Dr. Hui  Fen Liao
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Dr. Hui Fen Liao

Professor
National Chiayi University, Taiwan


Highest Degree
Ph.D. in Medicine from National Yang-Ming University, Taipei, Taiwan

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Area of Interest:

Biomedical Sciences
100%
Medicine
62%
Traditional Medicine
90%
Oral Cancer
75%
Chemotherapeutic Agents
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Liu, C.K., C.A. Chen, T.Y. Lee, H.H. Chang, H.F. Liao and Y.J. Chen, 2018. Rice protein prolamin promotes anti-leukemia immunity and inhibits leukemia growth in vivo. Food Chem. Toxicol., 112: 435-440.
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  2. Yu, C.C., S.K. Hung, H.Y. Lin, W.Y. Chiou and M.S. Lee et al., 2017. Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo. Oncotarget, 8: 68641-68653.
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  3. Yu, C.C., H.B. Huang, S.K. Hung, H.F. Liao and C.C. Lee et al., 2016. AZD2014 radiosensitizes oral squamous cell carcinoma by inhibiting AKT/mTOR axis and inducing G1/G2/M cell cycle arrest. PLoS ONE, Vol. 11. 10.1371/journal.pone.0151942.
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  4. Huang, Y.T., H.F. Liao, S.L. Wang and S.Y. Lin, 2016. Glycation and secondary conformational changes of human serum albumin: Study of the FTIR spectroscopic curve-fitting technique. Biophysics, 3: 247-260.
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  5. Chang, M.C., J.Y. Wu, H.F. Liao, Y.J. Chen and C.D. Kuo, 2016. Comparative assessment of therapeutic safety of norcantharidin, N-farnesyloxy-norcantharimide and N-farnesyl-norcantharimide against Jurkat T cells relative to human normal lymphoblast: A quantitative pilot study. Medicine, Vol. 95, No. 31. 10.1097/MD.0000000000004467.
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  6. Liao, H.F., T.J. Wu, J.L. Tai, M.C. Chi and L.L. Lin, 2015. Immunomodulatory potential of the polysaccharide-rich extract from edible cyanobacterium Nostoc commune. Med. Sci., 3: 112-123.
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  7. Chang, M.C., J.Y. Wu, H.F. Liao, Y.J. Chen and C.D. Kuo, 2015. N-Farnesyloxy-norcantharimide inhibits progression of human leukemic Jurkat T cells through regulation of mitogen-activated protein kinase and interleukin-2 production. Anti-Cancer Drugs, 26: 1034-1042.
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  8. Chang, M.C., E.T. Tsai, J.Y. Wu, H.F. Liao, Y.J. Chen and C.D. Kuo, 2015. N-Farnesyloxy-norcantharimide and N-farnesyl-norcantharimide inhibit the progression of leukemia and increase survival days in a syngeneic mouse leukemia model. Anti-Cancer Drugs, 26: 508-517.
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  9. Yu, C.C., S.K. Hung, H.F. Liao, C.C. Lee and H.Y. Lin et al., 2014. RAD001 enhances the radiosensitivity of SCC4 oral cancer cells by inducing cell cycle arrest at the G2/M checkpoint. Anticancer Res., 34: 2927-2935.
    PubMed  |  Direct Link  |  
  10. Wu, J.Y., C.D. Kuo, C.Y. Chu, M.S. Chen, J.H. Lin, Y.J. Chen and H.F. Liao, 2014. Synthesis of novel lipophilic N-substituted norcantharimide derivatives and evaluation of their anticancer activities. Molecules, 19: 6911-6928.
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  11. Lee, T.H., C.C. Chen, J.J. Chen, H.F. Liao and H.S. Chang et al., 2014. New and cytotoxic components from Antrodia camphorata. Molecules, 19: 21378-21385.
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  12. Chen, Y.J., Y.C. Huang, T.H. Tsai and H.F. Liao, 2014. Effect of wasabi component 6-(methylsulfinyl)hexyl isothiocyanate and derivatives on human pancreatic cancer cells. Evidence-Based Complement. Altern. Med. 10.1155/2014/494739.
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  13. Su, Y.C., S.C. Li, Y.C. Wu, L.M. Wang, K.S. Chao and H.F. Liao, 2013. Resveratrol downregulates interleukin-6-stimulated sonic hedgehog signaling in human acute myeloid leukemia. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/547430.
