063-1069.
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37. Zhang, Y., L. He, L. Meng, W. Luo and X. Xu, 2008. Suppression of tumor-induced angiogenesis by taspine isolated fromRadix et Rhizoma Leonticis and its mechanism of action in vitro. Cancer Lett., 262: 103-113.
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38. Zhang, Y., L. He, L. Meng and W. Luo, 2008. Taspine isolated from Radix et Rhizoma Leonticis inhibits proliferation and migration of endothelial cells as well as chicken chorioallantoic membrane neovascularisation. Vascular Pharmacol., 48: 129-137.
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39. Zhang, Y., L. He and Y. Zhou, 2008. Taspine isolated from Radix et Rhizoma Leonticis inhibits growth of human umbilical vein endothelial cell (HUVEC) by inducing its apoptosis. Phytomedicine, 15: 112-119.
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