1. Lee, H.J., L. Lan, G. Peng, W.C. Chang and M.C. Hsu et al., 2015. Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response. Cell Res., 25: 225-236.
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2. Chen, C.H., Y.P. Lin, J.L. Lin, S.T. Li, C.T. Ren, C.Y. Wu and C.H. Chen, 2015. Rapid identification of terminal sialic acid linkage isomers by Pseudo-MS³ mass spectrometry. Israel J. Chem., 55: 412-422.
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3. Wang, C.Y., C.Y. Wu, T.C. Hung, C.H. Wong and C.H. Chen, 2014. Sequence-constructive SELEX: A new strategy for screening DNA aptamer binding to Globo H. Biochem. Biophys. Res. Commun., 452: 484-489.
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4. Ozdemir, A., J.L. Lin, Y.S. Wang and C.H. Chen, 2014. A deeper look into sonic spray ionization. RSC Adv., 4: 61290-61297.
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5. Lin, T.Y., B.R. Li, S.T. Tsai, C.W. Chen, C.H. Chen, Y.T. Chen and C.Y. Pan, 2014. Improved silicon nanowire field-effect transistors for fast protein-protein interaction screening. Lab Chip, 13: 676-684.
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6. Lee, I.C., T.L. Lo, T.H. Young, Y.C. Li, N.G. Chen, C.H. Chen and Y.C. Chang, 2014. Differentiation of neural stem/progenitor cells using low-intensity ultrasound. Ultrasound Med. Biol., 40: 2195-2206.
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7. Huo, L., C.W. Li, T.H. Huang, Y.C. Lam and W. Xia et al., 2014. Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells. Am. J. Transl. Res., 6: 649-663.
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8. Gillig, K.J. and C.H. Chen, 2014. Increasing the performance of portable ion mobility analyzers: Development of the Periodic Focusing Differential Mobility Analyzer (PFDMA). Mass Spectrom., Vol. 3. 10.5702/massspectrometry.S0032.
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9. Chou, R.H., Y.N. Wang, Y.H. Hsieh, L.Y. Li and W. Xia et al., 2014. EGFR modulates DNA synthesis and repair through tyr phosphorylation of histone H4. Dev. Cell, 30: 224-237.
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10. Zhu, L., N.T. Lin, Z.Y. Xie, S.L. Lee and S.L. Huang et al., 2013. Ruthenium-catalyzed cascade metathetical cyclopolymerization of bisnorbornenes with flexible linkers. Macromolecules, 46: 656-663.
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11. Sudhir, P.R., M.P. Kumari, W.T. Hsu, J. Massiot, C.H. Chen, H.C. Kuo and C.H. Chen, 2013. Quantitative proteomics of protein complexes and their implications for cell reprograming and pluripotency. J. Proteome Res., 12: 5878-5890.
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12. Shen, J., W. Xia, Y.B. Khotskaya, L. Huo and K. Nakanishi et al., 2013. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature, 497: 383-387.
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13. Ozdemir, A., J.L. Lin, K.J. Gillig and C.H. Chen, 2013. Triboelectric spray ionization. J. Mass Spectrom., 48: 154-163.
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14. Ozdemir, A., J.L. Lin, K.J. Gillig and C.H. Chen, 2013. Kelvin spray ionization. Analyst, 138: 6913-6923.
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15. Lai, S.H., K.H. Chang, J.L. Lin, C.L. Wu and C.H. Chen, 2013. Sinapinic acid clusters distribution from monomer to mega Dalton's region in MALDI process. Chem. Phys. Lett., 561: 142-146.
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16. Hung, W.T., S.H. Wang, C.H. Chen, C.H. Chen, J.M. Fang and W.B. Yang, 2013. Tagging N-linked glycan with 2,3-naphthalenediamine for mass spectrometric analysis. J. Chin. Chem. Soc., 60: 955-960.
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17. Huang, T.H., L. Huo, Y.N. Wang, W. Xia and Y. Wei et al., 2013. Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers. Cancer Cell, 23: 796-810.
