Dr. Sudha Ramaiah
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Dr. Sudha Ramaiah

Associate Professor
VIT University, India

Highest Degree
Ph.D. in Bioinformatics from VIT University, India

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Biography

Dr. Sudha Ramaiah holds a position of Associate Professor at Bioinformatics Division, School Of Biosciences and Technology, VIT University, India. She has completed her PhD in Bioinformatics from same University. Her main area of interest focuses on Biosciences. Her area of expertise includes C-H…O interactions, π - π Interactions, Conservation Score, Clustering Analysis, Molecular Sequence Annotation, Multiple Drug Resistance, Anti-Malarial compounds, molecular dynamics, C-H•••π interactions, Solvent Accessibility, Stabilization Centers, Gene expression data, SNP, β-Lactamases, Molecular Docking, Antibiotic Resistance Genes, Cation- π interactions, Gene regulatory networks, Gene Ontology, Medicinal Rice, Quinolinyl Chalcone Derivatives, Database, N-H•••π interactions, Stabilizing Residues, Protein Network, AmpC β-lactamases, Molecular Dynamics Simulation, Non-classical interactions, Molecular Docking, and π-Network. She has 52 publications in journals contributed as author/co-author.

Area of Interest:

Molecular Sciences
100%
Biosciences
62%
Solvent Accessibility
90%
Protein Network
75%
Resistance Genes
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Senthilkumar, N., Y.D. Ravichandran, K.M. Kumar and S. Ramaiah, 2015. Synthesis of a new series of pyrimidine derivatives: Exploration of anti-proliferative activity on EAT cells and molecular docking. Res. Chem. Intermed, Vol. 41. 10.1007/s11164-015-2086-2.
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  2. Ravishankar, S., A. Ambady, H. Ramu, N.V. Mudugal and R. Tunduguru et al., 2015. An IPTG inducible conditional expression system for mycobacteria. PLoS One, Vol. 10. 10.1371/journal.pone.0134562.
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  3. Rajesh, K., P. Lavanya, P. Iniyavan, S. Sarveswari, S. Ramaiah, A. Anbarasu and V. Vijayakumar, 2015. Regioselective synthesis of 2-chloroquinoline based ethyl 4-(3-hydroxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylates and their in-silico evaluation against P. falciparum lactate dehydrogenase. Med. Chem., Vol. 11. .
    Direct Link  |  
  4. Lavanya, P., S. Ramaiah and A. Anbarasu, 2015. A molecular docking and dynamics study to screen potent anti-staphylococcal compounds against ceftaroline resistant MRSA. J. Cell. Biochem. 10.1002/jcb.25307.
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  5. Lavanya, P., S. Bag, S. Ramaiah and A. Anbarasu, 2015. Importance of cation-π interactions in the conformational stability and specificity of β-lactamases. J. Indian Chem. Soc., 92: 1008-1010.
  6. Kumar, C.H.V., R. Swetha, S. Ramaiah and A. Anbarasu, 2015. Tryptophan to Glycine mutation in the position 116 leads to protein aggregation and decreases the stability of the LITAF protein. J. Biomol. Struct. Dynam., 33: 1695-1709.
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  7. Krishnanunni, K., P. Senthilvel, S. Ramaiah and A. Anbarasu, 2015. Study of chemical composition and volatile compounds along with In-vitro assay of antioxidant activity of two medicinal rice varieties: Karungkuravai and Mappilai samba. J. Food Sci. Technol., 52: 2572-2584.
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  8. Kaur, P., A. Ghosh, R.V. Krishnamurthy, D.G. Bhattacharjee and V. Achar et al., 2015. A high-throughput cidality screen for mycobacterium tuberculosis. PLoS One, Vol. 10. 10.1371/journal.pone.0117577.
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  9. Bag, S., S. Ramaiah and A. Anbarasu, 2015. fabp4 is central to eight obesity associated genes: A functional gene network-based polymorphic study. J. Theoret. Biol., 364: 344-354.
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  10. Anitha, P., R.G. Swetha, A. Anbarasu and S. Ramaiah, 2015. Cation-pi interaction in metalloproteins: A bioinformatics approach. J. Indian Chem. Soc., 92: 518-520.
  11. Thillainayagam, M., L. Pandiyan, K.K. Murugan, V. Vijayaparthasarathi, S. Sundaramoorthy, A. Anbarasu and S. Ramaiah, 2014. Synthesis of quinolinyl chalcone derivatives and In-silico studies to determine the anti-malarial potential. J. Bimol. Struct. Dynam., 33: 1-17.
  12. Swetha, R.G., D.K.K. Sekar, S. Ramaiah, A. Anbarasu and K. Sekar, 2014. Haemophilus influenzae Genome Database (HIGDB): A single point web resource for Haemophilus influenzae. Comput. Biol. Med., 55: 86-91.
