Dr. Kumarappan Chidambaram
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Dr. Kumarappan Chidambaram

Assistant Professor
Department of Pharmacology College of Pharmacy, King Khalid University, Saudi Arabia.

Highest Degree
Ph.D. in Pharmacology from Jadavpur University, India

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Biography

Dr. Kumar is a research track academician and senior lecturer in the School of Pharmacy, Taylor’s University. Dr. Kumar was awarded his doctorate in pharmacology in 2008, with specialization in endocrine pharmacology, from the Department of Pharmaceutical technology, Jadavpur University, Kolkata, India. He obtained his undergraduates (BPharm, 1999) and postgraduates (MPharm, 2003) from Dr. MGR Medical University Chennai, India. Dr.Kumar has been the recipient of prestigious National Doctoral Fellowship (NDF) from AICTE, Government of India. Now Dr. Kumar has been directed his on animal and non-animal models of metabolic syndrome as well as natural products. Dr.Kumar’s research mainly focuses on the investigation of cellular and molecular mechanisms of high fructose corn syrup induced metabolic abnormalities and development of potent molecules for the treatment of metabolic syndrome and insulin resistance. Kumar has almost 11 years of research experience in the field of endocrine (Diabetic) pharmacology and has worked in collaboration with academic scientists and herbal industry collaborators. Dr. Kumar has approximately 50 peer-reviewed publications including review articles on metabolic disorders, obesity and diabetes mellitus and contributed to one book chapter with an overall H-index of 10. He serves on the editorial board member of numerous medical and pharmacological journals and has reviewed more than 50 peer-reviewed articles. His current research on metabolic syndrome has been supported by Ministry of Ministry of Higher Education (MOHE) and Ministry of Science, Technology and Innovation (MOSTI), Government of Malaysia. Dr. Kumar is also actively involved in teaching various pharmacological modules and courses on central and peripheral nervous system to graduate and undergraduate students. He has also supervised and mentored several undergraduates and postgraduates in various pharmacological research activities. Dr. Kumar has served as a chief and co-investigator on a number of research projects funded by university and government of Malaysia. In 2008-2010, Dr.Kumar has served the University College (The Erode College of Pharmacy) in an administrative capacity as Head of the Animal House and Secretary of the Institutional Animal Ethical Committee (IAEC), is responsible for ensuring the humane care and use of research animals and for ascertaining that researchers at University College adhere to all (Committee for the Purpose of Control and Supervision of Experiments on Animals) CPCSEA, New Delhi, India, regulations and policies, in part, enable the University College to approve postgraduate associated animal research.

Area of Interest:

Pharmacology and Toxicology
100%
Metabolic Syndrome
62%
Obesity
90%
Diabetes Mellitus
75%
Alzheimer`s Disease
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
10
Abstracts
0