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18. Hsu, Y.F., J.L. Lin, M.L. Chu, Y.S. Wang and C.H. Chen, 2013. Macromolecular ion accelerator mass spectrometer. Analyst, 138: 7384-7391.
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19. Hsu, Y.F., J.L. Lin, M.L. Chu and C.H. Chen, 2013. Biomolecular dual-ion-trap mass analyzer. Analyst, 138: 4823-4829.
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20. Gillig, K.J. and C.H. Chen, 2013. Critical examination of gas-phase protein conformation/multimer ion formation by electrospray ion mobility-mass spectrometry. Anal. Chem., 85: 2177-2182.
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21. Cheng, L.C., H.M. Chen, T.C. Lai, Y.C. Chan and R.S. Liu et al., 2013. Targeting polymeric fluorescent nanodiamond-gold/silver multi-functional nanoparticles as a light-transforming hyperthermia reagent for cancer cells. Nanoscale, 5: 3931-3940.
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22. Chen, N.G., J.L. Lin, C.Y. Wu, K.J. Gillig and A. Ozdemir, 2013. Novel atmospheric biomolecule ionization technologies. J. Anal. Bioanal. Tech., Vol. S2. 10.4172/2155-9872.S2-003.
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23. Chang, K.C., W.C. Chang, Y. Chang, L.Y. Hung and C.H. Lai et al., 2013. Ran GTPase-activating protein 1 is a therapeutic target in diffuse large B-cell lymphoma. PLoS ONE, Vol. 8. 10.1371/journal.pone.0079863.
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24. Baginskiy, I., T.C. Lai, L.C. Cheng, Y.C. Chan and K.Y. Yang et al., 2013. Chitosan-modified stable colloidal gold nanostars for the photothermolysis of cancer cells. J. Phys. Chem. C, 117: 2396-2410.
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25. Yu, Y.L., R.H. Chou, C.H. Wu, Y.N. Wang and W.J. Chang et al., 2012. Nuclear EGFR suppresses ribonuclease activity of polynucleotide phosphorylase through DNAPK-mediated phosphorylation at serine 776. J. Biol. Chem., 287: 31015-31026.
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26. Wang, Y., Q. Ding, C.J. Yen, W. Xia and J.G. Izzo et al., 2012. The crosstalk of mTOR/S6K1 and Hedgehog pathways. Cancer Cell, 21: 374-387.
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27. Wang, C.Y., T.H. Hsiao, L.H. Chu, Y.L. Lin, J.L. Huang, C.H. Chen and K. Peck, 2012. Unraveling virus identity by detection of depleted probes with capillary electrophoresis. Analytica Chimica Acta, 734: 88-92.
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28. Tsai, S.T., C.C. Tsou, W.Y. Mao, W.C. Chang and H.Y. Han et al., 2012. Label-free quantitative proteomics of CD133-positive liver cancer stem cells. Proteome Sci., Vol. 10. 10.1186/1477-5956-10-69.
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29. Sudhir, P.R., C.H. Chen, M.P. Kumari, M.J. Wang and C.C. Tsou et al., 2012. Label-free quantitative proteomics and N-glycoproteomics analysis of KRAS-activated human bronchial epithelial cells. Mol. Cell. Proteomics, 11: 901-915.
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30. Liu, M., D.F. Lee, C.T. Chen, C.J. Yen and L.Y. Li et al., 2012. IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression. Mol. Cell, 45: 171-184.
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31. Lin, H.C., J.L. Lin, H.H. Lin, S.W. Tsai, A.L. Yu, R.L. Chen and C.H. Chen, 2012. High-speed mass measurement of nanoparticle and virus. Anal. Chem., 84: 4965-4969.
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32. Hsu, Y.F., J.L. Lin, S.H. Lai, M.L. Chu, Y.S. Wang and C.H. Chen, 2012. Macromolecular ion accelerator. Anal. Chem., 84: 5765-5769.
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33. Cheng, L.C., J.H. Huang, H.M. Chen, T.C. Lai and K.Y. Yang et al., 2012. Seedless, silver-induced synthesis of star-shaped gold/silver bimetallic nanoparticles as high efficiency photothermal therapy reagent. J. Mater. Chem., 22: 2244-2253.
