Biography

Kishore Polireddy, Ph.D. is a postdoctoral research fellow at the University of Texas Health Science Center Houston. Polireddy received his Master’s degree in Biology from The Western Kentucky University and his PhD in Toxicology from the University of Kansas Medical Center under the supervision of Dr.Qi Chen. Polireddy gained extensive knowledge in cancer biology field during his PhD. His recent research activities include identification of functional significance of ABCB6 over expression to hepatocellular carcinoma, studying the mechanism of anticancer activities of high dose ascorbate, developing novel ascorbate combination treatments for pancreatic cancer patients, developing novel epithelial to mesenchymal transition inhibitors for targeting pancreatic cancer stem cells. Currently he is trying to identify the functional significance of mutant p53 in induction of pancreatic ductal adenocarcinoma from ductal epithelial cells. Polireddy serves on the editorial boards of The American Journal of Science and Medical Research, Biolife Journal. He is also serving as reviewer for journals Onco Targets and Therapy, Chinese medicine, Journal of Hepatocellular Carcinoma, Narayana Medical Journal, Cancer Research Journal, Journal of Cancer Treatment and Research, Cancer Science and Research, Patient preference and adherence, American Journal of Medical Case Reports, Archives in cancer research, Journal of Nutritional Health and Food Science, Journal of Cancer Research and Treatment. He has authored or co-authored over 10 manuscripts and received young investigator award from the Society of Integrative Oncology for his outstanding work on understanding the anticancer activities of high dose ascorbate. This work has been featured in both national and international media.

Area of Interest:

Pharmacology and Toxicology

100%

Chinese Medicine

62%

Cell Biology

90%

Breast Cancer

75%

Cancer Research

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
0

Abstracts
0

Selected Publications

Ramesh, P., D. Srinivasulu, P. Kishore, R.V. Koteswara and B.R.M. Vijaya, 2015. Synthesis, spectral characterization and anticancer activity of new 2, 3, 6-substituted quinazolin-4 (3h)-one derivatives. Lett. Org. Chem., 12: 385-393.
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Polireddy. K., P.R. McDonald, B. Luke, R. Dong, M. Broward, A. Roy, Q. Chen, 2015. Targeting epithelial-mesenchymal transition for identification of inhibitors for Anti. Cancer Drugs Rev., .
Polireddy, K., R. Dong, J. Yu, W. Stephen, J. Drisjo and Q. Chen, 2015. Mechanisms of ascorbate inhibiting pancreatic cancer metastasis. Cell Cycle Under Rev., .
Fukui, M., N. Yamabe, H.J. Choi, K. Polireddy, Q. Chen and B.T. Zhu, 2015. Mechanism of ascorbate-induced cell death in human pancreatic cancer cells: Role of bcl-2, beclin 1 and autophagy. Planta Med., 81: 838-846.
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Chen, Q., K. Polireddy, P. Chen and R. Dong, 2015. An unpaved journey of vitamin C in cancer treatment. Can. J. Physiol. Pharmacol., 93: 1055-1063.
Direct Link |
Reddy, A.L and K. Polireddy, 2013. Importance of stroma in breast cancer. J. Clin. Sci. Res., 3: 56-57.
Rani, V.J., R. Aminedi, K. Polireddy and K. Jagadeeswarareddy, 2012. Synthesis and spectral characterization of new bis (2-(pyrimidin-2-yl) ethoxy) alkanes and their pharmacological activity. Arch. Pharm., 345: 663-669.
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Rani, V.J., A. Raghavendra, P. Kishore, Y.N. Kumar, K.H. Kumar and K. Jagadeeswarareddy, 2012. Synthesis and biological activity evaluation of cytidine-5'-deoxy-5-fluoro-N-[(alkoxy/aryloxy)] carbonyl-cyclic 2', 3'-carbonates. Eur. J. Med. Chem., 54: 690-696.
CrossRef | PubMed | Direct Link |
Babu, K.R., V.K. Rao, Y.N. Kumar, K. Polireddy and K.V. Subbaiah et al., 2012. Identification of substituted [3, 2-a] pyrimidines as selective antiviral agents: molecular modeling study. Antiviral Res., 95: 118-127.
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Polireddy, K., H. Chavan, B.A. Abdulkarim and P. Krishnamurthy, 2011. Functional significance of the ATP-binding cassette transporter B6 in hepatocellular carcinoma. Mol. Oncol., 5: 410-425.
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