Biography

Dr. Jianyong Li is a Medicinal Chemist by training, received his BSc degree in Pharmacy in 1995 from Lanzhou University, China, his MS degree in Clinic Veterinary Sciences and his PhD degree in Analytical Chemistry from the Graduate School of Chinese Academy of Science, China in 2000 & 2005 respectively. He was Leader of Research and Development Program for Veterinary Chemical Pharmaceutical at Agricultural Science and Technology Innovative Program of CAAS, Vice Head at Key Laboratory of Veterinary Pharmaceutical Development of Agricultural Ministry of China, Key Laboratory of New Animal Drug Project of Gansu Province, Research Centre of New Animal Drug Project of Gansu Province, and the Department of Veterinary Pharmaceutics. His main research focus is on Research and Development of Novel Animal Drug, including Chemistry, Phamacokinetics, Pharmacology, and Toxicology of Pharmaceuticals. He has developed a Novel Drug Additive, Quinocetone, and finished its Residues in Edible Tissues, which has been widely applied in Clinic. He also completed a study in Pigs on the PK and Quantitative Structure-activity Relationship of Pyroline, an active constituent in a Chinese Herb Plant. He is also working on many projects. He was awarded Night China Patents on Preparations and Application of Veterinary Pharmaceuticals. He has completed 46 research projects as principal investigator. He was awarded the Research Medal of the Nation Government in 2009 and 2011 for his work on new Animal Drugs. He is the national middle age and youth prominent contribution specialist and the national selected person of nation hundred, thousand and ten thousand talent project. He leads a Veterinary Chemical Pharmaceutical team which includes one Professor, four Assistant Professors and five Lecturers. He supervises the work of three current Ph.D. students and six current MS students. He published more than 200 scientific papers, of which English language papers were more than twenty.

Area of Interest:

Pharmacology and Toxicology

100%

Novel Drug Discovery

62%

Pharmacokinetics

90%

Pharmaceuticals

75%

Toxicology

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
0

Abstracts
0

Selected Publications

Shen, Y., X. Liu, Y. Yang, J. Li, N. Ma and B. Li, 2015. In vivo and in vitro metabolism of aspirin eugenol ester in dog by liquid chromatography tandem mass spectrometry. Biomed. Chromatogr., 29: 129-137.
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Shi, Y., J. Li, H. Li, Y. Wang, X. Zhang and H. Wang, 2014. Formulation and optimization of diminazene aceturate thermosensitive hydrogel. Lat. Am. J. Pharm., 33: 398-402.
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Liu, X.W., H. Zhang, Y.J. Yang, J.Y. Li, B. Li, X.Z. Zhou and J.Y. Zhang, 2014. Synthesis, antibacterial evaluation and molecular docking study of nitazoxanide analogues. Asia J. Chem., 26: 2921-2926.
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Li, B., X.Z. Zhou, J.Y. Li, Y.J. Yang and J.R. Niu et al., 2014. Determination and pharmacokinetic studies of arecoline in dog plasma by liquid chromatography-tandem mass spectrometry. J. Chromatogr. B, 969: 12-18.
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Kong, X., X. Liu, J. Li and Y. Yang, 2014. Advances in pharmacological research of eugenol. Curr. Opin. Compl. Alternat. Med., 1: 8-11.
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Yang, Y.J., J.Y. Li, X.W. Liu, J.Y. Zhang, Y.R. Liu and B. Li, 2013. A non-biological method for screening active components against influenza virus from traditional chinese medicine by coupling a LC column with oseltamivir molecularly imprinted polymers. Plos One, Vol. 8. .
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Wang, R., J.Y. Li, H.Y. Qi and Y.P. Shi, 2013. Two new tigliane diterpene esters from the flower buds of Daphne genkwa. J. Asian Natural Prod. Res., 15: 502-506.
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Shi, Y., X. Zhang, J. Li, Z. Wang and S. Cheng et al., 2013. Preparation and pharmacokinetics of an injectable thermosensitive hydrogel of diminazene aceturate. J. Drug Del. Sci. Tech., 23: 531-535.
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Li, J., X. Kong, X. Li, Y. Yang and J. Zhang, 2013. Genotoxic evaluation of aspirin eugenol ester using the Ames test and the mouse bone marrow micronucleus assay. Food Chem. Toxicol., 62: 805-809.
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Zhang, J.Y., X.Z. Zhou, B. Li, Y.J. Yang and X.J. Wei et al., 2012. Therapeutic and persistent efficacy of doramectin against nematode in swine infected naturally in China. J. Anim. Vet. Adv., 24: 4684-4688.
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Liu, X.W., J.Y. Li, H. Zhang, Y.J. Yang and J.Y. Zhang, 2012. N-(5-Chloro-1,3-thiazol-2-yl)-2,4-difluorobenzamid. Acta Cryst. Vol. E68. .
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Li, J., Y. Yu, Y. Yang, X. Liu and J. Zhang et al., 2012. Antioxidant activity of aspirin eugenol ester for aging model of mice by D-galactose. J. Anim. Vet. Adv., 11: 4401-4405.
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Li, J., Y. Yu, Y. Yang, X. Liu and J. Zhang et al., 2012. A 15-day oral dose toxicity study of aspirin eugenol ester in Wistar rats. Food Chem. Toxicol., 50: 1980-1985.
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Li, J., Y. Yu, Q. Wang, J. Zhang and Y. Yang et al., 2012. Synthesis of aspirin eugenol ester and its biological activity. Med. Chem. Res., 21: 995-999.
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Yang, Y.J., J.Y. Li, Y.R. Liu, J.Y. Zhang, B. Li and X.P. Cai, 2011. Optimization of polymerization parameters for the sorption of oseltamivir onto molecularly imprinted polymers. Anal. Bioanal. Chem., 400: 3665-3674.
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Liu, X.W., J.Y. Li, Y.J. Yang and J.Y. Zhang, 2011. 4-Allyl-2-methoxyphenyl-2-acetoxybenzoate. Acta Cryst., Vol. E67. .
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Li, J.Y., J.Y. Zhang, X.Z. Zhou, J.S. Li and R.H. Lu, 2007. Synthesis of the possible metabolites of quinocetone in animals. Heterocyclic Commun., 13: 49-56.
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Li, J.Y., J.Y. Zhang, X.Z. Zhou and P. Zhang, 2007. Synthesis of [³H]quinocetone. Heterocyclic Commun., 13: 183-188.
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Li, J., Y. Yang, J. Liu, R. Zhao, F. Yu and R. Lu, 2005. Syntheses of [¹⁴C]quinocetone. J. Radioanal. Nucl. Chem., 265: 17-20.
Li, J., R. Zhao, J. Li and R. Lu, 2005. Quinocetone promoting growth in fat chicklings. J. Indian. Vet., 82: 1149-1151.
Li, J., R. Lu, A. Yang and J. Zhang, 2004. Syntheses of novel fluoroquinolone compounds. Heterocycl.Commun., 10: 447-450.
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Li, J.Y., J.S. Li, Z.Z. Xu and R.H. Lu, 2003. HPLC determination of quinocetone in edible chicken tissues. Toxicolgy, 191: 55-55.