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34. Parab, H.J., J.H. Huang, T.C. Lai, Y.H. Jan and R.S. Liu et al., 2011. Biocompatible transferrin-conjugated sodium hexametaphosphate-stabilized gold nanoparticles: Synthesis, characterization, cytotoxicity and cellular uptake. Nanotechnology, Vol. 22, No. 39. 10.1088/0957-4484/22/39/395706.
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35. Lu, I.C., J.L. Lin, S.H. Lai and C.H. Chen, 2011. Frequency-scanning MALDI linear ion trap mass spectrometer for large biomolecular ion detection. Anal. Chem., 83: 8273-8277.
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36. Liu, Y.C., H.Y. Yen, C.Y. Chen, C.H. Chen and P.F. Cheng et al., 2011. Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells. Proc. Natl. Acad. Sci. USA., 108: 11332-11337.
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37. Lin, H.H., Y.C. Li, C.H. Chang, C. Liu, A.L. Yu and C.H. Chen, 2011. Single nuclei Raman spectroscopy for drug evaluation. Anal. Chem., 84: 113-120.
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38. Huang, W.C., Y.J. Chen, L.Y. Li, Y.L. Wei and S.C. Hsu et al., 2011. Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells. J. Biol. Chem., 286: 20558-20568.
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39. Huang, J.H., T.C. Lai, L.C. Cheng, R.S. Liu and C.H. Lee et al., 2011. Modulating cell-uptake behavior of Au-based nanomaterials via quantitative biomolecule modification. J. Mater. Chem., 21: 14821-14829.
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40. Huang, H.P., P.H. Chen, W.L. Hwu, C.Y. Chuang and Y.H. Chien et al., 2011. Human Pompe disease induced pluripotent stem cells for pathogenesis modeling, drug testing and disease marker identification. Hum. Mol. Genet., 20: 4851-4864.
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41. Charkin, O.P., N.M. Klimenko, Y.S. Wang, C.C. Wang, C.H. Chen and S.H. Lin, 2011. Theoretical and experimental study of fullerenol molecules and ions C₆₀(OH)_24-n(OL)_n and C₆₀(OH)_24-n(OL)_nL⁺ successively substituted by alkali metal atoms L (n = 1-24). Russian J. Inorg. Chem., 56: 580-590.
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42. Charkin, O.P., N.M. Klimenko, B.G. Chen, S.H. Lin and C.H. Chen, 2011. Theoretical and experimental study of the structure and stability of multiply Na-substituted glucose and 2,4,6-trihydroxyacetophenone derivatives. Russian J. Inorg. Chem., 56: 61-70.
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43. Chang, Y.L., Y.C. Lee, W.B. Yang and C.H. Chen, 2011. Ionic liquid-assisted electrospray ionization of polysaccharides. J. Mass Spectrom., 46: 367-375.
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44. Chang, Y.L., S.K.S. Liao, Y.C. Chen, W.T. Hung and H.M. Yu et al., 2011. Tagging saccharides for signal enhancement in mass spectrometric analysis. J. Mass Spectrom., 46: 247-255.
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45. Wu, C.I., Y.S. Wang, N.G. Chen, C.Y. Wu and C.H. Chen, 2010. Ultrasound ionization of biomolecules. Rapid Commun. Mass Spectrom., 24: 2569-2574.
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46. Ozdemir, A. and C.H. Chen, 2010. Electrode-assisted desorption electrospray ionization mass spectrometry. J. Mass Spectrom., 45: 1203-1211.
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47. Lu, P.J., P.I. Hsu, C.H. Chen, M. Hsiao and W.C. Chang et al., 2010. Gastric juice acidity in upper gastrointestinal diseases. World J. Gastroenterol., 16: 5496-5501.
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48. Lin, H.C., H.H. Lin, C.Y. Kao, A.L. Yu, W.P. Peng and C.H. Chen, 2010. Quantitative measurement of nano-/microparticle endocytosis by cell mass spectrometry. Angewandte Chemie Int. Edn., 49: 3460-3464.