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  14. Su, Y.C., S.C. Li, H.Y. Peng, Y.H. Ho, L.J. Chen and H.F. Liao, 2013. RAD001-mediated STAT3 upregulation and megakaryocytic differentiation. Thrombosis Haemostasis, 109: 540-549.
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  15. Liao, H.F., K.C. Chao, Y.J. Chen and M.S. Chang, 2013. Complementary and alternative medicine in cancer stem cells. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/560274.
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  16. Huang, Y.C., K.S. Chao, H.F. Liao and Y.J. Chen, 2013. Targeting sonic hedgehog signaling by compounds and derivatives from natural products. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/748587.
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  17. Hsieh, C.H., K.S. Chao, H.F. Liao and Y.J. Chen, 2013. Norcantharidin, derivative of cantharidin, for cancer stem cells. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/838651.
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  18. Chen, Y.J., Y.Y. Chen, Y.F. Lin, H.Y. Hu and H.F. Liao, 2013. Resveratrol inhibits alpha-melanocyte-stimulating hormone signaling, viability and invasiveness in melanoma cells. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/632121.
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  19. Su, Y.C., S.C. Li, C.K. Hsu, C.C. Yu, T.J. Lin, C.Y. Lee and H.F. Liao, 2012. G-CSF downregulates natural killer cell-mediated cytotoxicity in donors for hematopoietic SCT. Bone Marrow Transplant., 47: 73-81.
    CrossRef  |  PubMed  |  Direct Link  |  
  20. Liu, C.Y., T.H. Tsai, Y.C. Huang, H.R. Shieh, H.F. Liao and Y.J. Chen, 2012. Differential immunomodulating effects of pegylated liposomal doxorubicin nanoparticles on human macrophages. J. Nanosci. Nanotechnol., 12: 7739-7746.
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  21. Liao, H.F., Y.C. Su, Z.Y. Zheng, C.J. Cai, M.H. Hou, K.C. Chao and Y.J. Chen, 2012. Sonic hedgehog signaling regulates Bcr-Abl expression in human chronic myeloid leukemia cells. Biomed. Pharmacother., 66: 378-383.
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  22. Liao, H.F., C.H. Kao, W.D. Lin, N.W. Hsiao, W.H. Hsu and Y.C. Lee, 2012. N-Acetyl-D-glucosamine 2-epimerase from Anabaena sp. CH1 contains a novel ATP-binding site required for catalytic activity. Process Biochem., 47: 948-952.
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  23. Liao, H.F., A.J. Cheng, H.T. Huang, M.L. Shen, T.K. Hei and Y.J. Chen, 2012. Nuclear factor-κB as a switch in regulation of resveratrol-mediated apoptosis and erythrocytic differentiation in human leukaemia cells. Food Chem., 132: 2094-2101.
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  24. Chiang, M.F., S.T. Yeh, H.F. Liao, N.S. Chang and Y.J. Chen, 2012. Overexpression of WW domain-containing oxidoreductase WOX1 preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. Biomed. Pharmacother., 66: 433-438.
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  25. Chen, Y.Y., C.M. Jiang, S.H. Wang, M.K. Shih, H.Y. Hu and H.F. Liao, 2012. The anti-leukemic lectins from Canavalia ensiformis induce macrophage differentiationthrough cross-regulation between monocytes and lymphocytes. J. Med. Plants Res., 6: 534-543.
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  26. Chen, Y.J., C.D. Kuo, S.H. Chen, W.J. Chen, W.C. Huang, K.C. Chao and H.F. Liao, 2012. Small-molecule synthetic compound norcantharidin reverses multi-drug resistance by regulating Sonic hedgehog signaling in human breast cancer cells. PLoS ONE, Vol. 7. 10.1371/journal.pone.0037006.
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  27. Peng, H.Y. and H.F. Liao, 2011. Staurosporine induces megakaryocytic differentiation through the upregulation of JAK/Stat3 signaling pathway. Ann. Hematol., 90: 1017-1029.
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