Dr. Mohammad Nasir Uddin
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Dr. Mohammad Nasir Uddin

Assistant Professor
Texas A&M Health Science Center, USA


Highest Degree
Ph.D. in Biochemistry and Molecular Biology from Gifu University, Japan

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Area of Interest:

Molecular Sciences
100%
Biochemistry
62%
Molecular Biology
90%
Biotechnology
75%
Genetics
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
43
Abstracts
0

Selected Publications

  1. Uddin, M.N., S. Allen, R. Jones, D.C. Zawieja and T.J. Kuehl, 2011. Marinobufagenin and angiogenic imbalance are the indicators of cerebral vascular leak syndrome in preeclampsia. J. Investi. Med., 59: 692-730.
    PubMed  |  
  2. Munshi, M.K., M.N. Uddin and S.S. Glaser, 2011. The role of the renin-angiotensin system in liver fibrosis. Exp. Biol. Med., 236: 557-566.
    PubMed  |  
  3. Agunanne, E., D. Horvat, R. Harrison, M.N. Uddin and R. Jones et al., 2011. Marinobufagenin levels in preeclamptic patients: A preliminary report. Am. J. Pernitol., 28: 509-514.
    PubMed  |  
  4. Abi-Ghanem, D., L.R. Berghman, D. Romo, X. Lai and J. Li et al., 2011. A chemifluorescent immunoassay for the determination of marinobufagenin in body fluids. J. Immunoassay Immunochemistry, 32: 31-46.
    PubMed  |  
  5. Uddin, M.N., E. Agunanne, D. Horvat and J.B. Puschett, 2010. Alterations in the Renin-Angiotensin system in a rat model of human preeclampsia. Am. J. Nephrol., 31: 171-177.
    CrossRef  |  Direct Link  |  
  6. Puschett, J.B., E.E. Agunanne and M.N. Uddin, 2010. Emerging role of the bufodienolides in cardiovascular and renal disease. Am. J. Kidney Dis., 56: 359-370.
    PubMed  |  
  7. Nabi, A.N., K.B. Biswas, Y. Arai, M.N. Uddin and T. Nakagawa et al., 2010. Functional characterization of the decoy peptide, [R10P]IFLKRMPSI[19P]. Front Biosci., 2: 1211-1217.
    PubMed  |  
  8. Nabi, A.H.M.N., K.B. Biswas, Y. Arai, M.N. Uddin and T. Nakagawa et al., 2010. Functional characterization of the decoy peptide, R10piflkrmpsi. Front Biosci., 2: 1211-1217.
  9. Agunanne, E.E., M.N. Uddin, D. Horvat and J.B. Puschett, 2010. Contribution of angiogenic factors in a rat model of Pre-eclampsia. Am. J. Nephrol., 32: 332-339.
    CrossRef  |  Direct Link  |  
  10. Agunanne, A., M.N. Uddin, D. Horvat and J.B. Puschett, 2010. An analysis of the role of angiogenic factors in a rat model of preeclampsia. Am. J. Nephrol., 32: 332-339.
  11. Puschett, J.B., E.E. Agunanne and M.N. Uddin, 2010. Marinobufagenin, resibufagenin and preeclampsia. Biochim. Biophys. Acta. Mol. Basis Dis., 10.1016/j.bbadis.2010.02.005.
    CrossRef  |  
  12. Uddin, M.N., L.B. McLean, F.A. Hunter, D. Horvat and J. Severson et al., 2009. Vascular leak in a rat model of preeclampsia. Am. J. Nephrol., 30: 26-33.
    CrossRef  |  Direct Link  |  
  13. Uddin, M.N., E.W. Childs, D. Horvat and J.B. Puschett, 2009. Marinobufagenin enhances endothelial permeability via activation of apoptotic signaling. Am. J. Physiol. Regul. Integr. Comp. Physiol., 296: R1726-R1734.
    CrossRef  |  Direct Link  |  
  14. Uddin, M.N., E. Agunanne, D. Horvat and J. Puschett, 2009. Marinobufagenin causes enhanced permeability in human brain microvascular endothelial cells via apoptotic signaling. J. Am. Soc. Nephrol., 20: 534-535.