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49. Lin, C., W.T. Hung, C.H. Chen, J.M. Fang and W.B. Yang, 2010. A new naphthimidazole derivative for saccharide labeling with enhanced sensitivity in mass spectrometry detection. Rapid Commun. Mass Spectrom., 24: 85-94.
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50. Liao, H.Y., C.H. Hsu, S.C. Wang, C.H. Liang and H.Y. Yen et al., 2010. Differential receptor binding affinities of influenza hemagglutinins on glycan arrays. J. Am. Chem. Soc., 132: 14849-14856.
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51. Liang, C.W., Y.T. Lee, C.H. Chen and Y.S. Wang, 2010. Ionizing nonvolatile samples using laser desorption-proton-transfer reaction with cluster reagent ions. Int. J. Mass Spectrom., 291: 61-66.
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52. Huo, L., Y.N. Wang, W. Xia, S.C. Hsu and C.C. Lai et al., 2010. RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus. Proc. Natl. Acad. Sci. USA., 107: 16125-16130.
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53. Hsu, P.I., C.H. Chen, M. Hsiao, D.C. Wu, C.Y. Lin, K.H. Lai and P.J. Lu, 2010. Diagnosis of gastric malignancy using gastric juice α1-antitrypsin. Cancer Epidemiol. Biomarkers Prev., 19: 405-411.
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54. Chen, C.H., J.L. Lin, M.L. Chu and C.H. Chen, 2010. MALDI ion trap mass spectrometer with charge detector for large biomolecule detection. Anal. Chem., 82: 10125-10128.
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55. Chang, W.C., M.S. Huang, C.J. Yang, W.Y. Wang, T.C. Lai, M. Hsiao and C.H. Chen, 2010. Dermcidin identification from exhaled air for lung cancer diagnosis. Eur. Respir. J., 35: 1182-1185.
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56. Chang, W.C., C.K. Chou, C.C. Tsou, S.H. Li and C.H. Chen et al., 2010. Comparative proteomic analysis of proteins involved in the tumorigenic process of seminal vesicle carcinoma in transgenic mice. Int. J. Proteomics. 10.1155/2010/726968.
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57. Ankamwar, B., T.C. Lai, J.H. Huang, R.S. Liu, M. Hsiao, C.H. Chen and Y.K. Hwu, 2010. Biocompatibility of Fe₃O₄ nanoparticles evaluated by in vitro cytotoxicity assays using normal, glia and breast cancer cells. Nanotechnology, Vol. 21, No. 7. 10.1088/0957-4484/21/7/075102.
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58. Yang, J.S., J.L. Yan, C.K. Lin, C.Y. Chen, Z.Y. Xie and C.H. Chen, 2009. Pentiptycene-derived oligo(p-phenyleneethynylene)s: Conformational control, chain-length effects, localization of excitation and intrachain resonance energy transfer. Angewandte Chemie, 121: 10120-10123.
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59. Wang, D.Y., T.S. Teng, Y.C. Wu, Y.C. Lee and K.H. Chen et al., 2009. Silver-nanoparticle-conjugated polypeptide brushes for surface-enhanced raman scattering. J. Phys. Chem. C, 113: 13498-13504.
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60. Parab, H.J., H.M. Chen, T.C. Lai, J.H. Huang and P.H. Chen et al., 2009. Biosensing, cytotoxicity and cellular uptake studies of surface-modified gold nanorods. J. Phys. Chem. C, 113: 7574-7578.
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61. Liang, C.H., C.C. Wang, Y.C. Lin, C.H. Chen, C.H. Wong and C.Y. Wu, 2009. Iron oxide/gold core/shell nanoparticles for ultrasensitive detection of carbohydrate-protein interactions. Anal. Chem., 81: 7750-7756.
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62. Hwang-Verslues, W.W., W.H. Kuo, P.H. Chang, C.C. Pan and H.H. Wang et al., 2009. Multiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markers. PLoS ONE, Vol. 4. 10.1371/journal.pone.0008377.
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63. Hsiao, C.R. and C.H. Chen, 2009. Characterization of DNA chips by nanogold staining. Anal. Biochem., 389: 118-123.