Selected Publications

  1. Kumarappan, C.T. and S.C. Mandal, 2015. Anti-diabetic activity of polyphenolic extract of Ichnocarpus frutescens on STZ induced type II diabetic rats with reference to key carbohydrate metabolic enzymes. Int. J. Diabetes in Developing Countries, .
  2. Kumarappan, C., R. Srinivasan, S. Jeevathayaparan, R. Rajinikanth, H.S.N. Kumar, S. Senthilrajan and C.M. Subhash, 2015. Ichnocarpus frutescens: A valuable medicinal plant. Pharmacologyonline, 2: 18-37.
  3. Srinivasan, R., R.D. Senthil, G. Ashok and C.T. Kumarappan, 2014. Cytotoxic and antimicrobial activity of ipomoea obscura. Aust. J. Basic Appl. Sci., 8: 529-532.
  4. Ramamurthy, S., C. Kumarappan, S.R. Dharmalingam and J.K. Sangeh, 2014. Phytochemical, pharmacological and toxicological properties of Ficus deltoidea: A review of a recent research. Annu. Res. Rev. Biol., 4: 2357-2371.
    CrossRef  |  Direct Link  |  
  5. Kumarappan, C. and S.C. Mandal, 2014. Short communication polyphenol extract of Ichnocarpus frutescens leaves modifies hyperglycemia in dexamethasone (dex) treated rats. Indian J. Physiol. Pharmacol., 58: 441-445.
    PubMed  |  Direct Link  |  
  6. Dharmalingam, S.R., R. Madhappan, S. Ramamurthy, K. Chidambaram, M.V. Srikanth, S. Shanmugham and K.S. Kumar, 2014. Investigation on antidiarrhoeal activity of Aristolochia Indica Linn. root extracts in mice. Afr. J. Traditional Complementary Altern. Med., 11: 292-294.
  7. Dharmalingam, S.R., R. Madhappan, K. Chidambaram, S. Ramamurthy, K. Gopal, P. Swetha and K.S. Kumar, 2014. Anti-urolithiatic activity of Melia azedarach linn leaf extract in ethylene glycol-induced urolithiasis in male albino rats. Trop. J. Pharm. Res., 13: 391-397.
    CrossRef  |  Direct Link  |  
  8. Dharmalingam, S.R., K. Chidambaram, S. Ramamurthy and S. Nadaraju, 2014. Effects of nanosuspension and inclusion complex techniques on the in vitro protease inhibitory activity of naproxen. Braz. J. Pharm. Sci., 50: 165-171.
    CrossRef  |  Direct Link  |  
  9. Vijayapandia, P., V. Annabathina, B. SivaNagaSrikanth, V. Manjunath, P. Boggavarapu, K. Rajendraprasad and C.T. Kumarappan, 2013. In vitro anticholinergic and antihistaminic activities of acorus calamus linn. leaves extracts. Afr. J. Traditional Complementary Altern. Med., 10: 95-101.
    CrossRef  |  PubMed  |  Direct Link  |  
  10. Thilagam, E., B. Parimaladevi, C. Kumarappan and S.C. Mandal, 2013. α-Glucosidase and α-amylase inhibitory activity of Senna surattensis. J. Acupunct. Meridian Stud., 6: 24-30.
    Direct Link  |  
  11. Senthil-Rajan, D., M. Rajkumar, R. Srinivasan, C. Kumarappan, K. Arunkumar, K.L. Senthilkumar and M.V. Srikanth, 2013. Investigation on antimicrobial activity of root extracts of Thespesia populnea Linn. Trop. Biomed., 30: 570-578.
    PubMed  |  Direct Link  |  
  12. Rajan, D.S., M. Rajkumar, C.T. Kumarappan and K.S. Kumar, 2013. Wound healing activity of an herbal ointment containing the leaf extract of Ziziphus Mauritiana Lam. Afr. J. Pharm. Pharmacol., 7: 98-103.
    CrossRef  |  Direct Link  |  
  13. Rajagopal, S.S., G. Lakshminarayanan, R. Rajesh, S.R. Dharmalingam, S. Ramamurthy, K. Chidambaram and S. Shanmugham, 2013. Neuroprotective potential of Ocimum sanctum (Linn) leaf extract in monosodium glutamate induced excitotoxicity. Afr. J. Pharm. Pharmacol., 7: 1894-1906.
    CrossRef  |  Direct Link  |  
  14. Dharmalingam, S.R., S. Ramamurthy, K. Chidambaram and S. Nadaraju, 2013. A simple HPLC-UV bioanalytical method for the estimation of doxorubicin in rat plasma: Application to pharmacokinetic studies. Trop. J. Pharm. Res., 13: 409-415.
  15. Dharmalingam, S.R., K. Chidambaram, S. Chakravarthy and N.K. Ping, 2013. Hepatotoxic effect of doxorubicin in sprague dawley rats: Evidence from histopathological study. J. Bot. Life Sci. Res. (Bothalia), 43: 198-211.
  16. Dharmalingam, S.R., K. Chidambaram and S. Ramamurthy, 2013. Preparation and enhanced in-vitro diffusion profile of naproxen by EPAS technique in hydrogel formulation. Digest J. Nanomater. Biostruct., 8: 25-33.
    Direct Link  |  
  17. Sunil, C., S. Ignacimuthu and C. Kumarappan, 2012. Hypolipidemic activity of Symplocos cochinchinensis S. Moore leaves in hyperlipidemic rats. J. Nat. Med., 66: 32-38.
    CrossRef  |  PubMed  |  Direct Link  |  