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  13. Swetha, R.G., D.K.K. Sekar, E.D. Devi, Z.Z. Ahmed, S. Ramaiah, A. Anbarasu and K. Sekar, 2014. Streptococcus pneumoniae Genome Database (SPGDB): A database for strain specific comparative analysis of Streptococcus pneumoniae genes and proteins. Genomics, 104: 582-586.
    CrossRef  |  Direct Link  |  
  14. Sugumar, M., K.M. Kumar, A. Manoharan, A. Anbarasu and S. Ramaiah, 2014. Detection of OXA-1 β-lactamase gene of Klebsiella pneumoniae from Blood Stream Infections (BSI) by conventional PCR and In-Silico analysis to understand the mechanism of OXA mediated resistance. PLOS One, Vol. 9. 10.1371/journal.pone.0091800.
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  15. Lavanya, P., S. Ramaiah and A. Anbarasu, 2014. Computational analysis of N-H⋯π interactions and its impact on the structural stability of β-lactamases. Comput. Biol. Med., 46: 22-28.
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  16. Lavanya, P., S. Ramaiah and A. Anbarasu, 2014. Binding site residues in β-lactamases: Role in non-classical interactions and metal binding. J. Coordinat. Chem., 67: 2898-2910.
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  17. Kumar, K.M., P. Lavanya, A. Anbarasu and S. Ramaiah, 2014. Molecular dynamics and molecular docking studies on E166A point mutant, R274N/R276N double mutant and E166A/R274N/R276N triple mutant forms of class a β-lactamases. J. Bimol. Struct. Dynam., 32: 1953-1968.
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  18. Kumar, K.M., P. Anitha, V. Sivasakthi, S. Bag, P. Lavanya, A. Anbarasu and S. Ramaiah, 2014. In silico study on penicillin derivatives and cephalosporins for upper respiratory tract bacterial pathogens. 3 Biotech, 4: 241-251.
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  19. Kumar, K.M., A. Anbarasu and S. Ramaiah, 2014. Molecular docking and molecular dynamics studies on β-lactamases and penicillin binding proteins. Mol. Biosyst., 10: 891-900.
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  20. Kumar, C.H.V., R.G. Swetha, A. Anbarasu and S. Ramaiah, 2014. Computational analysis reveals the association of Threonine 118 methionine mutation in PMP22 resulting in CMT-1A. Adv. Bioinformat. 10.1155/2014/502618.
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  21. Kumar, C.H.V., K.M. Kumar, R. Swetha, S. Ramaiah and A. Anbarasu, 2014. Protein aggregation due to nsSNP resulting in P56S VABP protein is associated with amyotrophic lateral sclerosis. J. Theoret. Biol., 354: 72-80.
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  22. Krishnanunni, K., S. Ramaiah and A. Anbarasu, 2014. Total phenolic content and in vitro antioxidant assay of two medicinal rice varieties: Karungkavuni and Kuzhiadichan. Int. J. Pharm. Bio. Sci., 5: 540-548.
  23. Jha, D.K., L. Panda, S. Ramaiah and A. Anbarasu, 2014. Evaluation and comparison of radical scavenging properties of solvent extracts from Justicia adhatoda leaf using DPPH assay. Applied Biochem. Biotechnol., 174: 2413-2425.
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  24. Bag, S., S. Ramaiah and A. Anbarasu, 2014. Network and polymorphic analysis of obesity candidate gene-plin1: A bioinformatics approach. Int. J. Human Genet., 14: 119-129.
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  25. Anitha, P., S. Bag, S. Ramaiah and A. Anbarasu, 2014. Gene and protein network analysis of AmpC β lactamase. Cell Biochem. Biophys., 5: 1553-1567.
    PubMed  |  
  26. Anitha, P., P. Lavanya, A. Anbarasu and S. Ramaiah, 2014. Molecular docking study of catechins compounds from Camellia sinensis against UPPS in Staphylococcus aureus. Int. J. Comput. Biol., 3: 3-9.
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  27. Anitha, P., A. Anbarasu and S. Ramaiah, 2014. Computational gene network study on antibiotic resistance genes of Acinetobacter baumannii. Comput. Biol. Med., 48: 17-27.
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  28. Vaideeswaran, S. and S. Ramaiah, 2013. Investigations on the role of π-π interactions and π-π networks in eNOS and nNOS proteins. Bioorg. Chem., 49: 16-23.
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  29. Sivasakthi, V., P. Anitha, K.M. Kumar, S. Bag and P. Senthilvel et al., 2013. Aromatic-aromatic interactions: Analysis of π-π interactions in interleukins and TNF proteins. Bioinformation, 9: 432-439.
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  30. Sivasakthi, V., A. Anbarasu and S. Ramaiah, 2013. π-π interactions in structural stability: Role in RNA binding proteins. Cell Biochem. Biophys., 67: 853-863.
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  31. Senthilvel, P., P. Lavanya, K.M. Kumar, R. Swetha and P. Anitha et al., 2013. Flavonoid from Carica papaya inhibits NS2B-NS3 protease and prevents Dengue 2 viral assembly. Bioinformation, 9: 889-895.