  15. Horvat, D., M.N. Uddin, B. Mitchel, J. Severson and J.B. Puschett, 2009. Resibufogenin prevents the manifestations of preeclampsia in an animal model of the syndrome. Hypertension Pregnancy, 10.1080/10641950802629709.
    CrossRef  |  Direct Link  |  
  16. Aggunanne, E., D. Horvat, M.N. Uddin and J.B. Puschett, 2009. The treatment of preeclampsia in a rat model employing digibind. Am. J. Perinatol., 27: 299-305.
    PubMed  |  
  17. Uddin, M.N., D. Horva, S. Glaser, S. Danchuk and B.M. Mitchell et al., 2008. Marinobufagenin inhibits proliferation and migration of cytotrophoblast and CHO cells. Placenta, 29: 266-273.
    PubMed  |  
  18. Uddin, M.N., D. Horva, S. Glaser, B.M. Mitchell and J.B. Puschett, 2008. Examination of the cellular mechanism by which marinobufagenin inhibits cytotrophoblast function. J. Biol. Chem., 283: 17946-17953.
  19. Uddin, M.N., A.H.M.N. Nabi, T. Nakagawa, A. Ichihara, T. Inagami and F. Suzuki, 2008. Non-proteolytic activation of prorenin: Aactivation by (pro)renin receptor and its inhibition by a prorenin prosegment, decoy peptide. Front. Biosci., 13: 745-753.
    PubMed  |  
  20. Sultana, A., A.H.M.N. Nabi, U.M. Nasir, H, Maruyama, K.M. Suzuki, S. Mishima and F. Suzuki, 2008. A dipeptide YY derived from royal jelly proteins inhibit renin activity. Int. J. Mol. Med., 21: 677-681.
    PubMed  |  
  21. Danchuk, S., S. Sukhanov, D. Horvat, M.N. Uddin and J.B. Puschett, 2008. Effects of resibufogenin in experimental hypertension. Am. J. Nephrol., 28: 8-13.
    CrossRef  |  Direct Link  |  
  22. Nabi, A.H.M.N., M.U. Nasir, M.N. Uddin, T. Nakagawa and H. Iwata et al., 2007. Biochemical and enzymatic properties of prorenin: Role of the `handle` peptide of the prosegment sequence in the binding and activation of prorenin molecule in recepto associated prorenin system. Frontiers Biosci., 12: 4810-4817.
  23. Kaneshiro, Y., A. Ichihara, T. Takemitsu, M. Sakoda and A.H.M.N. Nabi et al., 2007. Slowly progressive, angiotensin II- Independent glomerulosclerosis in human (Pro)renin-Receptor-transgenic rats. J. Am. Soc. Nephrol., 18: 1789-1795.
    CrossRef  |  Direct Link  |  
  24. Hayashi, T., O. Urayama, M. Hori, S. Sakamoto and U.M. Nasir et al., 2007. Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes. J. Psychosom. Res., 62: 703-706.
    CrossRef  |  Direct Link  |  
  25. Uddin, M.N., B.A. Shibib, A.U. Mohamad, T. Tazib and R. Ahsan et al., 2006. Changes in physiological properties of soybean oil under various conditions. Bangladesh J. Med. Sci., 12: 28-34.
  26. Uddin, M.N., A.U. Mohamad, H.B. Shozib, T. Tazib and N. Masum et al., 2006. Evaluation of Prostate-specific antigen levels in sera of patients with prostate diseases using Enzyme-linked immunosorbent assay. Bangladesh J. Med. Sci., 12: 98-102.
  27. Nurun Nabi, A.H.M., A. Kageshima, M.N. Uddin, T. Nakagawa, E.Y. Park and F. Suzuki, 2006. Binding properties of rat prorenin and rennin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system. Int. J. Mol. Med., 18: 483-488.
    Direct Link  |  
  28. Mohamad, A.U., M.N. Uddin, B.A. Shibib, T. Tazib and R. Ahsan et al., 2006. Quantitative assesment of serum alpha-fetoprotein among patients with liver diseases using a solid phase enzyme-linked immunosorbent assay. Bangladesh J. Med. Sci., 12: 20-23.