  18. Sunil, C., P. Agastian, C. Kumarappan and S. Ignacimuthu, 2012. In vitro antioxidant, antidiabetic and antilipidemic activities of Symplocos cochinchinensis (Lour.) S. Moore bark. Food Chem. Toxicol., 50: 1547-1553.
    CrossRef  |  PubMed  |  Direct Link  |  
  19. Kumarappan, C.T., E. Thilagam, M. Vijayakumar and S.C. Mandal, 2012. Modulatory effect of polyphenolic extracts of Ichnocarpus frutescens on oxidative stress in rats with experimentally induced diabetes. Indian J. Med. Res., 136: 815-821.
    PubMed  |  Direct Link  |  
  20. Kumarappan, C.T., E. Thilagam and S.C. Mandal, 2012. Antioxidant activity of polyphenolic extracts of Ichnocarpus frutescens. Saudi J. Biol. Sci., 19: 349-355.
    CrossRef  |  PubMed  |  Direct Link  |  
  21. Ananda, P.K., C.T. Kumarappan, S. Christudas and V.K. Kalaichelvan, 2012. Effect of Biophytum sensitivum on streptozotocin and nicotinamide-induced diabetic rats. Asian Pac. J. Trop. Biomed., 2: 31-35.
    CrossRef  |  Direct Link  |  
  22. Kumarapppan, C., A. Jaswanth and K. Kumarasunderi, 2011. Antihaemolytic and snake venom neutralizing effect of some Indian medicinal plants. Asian Pac. J. Trop. Med., 4: 743-747.
    CrossRef  |  PubMed  |  Direct Link  |  
  23. Kumarappan, C., M. Vijayakumar, E. Thilagam, M. Balamurugan and M. Thiagarajan, 2011. Protective and curative effects of polyphenolic extracts from Ichnocarpus frutescense leaves on experimental hepatotoxicity by carbon tretrachloride and tamoxifen. Ann. Hepatol., 10: 63-72.
    CrossRef  |  PubMed  |  Direct Link  |  
  24. Chandra, R., C.T. Kumarappan, J. Kumar and S.C. Mandal, 2010. Antipyretic activity of JURU-01-a polyherbal formulation. Global J. Pharmacol., 4: 45-47.
    Direct Link  |  
  25. Anbarasan, V., C.T. Kumarappan and V.R. Ravikumar, 2010. Pharmacognostical and preliminary phytochemical studies on Algae Spirulina platensis nordet. J. Pharm. Res., 3: 2750-2751.
  26. Kumarappan, C.T., S. Senthil, M. Thiagarajan, M. Balamurugan, M. Radhakrishnan and S.C. Mandal, 2009. Anti-carcinoma activity of polyphenolic extract of ichnocarpus frutescens. Planta Medica, Vol. 75. .
  27. Thalapaneni, N.R., K.A. Chidambaram, T. Ellappan, M.L. Sabapathi and S.C. Mandal, 2008. Inhibition of carbohydrate digestive enzymes by Talinum portulacifolium (Forssk) leaf extract. J. Complement. Integr. Med., Vol. 5. 10.2202/1553-3840.1120.
    CrossRef  |  Direct Link  |  
  28. Rao, N.T., C. Kumarappan, M.S. Lakshmi and S.C. Mandal, 2008. Antioxidant activity of Talinum portulacifolium (Forssk) leaf extracts. Orient. Pharm. Exp. Med., 8: 329-338.
  29. Raja, N.L., S. Sundaranathavalli, J.J. Ananthi, C.T. Kumarappan, P. Kumaraguruparan and K. Yaseen, 2008. Antihyperglycemic activity of aqueous extract of vinca rosea linn in alloxan induced diabetic rats. Pharmacologyonline, 3: 354-362.
  30. Kumarappan, C.T. and S.C. Mandal, 2008. Polyphenolic extract of Ichnocarpus frutescens attenuates diabetic complications in streptozotocin-treated diabetic rats. Renal Fail., 30: 307-322.
    CrossRef  |  Direct Link  |  
  31. Kumarappan, C. and S.C. Mandal, 2008. α-glucosidase inhibitory activity and in vitro antioxidant activities of alcohol-water extract (AWE) of Ichnocarpus frutescens leaves. Med. Chem. Res., 17: 219-233.
    CrossRef  |  Direct Link  |  
  32. Nageswara Rao, T., C.T. Kumarappan, S. Mohana lakshmi and S.C. Mandal, 2007. Antidiabetic activity of leaves of Talinum portulacifolium (forssk) in alloxan-induced diabetic rats. Pharmacologyonline, 2: 407-417.
  33. Lalhlenmawia, H., C.T. Kumarappan, B.B. Bhattacharjee and S.C. Mandal, 2007. Antidiabetic activity of Mallotus roxburghianus leaves in diabetic rats induced by streptozocin. Pharmacologyonline, 3: 244-254.
  34. Kumarappan, C.T., T.N. Rao and S.C. Mandal, 2007. Polyphenolic extract of Ichnocarpus frutescens modifies hyperlipidemia status in diabetic rats. J. Cell Mol. Biol., 6: 175-187.
    Direct Link  |  
  35. Kumarappan, C.T., S. Sunderi, A. Jaswanth, S.M. Lakshmi and S.C. Mandal, 2007. Anti-tumor effect of Euphorbia hirta on Ehrlich's ascites carcinoma in mice. Orient. Pharm. Exp. Med., 7: 133-140.
  36. Kumarappan, C.T. and S.C. Mandal, 2007. Antitumor activity of polyphenolic extract of Ichnocarpus frutescens. Exp. Oncol., 29: 94-101.
  37. Kumarappan, C.T., R. Chandra and S.C. Mandal, 2006. Anti-inflammatory activity of Ichnocarpus frutescens. Pharmacologyonline, 3: 201-216.

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