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64. Tseng, S.Y., C.C. Wang, C.W. Lin, C.L. Chen and W.Y. Yu et al., 2008. Glycan arrays on aluminum-coated glass slides. Chem.-Asian J., 3: 1395-1405.
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65. Tsai, S.T., C.H. Chen, Y.T. Lee and Y.S. Wang, 2008. Desorption dynamics of neutral molecules in matrix-assisted laser desorption/ionization. Mol. Phys., 106: 239-247.
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66. Susanto, J., Y.H. Lin, Y.N. Chen, C.R. Shen and Y.T. Yan et al., 2008. Porphyrin homeostasis maintained by ABCG2 regulates self-renewal of embryonic stem cells. PLoS ONE, Vol. 3. 10.1371/journal.pone.0004023.
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67. Peng, W.P., H.C. Lin, M.L. Chu, H.C. Chang, H.H. Lin, A.L. Yu and C.H. Chen, 2008. Charge monitoring cell mass spectrometry. Anal. Chem., 80: 2524-2530.
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68. Nie, Z., F. Cui, M. Chu, C.H. Chen, H.C. Chang and Y. Cai, 2008. Calibration of a frequency-scan quadrupole ion trap mass spectrometer for microparticle mass analysis. Int. J. Mass Spectrom., 270: 8-15.
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69. Jhan, J.W., W.T. Chang, H.C. Chen, M.F. Wu, Y.T. Lee, C.H. Chen and I. Liau, 2008. Integrated multiple multi-photon imaging and Raman spectroscopy for characterizing structure-constituent correlation of tissues. Opt. Express, 16: 16431-16441.
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70. Jessome, L., N.Y. Hsu, Y.S. Wang and C.H. Chen, 2008. Matrix-assisted laser desorption/ionization mechanism study with dihydroxybenzoic acid isomers as matrices. Rapid Commun. Mass Spectrom., 22: 130-134.
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71. Hung, W.T., S.H. Wang, C.H. Chen and W.B. Yang, 2008. Structure determination of β-glucans from Ganoderma lucidum with Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometry. Molecules, 13: 1538-1550.
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72. Huang, J.H., H.J. Parab, R.S. Liu, T.C. Lai and M. Hsiao et al., 2008. Investigation of the growth mechanism of iron oxide nanoparticles via a seed-mediated method and its cytotoxicity studies. J. Phys. Chem. C, 112: 15684-15690.
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73. Hsu, N.Y., S.Y. Tseng, C.Y. Wu, C.T. Ren, Y.C. Lee, C.H. Wong and C.H. Chen, 2008. Desorption ionization of biomolecules on metals. Anal. Chem., 80: 5203-5210.
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74. Chen, C.H., 2008. Review of a current role of mass spectrometry for proteome research. Analytica Chimica Acta, 624: 16-36.
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75. Chang, W.C., P.I. Hsu, Y.Y. Chen, M. Hsiao, P.J. Lu and C.H. Chen, 2008. Observation of peptide differences between cancer and control in gastric juice. Proteomics-Clin. Applic., 2: 55-62.
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76. Peng, W.P., H.C. Lin, H.H. Lin, M. Chu and A.L. Yu et al., 2007. Charge-monitoring laser-induced acoustic desorption mass spectrometry for cell and microparticle mass distribution measurement. Angewandte Chemie Int. Edn., 46: 3865-3869.
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77. Nie, Z., F. Cui, Y.K. Tzeng, H.C. Chang and M. Chu et al., 2007. High-speed mass analysis of whole erythrocytes by charge-detection quadrupole ion trap mass spectrometry. Anal. Chem., 79: 7401-7407.
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78. Lin, N.T., S.Y. Lin, S.L. Lee, C.H. Chen and C.H. Hsu et al., 2007. From polynorbornene to the complementary polynorbornene by replication. Angewandte Chemie Int. Edn., 46: 4481-4485.
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79. Li, M.H., S.T. Tsai, C.H. Chen, C.W. Chen, Y.T. Lee and Y.S. Wang, 2007. Bipolar ion detector based on sequential conversion reactions. Anal. Chem., 79: 1277-1282.
