Dr. Fulya Ustun Alkan
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Dr. Fulya Ustun Alkan

Post-doctoral Fellow
Istanbul University-Cerrahpasa Turkey

Highest Degree
Ph.D. in Genotoxicity from Istanbul University, Turkiye

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Biography

Fulya USTUN ALKAN is working in Istanbul University at the Faculty of Veterinary Medicine Department of Pharmacology and Toxicology. Her main research interests are related to cancer therapy and Medicinal plants and nanotechnology. Also, she is serving as an associate Editor and reviewer of several journals in field of oncology, ethnopharmacology, microbiology.

Area of Interest:

Pharmacology and Toxicology
100%
Cancer Biology
62%
Toxicology
90%
Genotoxicity
75%
Cytotoxicity
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Taşaltın, N., C. Taşaltın, F. Üstün-Alkan and S. Karakuş, 2023. Biocompatible, antibacterial, and antifungal two-dimensional silicene nanosheets with a honeycomb hexagonal structure. Biomass Conv. Bioref., 10.1007/s13399-022-03726-0.
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  2. Anlas, C., T. Bakirel, O. Ustuner, F.U. Alkan and B.D. Sigirci, et al., 2023. In vitro biological activities and preliminary phytochemical screening of different extracts from Achillea sintenisii Hub- Mor. Arabian J. Chem., 10.1016/j.arabjc.2022.104426.
    CrossRef  |  Direct Link  |  
  3. Sari, A.B., Y. Gunes, C. Anlas, F.U. Alkan, E. Guncum, O. Ustuner and T. Bakirel, 2022. Effects of feed intake and water hardness on fluralaner pharmacokinetics in layer chickens. J. Vet. Sci., 10.4142/jvs.22048.
    CrossRef  |  Direct Link  |  
  4. Karakuş, S., M.A. Insel, İ.M. Kahyaoğlu, İ. Albayrak and F. Ustun-Alkan, 2022. Characterization, optimization, and evaluation of preservative efficacy of carboxymethyl cellulose/hydromagnesite stromatolite bio-nanocomposite. Cellulose, 29: 3871-3887.
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  5. Ustun-Alkan, F., T. Bakırel, O. Üstüner, C. Anlas, S. Cinar, F. Yıldırım and A. Gürel, 2021. Effects of tyrosine kinase inhibitor-masitinib mesylate on canine mammary tumour cell lines. J. Vet. Res., 65: 351-359.
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  6. Ustuner, O., C. Anlas, T. Bakirel, F. Ustun-Alkan and B.D. Sigirci et al., 2019. In vitro evaluation of antioxidant, anti-inflammatory, antimicrobial and wound healing potential of thymus Sipyleus boiss. subsp. rosulans (borbas) jalas. Molecules, Vol. 24. 10.3390/molecules24183353.
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  7. Duran, H., F.U. Alkan, M.B. Ulkay, S. Karakus, A. Aktas and T. Sismanoglu, 2019. Investigation of the in vitro cytotoxic effects and wound healing activity of ternary composite substance (hollow silica sphere/gum arabic/methylene blue). Int. J. Biol. Macromol., 121: 1194-1202.
    CrossRef  |  Direct Link  |  
  8. Anlas, C., T. Bakirel, F. Ustun-Alkan, B. Celik, M.Y. Baran, O. Ustuner and A. Kuruuzum-Uz, 2019. In vitro evaluation of the therapeutic potential of anatolian kermes oak (Quercus coccifera L.) as an alternative wound healing agent. Ind. Crops Prod., 137: 24-32.
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  9. Zarei, O., S. Benvenuti, F. Ustun-Alkan, M. Hamzeh-Mivehroud and S. Dastmalchi, 2017. Identification of a RON tyrosine kinase receptor binding peptide using phage display technique and computational modeling of its binding mode. J. Mol. Model., Vol. 23, No. 9. 10.1007/s00894-017-3437-2.
    CrossRef  |  PubMed  |  Direct Link  |  