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  32. Ragavan, R.V., K.M. Kumar, V. Vijayakumar, S. Sarveswari and S. Ramaiah et al., 2013. β-Keto esters from ketones and ethyl chloroformate: A rapid, general, efficient synthesis of pyrazolones and their antimicrobial, in silico and in vitro cytotoxicity studies. Organ. Med. Chem. Lett., Vol. 3. 10.1186/2191-2858-3-6.
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  33. Mahalakshmi, T. and S. Ramaiah, 2013. Targets to combat obesity: An review. Int. J. Pharm. BioSci., 4: 795-809.
  34. Lavanya, P., S. Ramaiah and A. Anbarasu, 2013. Non-canonical H-bonds in β-lactamases: Importance of C-H...π interactions. J. Biol. Inorganic Chem., 1: 539-545.
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  35. Lavanya, P., S. Ramaiah and A. Anbarasu, 2013. Influence of C-H...O interactions on the structural stability of β-lactamases. J. Biol. Phys., 39: 649-663.
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  36. Bag, S., A. Kundu, S. Ramaiah and A. Anbarasu, 2013. Obesity study among patients in eastern India suggests WC and WHR as better indicators. Int. J. Pharm. Pharmaceut. Sci., 5: 659-665.
    Direct Link  |  
  37. Kundu, A., S. Ramaiah and A. Anbarasu, 2012. Mutation in angiotensin II type 1 receptor disrupts its binding to angiotensin II leading to hypotension: An insight into hydrogen bonding patterns. Front. Biol., 7: 477-484.
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  38. Kundu, A., S. Bag, S. Ramaiah and A. Anbarasu, 2012. Leucine to proline substitution by SNP at position 197 in caspase-9 gene expression leads to neuroblastoma: A bioinformatics analysis. 3 Biotech, 3: 225-234.
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  39. Jha, D.K., L. Panda, P. Lavanya, S. Ramaiah and A. Anbarasu, 2012. Detection and confirmation of alkaloids in leaves of Justicia adhatoda and bioinformatics approach to elicit its anti-tuberculosis activity. Applied Biochem. Biotechnol., 168: 980-990.
    CrossRef  |  Direct Link  |  
  40. Anitha, P., V. Sivasakthi, P. Lavanya, S. Bag, K.M. Kumar, A. Anbarasu and S. Ramaiah, 2012. Arginine and lysine interactions with π residues in metalloproteins. Bioinformation, 8: 820-826.
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  41. Sivasakthi, V. and S. Ramaiah, 2011. Experimental and computational techniques in protein interactions. Int. J. Pharma BioSci., 2: 122-132.
  42. Kumar, K.M. and S. Ramaiah, 2011. Pharmacological importance of Echinacea purpurea. Int. J. Pharma BioSci., 2: 304-314.
    Direct Link  |  
  43. Anitha, P. and S. Ramaiah, 2011. β-lactamase in acinetobacter species: A global threat. Int. J. Pharma BioSci., 2: 759-770.
  44. Ramaiah, S., A. Anbarasu and R. Sethumadhavan, 2010. Evaluation of non-covalent interaction energies for neuronal and endothelial NOS proteins. Int. J. Soft Comput. Bioinformat., 1: 29-36.
  45. Ramaiah, S., A. Anbarasu and R. Sethumadhavan, 2009. Exploring the C-H...O interactions in glycoproteins. Applied Biochem. Biotechnol., 159: 343-354.
    CrossRef  |  Direct Link  |  
  46. Ramaiah, S., A. Anbarasu and R. Sethumadhavan, 2008. Non-classical hydrogen bonds in interleukins: The role of C-H⋯O interactions. Int. J. Biol. Macromol., 43: 468-473.
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  47. Ramaiah, S., A. Anbarasu and R. Sethumadhavan, 2008. Influence of C-H...π hydrogen bonds in interleukins. In Silico Biol., 8: 261-273.
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  48. Anbarasu A., S. Ramaiah and R. Sethumadhavan, 2008. N-H...π interactions: Investigations on the evidence and consequences in RNA binding proteins. Open Struct. Biol. J., 2: 33-42.
  49. Anbarasu, A., S. Ramaiah, M.M. Babu and R. Sethumadhavan, 2007. Investigations on C-H...π interactions in RNA binding proteins. Int. J. Biol. Macro, 41: 251-259.
    CrossRef  |  Direct Link  |  
  50. Anbarasu, A., S. Ramaiah, L. Mathew and R. Sethumadhavan, 2007. Influence of cation-π interactions on RNA-binding proteins. Int. J. Biol. Macro, 40: 479-483.
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  51. Anbarasu, A., S. Ramaiah and R. Sethumadhavan, 2007. Investigations on unconventional hydrogen bonds in RNA binding proteins: The role of CH...O=C interactions. BioSystems, 90: 792-801.
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  52. Anbarasu, A., S. Ramaiah, L. Mathew and R. Sethumadhavan, 2006. Computation of non-covalent interactions in TNF proteins and interleukins. Cytokines, 35: 263-269.
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