  29. Uddin, M.N., A.U. Mohamad, T. Tazib, R. Ahsan, J. Shafiq, N. Masum and B.A. Shibib, 2005. Diabetes Mellitus and its complications using Glycosylated Hemoglobin (HbA1c) and others related biochemical parameters. Bangladesh J. Med. Sci., 11: 112-115.
  30. Uddin, M.N. and S.A.M. Khairul Bashar, 2005. Studies on plasma prorenin, rennin and angiotensinogen concentrations in Bangladeshi patients with type 2 diabetes. Bangladesh J. Med. Sci., 11: 33-36.
  31. Shibib, B.A., M.N. Uddin, J. Shafiq and A.U. Mohamad, 2005. Effect of Coccinia indica extract on blood glucose, free fatty acid and hepatic phosphofructokinase-1 of both normal and diabetic rats. Bangladesh J. Med. Sci., 11: 106-111.
  32. Nasir, U.M., M.N. Uddin, S. Iwanaga, A.H.M. Nurun Nabi and O. Urayama et al., 2005. Laughter therapy modulates the parameters of renin-angiotensin system in patients with type 2 diabetes. Int. J. Mol. Med., 16: 1077-1681.
    Direct Link  |  
  33. Nabi, A.H.M.N., M.N. Uddin, T. Nakagawa, T. Orihashi, A. Ebihara, Y. Nakamura and F. Suzuki, 2005. Roles of His 9 (P2 subsite) and His13 (P3' subsite) in angiotensinogen for catalytic reaction of renin. Int. J. Mol. Med., 16: 103-107.
  34. Mohamad, A.U., T. Tazib, R. Ahsan, K. Aktar, T. Shirin, B.A. Shibib and M.N. Uddin, 2005. Level of triiodothyronine, thyroxine and thyroid stimulating hormone in sera of patients with thyroidism in Bangladesh. Bangladesh J. Med. Sci., 11: 101-105.
  35. Khatry, N., J. Kundu, S.C. Bacher, M.N. Uddin and J.K. Kundu, 2005. Studies on antinociceptive, anti-inflammatory and diuretic activities of methanol extract of the aerial parts of Clerodendron viscosum Vent. Dhaka Univ. J. Pharm. Sci., 5: 63-66.
  36. Ahsan, R., A.U. Mohamad, T. Tazib, B.A. Shibib, J. Shafiq and M.N. Uddin, 2005. Biochemical parameters related to kidney diseases in Bangladeshi patients. Bangladesh J. Med. Sci., 11: 121-126.
  37. Ichihara, A., M. Hayashi, Y. kaneshiro, F. Suzuki and T. Nakagawa et al., 2004. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the handle region for non-proteolytic activation of prorenin. J. Clin. Invest., 114: 1128-1135.
    CrossRef  |  Direct Link  |  
  38. Suzuki, F., M. Hayakawa, T. Nakagawa, U.M. Nasir and M.N. Uddin et al., 2003. Human prorenin has the regions of gate and handle for its non-proteolytic activation.. Biol. Chem., 278: 22217-22222.
  39. Uddin, M.N. and S.N. Shahed, 2002. Purification and characterization of human renin and sheep angiotensinogen. Bangladesh J. Med. Sci., 8: 84-88.
  40. Rahman, S.M., M.N. Huda, M.N. Uddin and S. Akhtaruzzaman, 2002. Shortterm administration of Conjugated Linoleic acid reduces liver triglyceride concentration and phosphatidate phosphohydrolase activity in OLETF rats. J. Biochem. Mol. Biol., 35: 494-497.
  41. Shahed, S.N. and M.N. Uddin, 2001. Kinetic properties of recombinant human phenyl-ethanolamine-N-methyltransferase produced in Escherichia coli. Bangladesh J. Med. Sci., 7: 79-83.
  42. Ebihara, A., U.M. Nasir, M.N. Uddin, S. Yoshida and T. Kondou et al., 2000. Sialic acid residue of ovine angiotensinogen does not affect the reactivity to human renin. Biomed. Res., 21: 105-109.
  43. Ebihara, A., T. Kondou, S. Mizuno, T. Nakagawa and U.M. Nasir et al., 2000. Molecular properties of recombinant ovine angiotensinogen. Biomed. Res., 21: 247-254.