  10. Zarei, O., M. Hamzeh-Mivehroud, S. Benvenuti, F. Ustun-Alkan and S. Dastmalchi, 2017. Characterizing the hot spots involved in RON-MSPβ complex formation using in silico alanine scanning mutagenesis and molecular dynamics simulation. Adv. Pharmaceut. Bull., 7: 141-150.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Bakirel, T., F.U. Alkan, O. Ustuner, S. Cinar, C. Anlas and A.B. Sari, 2017. Response of cultured normal canine mammary epithelial cells to deracoxib-doxorubicin combination. Acta Vet. Hung., 65: 366-381.
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  12. Anlas, F.C., O. Ustuner, F.U. Alkan, T. Bakirel, M.N. Aydogan and S.B. Erel, 2017. A comparative study on the antioxidant activities and phenolic contents of different extracts of Achillea nobilis subsp. sipylea and Alcea apterocarpa (Fenzl) Boiss, endemic plants in Turkey. Anlas, F.C., O. Ustuner, F.U. Alkan, T. Bakirel, M.N. Aydogan and S.B. Erel, 2017. A comparative stu 26: 1423-1430.
  13. Zarei, O., S. Benvenuti, F. Ustun-Alkan, M. Hamzeh-Mivehroud and S. Dastmalchi, 2016. Strategies of targeting the extracellular domain of RON tyrosine kinase receptor for cancer therapy and drug delivery. J. Cancer Res. Clin. Oncol., 142: 2429-2446.
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  14. Zarei, O., S. Benvenuti, F. Ustun-Alkan, M. Hamzeh-Mivehroud and S. Dastmalchi, 2016. Strategies of targeting the extracellular domain of RON tyrosine kinase receptor for cancer therapy and drug delivery. J. Cancer Res. Clin. Oncol. 10.1007/s00432-016-2214-4.
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  15. Bakirel, T., F.U. Alkan, O. Ustuner, S. Cinar, F. Yildirim, G. Erten and U. Bakirel, 2016. Synergistic growth inhibitory effect of deracoxib with doxorubicin against a canine mammary tumor cell line, CMT-U27. J. Vet. Med. Sci., 4: 657-668.
    CrossRef  |  Direct Link  |  
  16. Akyol, C., O. Ince, Z. Cetecioglu, F.U. Alkan and B. Ince, 2016. The fate of oxytetracycline in two-phase and single-phase anaerobic cattle manure digesters and its effects on microbial communities. J. Chem. Technol. Biotechnol., 91: 806-814.
    CrossRef  |  
  17. Bekdeser, B., M. Ozyurek, K. Guclu, F.U. Alkan and R. Apak, 2014. Development of a new catalase activity assay for biological samples using optical CUPRAC sensor. Spectrochimica Acta Part A: Mol. Biomol. Spectroscopy, 132: 485-490.
  18. Alkan, F.U., T. Bakirel, O. Ustuner and H. Yardibi, 2014. In vitro effects of doxorubicin and deracoxib on oxidative-stress-related parameters in canine mammary carcinoma cells. Acta Vet. Hungarica, 62: 372-385.
    CrossRef  |  Direct Link  |  
  19. Alkan, F.U., F.C. Anlas, S. Cinar, F. Yildirim and O. Ustuner et al., 2014. Effects of curcumin in combination with cyclophosphamide on canine mammary tumour cell lines. Vet. Med., 59: 553-572.
  20. Alkan, F.U., C. Anlas, O. Ustuner, T. Bakirel and A.B. Sari, 2014. Antioxidant and proliferative effects of aqueous and ethanolic extracts of Symphytum officinale on 3T3 Swiss albino mouse fibroblast cell line. Asian J. Plant Sci. Res., 4: 62-68.
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  21. Alkan, F.U., O. Ustuner, T. Bakirel, S. Cinar, G. Erten and G. Deniz, 2012. The effects of piroxicam and deracoxib on canine mammary tumour cell line. Scient. World J., Vol. 2012. 10.1100/2012/976740.
    CrossRef  |  Direct Link  |  
  22. Alkan, F.U., F.E. Gursel, A. Ates, M. Ozyurek, K. Guclu and M. Altun, 2012. Protective eff ects of Salvia officinalis extract against cyclophosphamide-induced genotoxicity and oxidative stress in rats. Turk. J. Vet. Anim. Sci., 36: 646-654.
    CrossRef  |  Direct Link  |  
  23. Alkan, F.U. and S. Sener, 2009. Lack of the antimutagenic effect of ascorbic acid on the genotoxicity of albendazole in mouse bone marrow cells. Bull. Vet. Inst. Pulawy, 53: 493-497.
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