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80. Hsu, P.I., C.H. Chen, C.S. Hsieh, W.C. Chang and K.H. Lai et al., 2007. α1-antitrypsin precursor in gastric juice is a novel biomarker for gastric cancer and ulcer. Clin. Cancer Res., 13: 876-883.
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81. Hsu, N.Y., W.B. Yang, C.H. Wong, Y.C. Lee, R.T. Lee, Y.S. Wang and C.H. Chen, 2007. Matrix‐assisted laser desorption/ionization mass spectrometry of polysaccharides with 2',4',6'-trihydroxyacetophenone as matrix. Rapid Commun. Mass Spectrom., 21: 2137-2146.
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82. Chang, W.C., L.C.L. Huang, Y.S. Wang, W.P. Peng and H.C. Chang et al., 2007. Matrix-Assisted Laser Desorption/Ionization (MALDI) mechanism revisited. Analytica Chimica Acta, 582: 1-9.
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83. Tsai, S.T., C.W. Chen, L.C.L. Huang, M.C. Huang, C.H. Chen and Y.S. Wang, 2006. Simultaneous mass analysis of positive and negative ions using a dual-polarity time-of-flight mass spectrometer. Anal. Chem., 78: 7729-7734.
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84. Peng, W.P., Y.C. Yang, M.W. Kang, Y.K. Tzeng and Z. Nie et al., 2006. Laser-induced acoustic desorption mass spectrometry of single bioparticles. Angewandte Chemie, 118: 1451-1454.
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85. Chen, C.H., 2005. Mass Spectrometry, High Speed DNA Fragment Sizing. In: Encyclopedia of Molecular Cell Biology and Molecular Medicine, Volume 7, Meyers, R.A. (Ed.). 2nd Edn., Wiley-VCH Verlag GmbH & Co., Weinheim, Germany, ISBN-13: 978-3527305490, pp: 589-619.
86. Zhu, J.H., C.T. Liu and C.H. Chen, 2004. Effect of iron additions on environmental embrittlement of NiTi-base alloys. Intermetallics, 12: 859-868.
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87. Qiu, X.Y., R.A. Hurt, L.Y. Wu, C.H. Chen, J.M. Tiedje and J.Z. Zhou, 2004. Detection and quantification of copper-denitrifying bacteria by quantitative competitive PCR. J. Microbiol. Methods, 59: 199-210.
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88. Chen, C.H., N.T. Potter and N.I. Taranenko, 2004. Detection of trinucleotide repeat containing genes by Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometry. Methods Mol. Biol., 217: 91-100.
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89. Liu, Z., N.R. Isola, S.L. Allman and C.H. Chen, 2003. Biotin-enhanced fragmentation for direct deoxyribonucleic acid sequencing using matrix-assisted laser desorption/ionization mass spectrometry. Eur. J. Mass Spectrom., 9: 212-219.
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90. Isola, N.R., Z. Liu, S.L. Allman, N.I. Taranenko, Y. Kong and C.H. Chen, 2003. Matrix-assisted laser desorption/ionization detection of polymerase chain reaction products by utilizing the 5'-3' exonuclease activity of Thermus aquaticus DNA polymerase. Rapid Commun. Mass Spectrom., 17: 532-537.
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91. Taranenko, N.I., R. Hurt, J.Z. Zhou, N.R. Isola, H. Huang, S.H. Lee and C.H. Chen, 2002. Laser desorption mass spectrometry for microbial DNA analysis. J. Microbiol. Methods, 48: 101-106.
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92. Maya, L., C.H. Chen, K.A. Stevenson, E.A. Kenik, S.L. Allman and T.G. Thundat, 2002. Mass spectrometric analysis of water-soluble gold nanoclusters. J. Nanopart. Res., 4: 417-422.
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93. Gupta, R.K., S.V. Dobritsa, C.A. Stiles, M.E. Essington and Z. Liu et al., 2002. Metallohistins: A new class of plant metal-binding proteins. J. Protein Chem., 21: 529-536.
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