Dr. Prakasha  Kempaiah
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Dr. Prakasha Kempaiah

Assistant Professor
University of New Mexico School of Medicine, America


Highest Degree
Ph.D. in Human Genetics from University of Goettingen, Germany

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Biography

Dr. Prakasha Kempaiah is currently working as Research Assistant Professor at University of New Mexico school of Medicine, America. He obtained his Ph.D. in Human Genetics from University of Goettingen, Germany. His main area of interest related to Biomedical Sciences. His area of expertise includes Molecular Biology, Genetics/ Genomics, Hematology, Biochemistry and Immunology, Protein therapy, Bio-statistics, Cell Biology, Mouse models, Infectious Diseases, and Stem Cells. He is author and co-author of 16 journal papers.

Area of Interest:

Biomedical Sciences
100%
Biochemistry
62%
Cell Biology
90%
Molecualar Biology
75%
Hematology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Rivas, A.L., M.D. Jankowski, R. Piccinini, G. Leitner and D. Schwarz et al., 2013. Feedback-based, system-level properties of vertebrate-microbial interactions. PloS One, Vol. 8. 10.1371/journal.pone.0053984.
    CrossRef  |  
  2. Kempaiah, P., L.B. Davidson, D.J. Perkins and T.F. Byrd, 2013. Cystic fibrosis CFBE41o‐cells contain TLR1 SNP I602S and fail to respond to Mycobacterium abscessus. J. Cystic Fibrosis, 12: 773-779.
    CrossRef  |  Direct Link  |  
  3. Anyona, S.B., P. Kempaiah, G.C. Davenport, J.M. Vulule, J.B. Hittner, J.M. Ongecha and D.J. Perkins, 2013. Suppressed circulating bicyclo-PGE 2 levels and leukocyte COX-2 transcripts in children co-infected with P. falciparum malaria and HIV-1 or bacteremia. Biochem. Biophys. Res. Commun., 436: 585-590.
    CrossRef  |  Direct Link  |  
  4. Ouma, C., G.C. Davenport, S. Garcia, P. Kempaiah and A. Chaudhary et al., 2012. Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children. Human Genet., 131: 289-299.
    CrossRef  |  Direct Link  |  
  5. Kempaiah, P., S.B. Anyona, E. Raballah, G.C. Davenport and T. Were et al., 2012. Reduced interferon (IFN)-α conditioned by IFNA2 (− 173) and IFNA8 (− 884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality. Human Genet., 131: 1375-1391.
    CrossRef  |  Direct Link  |  
  6. Anyona, S.B., P. Kempaiah, E. Raballah, G.C. Davenport and T. Were, 2012. Reduced systemic bicyclo‐prostaglandin‐E2 and cyclooxygenase‐2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia. Am. J. Hematol., 87: 782-789.
    CrossRef  |  Direct Link  |  
  7. Perkins, D.J., T. Were, G.C. Davenport, P. Kempaiah, J.B. Hittner and J.M. Ongecha, 2011. Severe malarial anemia: Innate immunity and pathogenesis. Int. J. Biol. Sci., 7: 1427-1442.
    Direct Link  |  
  8. Ong'echa, J.M., E.O. Raballah, P.M. Kempaiah, S.B. Anyona and T. Were et al., 2011. Polymorphic variability in the 3'untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria. BMC Genet., Vol. 12. 10.1186/1471-2156-12-69.
    Plasmodium falciparum malaria.' target='_blank'>CrossRef  |  Plasmodium falciparum malaria.' target='_blank'>Direct Link  |  
  9. Davidson, L.B., R. Nessar, P. Kempaiah, D.J. Perkins and T.F. Byrd, 2011. Mycobacterium abscessus glycopeptidolipid prevents respiratory epithelial TLR2 signaling as measured by HbetaD2 gene expression and IL-8 release. PloS One, Vol. 6. 10.1371/journal.pone.0029148.
    CrossRef  |  
  10. Awandare, G.A., P. Kempaiah, D.O. Ochiel, P. Piazza, C.C. Keller and D.J. Perkins, 2011. Mechanisms of erythropoiesis inhibition by malarial pigment and malaria‐induced proinflammatory mediators in an in vitro model. Am. J. Hematol., 86: 155-162.
    CrossRef  |  Direct Link  |  
  11. Anyona, S.B., P. Kempaiah, E. Raballah, C. Ouma and T. Were et al., 2011. Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality. Infect. Immunity, 79: 4923-4932.
  12. Mohandas, S., P. Kempaiah, M.L. Choudhary, B.N.S. Murthy and T.K.S. Gowda, 2009. Somatic embryogenesis and Agrobacterium-mediated genetic transformation of geranium with chitinase-glucanase encoding genes. Indian J. Hortic., 66: 1-6.
  13. Kempaiah, P., L.A. Danielson, M. Barry and W. Kisiel, 2009. Comparative effects of aprotinin and human recombinant R24K KD1 on temporal renal function in long-evans rats. J. Pharmacol. Exp. Therapeutics, 331: 940-945.
    CrossRef  |  Direct Link  |  
  14. Kempaiah, P., H.S. Chand and W. Kisiel, 2009. Human tissue factor pathway inhibitor-2 is internalized by cells and translocated to the nucleus by the importin system. Arch. Biochem. Biophys., 482: 58-65.
    CrossRef  |  Direct Link  |  
  15. Kempaiah, P. and W. Kisiel, 2008. Human tissue factor pathway inhibitor-2 induces caspase-mediated apoptosis in a human fibrosarcoma cell line. Apoptosis, 13: 702-715.
    CrossRef  |  Direct Link  |  
  16. Kempaiah, P., H.S. Chand and W. Kisiel, 2007. Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues. Mol. Cancer, Vol. 6. .
    Direct Link  |